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The map label for this gene is luxQ [H]

Identifier: 37523980

GI number: 37523980

Start: 4638075

End: 4640201

Strand: Reverse

Name: luxQ [H]

Synonym: gll4411

Alternate gene names: 37523980

Gene position: 4640201-4638075 (Counterclockwise)

Preceding gene: 37523981

Following gene: 37523979

Centisome position: 99.6

GC content: 65.54

Gene sequence:

>2127_bases
GTGGAACAGCAGCCGCTAGGCACCGCCACACCAGGGGGGAAAGCGATGGCAGGTCCGCAGGATCAACCATGCCACGACAC
GACTGCCGAATCCTCGAGTGACGAGGAAGGCATTGGCCTGTCTGAGTGCCTACGCCTGCTTATCGACGATATCGAGGATT
ACACGATCCTCACTCTCGATGGGCAAGGCACCATTGTCGGCCGCAGTGCCGGGTCCGAACGCCTGTGCGCCGGGGATCCC
CTTGGCCGGCATTTCAGTTGTCTATATGCGCACGAGGACAGCGAGCGGGGACGGCCCACACAGGACCTCGAAGAAGCGCG
CCTCCAGGGCCGCATCGCGCTGACGGGTTGGCGAGTGCGGCCCGACGGTAGCCGCTTCTGGGCCGAGGTGGTGCTCAGCG
CCCTGCGCAACCCCGATGGACAGGTGTCCGGCTATGCCATGGTCACCCACGATGTGACCGCGGGCCGGCTCGCCGAGGAG
CGGCTGGCTGGTCTCGAGCAGGAGCGAGAGCGCCTCGAACAACTGCTCAGCGGCGGCGATGCCGACCTGCCGACCCTGGC
AGCCGTCGCCCAACTCACCAACCACTCCGTGGTGATTACCGATGTCGAGCGCCGTGTCGTCTGGGTGAACGCAGGGTTCA
CCGCCCTGACGGGCTTCACTCTAGACGAAGTTCGCGGTCACAACCCGGGGGCGCTGCTGCAAGGACCACAGACCGACCCG
GCGACGGTCATGTACATGCGCGAGCGCCTCCAAAGAGGCGAGGGCTATACCGTTGAGATTCTCAACTACGGCAAAAACGG
CGATCAGTACTGGCTTGCGATCGAGGTCCAGCCGGTGCGCGATGGGACAGGCAAGCTCACCCACTTTATTGCGGTCCAAA
GAAACGTCACCGAGCAGCGGCGCGCCGGGCAGGAGCATCAGGCGTTGCTTGAGCGTGAGCAGCGCGCCCGCGAGCTGGCT
GAGCAGAACAACCGCCTCAAAGACGAGTTTCTGGCCACCTTGAGCCACGAGTTGCGCACGCCGCTCAACGGCATCCTCGG
ATTTGCCGGGTTGTTGCGCCGGGGCCGCCTCGACACCGAGACCGCCCGGCGCGCCGTCGAGATTATCGAGCGCAACGCCC
AAGCCCAGGCCCAGCTCATCGAAGACCTGCTCGACATGTCGAGCATCGCCGCGGGCACGTTCAACCTCCAGGTTCAGCCG
GTCGAGATGGCTGAGGTGGTCTCGGCGGCCGTGGCCGGCCAGCGCATAGCCGCCGAGGCCAAACGCATCCGTCTCGAGCT
GAGGCTCGATCCCCATGCCGGGCTGGTGTCGGGAGATCGCAGGCGTTTGCTGCAGGTGGTAGCCAACTTGCTCTCCAACG
CCGTCAAATTCACACCACCCGACGGCCGCATCGAAGTGTCGATGCGCTGCGTCGCCAACGCCGTTGCAATCGCCGTCGCC
GATACCGGGGTCGGCATCGGCCCCGAATTTTTGCCCTACGTCTTCGACCGCTTTCGCCAGGCGGACGGCAGCAGCACCCG
CCTGCACGGCGGTTTGGGGTTGGGCCTGTCGCTGGTGCGCCACATCGTCGAGACCCACGGCGGCTCCGTGCAGGTCCAGA
GCCTCGGCAAGAGCCAGGGGGCAACCTTTACCGTGTGCCTGCCGCTGATGCCGGTGCGCATCGGCAAAATCGAATCGCCG
CCCGATGCCGCCGAAGTGTTTCCTGCCGAGGAGTTGCCCCCGGAGGCGGCCGACTGGCTTGCGGGCTTGCGCGTGCTGGT
GGTGGACAACGACCTCCAGGCCCGCCGGGCTATTCAGCAAGTGCTCCATGGCTGCAAGGCCGAAGTGATGACTGCCGAAT
CGGCGAGTGCAGCCCTCGGACTGCTCGAACGGCTCAGGCCGGATGTACTGATCGTCGATCTGGGCGTGGGCGGCACAGAA
GGTTACGCGCTGCTTGAAGCGTTGCACGCCCAAAACCAGTTCCTACCGGTGCTCGCGCTCACCGCCTGCGCTACCGCCAG
GGACCGGGCGCGCGCTTTTTTAAGCGGGATCGATGCCTTTTTGAACAAGCCCGCCGAGCCTATCGAACTGGTCGCCCTGG
TGGCGAACCTGGGGCGCCGCTCGGAGCGCTATCGGGCCACCACTTAG

Upstream 100 bases:

>100_bases
CTATCTATCGCAAGACAGACTCCGATCGGCCCGCAATTGACTAAAAATCTTTCAGTTTCTAGAGCCCGTTTTCCTTCACT
ACCAGCTGAATAGAAGTGGG

Downstream 100 bases:

>100_bases
CAGTTCTCGCTTTCCCGCTCGCTGCTAGGCTGAAGCGGTCACCTCCGACGGCACCGGGCGATGAGTGGACGGGCGGACGA
CAATCGCCGCTATCACGACG

Product: two-component hybrid sensor and regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 708; Mature: 708

Protein sequence:

>708_residues
MEQQPLGTATPGGKAMAGPQDQPCHDTTAESSSDEEGIGLSECLRLLIDDIEDYTILTLDGQGTIVGRSAGSERLCAGDP
LGRHFSCLYAHEDSERGRPTQDLEEARLQGRIALTGWRVRPDGSRFWAEVVLSALRNPDGQVSGYAMVTHDVTAGRLAEE
RLAGLEQERERLEQLLSGGDADLPTLAAVAQLTNHSVVITDVERRVVWVNAGFTALTGFTLDEVRGHNPGALLQGPQTDP
ATVMYMRERLQRGEGYTVEILNYGKNGDQYWLAIEVQPVRDGTGKLTHFIAVQRNVTEQRRAGQEHQALLEREQRARELA
EQNNRLKDEFLATLSHELRTPLNGILGFAGLLRRGRLDTETARRAVEIIERNAQAQAQLIEDLLDMSSIAAGTFNLQVQP
VEMAEVVSAAVAGQRIAAEAKRIRLELRLDPHAGLVSGDRRRLLQVVANLLSNAVKFTPPDGRIEVSMRCVANAVAIAVA
DTGVGIGPEFLPYVFDRFRQADGSSTRLHGGLGLGLSLVRHIVETHGGSVQVQSLGKSQGATFTVCLPLMPVRIGKIESP
PDAAEVFPAEELPPEAADWLAGLRVLVVDNDLQARRAIQQVLHGCKAEVMTAESASAALGLLERLRPDVLIVDLGVGGTE
GYALLEALHAQNQFLPVLALTACATARDRARAFLSGIDAFLNKPAEPIELVALVANLGRRSERYRATT

Sequences:

>Translated_708_residues
MEQQPLGTATPGGKAMAGPQDQPCHDTTAESSSDEEGIGLSECLRLLIDDIEDYTILTLDGQGTIVGRSAGSERLCAGDP
LGRHFSCLYAHEDSERGRPTQDLEEARLQGRIALTGWRVRPDGSRFWAEVVLSALRNPDGQVSGYAMVTHDVTAGRLAEE
RLAGLEQERERLEQLLSGGDADLPTLAAVAQLTNHSVVITDVERRVVWVNAGFTALTGFTLDEVRGHNPGALLQGPQTDP
ATVMYMRERLQRGEGYTVEILNYGKNGDQYWLAIEVQPVRDGTGKLTHFIAVQRNVTEQRRAGQEHQALLEREQRARELA
EQNNRLKDEFLATLSHELRTPLNGILGFAGLLRRGRLDTETARRAVEIIERNAQAQAQLIEDLLDMSSIAAGTFNLQVQP
VEMAEVVSAAVAGQRIAAEAKRIRLELRLDPHAGLVSGDRRRLLQVVANLLSNAVKFTPPDGRIEVSMRCVANAVAIAVA
DTGVGIGPEFLPYVFDRFRQADGSSTRLHGGLGLGLSLVRHIVETHGGSVQVQSLGKSQGATFTVCLPLMPVRIGKIESP
PDAAEVFPAEELPPEAADWLAGLRVLVVDNDLQARRAIQQVLHGCKAEVMTAESASAALGLLERLRPDVLIVDLGVGGTE
GYALLEALHAQNQFLPVLALTACATARDRARAFLSGIDAFLNKPAEPIELVALVANLGRRSERYRATT
>Mature_708_residues
MEQQPLGTATPGGKAMAGPQDQPCHDTTAESSSDEEGIGLSECLRLLIDDIEDYTILTLDGQGTIVGRSAGSERLCAGDP
LGRHFSCLYAHEDSERGRPTQDLEEARLQGRIALTGWRVRPDGSRFWAEVVLSALRNPDGQVSGYAMVTHDVTAGRLAEE
RLAGLEQERERLEQLLSGGDADLPTLAAVAQLTNHSVVITDVERRVVWVNAGFTALTGFTLDEVRGHNPGALLQGPQTDP
ATVMYMRERLQRGEGYTVEILNYGKNGDQYWLAIEVQPVRDGTGKLTHFIAVQRNVTEQRRAGQEHQALLEREQRARELA
EQNNRLKDEFLATLSHELRTPLNGILGFAGLLRRGRLDTETARRAVEIIERNAQAQAQLIEDLLDMSSIAAGTFNLQVQP
VEMAEVVSAAVAGQRIAAEAKRIRLELRLDPHAGLVSGDRRRLLQVVANLLSNAVKFTPPDGRIEVSMRCVANAVAIAVA
DTGVGIGPEFLPYVFDRFRQADGSSTRLHGGLGLGLSLVRHIVETHGGSVQVQSLGKSQGATFTVCLPLMPVRIGKIESP
PDAAEVFPAEELPPEAADWLAGLRVLVVDNDLQARRAIQQVLHGCKAEVMTAESASAALGLLERLRPDVLIVDLGVGGTE
GYALLEALHAQNQFLPVLALTACATARDRARAFLSGIDAFLNKPAEPIELVALVANLGRRSERYRATT

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=390, Percent_Identity=32.3076923076923, Blast_Score=139, Evalue=7e-34,
Organism=Escherichia coli, GI1788713, Length=364, Percent_Identity=28.8461538461538, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI48994928, Length=438, Percent_Identity=28.310502283105, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI87081816, Length=381, Percent_Identity=30.1837270341207, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=35.5371900826446, Blast_Score=116, Evalue=6e-27,
Organism=Escherichia coli, GI1786600, Length=358, Percent_Identity=28.7709497206704, Blast_Score=110, Evalue=4e-25,
Organism=Escherichia coli, GI1788393, Length=231, Percent_Identity=31.1688311688312, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1786912, Length=249, Percent_Identity=32.1285140562249, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1786783, Length=246, Percent_Identity=29.2682926829268, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1788549, Length=246, Percent_Identity=29.6747967479675, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1790436, Length=250, Percent_Identity=27.6, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790346, Length=222, Percent_Identity=29.2792792792793, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787894, Length=237, Percent_Identity=28.2700421940928, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790861, Length=216, Percent_Identity=31.4814814814815, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1788279, Length=249, Percent_Identity=27.3092369477912, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789808, Length=227, Percent_Identity=32.15859030837, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87082128, Length=225, Percent_Identity=29.7777777777778, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1790300, Length=327, Percent_Identity=25.3822629969419, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789403, Length=203, Percent_Identity=28.0788177339901, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=178, Percent_Identity=33.7078651685393, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76797; Mature: 76797

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQQPLGTATPGGKAMAGPQDQPCHDTTAESSSDEEGIGLSECLRLLIDDIEDYTILTLD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEC
GQGTIVGRSAGSERLCAGDPLGRHFSCLYAHEDSERGRPTQDLEEARLQGRIALTGWRVR
CCCEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCEEEEEEEEEC
PDGSRFWAEVVLSALRNPDGQVSGYAMVTHDVTAGRLAEERLAGLEQERERLEQLLSGGD
CCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHCHHHHHHHHHHHHCCCC
ADLPTLAAVAQLTNHSVVITDVERRVVWVNAGFTALTGFTLDEVRGHNPGALLQGPQTDP
CCHHHHHHHHHHCCCCEEEEECCCEEEEEECCHHHHHCCCHHHHCCCCCCCCCCCCCCCC
ATVMYMRERLQRGEGYTVEILNYGKNGDQYWLAIEVQPVRDGTGKLTHFIAVQRNVTEQR
HHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEEEEECCCCCCCEEEEEEHHHCHHHHH
RAGQEHQALLEREQRARELAEQNNRLKDEFLATLSHELRTPLNGILGFAGLLRRGRLDTE
HCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHH
TARRAVEIIERNAQAQAQLIEDLLDMSSIAAGTFNLQVQPVEMAEVVSAAVAGQRIAAEA
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHH
KRIRLELRLDPHAGLVSGDRRRLLQVVANLLSNAVKFTPPDGRIEVSMRCVANAVAIAVA
HEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCEEECCCCCCEEEEHHHHHHHHEEEEE
DTGVGIGPEFLPYVFDRFRQADGSSTRLHGGLGLGLSLVRHIVETHGGSVQVQSLGKSQG
CCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCC
ATFTVCLPLMPVRIGKIESPPDAAEVFPAEELPPEAADWLAGLRVLVVDNDLQARRAIQQ
CEEEEEECCCCHHCCCCCCCCCHHHCCCCCCCCCHHHHHHHCCEEEEECCCHHHHHHHHH
VLHGCKAEVMTAESASAALGLLERLRPDVLIVDLGVGGTEGYALLEALHAQNQFLPVLAL
HHHCCCHHEEECCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHH
TACATARDRARAFLSGIDAFLNKPAEPIELVALVANLGRRSERYRATT
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MEQQPLGTATPGGKAMAGPQDQPCHDTTAESSSDEEGIGLSECLRLLIDDIEDYTILTLD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEC
GQGTIVGRSAGSERLCAGDPLGRHFSCLYAHEDSERGRPTQDLEEARLQGRIALTGWRVR
CCCEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCEEEEEEEEEC
PDGSRFWAEVVLSALRNPDGQVSGYAMVTHDVTAGRLAEERLAGLEQERERLEQLLSGGD
CCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHCHHHHHHHHHHHHCCCC
ADLPTLAAVAQLTNHSVVITDVERRVVWVNAGFTALTGFTLDEVRGHNPGALLQGPQTDP
CCHHHHHHHHHHCCCCEEEEECCCEEEEEECCHHHHHCCCHHHHCCCCCCCCCCCCCCCC
ATVMYMRERLQRGEGYTVEILNYGKNGDQYWLAIEVQPVRDGTGKLTHFIAVQRNVTEQR
HHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEEEEECCCCCCCEEEEEEHHHCHHHHH
RAGQEHQALLEREQRARELAEQNNRLKDEFLATLSHELRTPLNGILGFAGLLRRGRLDTE
HCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHH
TARRAVEIIERNAQAQAQLIEDLLDMSSIAAGTFNLQVQPVEMAEVVSAAVAGQRIAAEA
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHH
KRIRLELRLDPHAGLVSGDRRRLLQVVANLLSNAVKFTPPDGRIEVSMRCVANAVAIAVA
HEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCEEECCCCCCEEEEHHHHHHHHEEEEE
DTGVGIGPEFLPYVFDRFRQADGSSTRLHGGLGLGLSLVRHIVETHGGSVQVQSLGKSQG
CCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCC
ATFTVCLPLMPVRIGKIESPPDAAEVFPAEELPPEAADWLAGLRVLVVDNDLQARRAIQQ
CEEEEEECCCCHHCCCCCCCCCHHHCCCCCCCCCHHHHHHHCCEEEEECCCHHHHHHHHH
VLHGCKAEVMTAESASAALGLLERLRPDVLIVDLGVGGTEGYALLEALHAQNQFLPVLAL
HHHCCCHHEEECCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHH
TACATARDRARAFLSGIDAFLNKPAEPIELVALVANLGRRSERYRATT
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA