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The map label for this gene is dfrA [H]

Identifier: 37523204

GI number: 37523204

Start: 3832039

End: 3832935

Strand: Reverse

Name: dfrA [H]

Synonym: gll3635

Alternate gene names: 37523204

Gene position: 3832935-3832039 (Counterclockwise)

Preceding gene: 37523205

Following gene: 37523203

Centisome position: 82.27

GC content: 64.1

Gene sequence:

>897_bases
ATGATCCTGCTTACCGGCGCCACCGGTTTTATCGGTTCACACACCGCCCGAACGCTGCGCGAGCGCGGTCTTTCTGTACG
CGCTCTGGTACGCTCGGGGGCGGACACCTCTGCGCTTAAAGCTCTGGAGGTGGACCTGGTCGTGGGCCACCTGGACGACA
AAGCCTCCCTTGTCCGCGCCTGCACCGGGGTGGACGCGATCGTCCACCTGGTCGGGATCATCCGCGAACTGCCGCCGACG
GTCACCTTCGAGCGCATCCATGTCGAAGGCACCCGCAACCTGCTTGCGGCCGCGACCGAGGCCGGAGTGCGCAAATTCGT
CTACATCTCCGCCATCGGTTCTCGGCCCGACGCCATAGCCCGCTACCACCAGACCAAGTGGGCCACCGAAGCCCTGGTGC
GCTCCTCGGGACTGACCTGGGTGATCTTGCGTCCCTCGGTGGTTTTCGGTCCGGGGGACGAATTTATCAACCTGCTGGCC
AACGATCTGGTGCGCAAGCCGCCCTTTATTCCGGTCATCGGCCCCGGCACCAACAAGTTGCAACCCTTATGGGTCAAAGA
TCTGGCCGAAGTGATCGCCCGCTGCACCACCAGTTCGAGCTTCGACGGCCGCATCCTCGAAGTGGGCGGCCCCGAGCAGT
TGAGCCTGCACGAGATCTTGGCGCTGCTGGCCCGGCACCTGCGCGTGCGCAAACCCTTCGTCTCGATTCCGATCGCCCTC
GTTCAGCCCGCTGTCGCCCTGGGTAGCGCCATTGCCCCGCAACTGTTGCCCATCACCGCCGATCAACTGACGATGCTCCA
GGAGGACAACATCACCGCCGAGCGGCCCTTCAGCGGCGAATTGCGGATGCCGCTGACCGACCTGGCCACCGGCATCCGCG
AGTATCTCCAAAATTAA

Upstream 100 bases:

>100_bases
GAACACTGGAAGCGTTCGGTGTTGGCGATGCTTTTGCGCTCCTGCGGCCTCGAACCCGCCTGAAGCGCCAAATCCTTCCC
GGTGTGGCATCGTTGAATCT

Downstream 100 bases:

>100_bases
GGCAGTGCTTTATCATTGTTTAAGAAATATTCGGGTCCCCAGATGGAAGTTCTCAAGTGGGTTGTCACGATCGTCGTGCT
GTTGTTTGTGGCCATCTTCG

Product: oxidoreductase

Products: NA

Alternate protein names: DFR; Dihydrokaempferol 4-reductase [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MILLTGATGFIGSHTARTLRERGLSVRALVRSGADTSALKALEVDLVVGHLDDKASLVRACTGVDAIVHLVGIIRELPPT
VTFERIHVEGTRNLLAAATEAGVRKFVYISAIGSRPDAIARYHQTKWATEALVRSSGLTWVILRPSVVFGPGDEFINLLA
NDLVRKPPFIPVIGPGTNKLQPLWVKDLAEVIARCTTSSSFDGRILEVGGPEQLSLHEILALLARHLRVRKPFVSIPIAL
VQPAVALGSAIAPQLLPITADQLTMLQEDNITAERPFSGELRMPLTDLATGIREYLQN

Sequences:

>Translated_298_residues
MILLTGATGFIGSHTARTLRERGLSVRALVRSGADTSALKALEVDLVVGHLDDKASLVRACTGVDAIVHLVGIIRELPPT
VTFERIHVEGTRNLLAAATEAGVRKFVYISAIGSRPDAIARYHQTKWATEALVRSSGLTWVILRPSVVFGPGDEFINLLA
NDLVRKPPFIPVIGPGTNKLQPLWVKDLAEVIARCTTSSSFDGRILEVGGPEQLSLHEILALLARHLRVRKPFVSIPIAL
VQPAVALGSAIAPQLLPITADQLTMLQEDNITAERPFSGELRMPLTDLATGIREYLQN
>Mature_298_residues
MILLTGATGFIGSHTARTLRERGLSVRALVRSGADTSALKALEVDLVVGHLDDKASLVRACTGVDAIVHLVGIIRELPPT
VTFERIHVEGTRNLLAAATEAGVRKFVYISAIGSRPDAIARYHQTKWATEALVRSSGLTWVILRPSVVFGPGDEFINLLA
NDLVRKPPFIPVIGPGTNKLQPLWVKDLAEVIARCTTSSSFDGRILEVGGPEQLSLHEILALLARHLRVRKPFVSIPIAL
VQPAVALGSAIAPQLLPITADQLTMLQEDNITAERPFSGELRMPLTDLATGIREYLQN

Specific function: Unknown

COG id: COG0702

COG function: function code MG; Predicted nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydroflavonol-4-reductase family [H]

Homologues:

Organism=Homo sapiens, GI6681764, Length=228, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24667554, Length=238, Percent_Identity=26.4705882352941, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR017829
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =1.1.1.219 [H]

Molecular weight: Translated: 32244; Mature: 32244

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLTGATGFIGSHTARTLRERGLSVRALVRSGADTSALKALEVDLVVGHLDDKASLVRA
CEEEECCCCCCCHHHHHHHHHCCCCEEHHHHCCCCHHHHHHEEEEEEEECCCCHHHHHHH
CTGVDAIVHLVGIIRELPPTVTFERIHVEGTRNLLAAATEAGVRKFVYISAIGSRPDAIA
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHEEEEEECCCCCHHHH
RYHQTKWATEALVRSSGLTWVILRPSVVFGPGDEFINLLANDLVRKPPFIPVIGPGTNKL
HHHHHHHHHHHHHHCCCCEEEEEECEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCCC
QPLWVKDLAEVIARCTTSSSFDGRILEVGGPEQLSLHEILALLARHLRVRKPFVSIPIAL
CCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHCCHHH
VQPAVALGSAIAPQLLPITADQLTMLQEDNITAERPFSGELRMPLTDLATGIREYLQN
HHHHHHHHHHHCCHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MILLTGATGFIGSHTARTLRERGLSVRALVRSGADTSALKALEVDLVVGHLDDKASLVRA
CEEEECCCCCCCHHHHHHHHHCCCCEEHHHHCCCCHHHHHHEEEEEEEECCCCHHHHHHH
CTGVDAIVHLVGIIRELPPTVTFERIHVEGTRNLLAAATEAGVRKFVYISAIGSRPDAIA
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHEEEEEECCCCCHHHH
RYHQTKWATEALVRSSGLTWVILRPSVVFGPGDEFINLLANDLVRKPPFIPVIGPGTNKL
HHHHHHHHHHHHHHCCCCEEEEEECEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCCC
QPLWVKDLAEVIARCTTSSSFDGRILEVGGPEQLSLHEILALLARHLRVRKPFVSIPIAL
CCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHCCHHH
VQPAVALGSAIAPQLLPITADQLTMLQEDNITAERPFSGELRMPLTDLATGIREYLQN
HHHHHHHHHHHCCHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]