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The map label for this gene is yafV [C]

Identifier: 37522512

GI number: 37522512

Start: 3141011

End: 3141823

Strand: Direct

Name: yafV [C]

Synonym: glr2943

Alternate gene names: 37522512

Gene position: 3141011-3141823 (Clockwise)

Preceding gene: 37522511

Following gene: 37522513

Centisome position: 67.42

GC content: 65.81

Gene sequence:

>813_bases
GTGATAGAAAGCTACCTGGCCGCCGCTATCCAGATGACCAGCACCGCCGACATCGAGGCCAACCTCGACCAGGCCTATGC
GCTGATTGGCATCGCGGTGCGCCGCGGCGCCCGCCTGGTCAGCCTGCCCGAGAACTTTGCCTTTCTGGGACTGGAGGCTG
AGAAACTCGCCCTCGCCCCGCGCATCGCCGAGATGAGCGAAAAATTTCTTGTCTCCGCCGCGCGCGACTGGGCGGTGACG
CTGCTGGGCGGCGGCTACCCGGTGCTCGCCGAGCAGACGGCCAAGTGCTACAACACAGCCCTGCTCGTGGGTCCCGAGGG
TCAGGAGTTGGGCCGCTACCGCAAATTGCACCTGTTCGACGTCAACCTGCCCGACGGCAACACTTACCACGAGTCCGACT
CGATCGTGCCCGGCAAAGACCTGGTGGTGGTGCGCAGCGACACCCTCGGCAATCTGGGTCTATCGGTCTGCTACGACCTG
CGCTTTCCGGAACTCTACCGGGCCCTCTCGGCGGCGGGGGCGGAAGTCCTGCTGGTGCCCTCGGCCTTTACCGCCTTCAC
CGGCAAGGACCACTGGCGGGTGCTCCTGCAGGCGCGGGCGATCGAAAATACCTGCTACGTGATCGCCGCCGCCCAGACCG
GCGAGCACTATCCGCGTCGGCAAACCTACGGCCACGCGATGATCGTCGATCCGTGGGGCAACGTGCTCTCCGACGCCGGG
GACACCACCGGCATCGCCATCGGCGAAATCAACCCCATGCGTCTGGAGGCGGTGCGCCGCCAATTGCCCGTGCTGCAACA
CCGGCAACTTTGA

Upstream 100 bases:

>100_bases
AGCTAAAGAGCGCCCGATTATCAAAGTCGACCGCCTGGAATTGCTCGGCTCCAAGCGCGACAGCACCGGCGAGGCACCGA
GCATGGACGAGGATTTTTAA

Downstream 100 bases:

>100_bases
TCCCGGGCCGCCATTACAAACTGTTCATTTTGAACTAAAATTCGCCCCAGGCGTTCCGGCGAGCGGATATGGTAGTGTTG
GTGGCTACGTCCAGCCACAC

Product: nitrilase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MIESYLAAAIQMTSTADIEANLDQAYALIGIAVRRGARLVSLPENFAFLGLEAEKLALAPRIAEMSEKFLVSAARDWAVT
LLGGGYPVLAEQTAKCYNTALLVGPEGQELGRYRKLHLFDVNLPDGNTYHESDSIVPGKDLVVVRSDTLGNLGLSVCYDL
RFPELYRALSAAGAEVLLVPSAFTAFTGKDHWRVLLQARAIENTCYVIAAAQTGEHYPRRQTYGHAMIVDPWGNVLSDAG
DTTGIAIGEINPMRLEAVRRQLPVLQHRQL

Sequences:

>Translated_270_residues
MIESYLAAAIQMTSTADIEANLDQAYALIGIAVRRGARLVSLPENFAFLGLEAEKLALAPRIAEMSEKFLVSAARDWAVT
LLGGGYPVLAEQTAKCYNTALLVGPEGQELGRYRKLHLFDVNLPDGNTYHESDSIVPGKDLVVVRSDTLGNLGLSVCYDL
RFPELYRALSAAGAEVLLVPSAFTAFTGKDHWRVLLQARAIENTCYVIAAAQTGEHYPRRQTYGHAMIVDPWGNVLSDAG
DTTGIAIGEINPMRLEAVRRQLPVLQHRQL
>Mature_270_residues
MIESYLAAAIQMTSTADIEANLDQAYALIGIAVRRGARLVSLPENFAFLGLEAEKLALAPRIAEMSEKFLVSAARDWAVT
LLGGGYPVLAEQTAKCYNTALLVGPEGQELGRYRKLHLFDVNLPDGNTYHESDSIVPGKDLVVVRSDTLGNLGLSVCYDL
RFPELYRALSAAGAEVLLVPSAFTAFTGKDHWRVLLQARAIENTCYVIAAAQTGEHYPRRQTYGHAMIVDPWGNVLSDAG
DTTGIAIGEINPMRLEAVRRQLPVLQHRQL

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI297632348, Length=269, Percent_Identity=44.2379182156134, Blast_Score=214, Evalue=5e-56,
Organism=Homo sapiens, GI5031947, Length=273, Percent_Identity=43.956043956044, Blast_Score=214, Evalue=5e-56,
Organism=Homo sapiens, GI297632350, Length=269, Percent_Identity=44.2379182156134, Blast_Score=214, Evalue=6e-56,
Organism=Homo sapiens, GI9910460, Length=268, Percent_Identity=33.5820895522388, Blast_Score=168, Evalue=4e-42,
Organism=Homo sapiens, GI297632346, Length=196, Percent_Identity=41.3265306122449, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17556280, Length=268, Percent_Identity=40.2985074626866, Blast_Score=197, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6323383, Length=270, Percent_Identity=32.962962962963, Blast_Score=173, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6322335, Length=294, Percent_Identity=32.9931972789116, Blast_Score=166, Evalue=3e-42,
Organism=Drosophila melanogaster, GI17933642, Length=273, Percent_Identity=38.8278388278388, Blast_Score=175, Evalue=3e-44,
Organism=Drosophila melanogaster, GI21355835, Length=265, Percent_Identity=32.4528301886792, Blast_Score=153, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 29496; Mature: 29496

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIESYLAAAIQMTSTADIEANLDQAYALIGIAVRRGARLVSLPENFAFLGLEAEKLALAP
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCEEEEECCHHHHHHHH
RIAEMSEKFLVSAARDWAVTLLGGGYPVLAEQTAKCYNTALLVGPEGQELGRYRKLHLFD
HHHHHHHHHHHHHCCCEEEEEECCCEEEHHHHHHHHHCEEEEECCCCHHHCCEEEEEEEE
VNLPDGNTYHESDSIVPGKDLVVVRSDTLGNLGLSVCYDLRFPELYRALSAAGAEVLLVP
EECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHCCCEEEEEC
SAFTAFTGKDHWRVLLQARAIENTCYVIAAAQTGEHYPRRQTYGHAMIVDPWGNVLSDAG
CCCEECCCCHHHEEEEEHHHCCCEEEEEEEECCCCCCCCCCCCCCEEEECCCHHHHHCCC
DTTGIAIGEINPMRLEAVRRQLPVLQHRQL
CCCCEEEECCCHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MIESYLAAAIQMTSTADIEANLDQAYALIGIAVRRGARLVSLPENFAFLGLEAEKLALAP
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCEEEEECCHHHHHHHH
RIAEMSEKFLVSAARDWAVTLLGGGYPVLAEQTAKCYNTALLVGPEGQELGRYRKLHLFD
HHHHHHHHHHHHHCCCEEEEEECCCEEEHHHHHHHHHCEEEEECCCCHHHCCEEEEEEEE
VNLPDGNTYHESDSIVPGKDLVVVRSDTLGNLGLSVCYDLRFPELYRALSAAGAEVLLVP
EECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHCCCEEEEEC
SAFTAFTGKDHWRVLLQARAIENTCYVIAAAQTGEHYPRRQTYGHAMIVDPWGNVLSDAG
CCCEECCCCHHHEEEEEHHHCCCEEEEEEEECCCCCCCCCCCCCCEEEECCCHHHHHCCC
DTTGIAIGEINPMRLEAVRRQLPVLQHRQL
CCCCEEEECCCHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]