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The map label for this gene is resE [H]

Identifier: 37520383

GI number: 37520383

Start: 868822

End: 870978

Strand: Reverse

Name: resE [H]

Synonym: gll0814

Alternate gene names: 37520383

Gene position: 870978-868822 (Counterclockwise)

Preceding gene: 37520384

Following gene: 37520382

Centisome position: 18.69

GC content: 67.27

Gene sequence:

>2157_bases
ATGGCTACCCGGTTGCGCACCCAGTATCAGCTTGCCTTTGCGCTGGCGGCCCTCGTGCCGGTGGCGGTCTTGGGGCTGGT
CGAGTTTGCTCTGTTTCGACGCGCCCTGCCGGAGCGCGAACAGGCGGTGCTCGACGATCACCTGCGCCTGGCGGATCTGC
TGGCGAGCAACCTGCGCTACGAGTTGAACCTGGTGCTCGAGCCGGTGCAAAAAGCCGCCGACCCACGCTCAGCCCTTACC
CGCCTCAGATCTGCCGAGCAAGATGGGGCTCTGGCGCGCTTAATGAGCACCACGCCGCTGTTTCGCCATCTGCTGCTGGT
GGATGGTCGCCGCCGGGTGACGGCGAGTGCCAAGCCGACGCTCTGGCGGGGTCGGGTGCTGCCGGCTTCGGTCTTCCCGA
CTACCGGGGCGGCAGGACCCGTGTACTACTCCTCCGTCTTCGCTTCGATCTACGACGGCGCGCCGCTGGCCGCCATCGCC
GTCGCCTATCCGACCTTTGAACGGGGGGCACTCGTCAGCCTGCTCGATCTGGGCGCCATCGAGAGTCAGGTGCGCTCGCA
GTCCACCGCCGACCGCCAGATCTGGGTGGTCGACAGGACCGGTCATACCCTGGCCCACTCCCAGGGACAGCTGGCCCTCA
GCGGCGCGGTGCCGACGGAACTGCCTCCGGTCCGCCAGGTACTCAAAAATCGGCGCGGCACTGCGCGCTACGAGCAGCCG
GTGGACAGCGACCGGGTGGAGCAACTGGCGGCGTTTGCACCGATCGCCGGTACCGATTGGGGTGTCGTGGTGACGAGCCC
CGCCCGCGCGGCCCTCGCCGATCCGTTGGTGGGCCTGCAGCGGTTCGCCGCGGGGCTGCTTTTCGTCGCCGCCGCCGCCG
TTGGATTCGCCTACTGGTTGAGCGAACGCATCAGCCGGCCGCTGCAGCAACTGAGCGAGCAGATGCAAAACCAGGCGCTC
GCAGCACCGACTGCCCAGGTGGGACCACCGATGCCGACGGCGCCGGCCCTGGAGTTACAGGTGCTCATCGACTCGTTCGG
GGCGATGCGCGAGCGCATCGGCGCGGAGGCGGAGGCCAACCGCCGCTTGCTTGCCAACCTCACCGCCGAAAAAGACAAGC
TCGAACTGGTGATCGAAGCGATCGCCGAAGGGGTACTGGTCTACGATTCGTCCGGGCGGCTGCGCACTGCCAACCGGGCG
CTCTGGTCGCTATTGGACAGTCCGCCGGGGGAGCTCGCGCACTGGCGGACGCTGCGGCTGCGCGACGCCCTCGGCGAACC
GGTCGCACCGGAGCGGACAGTCTTTGAGCGCGCCGTACGCGAAGGCAATCTTGCCAGCGATCTGTACCGCCTGGAGGGTT
CCGGCGCCCAACCGCGGGTGTTGCAGATTACTGCCGCCCCCCTGCGTACCGGGGAGGGCGAACTGTTGGGTGGTGTCGCC
GTTCTGCGCGACATCACTGCCCAAAAAGAAAGCGAGCGGCTGCGCGAAGATTTTGTCGCCACCCTCACCCACGATCTGCG
CACGCCGCTACTCGCGGCAGTCCAGACCCTGGGATTCACCCTCGATGGCCAGTACGGTCCTCTGAGCGACGGCCAGCAGC
AAATTCTCCTGGCGGTCATCGAGAGTCACCGCGAACTGTTGGGTCTGGTCGAAAGCCTGCTCACCATCTACCGCTACGAA
GCCGGGCGCATGCGGCTGCGCAAAGAACCGACGGATCTGGCCGCCTTTGTCGCTCAGGGCATCGAGGAGTTGCGCCCCCT
GGCTCAAAGCCGCAATCAGACATTGCTGGTGGAAGTGAGCGGACCGTTGCCGCCGGTGCCCTGCGACCGCCAGCAGCTGC
GGCGGGTGCTCGTCAATCTGGTGGACAACGCCCTCAAGTTCACCCCCGCCGGCGGCCGGGTGCACCTGCGCCTGGAGCCT
TTCGAGGGTGCTGTGCGCGTGGCGGTGCGCGACACCGGCCGGGGCATCCCGCCCGAAAAGAGTGTTCTGTTGTTCGTGCG
CTTTGCCCAGGCGGAAAGCTACGCCACCGGCACGGGGCTGGGGCTGTATCTGTGCCGACAGGTGGTCGAAGCGCACGGCG
GGCGGATCTGGGCTGAGAGCGAGCCGGGCCTCGGAAGCACGTTTTATTTCACACTGCCGCTTGCGGAGGGGCCATGA

Upstream 100 bases:

>100_bases
CCATTTGCTGATGACCGGTCCGGCCCGCAAGGTCTTCAGCGGCCTGCTGTAAGGGCTTCTTGAGCGGTTAACCTGAAAGC
CGGAGTCGACTGAACCATGC

Downstream 100 bases:

>100_bases
CCCGGATCTTGATCGTCGAAGACCACGCCCTGATGCGCATCGGATTGCGCCAGGTGCTCTCGCAGACTCCCGAGTACGAA
GTGGCGGGCGAAGCGGCGGA

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 718; Mature: 717

Protein sequence:

>718_residues
MATRLRTQYQLAFALAALVPVAVLGLVEFALFRRALPEREQAVLDDHLRLADLLASNLRYELNLVLEPVQKAADPRSALT
RLRSAEQDGALARLMSTTPLFRHLLLVDGRRRVTASAKPTLWRGRVLPASVFPTTGAAGPVYYSSVFASIYDGAPLAAIA
VAYPTFERGALVSLLDLGAIESQVRSQSTADRQIWVVDRTGHTLAHSQGQLALSGAVPTELPPVRQVLKNRRGTARYEQP
VDSDRVEQLAAFAPIAGTDWGVVVTSPARAALADPLVGLQRFAAGLLFVAAAAVGFAYWLSERISRPLQQLSEQMQNQAL
AAPTAQVGPPMPTAPALELQVLIDSFGAMRERIGAEAEANRRLLANLTAEKDKLELVIEAIAEGVLVYDSSGRLRTANRA
LWSLLDSPPGELAHWRTLRLRDALGEPVAPERTVFERAVREGNLASDLYRLEGSGAQPRVLQITAAPLRTGEGELLGGVA
VLRDITAQKESERLREDFVATLTHDLRTPLLAAVQTLGFTLDGQYGPLSDGQQQILLAVIESHRELLGLVESLLTIYRYE
AGRMRLRKEPTDLAAFVAQGIEELRPLAQSRNQTLLVEVSGPLPPVPCDRQQLRRVLVNLVDNALKFTPAGGRVHLRLEP
FEGAVRVAVRDTGRGIPPEKSVLLFVRFAQAESYATGTGLGLYLCRQVVEAHGGRIWAESEPGLGSTFYFTLPLAEGP

Sequences:

>Translated_718_residues
MATRLRTQYQLAFALAALVPVAVLGLVEFALFRRALPEREQAVLDDHLRLADLLASNLRYELNLVLEPVQKAADPRSALT
RLRSAEQDGALARLMSTTPLFRHLLLVDGRRRVTASAKPTLWRGRVLPASVFPTTGAAGPVYYSSVFASIYDGAPLAAIA
VAYPTFERGALVSLLDLGAIESQVRSQSTADRQIWVVDRTGHTLAHSQGQLALSGAVPTELPPVRQVLKNRRGTARYEQP
VDSDRVEQLAAFAPIAGTDWGVVVTSPARAALADPLVGLQRFAAGLLFVAAAAVGFAYWLSERISRPLQQLSEQMQNQAL
AAPTAQVGPPMPTAPALELQVLIDSFGAMRERIGAEAEANRRLLANLTAEKDKLELVIEAIAEGVLVYDSSGRLRTANRA
LWSLLDSPPGELAHWRTLRLRDALGEPVAPERTVFERAVREGNLASDLYRLEGSGAQPRVLQITAAPLRTGEGELLGGVA
VLRDITAQKESERLREDFVATLTHDLRTPLLAAVQTLGFTLDGQYGPLSDGQQQILLAVIESHRELLGLVESLLTIYRYE
AGRMRLRKEPTDLAAFVAQGIEELRPLAQSRNQTLLVEVSGPLPPVPCDRQQLRRVLVNLVDNALKFTPAGGRVHLRLEP
FEGAVRVAVRDTGRGIPPEKSVLLFVRFAQAESYATGTGLGLYLCRQVVEAHGGRIWAESEPGLGSTFYFTLPLAEGP
>Mature_717_residues
ATRLRTQYQLAFALAALVPVAVLGLVEFALFRRALPEREQAVLDDHLRLADLLASNLRYELNLVLEPVQKAADPRSALTR
LRSAEQDGALARLMSTTPLFRHLLLVDGRRRVTASAKPTLWRGRVLPASVFPTTGAAGPVYYSSVFASIYDGAPLAAIAV
AYPTFERGALVSLLDLGAIESQVRSQSTADRQIWVVDRTGHTLAHSQGQLALSGAVPTELPPVRQVLKNRRGTARYEQPV
DSDRVEQLAAFAPIAGTDWGVVVTSPARAALADPLVGLQRFAAGLLFVAAAAVGFAYWLSERISRPLQQLSEQMQNQALA
APTAQVGPPMPTAPALELQVLIDSFGAMRERIGAEAEANRRLLANLTAEKDKLELVIEAIAEGVLVYDSSGRLRTANRAL
WSLLDSPPGELAHWRTLRLRDALGEPVAPERTVFERAVREGNLASDLYRLEGSGAQPRVLQITAAPLRTGEGELLGGVAV
LRDITAQKESERLREDFVATLTHDLRTPLLAAVQTLGFTLDGQYGPLSDGQQQILLAVIESHRELLGLVESLLTIYRYEA
GRMRLRKEPTDLAAFVAQGIEELRPLAQSRNQTLLVEVSGPLPPVPCDRQQLRRVLVNLVDNALKFTPAGGRVHLRLEPF
EGAVRVAVRDTGRGIPPEKSVLLFVRFAQAESYATGTGLGLYLCRQVVEAHGGRIWAESEPGLGSTFYFTLPLAEGP

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=433, Percent_Identity=27.0207852193995, Blast_Score=113, Evalue=5e-26,
Organism=Escherichia coli, GI1786912, Length=240, Percent_Identity=32.9166666666667, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1789149, Length=239, Percent_Identity=31.7991631799163, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1788713, Length=232, Percent_Identity=28.448275862069, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1786600, Length=240, Percent_Identity=32.9166666666667, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI145693157, Length=239, Percent_Identity=30.9623430962343, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788549, Length=356, Percent_Identity=24.7191011235955, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788393, Length=234, Percent_Identity=28.6324786324786, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87081816, Length=231, Percent_Identity=32.4675324675325, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=26.4957264957265, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786783, Length=223, Percent_Identity=26.9058295964126, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1790551, Length=246, Percent_Identity=28.8617886178862, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI87082128, Length=269, Percent_Identity=27.5092936802974, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1790567, Length=344, Percent_Identity=25, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1788279, Length=210, Percent_Identity=28.0952380952381, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790300, Length=149, Percent_Identity=32.8859060402685, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78096; Mature: 77964

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRLRTQYQLAFALAALVPVAVLGLVEFALFRRALPEREQAVLDDHLRLADLLASNLRY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCE
ELNLVLEPVQKAADPRSALTRLRSAEQDGALARLMSTTPLFRHLLLVDGRRRVTASAKPT
EHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCC
LWRGRVLPASVFPTTGAAGPVYYSSVFASIYDGAPLAAIAVAYPTFERGALVSLLDLGAI
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHEECCCCCCCHHHHHHHHHHH
ESQVRSQSTADRQIWVVDRTGHTLAHSQGQLALSGAVPTELPPVRQVLKNRRGTARYEQP
HHHHHHCCCCCCEEEEEECCCCEECCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCCC
VDSDRVEQLAAFAPIAGTDWGVVVTSPARAALADPLVGLQRFAAGLLFVAAAAVGFAYWL
CCHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SERISRPLQQLSEQMQNQALAAPTAQVGPPMPTAPALELQVLIDSFGAMRERIGAEAEAN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
RRLLANLTAEKDKLELVIEAIAEGVLVYDSSGRLRTANRALWSLLDSPPGELAHWRTLRL
CHHHHHHHCCHHHHHHHHHHHHCCEEEECCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHH
RDALGEPVAPERTVFERAVREGNLASDLYRLEGSGAQPRVLQITAAPLRTGEGELLGGVA
HHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHH
VLRDITAQKESERLREDFVATLTHDLRTPLLAAVQTLGFTLDGQYGPLSDGQQQILLAVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHH
ESHRELLGLVESLLTIYRYEAGRMRLRKEPTDLAAFVAQGIEELRPLAQSRNQTLLVEVS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
GPLPPVPCDRQQLRRVLVNLVDNALKFTPAGGRVHLRLEPFEGAVRVAVRDTGRGIPPEK
CCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCEEEEEEEECCCCCCCCC
SVLLFVRFAQAESYATGTGLGLYLCRQVVEAHGGRIWAESEPGLGSTFYFTLPLAEGP
CEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEECCCCC
>Mature Secondary Structure 
ATRLRTQYQLAFALAALVPVAVLGLVEFALFRRALPEREQAVLDDHLRLADLLASNLRY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCE
ELNLVLEPVQKAADPRSALTRLRSAEQDGALARLMSTTPLFRHLLLVDGRRRVTASAKPT
EHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCC
LWRGRVLPASVFPTTGAAGPVYYSSVFASIYDGAPLAAIAVAYPTFERGALVSLLDLGAI
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHEECCCCCCCHHHHHHHHHHH
ESQVRSQSTADRQIWVVDRTGHTLAHSQGQLALSGAVPTELPPVRQVLKNRRGTARYEQP
HHHHHHCCCCCCEEEEEECCCCEECCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCCC
VDSDRVEQLAAFAPIAGTDWGVVVTSPARAALADPLVGLQRFAAGLLFVAAAAVGFAYWL
CCHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SERISRPLQQLSEQMQNQALAAPTAQVGPPMPTAPALELQVLIDSFGAMRERIGAEAEAN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
RRLLANLTAEKDKLELVIEAIAEGVLVYDSSGRLRTANRALWSLLDSPPGELAHWRTLRL
CHHHHHHHCCHHHHHHHHHHHHCCEEEECCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHH
RDALGEPVAPERTVFERAVREGNLASDLYRLEGSGAQPRVLQITAAPLRTGEGELLGGVA
HHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHH
VLRDITAQKESERLREDFVATLTHDLRTPLLAAVQTLGFTLDGQYGPLSDGQQQILLAVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHH
ESHRELLGLVESLLTIYRYEAGRMRLRKEPTDLAAFVAQGIEELRPLAQSRNQTLLVEVS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
GPLPPVPCDRQQLRRVLVNLVDNALKFTPAGGRVHLRLEPFEGAVRVAVRDTGRGIPPEK
CCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCEEEEEEEECCCCCCCCC
SVLLFVRFAQAESYATGTGLGLYLCRQVVEAHGGRIWAESEPGLGSTFYFTLPLAEGP
CEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]