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The map label for this gene is ilvE [H]

Identifier: 37520794

GI number: 37520794

Start: 1302381

End: 1303340

Strand: Reverse

Name: ilvE [H]

Synonym: gll1225

Alternate gene names: 37520794

Gene position: 1303340-1302381 (Counterclockwise)

Preceding gene: 37520795

Following gene: 37520786

Centisome position: 27.97

GC content: 62.81

Gene sequence:

>960_bases
ATGACCCAGCCATCTTCCGAACCCGTCATCTACCTGCGCGGTCGCTTCGTCCCGGACAGCGAGGCTTCTTTGAGCGTGCG
CACCCATGCTTTTTTGTACGGCACCGCCGTCTTCGAGGGCATCAAGGCGTACTGGGCGCCCGAGCGCGAGACGATGTTCA
TCTTTCGCGCCGAGGAGCATTTTCGCAGGCTGGTGCAAAGCTGCCGCATCCTTCGCCTCAAGGCACCCCTGGATATCCGG
CGGATGGTGGAGTTGAGTGCGGAGATTGTTGTGCGCAACGGCTGCCGCGAGGACACTTACTTGCGCCCGATTGTCTACAA
AGCCGACCGGCGCATCGGTCCAATCCTGGAGATTCCCGATACGGTCGACGACTTTTGTCTGTTTACCGCCCCGATGAGCG
CCTACCTGGATACGCACAAAGGTCTGCACGTCTGCGTCTCCTCCTGGCGCCGCATCGACGACAACATGATCCCGGCGCGC
GCCAAGTGCAACGGCGCCTACGTCAACACCGCGCTGATCAAGACCGACGCCGCTCTGGCCGGTTTCGACGACGCCATCGC
CCTATCGGATGACGGCCACGTCGCCGAAGGCAGTGCGATGAATTTGTTCCTGGTGCGCGACGGCCGACTGGTCACCCCAG
CGGTGAGCAACAACATCCTCGAAGGGATCACCCGCGCCACGGTCATCGAACTAGCCCGGAAAGAACTGGGGATCCCAGTC
GAATCGCGGCAGGTGGACCGTACTGAACTCTATGTTGCCGAGGAGATGTTCCTGTGCGGCACGGCCACCGAGGTGGCGGC
GGTCACCCGCATCGACCACCGCGCCATCGGCGACGGCACCGTGGGACCGATCACCCGGGCGATTCAAGATCTCTTCGACC
AGGCCATCCACGGCCGTCTGCCCGACTATATGCACTGGCTGACCCCCGCTGGCACCCCAGTGCTGAGCAGCCAGGACTGA

Upstream 100 bases:

>100_bases
CAAACGGTGTAACGAAATTGCGACACATCGTCCGGTCCGCCCTTGCAATTGGAGCACAATTGGAACGGCCAGGCTTCGTA
TCGATACCTCAAGGACCACC

Downstream 100 bases:

>100_bases
GGCTTATCTGGGCGGTTCCCGGGGTTTGTGCTTTAGCCTCGGGAGCAACTTTGGAGACTCCCGCTCGGCGACCCGGATAT
TGGCGGTCGGCTCGCCGGGC

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MTQPSSEPVIYLRGRFVPDSEASLSVRTHAFLYGTAVFEGIKAYWAPERETMFIFRAEEHFRRLVQSCRILRLKAPLDIR
RMVELSAEIVVRNGCREDTYLRPIVYKADRRIGPILEIPDTVDDFCLFTAPMSAYLDTHKGLHVCVSSWRRIDDNMIPAR
AKCNGAYVNTALIKTDAALAGFDDAIALSDDGHVAEGSAMNLFLVRDGRLVTPAVSNNILEGITRATVIELARKELGIPV
ESRQVDRTELYVAEEMFLCGTATEVAAVTRIDHRAIGDGTVGPITRAIQDLFDQAIHGRLPDYMHWLTPAGTPVLSSQD

Sequences:

>Translated_319_residues
MTQPSSEPVIYLRGRFVPDSEASLSVRTHAFLYGTAVFEGIKAYWAPERETMFIFRAEEHFRRLVQSCRILRLKAPLDIR
RMVELSAEIVVRNGCREDTYLRPIVYKADRRIGPILEIPDTVDDFCLFTAPMSAYLDTHKGLHVCVSSWRRIDDNMIPAR
AKCNGAYVNTALIKTDAALAGFDDAIALSDDGHVAEGSAMNLFLVRDGRLVTPAVSNNILEGITRATVIELARKELGIPV
ESRQVDRTELYVAEEMFLCGTATEVAAVTRIDHRAIGDGTVGPITRAIQDLFDQAIHGRLPDYMHWLTPAGTPVLSSQD
>Mature_318_residues
TQPSSEPVIYLRGRFVPDSEASLSVRTHAFLYGTAVFEGIKAYWAPERETMFIFRAEEHFRRLVQSCRILRLKAPLDIRR
MVELSAEIVVRNGCREDTYLRPIVYKADRRIGPILEIPDTVDDFCLFTAPMSAYLDTHKGLHVCVSSWRRIDDNMIPARA
KCNGAYVNTALIKTDAALAGFDDAIALSDDGHVAEGSAMNLFLVRDGRLVTPAVSNNILEGITRATVIELARKELGIPVE
SRQVDRTELYVAEEMFLCGTATEVAAVTRIDHRAIGDGTVGPITRAIQDLFDQAIHGRLPDYMHWLTPAGTPVLSSQD

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=301, Percent_Identity=35.5481727574751, Blast_Score=189, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17565728, Length=285, Percent_Identity=27.3684210526316, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 35550; Mature: 35419

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPSSEPVIYLRGRFVPDSEASLSVRTHAFLYGTAVFEGIKAYWAPERETMFIFRAEEH
CCCCCCCCEEEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHH
FRRLVQSCRILRLKAPLDIRRMVELSAEIVVRNGCREDTYLRPIVYKADRRIGPILEIPD
HHHHHHHHHEEEECCCHHHHHHHHHHHHHEEECCCCCCCCCCCEEEECCCCCCCEEECCC
TVDDFCLFTAPMSAYLDTHKGLHVCVSSWRRIDDNMIPARAKCNGAYVNTALIKTDAALA
CHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCHHC
GFDDAIALSDDGHVAEGSAMNLFLVRDGRLVTPAVSNNILEGITRATVIELARKELGIPV
CCCCEEEECCCCCCCCCCCEEEEEEECCEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ESRQVDRTELYVAEEMFLCGTATEVAAVTRIDHRAIGDGTVGPITRAIQDLFDQAIHGRL
CCCCCCHHHHEEEHHHHEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
PDYMHWLTPAGTPVLSSQD
CHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TQPSSEPVIYLRGRFVPDSEASLSVRTHAFLYGTAVFEGIKAYWAPERETMFIFRAEEH
CCCCCCCEEEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHH
FRRLVQSCRILRLKAPLDIRRMVELSAEIVVRNGCREDTYLRPIVYKADRRIGPILEIPD
HHHHHHHHHEEEECCCHHHHHHHHHHHHHEEECCCCCCCCCCCEEEECCCCCCCEEECCC
TVDDFCLFTAPMSAYLDTHKGLHVCVSSWRRIDDNMIPARAKCNGAYVNTALIKTDAALA
CHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCHHC
GFDDAIALSDDGHVAEGSAMNLFLVRDGRLVTPAVSNNILEGITRATVIELARKELGIPV
CCCCEEEECCCCCCCCCCCEEEEEEECCEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ESRQVDRTELYVAEEMFLCGTATEVAAVTRIDHRAIGDGTVGPITRAIQDLFDQAIHGRL
CCCCCCHHHHEEEHHHHEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
PDYMHWLTPAGTPVLSSQD
CHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]