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The map label for this gene is pqqL [C]

Identifier: 37522154

GI number: 37522154

Start: 2737419

End: 2738660

Strand: Reverse

Name: pqqL [C]

Synonym: gll2585

Alternate gene names: 37522154

Gene position: 2738660-2737419 (Counterclockwise)

Preceding gene: 37522155

Following gene: 37522152

Centisome position: 58.78

GC content: 63.37

Gene sequence:

>1242_bases
ATGTTCCGTACCACGCTTGCCAGCGGCCTTCGCGTCCTTGTGCTCAACAACCCGGCCGTCGATATTGTGAGCGCCCGCTT
CTTCCTGCGGGTCGACAGCCGCACAGATACCCCGCCGGGGCTGGCCCACCTGGTCAGTGCCGTGCTGACCAAGGGTACCG
AGGCGCGCGATTCGATGGCTATAGCCCAGATTGTCGAATCGCTCGGGGCGATGCTGGGTGCCGACAGTACCCCCGATTAT
CTGCAAATTGCCCTCAAAAGCCTGGGCGAAGACTTTCCGACCCTGCTTGCCCTTGCCGCCGAACTGTTGCAGCGGGCGAC
CTTTCCTGCCGAGCAAATCGAAATCGAACGAAAAGCGACTCTGCAAGCGATCCGTTCCCAGCAGGAGCGGCCCTTCACCG
TCGCCTACAACCAGTTTCGCGCGGCACTCTACGGCAACTCCCCCTACGCCTATCCGGAGTTGGGCACCGAGGAGAGTGTG
TTGGCCCTGCGGCGCGAGGATCTGCTGAATTTTTACCGCGCCCATTTTCGGCCGGACAACGCCGTGTTCGTGGCCGTCGG
GCCGCTCGAGCCAGAGGCGGTTGTCCGCTTGCTCGAAGAGCATCTGGGCGGCTGGAGTGTACCTGAGACACCACTGTTGC
GTACGGCGCTCCTAAAGCCGACCGATGCTTTTCCCACCGCTACCCTGCGCACGGTGCAACCCACCCAGCAGAGCACAGTC
CTGGTGGGCTATCCTGCAGCACCAATCCACTCGGAAGATTTTGCGGCCCTCAAACTGATCGGCACCTACCTCGGCAGCGG
GCTTTCCAGTCGCCTGTTCACCGAACTGCGCGAAAAGCGCGGCCTTGCCTACGAAGTCTCCGCCTTCTATCCGACCCGGG
CCTCCACTTCCCACTTCGTCGCCTACATCGGTACCGCCCCCGAGAACGCCCGCACCTGCGAAGCGGGCCTGCGCACCGAA
GTCGAGCGCCTGGCGAGCACGCCGCTCGGCGACTCCGAACTGCGCACGGCCAAAAACAAGCTGCTGGGCCAGTACGCCCT
CGGCAAGCAGACCAACAGCCAGGTGGCTCAGCTGCTGGGCTGGTACGAGATTCTGGGCGTCGGTGCCGACTTCGACCGCG
AGTACACCCGCACCGTCGAGCAATTGACGAGTGCCGACTTGCTGGCGGTGGCCGAGCGCACCTTCAAAGCACCCATCGTC
TCGCTGGTGGGGCCTGAGGACGTGCTTGCAACGGTCTTCTAA

Upstream 100 bases:

>100_bases
GCGCGTTCAACCGGCCGACCTGCAGCGCGTCGCCCGCCGCTATCTCGAGCCTGATCGGGCGGTGGTCCTGCGGCTTGTGC
CCGAAACCCCCTGAGGATCT

Downstream 100 bases:

>100_bases
AACGAGCGCTGCGAGCCGACAATATCGTCGTAGGCCACGGCGATGGCGCTGTAGATAATCGGAAACGCGACCAGCAGCCC
GAGCCCCAGGGGAATCGCCC

Product: processing protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MFRTTLASGLRVLVLNNPAVDIVSARFFLRVDSRTDTPPGLAHLVSAVLTKGTEARDSMAIAQIVESLGAMLGADSTPDY
LQIALKSLGEDFPTLLALAAELLQRATFPAEQIEIERKATLQAIRSQQERPFTVAYNQFRAALYGNSPYAYPELGTEESV
LALRREDLLNFYRAHFRPDNAVFVAVGPLEPEAVVRLLEEHLGGWSVPETPLLRTALLKPTDAFPTATLRTVQPTQQSTV
LVGYPAAPIHSEDFAALKLIGTYLGSGLSSRLFTELREKRGLAYEVSAFYPTRASTSHFVAYIGTAPENARTCEAGLRTE
VERLASTPLGDSELRTAKNKLLGQYALGKQTNSQVAQLLGWYEILGVGADFDREYTRTVEQLTSADLLAVAERTFKAPIV
SLVGPEDVLATVF

Sequences:

>Translated_413_residues
MFRTTLASGLRVLVLNNPAVDIVSARFFLRVDSRTDTPPGLAHLVSAVLTKGTEARDSMAIAQIVESLGAMLGADSTPDY
LQIALKSLGEDFPTLLALAAELLQRATFPAEQIEIERKATLQAIRSQQERPFTVAYNQFRAALYGNSPYAYPELGTEESV
LALRREDLLNFYRAHFRPDNAVFVAVGPLEPEAVVRLLEEHLGGWSVPETPLLRTALLKPTDAFPTATLRTVQPTQQSTV
LVGYPAAPIHSEDFAALKLIGTYLGSGLSSRLFTELREKRGLAYEVSAFYPTRASTSHFVAYIGTAPENARTCEAGLRTE
VERLASTPLGDSELRTAKNKLLGQYALGKQTNSQVAQLLGWYEILGVGADFDREYTRTVEQLTSADLLAVAERTFKAPIV
SLVGPEDVLATVF
>Mature_413_residues
MFRTTLASGLRVLVLNNPAVDIVSARFFLRVDSRTDTPPGLAHLVSAVLTKGTEARDSMAIAQIVESLGAMLGADSTPDY
LQIALKSLGEDFPTLLALAAELLQRATFPAEQIEIERKATLQAIRSQQERPFTVAYNQFRAALYGNSPYAYPELGTEESV
LALRREDLLNFYRAHFRPDNAVFVAVGPLEPEAVVRLLEEHLGGWSVPETPLLRTALLKPTDAFPTATLRTVQPTQQSTV
LVGYPAAPIHSEDFAALKLIGTYLGSGLSSRLFTELREKRGLAYEVSAFYPTRASTSHFVAYIGTAPENARTCEAGLRTE
VERLASTPLGDSELRTAKNKLLGQYALGKQTNSQVAQLLGWYEILGVGADFDREYTRTVEQLTSADLLAVAERTFKAPIV
SLVGPEDVLATVF

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=227, Percent_Identity=28.6343612334802, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI94538354, Length=202, Percent_Identity=24.2574257425743, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71999683, Length=202, Percent_Identity=24.2574257425743, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17553678, Length=186, Percent_Identity=25.8064516129032, Blast_Score=72, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6323192, Length=415, Percent_Identity=20.9638554216867, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321813, Length=415, Percent_Identity=20.9638554216867, Blast_Score=63, Evalue=9e-11,
Organism=Drosophila melanogaster, GI21357875, Length=203, Percent_Identity=24.6305418719212, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24646943, Length=203, Percent_Identity=24.6305418719212, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 45119; Mature: 45119

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRTTLASGLRVLVLNNPAVDIVSARFFLRVDSRTDTPPGLAHLVSAVLTKGTEARDSMA
CCCCCHHCCCEEEEECCCCHHHEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHH
IAQIVESLGAMLGADSTPDYLQIALKSLGEDFPTLLALAAELLQRATFPAEQIEIERKAT
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LQAIRSQQERPFTVAYNQFRAALYGNSPYAYPELGTEESVLALRREDLLNFYRAHFRPDN
HHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
AVFVAVGPLEPEAVVRLLEEHLGGWSVPETPLLRTALLKPTDAFPTATLRTVQPTQQSTV
EEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCEEEEECCCCCCEE
LVGYPAAPIHSEDFAALKLIGTYLGSGLSSRLFTELREKRGLAYEVSAFYPTRASTSHFV
EEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEE
AYIGTAPENARTCEAGLRTEVERLASTPLGDSELRTAKNKLLGQYALGKQTNSQVAQLLG
EEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
WYEILGVGADFDREYTRTVEQLTSADLLAVAERTFKAPIVSLVGPEDVLATVF
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHCC
>Mature Secondary Structure
MFRTTLASGLRVLVLNNPAVDIVSARFFLRVDSRTDTPPGLAHLVSAVLTKGTEARDSMA
CCCCCHHCCCEEEEECCCCHHHEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHH
IAQIVESLGAMLGADSTPDYLQIALKSLGEDFPTLLALAAELLQRATFPAEQIEIERKAT
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LQAIRSQQERPFTVAYNQFRAALYGNSPYAYPELGTEESVLALRREDLLNFYRAHFRPDN
HHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
AVFVAVGPLEPEAVVRLLEEHLGGWSVPETPLLRTALLKPTDAFPTATLRTVQPTQQSTV
EEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCEEEEECCCCCCEE
LVGYPAAPIHSEDFAALKLIGTYLGSGLSSRLFTELREKRGLAYEVSAFYPTRASTSHFV
EEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEE
AYIGTAPENARTCEAGLRTEVERLASTPLGDSELRTAKNKLLGQYALGKQTNSQVAQLLG
EEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
WYEILGVGADFDREYTRTVEQLTSADLLAVAERTFKAPIVSLVGPEDVLATVF
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]