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The map label for this gene is frdB [H]

Identifier: 37522513

GI number: 37522513

Start: 3141939

End: 3142892

Strand: Direct

Name: frdB [H]

Synonym: glr2944

Alternate gene names: 37522513

Gene position: 3141939-3142892 (Clockwise)

Preceding gene: 37522512

Following gene: 37522514

Centisome position: 67.44

GC content: 62.89

Gene sequence:

>954_bases
ATGGAAATTACTATTCGCATCCGCCGCCAGGCCGAATCGGGTTCGCCGGATTACAAAAGCTATGGGCTCGATGTCGATCC
CGGCACCACGGTGCTCGACGCCCTGATGCGCATCAAGGGCGAGATCGACGGCACCCTTGCCTTTCGCAAAAATTGCCGCA
ACGCGATTTGCGGCAGTTGCGCGATGCGCATCAACGGCCGCTCGGCCCTCGCCTGCGCAAACCGCATCCGCGATGTGGCG
GACGCCCGCGGCGAGATATTGATTCAACCGATGGGCAATATGCCGGTGATTAAGGATCTGGTGGTCGATATGACCAGTTT
CTGGAAGCACCTCGACCAGGTGGATCCCTACGTGAGCACGGCCGCTCGCCGCCCGCCCGAAAAAGAATTCCTGCAGACGC
CCGAGCAGCGCGCCGCCGTCGAGCAGGCGGGCAACTGCATCCTCTGCGGCGCCTGCTACTCCGAGTGCAACTCCCGCGAG
GTCAACCCCAATTTTGTTGGTCCCCACGCCTTGGCCAAGGCCCAGCGGGTGATGGCCGACAACCGCGACGACCGGACCGC
CCAGCGCCACGCGCTGTACAACCAACCGGAATTTGCCTGGGGCTGCACCCGCTGCTTCTACTGCAACGAGGTCTGCCCGA
TGGGCGTCCAGCCCCTCGATCAAATCCAGAAGATCCGCCACGAACTGCTCACCGACAAGGCGGCTCAGCCCAACACCGCC
ATGCGCCACCGCCGGGTGATGGTACGCCAGATCAAAGAATCCGGCTGGCTGGACGAAGCCAGCTTCGCCCTGCAGGTGGT
CGGTCGCGACTTTAAGGGGCTGTGGAACCTGGTGCCCCTCGGCGTGCGCATGGCCGCCAAGGGCAAGATGCCCCTGCGCC
ACCGGCCCATCGAGAATTGTGCGCAAGTGCGCGACTTGATCGAGGAAATCCAGAAAGAAGACGCCCAATCATGA

Upstream 100 bases:

>100_bases
ACAAACTGTTCATTTTGAACTAAAATTCGCCCCAGGCGTTCCGGCGAGCGGATATGGTAGTGTTGGTGGCTACGTCCAGC
CACACTGCCGGTATTTTTAG

Downstream 100 bases:

>100_bases
TCGCCACTCCCCTCAAATATGCCTACTATCCCGGCTGTGTCGCCCGCGGCGCCTGTCGGGAACTGTACACTTCCACCGCC
TTGATCACCGAAGCCCTGGG

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MEITIRIRRQAESGSPDYKSYGLDVDPGTTVLDALMRIKGEIDGTLAFRKNCRNAICGSCAMRINGRSALACANRIRDVA
DARGEILIQPMGNMPVIKDLVVDMTSFWKHLDQVDPYVSTAARRPPEKEFLQTPEQRAAVEQAGNCILCGACYSECNSRE
VNPNFVGPHALAKAQRVMADNRDDRTAQRHALYNQPEFAWGCTRCFYCNEVCPMGVQPLDQIQKIRHELLTDKAAQPNTA
MRHRRVMVRQIKESGWLDEASFALQVVGRDFKGLWNLVPLGVRMAAKGKMPLRHRPIENCAQVRDLIEEIQKEDAQS

Sequences:

>Translated_317_residues
MEITIRIRRQAESGSPDYKSYGLDVDPGTTVLDALMRIKGEIDGTLAFRKNCRNAICGSCAMRINGRSALACANRIRDVA
DARGEILIQPMGNMPVIKDLVVDMTSFWKHLDQVDPYVSTAARRPPEKEFLQTPEQRAAVEQAGNCILCGACYSECNSRE
VNPNFVGPHALAKAQRVMADNRDDRTAQRHALYNQPEFAWGCTRCFYCNEVCPMGVQPLDQIQKIRHELLTDKAAQPNTA
MRHRRVMVRQIKESGWLDEASFALQVVGRDFKGLWNLVPLGVRMAAKGKMPLRHRPIENCAQVRDLIEEIQKEDAQS
>Mature_317_residues
MEITIRIRRQAESGSPDYKSYGLDVDPGTTVLDALMRIKGEIDGTLAFRKNCRNAICGSCAMRINGRSALACANRIRDVA
DARGEILIQPMGNMPVIKDLVVDMTSFWKHLDQVDPYVSTAARRPPEKEFLQTPEQRAAVEQAGNCILCGACYSECNSRE
VNPNFVGPHALAKAQRVMADNRDDRTAQRHALYNQPEFAWGCTRCFYCNEVCPMGVQPLDQIQKIRHELLTDKAAQPNTA
MRHRRVMVRQIKESGWLDEASFALQVVGRDFKGLWNLVPLGVRMAAKGKMPLRHRPIENCAQVRDLIEEIQKEDAQS

Specific function: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth [H]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=221, Percent_Identity=37.5565610859729, Blast_Score=152, Evalue=5e-37,
Organism=Escherichia coli, GI1790596, Length=218, Percent_Identity=38.5321100917431, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786943, Length=237, Percent_Identity=35.4430379746835, Blast_Score=154, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17533915, Length=238, Percent_Identity=34.453781512605, Blast_Score=141, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6322987, Length=219, Percent_Identity=37.4429223744292, Blast_Score=150, Evalue=2e-37,
Organism=Drosophila melanogaster, GI17137106, Length=237, Percent_Identity=33.7552742616034, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI24643156, Length=231, Percent_Identity=34.1991341991342, Blast_Score=138, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 35685; Mature: 35685

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEITIRIRRQAESGSPDYKSYGLDVDPGTTVLDALMRIKGEIDGTLAFRKNCRNAICGSC
CEEEEEEEECCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AMRINGRSALACANRIRDVADARGEILIQPMGNMPVIKDLVVDMTSFWKHLDQVDPYVST
HEEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCHHHHH
AARRPPEKEFLQTPEQRAAVEQAGNCILCGACYSECNSREVNPNFVGPHALAKAQRVMAD
HHCCCCHHHHHCCCHHHHHHHHCCCEEEEHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
NRDDRTAQRHALYNQPEFAWGCTRCFYCNEVCPMGVQPLDQIQKIRHELLTDKAAQPNTA
CCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHH
MRHRRVMVRQIKESGWLDEASFALQVVGRDFKGLWNLVPLGVRMAAKGKMPLRHRPIENC
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
AQVRDLIEEIQKEDAQS
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEITIRIRRQAESGSPDYKSYGLDVDPGTTVLDALMRIKGEIDGTLAFRKNCRNAICGSC
CEEEEEEEECCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AMRINGRSALACANRIRDVADARGEILIQPMGNMPVIKDLVVDMTSFWKHLDQVDPYVST
HEEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCHHHHH
AARRPPEKEFLQTPEQRAAVEQAGNCILCGACYSECNSREVNPNFVGPHALAKAQRVMAD
HHCCCCHHHHHCCCHHHHHHHHCCCEEEEHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
NRDDRTAQRHALYNQPEFAWGCTRCFYCNEVCPMGVQPLDQIQKIRHELLTDKAAQPNTA
CCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHH
MRHRRVMVRQIKESGWLDEASFALQVVGRDFKGLWNLVPLGVRMAAKGKMPLRHRPIENC
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
AQVRDLIEEIQKEDAQS
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3308458 [H]