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The map label for this gene is degU [H]

Identifier: 37520382

GI number: 37520382

Start: 868187

End: 868825

Strand: Reverse

Name: degU [H]

Synonym: gll0813

Alternate gene names: 37520382

Gene position: 868825-868187 (Counterclockwise)

Preceding gene: 37520383

Following gene: 37520381

Centisome position: 18.65

GC content: 68.86

Gene sequence:

>639_bases
ATGACCCGGATCTTGATCGTCGAAGACCACGCCCTGATGCGCATCGGATTGCGCCAGGTGCTCTCGCAGACTCCCGAGTA
CGAAGTGGCGGGCGAAGCGGCGGATGGCGAGCAGGCCCTCGCCCTCGCCCGCTCGTTGCAGCCCGATTTGGTGCTGATGG
ATCTGGGGCTGCCGGTGATGAGCGGCACCGAGGTGACGCGCATCCTCAAGCGCGAATACCCGGCGATGCGTGTCCTCGCA
CTCACCTCCCACGACGAGGACGAGAGCGTCTTCGGCGCCCTGGCCGCCGGAGCGGACGGCTACTGCCTCAAGGCGACCGC
CGGGATCGCCAGCCGCCTGCTGGCGGCCGTCGCTTCGGTGCGCGACGGGGCGGCCTGGCTCGACCCGGACATTGCCGATC
GGGTGCTTCGGGACCTGGGGCGCATTCCCCAGGCCGGGGCGGACAATCCGCTCTCGGAGCGCGAGATGGAAGTGCTCAAG
CTGATCGCCGACGGCCTCACCAACGCCGAAATCGGCCGGCGGCTCTACATCGCCTCCGGCACCGTGCGCGTGCACGTCAG
CAATATCATCGCCAAACTCGGCGTCAACGACCGGGTGCAGGCCGCCGTGCGCGCCCTGCGCGAAGGTTGGATCCGCTAG

Upstream 100 bases:

>100_bases
GCCGACAGGTGGTCGAAGCGCACGGCGGGCGGATCTGGGCTGAGAGCGAGCCGGGCCTCGGAAGCACGTTTTATTTCACA
CTGCCGCTTGCGGAGGGGCC

Downstream 100 bases:

>100_bases
TCGCAATCCCACTGAGCGGCAAATACGATCATCGGCCTATCTCCTGGGACACATAGTCGCCCGCACAATACGACACCCGG
CCTATGGGTGAATTGAAGGC

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MTRILIVEDHALMRIGLRQVLSQTPEYEVAGEAADGEQALALARSLQPDLVLMDLGLPVMSGTEVTRILKREYPAMRVLA
LTSHDEDESVFGALAAGADGYCLKATAGIASRLLAAVASVRDGAAWLDPDIADRVLRDLGRIPQAGADNPLSEREMEVLK
LIADGLTNAEIGRRLYIASGTVRVHVSNIIAKLGVNDRVQAAVRALREGWIR

Sequences:

>Translated_212_residues
MTRILIVEDHALMRIGLRQVLSQTPEYEVAGEAADGEQALALARSLQPDLVLMDLGLPVMSGTEVTRILKREYPAMRVLA
LTSHDEDESVFGALAAGADGYCLKATAGIASRLLAAVASVRDGAAWLDPDIADRVLRDLGRIPQAGADNPLSEREMEVLK
LIADGLTNAEIGRRLYIASGTVRVHVSNIIAKLGVNDRVQAAVRALREGWIR
>Mature_211_residues
TRILIVEDHALMRIGLRQVLSQTPEYEVAGEAADGEQALALARSLQPDLVLMDLGLPVMSGTEVTRILKREYPAMRVLAL
TSHDEDESVFGALAAGADGYCLKATAGIASRLLAAVASVRDGAAWLDPDIADRVLRDLGRIPQAGADNPLSEREMEVLKL
IADGLTNAEIGRRLYIASGTVRVHVSNIIAKLGVNDRVQAAVRALREGWIR

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=210, Percent_Identity=37.6190476190476, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1788222, Length=212, Percent_Identity=32.0754716981132, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787473, Length=217, Percent_Identity=37.7880184331797, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1790102, Length=210, Percent_Identity=32.3809523809524, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI1786747, Length=199, Percent_Identity=25.6281407035176, Blast_Score=81, Evalue=4e-17,
Organism=Escherichia coli, GI1788712, Length=192, Percent_Identity=26.5625, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1788546, Length=201, Percent_Identity=26.3681592039801, Blast_Score=71, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22845; Mature: 22713

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRILIVEDHALMRIGLRQVLSQTPEYEVAGEAADGEQALALARSLQPDLVLMDLGLPVM
CCEEEEECCHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCC
SGTEVTRILKREYPAMRVLALTSHDEDESVFGALAAGADGYCLKATAGIASRLLAAVASV
CCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHH
RDGAAWLDPDIADRVLRDLGRIPQAGADNPLSEREMEVLKLIADGLTNAEIGRRLYIASG
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCEEEEECC
TVRVHVSNIIAKLGVNDRVQAAVRALREGWIR
EEEEHHHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TRILIVEDHALMRIGLRQVLSQTPEYEVAGEAADGEQALALARSLQPDLVLMDLGLPVM
CEEEEECCHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCC
SGTEVTRILKREYPAMRVLALTSHDEDESVFGALAAGADGYCLKATAGIASRLLAAVASV
CCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHH
RDGAAWLDPDIADRVLRDLGRIPQAGADNPLSEREMEVLKLIADGLTNAEIGRRLYIASG
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCEEEEECC
TVRVHVSNIIAKLGVNDRVQAAVRALREGWIR
EEEEHHHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]