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The map label for this gene is sufS [C]

Identifier: 37520942

GI number: 37520942

Start: 1469228

End: 1470481

Strand: Direct

Name: sufS [C]

Synonym: glr1373

Alternate gene names: 37520942

Gene position: 1469228-1470481 (Clockwise)

Preceding gene: 37520941

Following gene: 37520943

Centisome position: 31.54

GC content: 63.32

Gene sequence:

>1254_bases
ATGACCTTCACCGCCCAAGCTCACCGGACCCTGACTCCCGCCGCCGTCGAACGCCTGCGCGCCGATTTTCCGATTTTGCG
CCAGACCGTCTACGGCAAGCCGCTGGTTTACCTGGACAACGCCGCCACCACCCAGAAGCCCCAGGCGGTGCTCGACGCCA
TCGCCGCACTCTACACCGGCTATTACTCGAACATCCACCGCGGCGTGCACCACCTCAGTCAGCTTTCTACCGAAGCCCAC
GAACAGGCCCGCATCAAGGTGCAGCAATTTATAAACGCCCAGAGCGATCGCGAGATCGTCTTCGTGCGCGGCTGCACCGA
GGGGATCAACCTGGTGGCCCAGACGTTTGGCCGCGAGCGCGTCGGTCCGGGCGACGAGATTGTCATTTCCGCCATGGAGC
ACCACTCCAACATCGTTCCCTGGCAGATGCTCTGCCAGGAAAAAGGAGCGATCCTCAAAGTGGCGCCCATCGACGATCGC
GGCGAAATCATCCTTGAAGCCTTCGAGCAACTCCTGGGCGAGCGCACGAAGCTGGTGGCGGTGGTGCACCTGTCGAACGC
TCTGGGTACGATTAACCCGGTGGCGCGCTTGATTGAACTGGCCCACACCCGCGGCATTCCGGTGCTGGTGGACGGCGCCC
AGGCGGTGTCCCATATTGCCGTGGACGTGCAGGCGCTCGACTGCGACTTTTACGTTTTCTCGGGCCACAAGCTCTACGCG
CCTACCGGCATCGGCGTGCTCTACGGCAAGGCGGAACTGCTGGAGGCGATGTCCCCCTGGCAGGGCGGCGGAGACATGAT
CCGCTCGGTCAGCTTCGAGAAGACGATCTACAGCGACTTGCCCTACAAATTCGAAGCGGGTACCCCGGACATCGCCGGGG
CCATCGCCCTGGGTGTTGCCGTCGACTATGTGCAGCACATCGGCCTGGAGGCGATTGCAGGCTACGAGCAGGAACTGCTC
GATTACGCCACCGAAGCGCTCAGCGCCATCGACGGCGTCAAGCTCATCGGTACCGCCCGCGATAAGGCGAGCGTGCTTTC
TTTTGTGCTGGCCGGGGTCCATCCCCACGACATCGGCACGATTCTCGACCGCAAAGGCATCGCCGTACGGGCGGGCCACC
ACTGCGCCCAGCCGGTGATGCAGCGCTTCAAGGTGCCGGCCACCGCCCGCGCCTCGTTCGCCTTTTACAACACCCGCGCC
GAGGTCGATGCGCTGGTGGCGGCAATCCAACAAGTGCAGGAGATGTTTAGCTGA

Upstream 100 bases:

>100_bases
ACCTGTTCGAAGATATCCGGCTTGCCGCCCTGCGCGACCGGCTGGAGACCCTTTTGTACACCTGGCTCTCCTTTGAGGCC
GGAATTGCCGGAACGCAACC

Downstream 100 bases:

>100_bases
TGTTCTCGGATCTGCGCGATCTCTATCAAGAAGTGATCCTCGACCACTACAAGCGTCCGCGCAATTTCGGATTGCTGGAG
GCGGCCAACCGCGAGGCGGA

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MTFTAQAHRTLTPAAVERLRADFPILRQTVYGKPLVYLDNAATTQKPQAVLDAIAALYTGYYSNIHRGVHHLSQLSTEAH
EQARIKVQQFINAQSDREIVFVRGCTEGINLVAQTFGRERVGPGDEIVISAMEHHSNIVPWQMLCQEKGAILKVAPIDDR
GEIILEAFEQLLGERTKLVAVVHLSNALGTINPVARLIELAHTRGIPVLVDGAQAVSHIAVDVQALDCDFYVFSGHKLYA
PTGIGVLYGKAELLEAMSPWQGGGDMIRSVSFEKTIYSDLPYKFEAGTPDIAGAIALGVAVDYVQHIGLEAIAGYEQELL
DYATEALSAIDGVKLIGTARDKASVLSFVLAGVHPHDIGTILDRKGIAVRAGHHCAQPVMQRFKVPATARASFAFYNTRA
EVDALVAAIQQVQEMFS

Sequences:

>Translated_417_residues
MTFTAQAHRTLTPAAVERLRADFPILRQTVYGKPLVYLDNAATTQKPQAVLDAIAALYTGYYSNIHRGVHHLSQLSTEAH
EQARIKVQQFINAQSDREIVFVRGCTEGINLVAQTFGRERVGPGDEIVISAMEHHSNIVPWQMLCQEKGAILKVAPIDDR
GEIILEAFEQLLGERTKLVAVVHLSNALGTINPVARLIELAHTRGIPVLVDGAQAVSHIAVDVQALDCDFYVFSGHKLYA
PTGIGVLYGKAELLEAMSPWQGGGDMIRSVSFEKTIYSDLPYKFEAGTPDIAGAIALGVAVDYVQHIGLEAIAGYEQELL
DYATEALSAIDGVKLIGTARDKASVLSFVLAGVHPHDIGTILDRKGIAVRAGHHCAQPVMQRFKVPATARASFAFYNTRA
EVDALVAAIQQVQEMFS
>Mature_416_residues
TFTAQAHRTLTPAAVERLRADFPILRQTVYGKPLVYLDNAATTQKPQAVLDAIAALYTGYYSNIHRGVHHLSQLSTEAHE
QARIKVQQFINAQSDREIVFVRGCTEGINLVAQTFGRERVGPGDEIVISAMEHHSNIVPWQMLCQEKGAILKVAPIDDRG
EIILEAFEQLLGERTKLVAVVHLSNALGTINPVARLIELAHTRGIPVLVDGAQAVSHIAVDVQALDCDFYVFSGHKLYAP
TGIGVLYGKAELLEAMSPWQGGGDMIRSVSFEKTIYSDLPYKFEAGTPDIAGAIALGVAVDYVQHIGLEAIAGYEQELLD
YATEALSAIDGVKLIGTARDKASVLSFVLAGVHPHDIGTILDRKGIAVRAGHHCAQPVMQRFKVPATARASFAFYNTRAE
VDALVAAIQQVQEMFS

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=247, Percent_Identity=30.7692307692308, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI156713448, Length=426, Percent_Identity=25.1173708920188, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1787970, Length=403, Percent_Identity=53.3498759305211, Blast_Score=444, Evalue=1e-126,
Organism=Escherichia coli, GI1789175, Length=399, Percent_Identity=44.6115288220551, Blast_Score=347, Evalue=9e-97,
Organism=Escherichia coli, GI48994898, Length=215, Percent_Identity=32.093023255814, Blast_Score=104, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI25143064, Length=213, Percent_Identity=29.1079812206573, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI193211090, Length=464, Percent_Identity=25, Blast_Score=95, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6319831, Length=243, Percent_Identity=31.2757201646091, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI20129463, Length=365, Percent_Identity=27.3972602739726, Blast_Score=121, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 45329; Mature: 45198

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFTAQAHRTLTPAAVERLRADFPILRQTVYGKPLVYLDNAATTQKPQAVLDAIAALYTG
CCCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHH
YYSNIHRGVHHLSQLSTEAHEQARIKVQQFINAQSDREIVFVRGCTEGINLVAQTFGRER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCC
VGPGDEIVISAMEHHSNIVPWQMLCQEKGAILKVAPIDDRGEIILEAFEQLLGERTKLVA
CCCCHHHHHEEHHHCCCCCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCHHEEEE
VVHLSNALGTINPVARLIELAHTRGIPVLVDGAQAVSHIAVDVQALDCDFYVFSGHKLYA
EEEECCCCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHEEEEEEEEEEEEEECCEEEC
PTGIGVLYGKAELLEAMSPWQGGGDMIRSVSFEKTIYSDLPYKFEAGTPDIAGAIALGVA
CCCCCCEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHH
VDYVQHIGLEAIAGYEQELLDYATEALSAIDGVKLIGTARDKASVLSFVLAGVHPHDIGT
HHHHHHCCHHHHHCHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCHHHHH
ILDRKGIAVRAGHHCAQPVMQRFKVPATARASFAFYNTRAEVDALVAAIQQVQEMFS
HHCCCCCEEECCCHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TFTAQAHRTLTPAAVERLRADFPILRQTVYGKPLVYLDNAATTQKPQAVLDAIAALYTG
CCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHH
YYSNIHRGVHHLSQLSTEAHEQARIKVQQFINAQSDREIVFVRGCTEGINLVAQTFGRER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCC
VGPGDEIVISAMEHHSNIVPWQMLCQEKGAILKVAPIDDRGEIILEAFEQLLGERTKLVA
CCCCHHHHHEEHHHCCCCCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCHHEEEE
VVHLSNALGTINPVARLIELAHTRGIPVLVDGAQAVSHIAVDVQALDCDFYVFSGHKLYA
EEEECCCCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHEEEEEEEEEEEEEECCEEEC
PTGIGVLYGKAELLEAMSPWQGGGDMIRSVSFEKTIYSDLPYKFEAGTPDIAGAIALGVA
CCCCCCEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHH
VDYVQHIGLEAIAGYEQELLDYATEALSAIDGVKLIGTARDKASVLSFVLAGVHPHDIGT
HHHHHHCCHHHHHCHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCHHHHH
ILDRKGIAVRAGHHCAQPVMQRFKVPATARASFAFYNTRAEVDALVAAIQQVQEMFS
HHCCCCCEEECCCHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA