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The map label for this gene is clpB

Identifier: 37523146

GI number: 37523146

Start: 3767764

End: 3770382

Strand: Reverse

Name: clpB

Synonym: gvip486

Alternate gene names: 37523146

Gene position: 3770382-3767764 (Counterclockwise)

Preceding gene: 37523149

Following gene: 37523145

Centisome position: 80.93

GC content: 61.36

Gene sequence:

>2619_bases
ATGCAGCCCAACAACCCGAACCAATTCACCGAGAAGGCCTGGGATGCGATCGTCCGCACCACCGAGGTAGCTAAGGAGTA
CCGCCAGCAGCAGCTGGAGAGCGAACATCTTTTTAAGGCGCTCCTGGATCAAGACGGGGGGTTGGCCGGTTCGATTTTTA
CCAAGGCGGGTGTGAACCTGACGAAGCTTGGCGAGCGGGTCGAGCAGTTTATCAACCGCCAGCCCAAACTCACCAACCCC
GGCCAGAGCGTCTACCTCGGCCGCAGCCTCGACGCGCTGTTGGATCGCGCCGAGGGTTTCCGCAAAGAGTACGGCGACGA
TTTTATTTCGATCGAGCACCTGGTGCTGGCCTTCGCCAAGGACGTGCGCTTCGGACAGCAGATTCTGCGTGAATTCAGCC
TCGATGAAGCGAAGCTTAAAGCGGTCGTGGCCCAGGTGCGCGGCAACCAGAAGGTGACCAGCCAGAATCCTGAAAGCACC
TACGAGTCGCTCGATAAATACGGCCGGGATCTGACCCAATTGGCCCGCGAAGGCAAGCTCGATCCGGTGATCGGCCGCGA
CGAGGAGATTCGCCGCACCATCCAGATTCTCTCGCGCCGCACCAAAAATAACCCCGTACTGATTGGCGAACCCGGCGTGG
GCAAGACGGCCATCGCCGAGGGGCTCGCCCAGCGCATCGTCAGCGGCGATGTGCCCGAGTCGCTCCAGGGCCGCAAGCTG
ATCGCCCTCGACATGGGAGCACTGATTGCCGGATCTAAGTACCGGGGCGAATTTGAAGAACGGCTCAAGGCGGTCCTCAA
CGAGGTGACCAAGTCCGAGGGGCAGATCGTCCTTTTTATCGACGAAATTCACACGGTCGTGGGTGCGGGTGCCACCCAGG
GCGCCATGGACGCGGGCAATTTGCTCAAGCCGATGCTGGCCCGCGGCGAACTGCGCTGCATTGGGGCTACGACCCTCGAT
GAATACCGCAAATACATCGAGAAAGACGCTGCCCTGGAGCGCCGCTTCCAGCAGGTCTACGTCGATCAACCCACGGTCGA
GGACACCATTTCGATTCTGCGCGGCCTCAAAGAGCGCTACGAAGTCCACCACGGTGTGCGCATCTCCGACAGCGCCCTGG
TGGCGGCGGCGGTGCTTTCTCATCGCTACATCAGCGACCGTTTTTTGCCCGACAAAGCGATCGACTTGATGGACGAGGCG
GCGGCCAAGCTCAAGATGGAAATCACCTCCAAGCCCGAGGCCCTCGACGAGGTCGACCGCAAGATCCTGCAGCTGGAGAT
GGAGCGGCTGTCGCTGGCCAAGGAGTCCGACGCCGCCTCGCGCGATCGTCTGGAGCGGCTTGAAAAAGAACTGGCCGACC
TCAAAGAAGAGCAGCGCTCCCTCAACGCCCAGTGGCAGGCCGAGAAGGACATCATCGACCAGGTCCAGGCCGTCAAAGAA
GAAATCGACCAAGTCAACGTCCAGATCCAGCAGGCCGAGCGCGACTACGACCTCAACCGCGCCGCCGAACTGAAATACGG
CAAACTGTCCGAATTGCAAAAGCGCCTCGACGCGGCCGACAAACAACTGAGCGAGACCCAGACCAGTGGCCGGTCGCTGT
TGCGCGAGGAGGTCACCGAGGAGGACATCGCCGAAATCATCTCCAAGTGGACCGGCATCCCGGTGAGCAAACTGGTGGCG
AGCGAACGCGAGAAGCTGTTGCACCTCGAAGACGAGTTGCACAAGCGGGTGGTGGGGCAGGAAGAAGCGGTGCGGATTGT
CTCTGAAGCCATTCAGCGATCGCGCGCCGGACTTGCAGACCCGAACCGGCCGATCGCGAGCTTTATTTTTCTGGGGCCGA
CCGGCGTGGGCAAGACCGAGCTTGCCAAGGCGCTCGCGTCGTTTTTGTTCGACGACGAGAATGCCATGGTGCGCATCGAC
ATGTCCGAGTACATGGAGAAGCACAGCGTCTCGCGGCTGATTGGTGCCCCCCCAGGCTACGTGGGCTACGACGAAGGCGG
CCAGCTCACCGAGGCGGTGCGCCGCCGGCCCTACGCGGTGGTGCTCTTTGACGAGATCGAAAAAGCCCACAACGACGTCT
TCAACGTGCTGTTGCAGGTGCTCGACGACGGGCGGATCACCGATTCGCAGGGCCGCACGATCGATTTCAAAAACGCAGTG
ATCATCATGACCAGCAACATCGGCTCCGATGCGATCTTGCGCCTGGGCGGCAACGACGCCTACTACGAGCAGATGCGCGA
GGAGGTGATGCGCGCCATGCAGGTCCACTTCCGGCCGGAATTTCTCAACCGCGTCGATGACATCATCATCTTCCGCAACC
TGCGCCGCGATCAGCTCGCCGCCATCGTCAAGCTGCAGATCGCACGGCTGGAGAAGCGGCTGGCCGATCGCAAGATCACC
CTCAAGCTCAGCGAGGCCGCCATCGACTACATCGTCGAGGCGGGCTACGACCCGGTCTACGGTGCGCGCCCCCTCAAGCG
GGCCATCCAGAATGAACTGGTCAACCCGCTCGCCCGGGGATTGCTCAAGGGGGATTTTAACGACGGCGACACCATCTTTG
TCGACATCGAGAACGAAAGGCCCGTCTTCCGCCGCCTAAGCGCCATGCCGGTTGTCTAG

Upstream 100 bases:

>100_bases
GGAAATACCCACCCGGCCGGGCGGATAACCGGCTGCCGGGGGGGCAGGCGACTGCCTACAATGACCCTAGACCCCACAAG
TCATCGCACAGGAAGCCCCT

Downstream 100 bases:

>100_bases
GTGTCAGGTGGAACTTACCTGACACCTGACACCTGACACCTTGTGTACCATGAGAGCGGCGTACCCACCGTCTACACCAA
TGCCCCGAGGTTTTGGCAAA

Product: endopeptidase Clp ATP-binding chain B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 872; Mature: 872

Protein sequence:

>872_residues
MQPNNPNQFTEKAWDAIVRTTEVAKEYRQQQLESEHLFKALLDQDGGLAGSIFTKAGVNLTKLGERVEQFINRQPKLTNP
GQSVYLGRSLDALLDRAEGFRKEYGDDFISIEHLVLAFAKDVRFGQQILREFSLDEAKLKAVVAQVRGNQKVTSQNPEST
YESLDKYGRDLTQLAREGKLDPVIGRDEEIRRTIQILSRRTKNNPVLIGEPGVGKTAIAEGLAQRIVSGDVPESLQGRKL
IALDMGALIAGSKYRGEFEERLKAVLNEVTKSEGQIVLFIDEIHTVVGAGATQGAMDAGNLLKPMLARGELRCIGATTLD
EYRKYIEKDAALERRFQQVYVDQPTVEDTISILRGLKERYEVHHGVRISDSALVAAAVLSHRYISDRFLPDKAIDLMDEA
AAKLKMEITSKPEALDEVDRKILQLEMERLSLAKESDAASRDRLERLEKELADLKEEQRSLNAQWQAEKDIIDQVQAVKE
EIDQVNVQIQQAERDYDLNRAAELKYGKLSELQKRLDAADKQLSETQTSGRSLLREEVTEEDIAEIISKWTGIPVSKLVA
SEREKLLHLEDELHKRVVGQEEAVRIVSEAIQRSRAGLADPNRPIASFIFLGPTGVGKTELAKALASFLFDDENAMVRID
MSEYMEKHSVSRLIGAPPGYVGYDEGGQLTEAVRRRPYAVVLFDEIEKAHNDVFNVLLQVLDDGRITDSQGRTIDFKNAV
IIMTSNIGSDAILRLGGNDAYYEQMREEVMRAMQVHFRPEFLNRVDDIIIFRNLRRDQLAAIVKLQIARLEKRLADRKIT
LKLSEAAIDYIVEAGYDPVYGARPLKRAIQNELVNPLARGLLKGDFNDGDTIFVDIENERPVFRRLSAMPVV

Sequences:

>Translated_872_residues
MQPNNPNQFTEKAWDAIVRTTEVAKEYRQQQLESEHLFKALLDQDGGLAGSIFTKAGVNLTKLGERVEQFINRQPKLTNP
GQSVYLGRSLDALLDRAEGFRKEYGDDFISIEHLVLAFAKDVRFGQQILREFSLDEAKLKAVVAQVRGNQKVTSQNPEST
YESLDKYGRDLTQLAREGKLDPVIGRDEEIRRTIQILSRRTKNNPVLIGEPGVGKTAIAEGLAQRIVSGDVPESLQGRKL
IALDMGALIAGSKYRGEFEERLKAVLNEVTKSEGQIVLFIDEIHTVVGAGATQGAMDAGNLLKPMLARGELRCIGATTLD
EYRKYIEKDAALERRFQQVYVDQPTVEDTISILRGLKERYEVHHGVRISDSALVAAAVLSHRYISDRFLPDKAIDLMDEA
AAKLKMEITSKPEALDEVDRKILQLEMERLSLAKESDAASRDRLERLEKELADLKEEQRSLNAQWQAEKDIIDQVQAVKE
EIDQVNVQIQQAERDYDLNRAAELKYGKLSELQKRLDAADKQLSETQTSGRSLLREEVTEEDIAEIISKWTGIPVSKLVA
SEREKLLHLEDELHKRVVGQEEAVRIVSEAIQRSRAGLADPNRPIASFIFLGPTGVGKTELAKALASFLFDDENAMVRID
MSEYMEKHSVSRLIGAPPGYVGYDEGGQLTEAVRRRPYAVVLFDEIEKAHNDVFNVLLQVLDDGRITDSQGRTIDFKNAV
IIMTSNIGSDAILRLGGNDAYYEQMREEVMRAMQVHFRPEFLNRVDDIIIFRNLRRDQLAAIVKLQIARLEKRLADRKIT
LKLSEAAIDYIVEAGYDPVYGARPLKRAIQNELVNPLARGLLKGDFNDGDTIFVDIENERPVFRRLSAMPVV
>Mature_872_residues
MQPNNPNQFTEKAWDAIVRTTEVAKEYRQQQLESEHLFKALLDQDGGLAGSIFTKAGVNLTKLGERVEQFINRQPKLTNP
GQSVYLGRSLDALLDRAEGFRKEYGDDFISIEHLVLAFAKDVRFGQQILREFSLDEAKLKAVVAQVRGNQKVTSQNPEST
YESLDKYGRDLTQLAREGKLDPVIGRDEEIRRTIQILSRRTKNNPVLIGEPGVGKTAIAEGLAQRIVSGDVPESLQGRKL
IALDMGALIAGSKYRGEFEERLKAVLNEVTKSEGQIVLFIDEIHTVVGAGATQGAMDAGNLLKPMLARGELRCIGATTLD
EYRKYIEKDAALERRFQQVYVDQPTVEDTISILRGLKERYEVHHGVRISDSALVAAAVLSHRYISDRFLPDKAIDLMDEA
AAKLKMEITSKPEALDEVDRKILQLEMERLSLAKESDAASRDRLERLEKELADLKEEQRSLNAQWQAEKDIIDQVQAVKE
EIDQVNVQIQQAERDYDLNRAAELKYGKLSELQKRLDAADKQLSETQTSGRSLLREEVTEEDIAEIISKWTGIPVSKLVA
SEREKLLHLEDELHKRVVGQEEAVRIVSEAIQRSRAGLADPNRPIASFIFLGPTGVGKTELAKALASFLFDDENAMVRID
MSEYMEKHSVSRLIGAPPGYVGYDEGGQLTEAVRRRPYAVVLFDEIEKAHNDVFNVLLQVLDDGRITDSQGRTIDFKNAV
IIMTSNIGSDAILRLGGNDAYYEQMREEVMRAMQVHFRPEFLNRVDDIIIFRNLRRDQLAAIVKLQIARLEKRLADRKIT
LKLSEAAIDYIVEAGYDPVYGARPLKRAIQNELVNPLARGLLKGDFNDGDTIFVDIENERPVFRRLSAMPVV

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family

Homologues:

Organism=Homo sapiens, GI13540606, Length=319, Percent_Identity=37.6175548589342, Blast_Score=217, Evalue=4e-56,
Organism=Escherichia coli, GI1788943, Length=859, Percent_Identity=57.2759022118743, Blast_Score=991, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=403, Percent_Identity=40.1985111662531, Blast_Score=288, Evalue=1e-78,
Organism=Saccharomyces cerevisiae, GI6320464, Length=714, Percent_Identity=53.6414565826331, Blast_Score=784, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=863, Percent_Identity=43.8006952491309, Blast_Score=706, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): CLPB_GLOVI (Q7NFE9)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_926523.1
- ProteinModelPortal:   Q7NFE9
- GeneID:   2601981
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.3577
- HOGENOM:   HBG413133
- OMA:   DLNELWK
- BioCyc:   GVIO251221:GLL3577-MONOMER
- GO:   GO:0005737
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- Gene3D:   G3DSA:1.10.1780.10
- PRINTS:   PR00300
- SMART:   SM00382
- TIGRFAMs:   TIGR03346

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small

EC number: NA

Molecular weight: Translated: 98200; Mature: 98200

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00870 CLPAB_1; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPNNPNQFTEKAWDAIVRTTEVAKEYRQQQLESEHLFKALLDQDGGLAGSIFTKAGVNL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHCCCCH
TKLGERVEQFINRQPKLTNPGQSVYLGRSLDALLDRAEGFRKEYGDDFISIEHLVLAFAK
HHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
DVRFGQQILREFSLDEAKLKAVVAQVRGNQKVTSQNPESTYESLDKYGRDLTQLAREGKL
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
DPVIGRDEEIRRTIQILSRRTKNNPVLIGEPGVGKTAIAEGLAQRIVSGDVPESLQGRKL
CCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEE
IALDMGALIAGSKYRGEFEERLKAVLNEVTKSEGQIVLFIDEIHTVVGAGATQGAMDAGN
EEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCHHH
LLKPMLARGELRCIGATTLDEYRKYIEKDAALERRFQQVYVDQPTVEDTISILRGLKERY
HHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
EVHHGVRISDSALVAAAVLSHRYISDRFLPDKAIDLMDEAAAKLKMEITSKPEALDEVDR
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
KILQLEMERLSLAKESDAASRDRLERLEKELADLKEEQRSLNAQWQAEKDIIDQVQAVKE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
EIDQVNVQIQQAERDYDLNRAAELKYGKLSELQKRLDAADKQLSETQTSGRSLLREEVTE
HHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
EDIAEIISKWTGIPVSKLVASEREKLLHLEDELHKRVVGQEEAVRIVSEAIQRSRAGLAD
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCC
PNRPIASFIFLGPTGVGKTELAKALASFLFDDENAMVRIDMSEYMEKHSVSRLIGAPPGY
CCCCHHHEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCC
VGYDEGGQLTEAVRRRPYAVVLFDEIEKAHNDVFNVLLQVLDDGRITDSQGRTIDFKNAV
CCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEECCEE
IIMTSNIGSDAILRLGGNDAYYEQMREEVMRAMQVHFRPEFLNRVDDIIIFRNLRRDQLA
EEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHH
AIVKLQIARLEKRLADRKITLKLSEAAIDYIVEAGYDPVYGARPLKRAIQNELVNPLARG
HHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
LLKGDFNDGDTIFVDIENERPVFRRLSAMPVV
HHCCCCCCCCEEEEEECCCCHHHHHHHCCCCC
>Mature Secondary Structure
MQPNNPNQFTEKAWDAIVRTTEVAKEYRQQQLESEHLFKALLDQDGGLAGSIFTKAGVNL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHCCCCH
TKLGERVEQFINRQPKLTNPGQSVYLGRSLDALLDRAEGFRKEYGDDFISIEHLVLAFAK
HHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
DVRFGQQILREFSLDEAKLKAVVAQVRGNQKVTSQNPESTYESLDKYGRDLTQLAREGKL
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
DPVIGRDEEIRRTIQILSRRTKNNPVLIGEPGVGKTAIAEGLAQRIVSGDVPESLQGRKL
CCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEE
IALDMGALIAGSKYRGEFEERLKAVLNEVTKSEGQIVLFIDEIHTVVGAGATQGAMDAGN
EEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCHHH
LLKPMLARGELRCIGATTLDEYRKYIEKDAALERRFQQVYVDQPTVEDTISILRGLKERY
HHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
EVHHGVRISDSALVAAAVLSHRYISDRFLPDKAIDLMDEAAAKLKMEITSKPEALDEVDR
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
KILQLEMERLSLAKESDAASRDRLERLEKELADLKEEQRSLNAQWQAEKDIIDQVQAVKE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
EIDQVNVQIQQAERDYDLNRAAELKYGKLSELQKRLDAADKQLSETQTSGRSLLREEVTE
HHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
EDIAEIISKWTGIPVSKLVASEREKLLHLEDELHKRVVGQEEAVRIVSEAIQRSRAGLAD
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCC
PNRPIASFIFLGPTGVGKTELAKALASFLFDDENAMVRIDMSEYMEKHSVSRLIGAPPGY
CCCCHHHEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCC
VGYDEGGQLTEAVRRRPYAVVLFDEIEKAHNDVFNVLLQVLDDGRITDSQGRTIDFKNAV
CCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEECCEE
IIMTSNIGSDAILRLGGNDAYYEQMREEVMRAMQVHFRPEFLNRVDDIIIFRNLRRDQLA
EEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHH
AIVKLQIARLEKRLADRKITLKLSEAAIDYIVEAGYDPVYGARPLKRAIQNELVNPLARG
HHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
LLKGDFNDGDTIFVDIENERPVFRRLSAMPVV
HHCCCCCCCCEEEEEECCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14621292