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The map label for this gene is 37520795

Identifier: 37520795

GI number: 37520795

Start: 1303476

End: 1304993

Strand: Reverse

Name: 37520795

Synonym: gll1226

Alternate gene names: NA

Gene position: 1304993-1303476 (Counterclockwise)

Preceding gene: 37520797

Following gene: 37520794

Centisome position: 28.01

GC content: 68.91

Gene sequence:

>1518_bases
ATGGATGCGATCGAACTGGAAGTGATGGTCCATGCCCTTGCCGGCATTGCTGAGGAGATGATGGCGCGGCTGGTGCGCGC
CGCTTACTCTTCGAATATCAAGGAGCGCCGCGACTGCTCGACGGCCCTTTTCGACGGGCGGGGCCGCCTGGTGGCGCAGG
CGGCGGCGATCCCGGTGCACCTGGGGGCGCTCGGGGACGCAGTGGCGGCGGTGCGGGCGATGGACCCAAAGCCGGGGGAA
ATCTGGCTGTTGAACGACCCGTTCGCGGGCGGCTCGCACCTGCCGGATCTGACCCTGGTGACGGCGATTGCCTGGCTGGA
TCGGCCGCAGGAGCGATTGGGCTACGCCGTCTCCCGCGCTCACCACAGCGATGTGGGCGGCATGCGGCCGGGTTCGATGC
CCGCCGACTCCACCGAGATTTTTCAAGAAGGACTGGTGATCCCGCCTACGCGCGTCGGTGCGGCGGGGGCGCTCGACGAA
AATGTGCTCGGTTTGATTCTGGCCAACGTCCGCCAGCCTGCCCAGCGCCGGGGGGATCTGCGCGCCCAGATGGCGGCGGG
TCAATTGGGGGCGGAGCGCTTCGCCCGGATGGGGAGCGATCTGGGAGCGGACAGGCTCGCGGGCGCCTTGGACGCGGTCA
TTGTCTACACCGAGCGGCGGGTGCGCGAGCGCATCGCTGCCCTTCCCGACGGCACCTATCGGGCCGTCGACTACCTCGAA
GGCCCCGAGGGCGAGGAGATTGCGATCCAGGTGGCGGTGGAAATAGCCGGCGATGGGGTGCGCATCGATTTTGCGGGCAC
CGCGTCCCAGGTACTTTCCAACCTCAACGCGCCTGTCGCGGTCACCCGCTCGGCGGTGGCGTTTGCCTTGCGCGCCCTGC
TCGATCCGCACCTGCCCGCCAACGACGGGGCGATGGCGCCGGTAGAACTGGTGCTGCCGGAGGGTTCTCTGGTGGCGGCG
CGCTGGCCGGCGGCGGTGGTGGCGGGCAACGTCGAGACTTCCCAGCGCATCGCCGATGCGATCATCCTCGCCCTGGGCAG
TGTCGCGGGCGGCCTTGCCCAGGGGCAGGGCACGATGAACAATCTGATCCTGGGCAACCGCCGCTTCAGCTACTACGAGA
CGATCGGGGGCGGCCAGGGGGCGAGTGCCTGCGGCGACGGCCTCGACGGGGTGCACGTCGGTATGAGCAACACCCTTAAT
ACCCCCATCGAGGCGCTCGAACTGGAATTTCCGCTCACCGTCCGGCGCTACGAACTGCGCGAAGATTCGGGCGGGGCGGG
CTTCTACCGCGGCGGCTGGGGGATCGTCCGCGAGGTGCAGGTGCACGAAGATTGCTCCCTTTCGCTATTGAGCGATCGCC
GCACTCACGCTCCCCAGGGGGCGGCGGGCGGCGCGGCGGGCCGACCGGGCCGCAACCGGCTTAACGGTGAACCGCTTCCA
GGCAAGACTTCGCGCGCGCTCAAGGCGGGGGATGTGATCACCGTCGAGACACCGGGGGGTGGCGGTTGGGGAGCATAG

Upstream 100 bases:

>100_bases
CCCGCCTTTGCCCAACAGAGAAATCACGCGCGCCATAGCCTACCCCCGAAGTCCTGACCTATCGTATAGTTCATAGCCCG
GCAACCGAAAGAGCGGCCCG

Downstream 100 bases:

>100_bases
GGCTCTGTCCCCCCTCATGGCTGTGGTAAATTCTGCAAACGGTGTAACGAAATTGCGACACATCGTCCGGTCCGCCCTTG
CAATTGGAGCACAATTGGAA

Product: hypothetical protein

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MDAIELEVMVHALAGIAEEMMARLVRAAYSSNIKERRDCSTALFDGRGRLVAQAAAIPVHLGALGDAVAAVRAMDPKPGE
IWLLNDPFAGGSHLPDLTLVTAIAWLDRPQERLGYAVSRAHHSDVGGMRPGSMPADSTEIFQEGLVIPPTRVGAAGALDE
NVLGLILANVRQPAQRRGDLRAQMAAGQLGAERFARMGSDLGADRLAGALDAVIVYTERRVRERIAALPDGTYRAVDYLE
GPEGEEIAIQVAVEIAGDGVRIDFAGTASQVLSNLNAPVAVTRSAVAFALRALLDPHLPANDGAMAPVELVLPEGSLVAA
RWPAAVVAGNVETSQRIADAIILALGSVAGGLAQGQGTMNNLILGNRRFSYYETIGGGQGASACGDGLDGVHVGMSNTLN
TPIEALELEFPLTVRRYELREDSGGAGFYRGGWGIVREVQVHEDCSLSLLSDRRTHAPQGAAGGAAGRPGRNRLNGEPLP
GKTSRALKAGDVITVETPGGGGWGA

Sequences:

>Translated_505_residues
MDAIELEVMVHALAGIAEEMMARLVRAAYSSNIKERRDCSTALFDGRGRLVAQAAAIPVHLGALGDAVAAVRAMDPKPGE
IWLLNDPFAGGSHLPDLTLVTAIAWLDRPQERLGYAVSRAHHSDVGGMRPGSMPADSTEIFQEGLVIPPTRVGAAGALDE
NVLGLILANVRQPAQRRGDLRAQMAAGQLGAERFARMGSDLGADRLAGALDAVIVYTERRVRERIAALPDGTYRAVDYLE
GPEGEEIAIQVAVEIAGDGVRIDFAGTASQVLSNLNAPVAVTRSAVAFALRALLDPHLPANDGAMAPVELVLPEGSLVAA
RWPAAVVAGNVETSQRIADAIILALGSVAGGLAQGQGTMNNLILGNRRFSYYETIGGGQGASACGDGLDGVHVGMSNTLN
TPIEALELEFPLTVRRYELREDSGGAGFYRGGWGIVREVQVHEDCSLSLLSDRRTHAPQGAAGGAAGRPGRNRLNGEPLP
GKTSRALKAGDVITVETPGGGGWGA
>Mature_505_residues
MDAIELEVMVHALAGIAEEMMARLVRAAYSSNIKERRDCSTALFDGRGRLVAQAAAIPVHLGALGDAVAAVRAMDPKPGE
IWLLNDPFAGGSHLPDLTLVTAIAWLDRPQERLGYAVSRAHHSDVGGMRPGSMPADSTEIFQEGLVIPPTRVGAAGALDE
NVLGLILANVRQPAQRRGDLRAQMAAGQLGAERFARMGSDLGADRLAGALDAVIVYTERRVRERIAALPDGTYRAVDYLE
GPEGEEIAIQVAVEIAGDGVRIDFAGTASQVLSNLNAPVAVTRSAVAFALRALLDPHLPANDGAMAPVELVLPEGSLVAA
RWPAAVVAGNVETSQRIADAIILALGSVAGGLAQGQGTMNNLILGNRRFSYYETIGGGQGASACGDGLDGVHVGMSNTLN
TPIEALELEFPLTVRRYELREDSGGAGFYRGGWGIVREVQVHEDCSLSLLSDRRTHAPQGAAGGAAGRPGRNRLNGEPLP
GKTSRALKAGDVITVETPGGGGWGA

Specific function: Unknown

COG id: COG0146

COG function: function code EQ; N-methylhydantoinase B/acetone carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=533, Percent_Identity=40.7129455909944, Blast_Score=318, Evalue=9e-87,
Organism=Caenorhabditis elegans, GI133901900, Length=530, Percent_Identity=36.2264150943396, Blast_Score=301, Evalue=5e-82,
Organism=Caenorhabditis elegans, GI133901902, Length=499, Percent_Identity=35.6713426853707, Blast_Score=278, Evalue=4e-75,
Organism=Saccharomyces cerevisiae, GI6322634, Length=545, Percent_Identity=34.4954128440367, Blast_Score=303, Evalue=6e-83,
Organism=Drosophila melanogaster, GI45550492, Length=531, Percent_Identity=37.6647834274953, Blast_Score=313, Evalue=2e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003692 [H]

Pfam domain/function: PF02538 Hydantoinase_B [H]

EC number: 3.5.2.14

Molecular weight: Translated: 52746; Mature: 52746

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAIELEVMVHALAGIAEEMMARLVRAAYSSNIKERRDCSTALFDGRGRLVAQAAAIPVH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEHHHCEEE
LGALGDAVAAVRAMDPKPGEIWLLNDPFAGGSHLPDLTLVTAIAWLDRPQERLGYAVSRA
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
HHSDVGGMRPGSMPADSTEIFQEGLVIPPTRVGAAGALDENVLGLILANVRQPAQRRGDL
HHCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCH
RAQMAAGQLGAERFARMGSDLGADRLAGALDAVIVYTERRVRERIAALPDGTYRAVDYLE
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEHHHHHHHHHHHHCCCCCCHHHHHCC
GPEGEEIAIQVAVEIAGDGVRIDFAGTASQVLSNLNAPVAVTRSAVAFALRALLDPHLPA
CCCCCEEEEEEEEEECCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCC
NDGAMAPVELVLPEGSLVAARWPAAVVAGNVETSQRIADAIILALGSVAGGLAQGQGTMN
CCCCCCCEEEEECCCCEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHCCHHCCCCCHH
NLILGNRRFSYYETIGGGQGASACGDGLDGVHVGMSNTLNTPIEALELEFPLTVRRYELR
HEEECCCCCCHHHHCCCCCCCCHHCCCCCCEEECCCCCCCCCHHHEEEECCCEEEEEEEC
EDSGGAGFYRGGWGIVREVQVHEDCSLSLLSDRRTHAPQGAAGGAAGRPGRNRLNGEPLP
CCCCCCCEEECCCCEEEEEEECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GKTSRALKAGDVITVETPGGGGWGA
CCCCCCEECCCEEEEECCCCCCCCC
>Mature Secondary Structure
MDAIELEVMVHALAGIAEEMMARLVRAAYSSNIKERRDCSTALFDGRGRLVAQAAAIPVH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEHHHCEEE
LGALGDAVAAVRAMDPKPGEIWLLNDPFAGGSHLPDLTLVTAIAWLDRPQERLGYAVSRA
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
HHSDVGGMRPGSMPADSTEIFQEGLVIPPTRVGAAGALDENVLGLILANVRQPAQRRGDL
HHCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCH
RAQMAAGQLGAERFARMGSDLGADRLAGALDAVIVYTERRVRERIAALPDGTYRAVDYLE
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEHHHHHHHHHHHHCCCCCCHHHHHCC
GPEGEEIAIQVAVEIAGDGVRIDFAGTASQVLSNLNAPVAVTRSAVAFALRALLDPHLPA
CCCCCEEEEEEEEEECCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCC
NDGAMAPVELVLPEGSLVAARWPAAVVAGNVETSQRIADAIILALGSVAGGLAQGQGTMN
CCCCCCCEEEEECCCCEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHCCHHCCCCCHH
NLILGNRRFSYYETIGGGQGASACGDGLDGVHVGMSNTLNTPIEALELEFPLTVRRYELR
HEEECCCCCCHHHHCCCCCCCCHHCCCCCCEEECCCCCCCCCHHHEEEECCCEEEEEEEC
EDSGGAGFYRGGWGIVREVQVHEDCSLSLLSDRRTHAPQGAAGGAAGRPGRNRLNGEPLP
CCCCCCCEEECCCCEEEEEEECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GKTSRALKAGDVITVETPGGGGWGA
CCCCCCEECCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]