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The map label for this gene is 37523145

Identifier: 37523145

GI number: 37523145

Start: 3766134

End: 3767714

Strand: Reverse

Name: 37523145

Synonym: gll3576

Alternate gene names: NA

Gene position: 3767714-3766134 (Counterclockwise)

Preceding gene: 37523146

Following gene: 37523144

Centisome position: 80.87

GC content: 66.67

Gene sequence:

>1581_bases
ATGAGAGCGGCGTACCCACCGTCTACACCAATGCCCCGAGGTTTTGGCAAACCCCCCCGCCGTGACAATCGACCGTCCAC
GGCCATGGCCCAGGCTGCGGAGCTGCTCGATCTGGGGTTGGTTCTGCACCGGCAGGGACGCCTGGCCGAAGCGATTGTCC
GCTACGGCCAGGCGCTCGACTTTCAGGCCGATTATGTCGAGGCCCACTTTGCCCTGGGGCTTGCCCTGCAGGCGCGCGGC
GAGGGCGAAGAAGCCATTCACCATTTTCAGCGCGCCATCGAGCTGCGTAGTTACTATACCGACGCCCACTTTGCCCTGGG
GACCGCCCTGCAGGAGCAGCGGGACTTCGAAGGGGCGCTCGGTTGCTACCAGCGCACCCTCGCCATCGAACCCGAGTACG
TCAAAGCCCACAACAATCTCGGGGCGGTCCAGCGCGAACTGGGGAATCTAGATGATGCGATCGCCTCCTACCGGCGGGCG
TTGGCCCTCGAACCGGATTACCTCGAAGCCCACAACAATCTCGGGGTGGTCCTGCGCGAGCGCGGCCAATTAGAAGAAGC
CGCCCTTTGTTTTAAGCGGGCTTTTCAGCTGCAACCCGATTTTGCCGAGGCTTACTACAACCTCGGTCTGCTCCTGCACT
CCCAGCAAAAACTCGCCGAGGCAATCTCTGTCTACCGCACCGCCCTAATTATCAAAGGCGACCTGGTGGAGGCGCGCGTC
AACCTGGCCCACGCCCTGCAGGCAAGCGGCCAGGGCGACGCGGCCATCGAGGAGCACCGCCGGGCGGTTGAACTGGCACC
GGCTCTGGCTGAAGCCCACTGCGGACTGGGTAACGCCCTGCGCGACGCGGGCCGACTGGCCGAAGCCGCCGAGTGCTACG
CCGAAGCACTGCGCCTCAAACCCGATTACGCCGAGGCCCGCCACTACCTGGCGGCGGTGGGCGGCGCTCCCACTCCGGCC
ATGACCGACCCGGATTACGTGGCGGCTCTTTTTGATGAATACGCCGAGCGCTTCGACCGGCACCTGACCGGGGAACTGGC
CTACCGGGCGCCCGAACTGCTCGTGGGGGCCGTCCAAGCCGCCACTCCCCACACCGAGGGACTCTTGAACGTCCTCGATC
TCGGCTGCGGCACCGGGCTTTGCGGCCCGCTTTTGCGGCCTTTGGCCCAGCGGTTGGTGGGGATGGATCTCTCGGCCAAG
ATGATCGGCAAAGCGCGCGCGCGCGGCGTCTACGACGATCTGGCGGTGGGCGAGATGACCGAGTGGCTGGGGCGGCACCA
CGACGCCTTTGACCTGATCGTCGCGGCGGATGTGTTCACCTACGTGGGCGACCTGGCCGCCGTGTTCGCCGCCGCGGCCC
TCACCCTGGTGCCGGGGGGCGTGCTCGCTTGCTCGGTCGAAGCGGGCGAAGCGGGCTACACCCTGCTCCCCAACGGCCGC
TACGCCCATGCCCTCGATTATGTGCACAAGGAGGCCGCCGCCGCCGCTCTGGTGGCGGTGAGCACCGAGCGGGCCATTTT
GCGCACCGAGCGAGGCCGGGCGGTCGAAGGCTGGATCGTCGTGCTGCGCAGCCTGCGTTGA

Upstream 100 bases:

>100_bases
GAGAACGAAAGGCCCGTCTTCCGCCGCCTAAGCGCCATGCCGGTTGTCTAGGTGTCAGGTGGAACTTACCTGACACCTGA
CACCTGACACCTTGTGTACC

Downstream 100 bases:

>100_bases
GACGACCCTTGACAGTACCCGCAGTCGATCACTAAGCTAGGATCTGCACAATTTGCGGCCAGCTATGAAAGTCCGTGCGT
CCGTCAAACCGATATGTGAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MRAAYPPSTPMPRGFGKPPRRDNRPSTAMAQAAELLDLGLVLHRQGRLAEAIVRYGQALDFQADYVEAHFALGLALQARG
EGEEAIHHFQRAIELRSYYTDAHFALGTALQEQRDFEGALGCYQRTLAIEPEYVKAHNNLGAVQRELGNLDDAIASYRRA
LALEPDYLEAHNNLGVVLRERGQLEEAALCFKRAFQLQPDFAEAYYNLGLLLHSQQKLAEAISVYRTALIIKGDLVEARV
NLAHALQASGQGDAAIEEHRRAVELAPALAEAHCGLGNALRDAGRLAEAAECYAEALRLKPDYAEARHYLAAVGGAPTPA
MTDPDYVAALFDEYAERFDRHLTGELAYRAPELLVGAVQAATPHTEGLLNVLDLGCGTGLCGPLLRPLAQRLVGMDLSAK
MIGKARARGVYDDLAVGEMTEWLGRHHDAFDLIVAADVFTYVGDLAAVFAAAALTLVPGGVLACSVEAGEAGYTLLPNGR
YAHALDYVHKEAAAAALVAVSTERAILRTERGRAVEGWIVVLRSLR

Sequences:

>Translated_526_residues
MRAAYPPSTPMPRGFGKPPRRDNRPSTAMAQAAELLDLGLVLHRQGRLAEAIVRYGQALDFQADYVEAHFALGLALQARG
EGEEAIHHFQRAIELRSYYTDAHFALGTALQEQRDFEGALGCYQRTLAIEPEYVKAHNNLGAVQRELGNLDDAIASYRRA
LALEPDYLEAHNNLGVVLRERGQLEEAALCFKRAFQLQPDFAEAYYNLGLLLHSQQKLAEAISVYRTALIIKGDLVEARV
NLAHALQASGQGDAAIEEHRRAVELAPALAEAHCGLGNALRDAGRLAEAAECYAEALRLKPDYAEARHYLAAVGGAPTPA
MTDPDYVAALFDEYAERFDRHLTGELAYRAPELLVGAVQAATPHTEGLLNVLDLGCGTGLCGPLLRPLAQRLVGMDLSAK
MIGKARARGVYDDLAVGEMTEWLGRHHDAFDLIVAADVFTYVGDLAAVFAAAALTLVPGGVLACSVEAGEAGYTLLPNGR
YAHALDYVHKEAAAAALVAVSTERAILRTERGRAVEGWIVVLRSLR
>Mature_526_residues
MRAAYPPSTPMPRGFGKPPRRDNRPSTAMAQAAELLDLGLVLHRQGRLAEAIVRYGQALDFQADYVEAHFALGLALQARG
EGEEAIHHFQRAIELRSYYTDAHFALGTALQEQRDFEGALGCYQRTLAIEPEYVKAHNNLGAVQRELGNLDDAIASYRRA
LALEPDYLEAHNNLGVVLRERGQLEEAALCFKRAFQLQPDFAEAYYNLGLLLHSQQKLAEAISVYRTALIIKGDLVEARV
NLAHALQASGQGDAAIEEHRRAVELAPALAEAHCGLGNALRDAGRLAEAAECYAEALRLKPDYAEARHYLAAVGGAPTPA
MTDPDYVAALFDEYAERFDRHLTGELAYRAPELLVGAVQAATPHTEGLLNVLDLGCGTGLCGPLLRPLAQRLVGMDLSAK
MIGKARARGVYDDLAVGEMTEWLGRHHDAFDLIVAADVFTYVGDLAAVFAAAALTLVPGGVLACSVEAGEAGYTLLPNGR
YAHALDYVHKEAAAAALVAVSTERAILRTERGRAVEGWIVVLRSLR

Specific function: Unknown

COG id: COG4976

COG function: function code R; Predicted methyltransferase (contains TPR repeat)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 8 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=277, Percent_Identity=35.7400722021661, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI32307148, Length=277, Percent_Identity=35.7400722021661, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI301336134, Length=296, Percent_Identity=28.7162162162162, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI83415184, Length=296, Percent_Identity=28.7162162162162, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI118766330, Length=193, Percent_Identity=34.1968911917098, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI118766328, Length=193, Percent_Identity=34.1968911917098, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI22749211, Length=282, Percent_Identity=28.7234042553192, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI224809432, Length=303, Percent_Identity=23.7623762376238, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI167466177, Length=277, Percent_Identity=21.2996389891697, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI167466175, Length=277, Percent_Identity=21.2996389891697, Blast_Score=66, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI115532690, Length=309, Percent_Identity=34.3042071197411, Blast_Score=178, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI115532692, Length=309, Percent_Identity=34.3042071197411, Blast_Score=177, Evalue=9e-45,
Organism=Caenorhabditis elegans, GI25147174, Length=248, Percent_Identity=25.4032258064516, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI25146105, Length=205, Percent_Identity=26.3414634146341, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17560436, Length=209, Percent_Identity=24.8803827751196, Blast_Score=65, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6319387, Length=203, Percent_Identity=26.1083743842365, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI17647755, Length=277, Percent_Identity=35.3790613718412, Blast_Score=174, Evalue=9e-44,
Organism=Drosophila melanogaster, GI24585827, Length=277, Percent_Identity=35.3790613718412, Blast_Score=174, Evalue=9e-44,
Organism=Drosophila melanogaster, GI24585829, Length=277, Percent_Identity=35.3790613718412, Blast_Score=174, Evalue=9e-44,
Organism=Drosophila melanogaster, GI161076610, Length=341, Percent_Identity=29.0322580645161, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19920486, Length=341, Percent_Identity=29.0322580645161, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281364285, Length=340, Percent_Identity=28.2352941176471, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24581187, Length=340, Percent_Identity=28.2352941176471, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24647123, Length=192, Percent_Identity=27.6041666666667, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24656717, Length=333, Percent_Identity=24.024024024024, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI18110006, Length=333, Percent_Identity=24.024024024024, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 56988; Mature: 56988

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAAYPPSTPMPRGFGKPPRRDNRPSTAMAQAAELLDLGLVLHRQGRLAEAIVRYGQALD
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
FQADYVEAHFALGLALQARGEGEEAIHHFQRAIELRSYYTDAHFALGTALQEQRDFEGAL
CCHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GCYQRTLAIEPEYVKAHNNLGAVQRELGNLDDAIASYRRALALEPDYLEAHNNLGVVLRE
HHHHHHHCCCCHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCCCCEEECC
RGQLEEAALCFKRAFQLQPDFAEAYYNLGLLLHSQQKLAEAISVYRTALIIKGDLVEARV
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHEECHHHHHHHHHHHHHHHHEECHHHHHHH
NLAHALQASGQGDAAIEEHRRAVELAPALAEAHCGLGNALRDAGRLAEAAECYAEALRLK
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
PDYAEARHYLAAVGGAPTPAMTDPDYVAALFDEYAERFDRHLTGELAYRAPELLVGAVQA
CCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHH
ATPHTEGLLNVLDLGCGTGLCGPLLRPLAQRLVGMDLSAKMIGKARARGVYDDLAVGEMT
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHH
EWLGRHHDAFDLIVAADVFTYVGDLAAVFAAAALTLVPGGVLACSVEAGEAGYTLLPNGR
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCC
YAHALDYVHKEAAAAALVAVSTERAILRTERGRAVEGWIVVLRSLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MRAAYPPSTPMPRGFGKPPRRDNRPSTAMAQAAELLDLGLVLHRQGRLAEAIVRYGQALD
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
FQADYVEAHFALGLALQARGEGEEAIHHFQRAIELRSYYTDAHFALGTALQEQRDFEGAL
CCHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GCYQRTLAIEPEYVKAHNNLGAVQRELGNLDDAIASYRRALALEPDYLEAHNNLGVVLRE
HHHHHHHCCCCHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCCCCEEECC
RGQLEEAALCFKRAFQLQPDFAEAYYNLGLLLHSQQKLAEAISVYRTALIIKGDLVEARV
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHEECHHHHHHHHHHHHHHHHEECHHHHHHH
NLAHALQASGQGDAAIEEHRRAVELAPALAEAHCGLGNALRDAGRLAEAAECYAEALRLK
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
PDYAEARHYLAAVGGAPTPAMTDPDYVAALFDEYAERFDRHLTGELAYRAPELLVGAVQA
CCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHH
ATPHTEGLLNVLDLGCGTGLCGPLLRPLAQRLVGMDLSAKMIGKARARGVYDDLAVGEMT
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHH
EWLGRHHDAFDLIVAADVFTYVGDLAAVFAAAALTLVPGGVLACSVEAGEAGYTLLPNGR
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCC
YAHALDYVHKEAAAAALVAVSTERAILRTERGRAVEGWIVVLRSLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]