Click here to switch to the map view.

The map label for this gene is pqqL [C]

Identifier: 37522155

GI number: 37522155

Start: 2738667

End: 2739941

Strand: Reverse

Name: pqqL [C]

Synonym: gll2586

Alternate gene names: 37522155

Gene position: 2739941-2738667 (Counterclockwise)

Preceding gene: 37522157

Following gene: 37522154

Centisome position: 58.81

GC content: 65.8

Gene sequence:

>1275_bases
ATGATAGCGACCATACCTGCAAGTACCGAAGCTTTCGCGGGCCGTATCCGCACCCTGCCCAACGGGCTGACTTTGATCGT
TCAGCAGATCCCGACTGCCGCCGCCGTCACCTGCGATATCTGGGTGCGCACGGGGGCCCGTACCGAACCGCTCCAGTTGT
CGGGCGTCTCGCATTTTCTCGAACACATGATCTTCAAGGGCACCGAGAAAGTCGGTCCCGGCGTCTTCGACAGCGAAATC
GAAAGCCGCGGCGGGGTGACCAACGCCGCCACCAGTCAGGATTACACCCACTACTTCATCACCGTCGCCAACGAGCACTA
CGAAGCGTCGCTTCCCTATCTGGCGGAACTGGTCAACGCCGCGGCGATCCCGCCTGCGGAATACGAGCGCGAGCGGCTGG
TGGTGCTCGAAGAGATCCGCCGCAGCAACGACAGTCCCGACCGCCGGGCCTTCGAGATCCTCACCCGCACCATGTACCCC
GAGCATCCCTACAGCCGGCCGGTCCTGGGCACCGCCGAGAGCCTGCTCGCGATGACGGCCGATCAGATGCGTACCTACCA
CCGCGAGCGCTACCGGCCCGCCAACACTACTGTTGTGATCGTGGGCGGCGTACCGGAGGAGCAGATGCTGGCCGCCGCCG
AGGCATTGTTTGCACCCCTGGGCGAAGGGCCGACAGGCGAAGTGCCGACGGTGCCGCATCCGGCCGCCCCCACGCCGGGG
GTATCCACCCACACCCTGGCCCGCCTGGAGCAGCCGCGCCTGATGCTCGCCTGGTTGGGTGCTGCGATCGAGCAGATCGA
AGATGCGATCGCCCTCGACGTGCTCGCCACCGTGCTCAGCGAGGGGCGCACCTCCCGGCTGGTGCGCTCGCTGCGCGAAG
AAAAAGGCTGGGCGCGCTCGGTGAACGCCTACTTTATGCCCCAAAAGCACCCGGGCCTGTTCATTGTCTCTGCCCAGGCC
GACGCCGAATGGCTCGAACCCATCGAGGCCGAAGTGCGCGCTCAAGTACGCGCCCTGGTTGACGAACCGGTGCCGGACGG
CGAATTCAACCGCGCCCTGCGCATCTTGCGCAACGACTTTATCTTCAGCACCGAGGCCCCGGCCCAGTTGGCGAGTCTCT
ACGGTTACTACAGCACCGTGGCGAAACTCGAGCTGGCCCTCGCCTATCCCGAGTTGCTGCAGCGCGTTCAACCGGCCGAC
CTGCAGCGCGTCGCCCGCCGCTATCTCGAGCCTGATCGGGCGGTGGTCCTGCGGCTTGTGCCCGAAACCCCCTGA

Upstream 100 bases:

>100_bases
CCTCGGCTGGTCCCCGATTGATCAATGTTCTTCCAAGCGTAACAGCGGCTTGCAGCCCGACCTTCCCCTGATCCGCGACA
AGGAATGCCATCATGAAGAA

Downstream 100 bases:

>100_bases
GGATCTATGTTCCGTACCACGCTTGCCAGCGGCCTTCGCGTCCTTGTGCTCAACAACCCGGCCGTCGATATTGTGAGCGC
CCGCTTCTTCCTGCGGGTCG

Product: processing protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MIATIPASTEAFAGRIRTLPNGLTLIVQQIPTAAAVTCDIWVRTGARTEPLQLSGVSHFLEHMIFKGTEKVGPGVFDSEI
ESRGGVTNAATSQDYTHYFITVANEHYEASLPYLAELVNAAAIPPAEYERERLVVLEEIRRSNDSPDRRAFEILTRTMYP
EHPYSRPVLGTAESLLAMTADQMRTYHRERYRPANTTVVIVGGVPEEQMLAAAEALFAPLGEGPTGEVPTVPHPAAPTPG
VSTHTLARLEQPRLMLAWLGAAIEQIEDAIALDVLATVLSEGRTSRLVRSLREEKGWARSVNAYFMPQKHPGLFIVSAQA
DAEWLEPIEAEVRAQVRALVDEPVPDGEFNRALRILRNDFIFSTEAPAQLASLYGYYSTVAKLELALAYPELLQRVQPAD
LQRVARRYLEPDRAVVLRLVPETP

Sequences:

>Translated_424_residues
MIATIPASTEAFAGRIRTLPNGLTLIVQQIPTAAAVTCDIWVRTGARTEPLQLSGVSHFLEHMIFKGTEKVGPGVFDSEI
ESRGGVTNAATSQDYTHYFITVANEHYEASLPYLAELVNAAAIPPAEYERERLVVLEEIRRSNDSPDRRAFEILTRTMYP
EHPYSRPVLGTAESLLAMTADQMRTYHRERYRPANTTVVIVGGVPEEQMLAAAEALFAPLGEGPTGEVPTVPHPAAPTPG
VSTHTLARLEQPRLMLAWLGAAIEQIEDAIALDVLATVLSEGRTSRLVRSLREEKGWARSVNAYFMPQKHPGLFIVSAQA
DAEWLEPIEAEVRAQVRALVDEPVPDGEFNRALRILRNDFIFSTEAPAQLASLYGYYSTVAKLELALAYPELLQRVQPAD
LQRVARRYLEPDRAVVLRLVPETP
>Mature_424_residues
MIATIPASTEAFAGRIRTLPNGLTLIVQQIPTAAAVTCDIWVRTGARTEPLQLSGVSHFLEHMIFKGTEKVGPGVFDSEI
ESRGGVTNAATSQDYTHYFITVANEHYEASLPYLAELVNAAAIPPAEYERERLVVLEEIRRSNDSPDRRAFEILTRTMYP
EHPYSRPVLGTAESLLAMTADQMRTYHRERYRPANTTVVIVGGVPEEQMLAAAEALFAPLGEGPTGEVPTVPHPAAPTPG
VSTHTLARLEQPRLMLAWLGAAIEQIEDAIALDVLATVLSEGRTSRLVRSLREEKGWARSVNAYFMPQKHPGLFIVSAQA
DAEWLEPIEAEVRAQVRALVDEPVPDGEFNRALRILRNDFIFSTEAPAQLASLYGYYSTVAKLELALAYPELLQRVQPAD
LQRVARRYLEPDRAVVLRLVPETP

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=271, Percent_Identity=27.6752767527675, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI46593007, Length=200, Percent_Identity=26, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI24308013, Length=443, Percent_Identity=23.7020316027088, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI155969707, Length=239, Percent_Identity=24.2677824267782, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1787770, Length=249, Percent_Identity=28.9156626506024, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI2367164, Length=246, Percent_Identity=25.609756097561, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17553678, Length=326, Percent_Identity=26.9938650306748, Blast_Score=111, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI71999683, Length=318, Percent_Identity=25.1572327044025, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25146566, Length=195, Percent_Identity=25.1282051282051, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994338, Length=195, Percent_Identity=25.1282051282051, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25146563, Length=195, Percent_Identity=25.1282051282051, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32566665, Length=209, Percent_Identity=24.4019138755981, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI72001443, Length=192, Percent_Identity=24.4791666666667, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323192, Length=240, Percent_Identity=28.75, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6323421, Length=196, Percent_Identity=25, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325379, Length=214, Percent_Identity=26.1682242990654, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324474, Length=292, Percent_Identity=25.6849315068493, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6321813, Length=422, Percent_Identity=23.4597156398104, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21357875, Length=413, Percent_Identity=24.2130750605327, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24646943, Length=413, Percent_Identity=24.2130750605327, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24641429, Length=212, Percent_Identity=26.4150943396226, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221513245, Length=227, Percent_Identity=25.9911894273128, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24667786, Length=202, Percent_Identity=25.7425742574257, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 46882; Mature: 46882

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIATIPASTEAFAGRIRTLPNGLTLIVQQIPTAAAVTCDIWVRTGARTEPLQLSGVSHFL
CEEECCCCHHHHHHHHHCCCCHHHHHHHHCCCHHEEEEEEEEECCCCCCCEECCCHHHHH
EHMIFKGTEKVGPGVFDSEIESRGGVTNAATSQDYTHYFITVANEHYEASLPYLAELVNA
HHHHHCCCHHCCCCCCHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHH
AAIPPAEYERERLVVLEEIRRSNDSPDRRAFEILTRTMYPEHPYSRPVLGTAESLLAMTA
HCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
DQMRTYHRERYRPANTTVVIVGGVPEEQMLAAAEALFAPLGEGPTGEVPTVPHPAAPTPG
HHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
VSTHTLARLEQPRLMLAWLGAAIEQIEDAIALDVLATVLSEGRTSRLVRSLREEKGWARS
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHCC
VNAYFMPQKHPGLFIVSAQADAEWLEPIEAEVRAQVRALVDEPVPDGEFNRALRILRNDF
CCEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
IFSTEAPAQLASLYGYYSTVAKLELALAYPELLQRVQPADLQRVARRYLEPDRAVVLRLV
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEC
PETP
CCCC
>Mature Secondary Structure
MIATIPASTEAFAGRIRTLPNGLTLIVQQIPTAAAVTCDIWVRTGARTEPLQLSGVSHFL
CEEECCCCHHHHHHHHHCCCCHHHHHHHHCCCHHEEEEEEEEECCCCCCCEECCCHHHHH
EHMIFKGTEKVGPGVFDSEIESRGGVTNAATSQDYTHYFITVANEHYEASLPYLAELVNA
HHHHHCCCHHCCCCCCHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHH
AAIPPAEYERERLVVLEEIRRSNDSPDRRAFEILTRTMYPEHPYSRPVLGTAESLLAMTA
HCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
DQMRTYHRERYRPANTTVVIVGGVPEEQMLAAAEALFAPLGEGPTGEVPTVPHPAAPTPG
HHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
VSTHTLARLEQPRLMLAWLGAAIEQIEDAIALDVLATVLSEGRTSRLVRSLREEKGWARS
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHCC
VNAYFMPQKHPGLFIVSAQADAEWLEPIEAEVRAQVRALVDEPVPDGEFNRALRILRNDF
CCEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
IFSTEAPAQLASLYGYYSTVAKLELALAYPELLQRVQPADLQRVARRYLEPDRAVVLRLV
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEC
PETP
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA