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The map label for this gene is ubiB [C]

Identifier: 37523981

GI number: 37523981

Start: 4640468

End: 4642156

Strand: Reverse

Name: ubiB [C]

Synonym: gll4412

Alternate gene names: 37523981

Gene position: 4642156-4640468 (Counterclockwise)

Preceding gene: 37523983

Following gene: 37523980

Centisome position: 99.64

GC content: 62.23

Gene sequence:

>1689_bases
GTGAGCAGCACCCACCTCGCAAGCATTCAGGATCTGCGCAGCTACGATCCCCAACTCATAGGCGCCTACTACCGCAGACG
TCCGCTGGTGATTTTACGCCGTGCCCTCGCTGTGAGCTTTGCCTTTTTGATCTTTGGCCTGCAGCTCTGGGGGGACAAGC
TGAGCGGCTCTATCGAGCGCAACCGGCGCAAGCGGGCGTCGCAACTGCGGCAGTTGCTCACCGACCTCGGTCCCGGCAGC
ATCAAGGTGGGTCAGGCGCTCTCGACGCGGCCGGATCTGCTGCCCAAGGACTACATGGAGGAGATGACCCGGCTGCAGGA
TCAGCTGCCTCCTTTCGATAACGCGGTCGCCTTCGAGTACATCAAAAGCGAACTGGGCCGCCCCGCCCAAGAAGTTTTCG
CCCGCATCGACCCGACGCCGGTGGCCGCCGCCTCGCTGGGACAGGTTTACCGTGCCCAACTGCACACCGGCGAAAAGGTG
GCCGTCAAAGTGCAGCGCCCCGACCTGGTGGGCAAGCTCACCCTCGACCTGACCCTGTTGCGCTGGTTTTGCGCGCGCTT
CGCAGGCCGGCTGCCGTTGAATCTGGGCCACGACCTGGCGAGCATCGTCGATGAATTCGGCAACAAGCTTTTTGAAGAGA
TCGACTACGAAAACGAAGCGACCAACGCCGAGCGCTTCGCCCGCTACTTCGAGAGCGACCCGACCGTTTATGTGCCCAGG
ATCTACCGCGACTACAGCAGCCGCAAAGTGCTCACCCTGGAGTGGATCGACGGCATTAAGCTCACCGATGTCGCCGCGGT
CAAAGCCGCCGGGCTCGACATCGAATCGCTGGTGCGCATCGGCGTCGAGGCAGGCCTCAAGCAGCTTTTGGAATACGGAT
TTTTTCATGCCGACCCGCACCCGGGCAACCTGTTTGCGATGCGCGACGGCCGCATGGCCTACATCGACTTCGGGATGATG
GACCAGCTTTCGGAGGAAACTAAAGAAAACCTCGTCGATTCGCTGGTGCACCTGATTAACCGCGAGTACAAGGCGCTTGC
CCACGATTACGTCAAACTGGGCTTTCTCGCCCCCGGCACCGACGTGGCTCCCATCGTGCCCGCCCTGGAATTGGTTCTGG
GGGACATCATCGGCCAGAAGGTCCAGGATTTTAACTTCAAGACGATCACCGATCGTTTTTCGGACCTGGTGTACGAGTAC
CCCTTCCGGGTGCCCGCCAAGTTCGCGCTGATCATCCGTTCGCTGATCACCCAGGAGGGAATCGCCCTCTCGCTGACCCC
CGATTTTAAGATTATCCAGGTGGCTTACCCCTACGTGGCCCGCCGCCTGCTCACCGGCGAATCGCCCCGGTTGCGCCAGC
GTCTGCTGGATATTCTCTTCAAAGACGGCCGCTTCCAGTGGCACCGCCTCGAAAACCTCATCCAGATCGCAGGCACCGGC
GGCAGTTTCGACCTGCTGCCCGCGGCTCAGTACGGCCTCGAATCGCTGTTTTCCAAGGACGGATCCTTTATCCGTGAGCG
GTTGGTGCTGGCCCTTACCGAGGGCGACCGCCTGCACACTCACGAGCTGGGGCGTCTCTGGAATCTGGTCCGCCCGGCCA
TCCAGCCGCGCAAGCTCGTCGATCAGGCCCTCGACCGCCTGCGCGAGCGCCTCACCCCCCCGGCCGCCCAGCCCGTCCTG
CGCAGCTAA

Upstream 100 bases:

>100_bases
TGTAGCCGGGCGAACATTTTGCCGTCTGCACGTTGATCCGCGGTGAAGAATCGGTGACAATGGTAAAAAGAAGTTAACTT
TCGTTTAAAGCCGTACCGGC

Downstream 100 bases:

>100_bases
AGGGCTTTACCGGGCGTTCAGGTCGAACTCGCCCAGGATCTCGACGAGGTTGTCCATCGCCGCGGGAGCGTCTTCTGCCA
TCAGGGTAGTTGTCACGGTC

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 562; Mature: 561

Protein sequence:

>562_residues
MSSTHLASIQDLRSYDPQLIGAYYRRRPLVILRRALAVSFAFLIFGLQLWGDKLSGSIERNRRKRASQLRQLLTDLGPGS
IKVGQALSTRPDLLPKDYMEEMTRLQDQLPPFDNAVAFEYIKSELGRPAQEVFARIDPTPVAAASLGQVYRAQLHTGEKV
AVKVQRPDLVGKLTLDLTLLRWFCARFAGRLPLNLGHDLASIVDEFGNKLFEEIDYENEATNAERFARYFESDPTVYVPR
IYRDYSSRKVLTLEWIDGIKLTDVAAVKAAGLDIESLVRIGVEAGLKQLLEYGFFHADPHPGNLFAMRDGRMAYIDFGMM
DQLSEETKENLVDSLVHLINREYKALAHDYVKLGFLAPGTDVAPIVPALELVLGDIIGQKVQDFNFKTITDRFSDLVYEY
PFRVPAKFALIIRSLITQEGIALSLTPDFKIIQVAYPYVARRLLTGESPRLRQRLLDILFKDGRFQWHRLENLIQIAGTG
GSFDLLPAAQYGLESLFSKDGSFIRERLVLALTEGDRLHTHELGRLWNLVRPAIQPRKLVDQALDRLRERLTPPAAQPVL
RS

Sequences:

>Translated_562_residues
MSSTHLASIQDLRSYDPQLIGAYYRRRPLVILRRALAVSFAFLIFGLQLWGDKLSGSIERNRRKRASQLRQLLTDLGPGS
IKVGQALSTRPDLLPKDYMEEMTRLQDQLPPFDNAVAFEYIKSELGRPAQEVFARIDPTPVAAASLGQVYRAQLHTGEKV
AVKVQRPDLVGKLTLDLTLLRWFCARFAGRLPLNLGHDLASIVDEFGNKLFEEIDYENEATNAERFARYFESDPTVYVPR
IYRDYSSRKVLTLEWIDGIKLTDVAAVKAAGLDIESLVRIGVEAGLKQLLEYGFFHADPHPGNLFAMRDGRMAYIDFGMM
DQLSEETKENLVDSLVHLINREYKALAHDYVKLGFLAPGTDVAPIVPALELVLGDIIGQKVQDFNFKTITDRFSDLVYEY
PFRVPAKFALIIRSLITQEGIALSLTPDFKIIQVAYPYVARRLLTGESPRLRQRLLDILFKDGRFQWHRLENLIQIAGTG
GSFDLLPAAQYGLESLFSKDGSFIRERLVLALTEGDRLHTHELGRLWNLVRPAIQPRKLVDQALDRLRERLTPPAAQPVL
RS
>Mature_561_residues
SSTHLASIQDLRSYDPQLIGAYYRRRPLVILRRALAVSFAFLIFGLQLWGDKLSGSIERNRRKRASQLRQLLTDLGPGSI
KVGQALSTRPDLLPKDYMEEMTRLQDQLPPFDNAVAFEYIKSELGRPAQEVFARIDPTPVAAASLGQVYRAQLHTGEKVA
VKVQRPDLVGKLTLDLTLLRWFCARFAGRLPLNLGHDLASIVDEFGNKLFEEIDYENEATNAERFARYFESDPTVYVPRI
YRDYSSRKVLTLEWIDGIKLTDVAAVKAAGLDIESLVRIGVEAGLKQLLEYGFFHADPHPGNLFAMRDGRMAYIDFGMMD
QLSEETKENLVDSLVHLINREYKALAHDYVKLGFLAPGTDVAPIVPALELVLGDIIGQKVQDFNFKTITDRFSDLVYEYP
FRVPAKFALIIRSLITQEGIALSLTPDFKIIQVAYPYVARRLLTGESPRLRQRLLDILFKDGRFQWHRLENLIQIAGTGG
SFDLLPAAQYGLESLFSKDGSFIRERLVLALTEGDRLHTHELGRLWNLVRPAIQPRKLVDQALDRLRERLTPPAAQPVLR
S

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393593, Length=266, Percent_Identity=33.0827067669173, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI40254938, Length=294, Percent_Identity=29.2517006802721, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI217035081, Length=296, Percent_Identity=27.3648648648649, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI27363457, Length=343, Percent_Identity=24.4897959183673, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI34147522, Length=347, Percent_Identity=25.0720461095101, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI217416386, Length=282, Percent_Identity=24.822695035461, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI32261307, Length=409, Percent_Identity=22.9828850855746, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI2367309, Length=429, Percent_Identity=31.4685314685315, Blast_Score=202, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI17559152, Length=279, Percent_Identity=29.3906810035842, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI32565180, Length=289, Percent_Identity=27.681660899654, Blast_Score=79, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323282, Length=237, Percent_Identity=29.535864978903, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6321319, Length=325, Percent_Identity=26.1538461538462, Blast_Score=101, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6325148, Length=305, Percent_Identity=25.5737704918033, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24662575, Length=272, Percent_Identity=33.0882352941176, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI22024280, Length=295, Percent_Identity=29.8305084745763, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI18859849, Length=348, Percent_Identity=25.2873563218391, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 63706; Mature: 63575

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTHLASIQDLRSYDPQLIGAYYRRRPLVILRRALAVSFAFLIFGLQLWGDKLSGSIER
CCCCHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
NRRKRASQLRQLLTDLGPGSIKVGQALSTRPDLLPKDYMEEMTRLQDQLPPFDNAVAFEY
HHHHHHHHHHHHHHHCCCCCEECCCHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHH
IKSELGRPAQEVFARIDPTPVAAASLGQVYRAQLHTGEKVAVKVQRPDLVGKLTLDLTLL
HHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHH
RWFCARFAGRLPLNLGHDLASIVDEFGNKLFEEIDYENEATNAERFARYFESDPTVYVPR
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEECH
IYRDYSSRKVLTLEWIDGIKLTDVAAVKAAGLDIESLVRIGVEAGLKQLLEYGFFHADPH
HHHCCCCCEEEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
PGNLFAMRDGRMAYIDFGMMDQLSEETKENLVDSLVHLINREYKALAHDYVKLGFLAPGT
CCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCC
DVAPIVPALELVLGDIIGQKVQDFNFKTITDRFSDLVYEYPFRVPAKFALIIRSLITQEG
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
IALSLTPDFKIIQVAYPYVARRLLTGESPRLRQRLLDILFKDGRFQWHRLENLIQIAGTG
EEEEECCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
GSFDLLPAAQYGLESLFSKDGSFIRERLVLALTEGDRLHTHELGRLWNLVRPAIQPRKLV
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHCCCHHHHH
DQALDRLRERLTPPAAQPVLRS
HHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SSTHLASIQDLRSYDPQLIGAYYRRRPLVILRRALAVSFAFLIFGLQLWGDKLSGSIER
CCCHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
NRRKRASQLRQLLTDLGPGSIKVGQALSTRPDLLPKDYMEEMTRLQDQLPPFDNAVAFEY
HHHHHHHHHHHHHHHCCCCCEECCCHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHH
IKSELGRPAQEVFARIDPTPVAAASLGQVYRAQLHTGEKVAVKVQRPDLVGKLTLDLTLL
HHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHH
RWFCARFAGRLPLNLGHDLASIVDEFGNKLFEEIDYENEATNAERFARYFESDPTVYVPR
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEECH
IYRDYSSRKVLTLEWIDGIKLTDVAAVKAAGLDIESLVRIGVEAGLKQLLEYGFFHADPH
HHHCCCCCEEEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
PGNLFAMRDGRMAYIDFGMMDQLSEETKENLVDSLVHLINREYKALAHDYVKLGFLAPGT
CCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCC
DVAPIVPALELVLGDIIGQKVQDFNFKTITDRFSDLVYEYPFRVPAKFALIIRSLITQEG
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
IALSLTPDFKIIQVAYPYVARRLLTGESPRLRQRLLDILFKDGRFQWHRLENLIQIAGTG
EEEEECCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
GSFDLLPAAQYGLESLFSKDGSFIRERLVLALTEGDRLHTHELGRLWNLVRPAIQPRKLV
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHCCCHHHHH
DQALDRLRERLTPPAAQPVLRS
HHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]