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The map label for this gene is epsH [H]

Identifier: 37678402

GI number: 37678402

Start: 230344

End: 231048

Strand: Direct

Name: epsH [H]

Synonym: VV0218

Alternate gene names: 37678402

Gene position: 230344-231048 (Clockwise)

Preceding gene: 37678401

Following gene: 37678403

Centisome position: 6.87

GC content: 50.78

Gene sequence:

>705_bases
GTGCAGATGGTCAAGAAGGCGGTGAAGGCGCAGCGGCAGATATTGGCAACTGGAACATGCAAGACTTCCAATAATGGGAC
GTCGAGTCGAAGAGGCAACCACTTGAAACCACGTTTTTCATCTCGCTTAGCGGGTTTTACACTGATCGAAATTCTGTTGG
TGCTGGTGTTGTTGTCTCTGACTGCGGTGGCGGTTATCGCCACCCTTCCCACTCGCAGTGACGAGCGGGGCAAGAAATAC
GCGCAGAGTTTTTACCAACGATTACAGCTCCTCAACGAAGAGGCGGTGCTCAGTGGTAAAGATTTTGGTGTTCGGATCGA
GGAAGAAAAATCACGCTACACCTTACTCAAATTGGAAGCCGATGGCTGGCAGACGTTGGAGTTGAATAAAATCCCCGCCA
CCACCGAGCTTGAAGATGAGGTCGCGATGCAACTGACCTTAGGGGGAGGAGCGTGGCAGCAAGACGATCGCCTGTTCAAG
CCAGGCTCTCTGTTTGATGAAGAGATGTTTGCCGATGAAGAAAAAGAGAAAAAACAGCGACCGCCGCAGATTTTCATTTT
ATCCAGCGGAGAATTGACGCCGTTTTCATTGTCTTTTTATCCCGACGATCAGGACGCGACCGAAAATGGTTGGCGAGTAC
GAGCCAAAGACACAGGGCAGATTATTCTGCTGGCCCCCGGTGAAGAAGAGCAAGACGATGGTTAA

Upstream 100 bases:

>100_bases
GATGGCGGTTACATCAAGCGTCTGCCAAAAGACCCTTGGGGTAACGAATACCAATACATGAGCCCTGGCGACAAAGGCAC
GATTGATATCTTCACCTTAG

Downstream 100 bases:

>100_bases
ACGACGCAAATACGCAGGCATGACCTTGCTTGAGGTGCTGGTGGCGTTGGCGATATTTGCCACTGCGGCGATGAGCGTGA
TTCGTGCGGTTAGCCAGCAC

Product: type II secretory pathway, pseudopilin EpsH

Products: NA

Alternate protein names: Cholera toxin secretion protein epsH [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MQMVKKAVKAQRQILATGTCKTSNNGTSSRRGNHLKPRFSSRLAGFTLIEILLVLVLLSLTAVAVIATLPTRSDERGKKY
AQSFYQRLQLLNEEAVLSGKDFGVRIEEEKSRYTLLKLEADGWQTLELNKIPATTELEDEVAMQLTLGGGAWQQDDRLFK
PGSLFDEEMFADEEKEKKQRPPQIFILSSGELTPFSLSFYPDDQDATENGWRVRAKDTGQIILLAPGEEEQDDG

Sequences:

>Translated_234_residues
MQMVKKAVKAQRQILATGTCKTSNNGTSSRRGNHLKPRFSSRLAGFTLIEILLVLVLLSLTAVAVIATLPTRSDERGKKY
AQSFYQRLQLLNEEAVLSGKDFGVRIEEEKSRYTLLKLEADGWQTLELNKIPATTELEDEVAMQLTLGGGAWQQDDRLFK
PGSLFDEEMFADEEKEKKQRPPQIFILSSGELTPFSLSFYPDDQDATENGWRVRAKDTGQIILLAPGEEEQDDG
>Mature_234_residues
MQMVKKAVKAQRQILATGTCKTSNNGTSSRRGNHLKPRFSSRLAGFTLIEILLVLVLLSLTAVAVIATLPTRSDERGKKY
AQSFYQRLQLLNEEAVLSGKDFGVRIEEEKSRYTLLKLEADGWQTLELNKIPATTELEDEVAMQLTLGGGAWQQDDRLFK
PGSLFDEEMFADEEKEKKQRPPQIFILSSGELTPFSLSFYPDDQDATENGWRVRAKDTGQIILLAPGEEEQDDG

Specific function: Required for secretion of cholera toxin through the outer membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP H family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002416
- InterPro:   IPR012902
- InterPro:   IPR001120
- InterPro:   IPR022346 [H]

Pfam domain/function: PF12019 GspH [H]

EC number: NA

Molecular weight: Translated: 26256; Mature: 26256

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00409 PROKAR_NTER_METHYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMVKKAVKAQRQILATGTCKTSNNGTSSRRGNHLKPRFSSRLAGFTLIEILLVLVLLSL
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TAVAVIATLPTRSDERGKKYAQSFYQRLQLLNEEAVLSGKDFGVRIEEEKSRYTLLKLEA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCHHHHCCCCCCCEEEECCCCCEEEEEEEC
DGWQTLELNKIPATTELEDEVAMQLTLGGGAWQQDDRLFKPGSLFDEEMFADEEKEKKQR
CCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCEECCCCCCCHHHHCCCHHHHHCC
PPQIFILSSGELTPFSLSFYPDDQDATENGWRVRAKDTGQIILLAPGEEEQDDG
CCEEEEEECCCCCEEEEEECCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MQMVKKAVKAQRQILATGTCKTSNNGTSSRRGNHLKPRFSSRLAGFTLIEILLVLVLLSL
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TAVAVIATLPTRSDERGKKYAQSFYQRLQLLNEEAVLSGKDFGVRIEEEKSRYTLLKLEA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCHHHHCCCCCCCEEEECCCCCEEEEEEEC
DGWQTLELNKIPATTELEDEVAMQLTLGGGAWQQDDRLFKPGSLFDEEMFADEEKEKKQR
CCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCEECCCCCCCHHHHCCCHHHHHCC
PPQIFILSSGELTPFSLSFYPDDQDATENGWRVRAKDTGQIILLAPGEEEQDDG
CCEEEEEECCCCCEEEEEECCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]