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The map label for this gene is yhdP [H]

Identifier: 37520354

GI number: 37520354

Start: 837493

End: 838926

Strand: Direct

Name: yhdP [H]

Synonym: glr0785

Alternate gene names: 37520354

Gene position: 837493-838926 (Clockwise)

Preceding gene: 37520353

Following gene: 37520355

Centisome position: 17.98

GC content: 60.74

Gene sequence:

>1434_bases
ATGGCGGAACCCCCTTTATTGTTGATGGCCGCGACGGCGGGCGAGTTGTTGCTGTCGTGGCCTGAAATGCTCTTGCGGCT
GGCTGCGGTCGTCCTGCTTGTTCTGCTGAACGGGTTTTTCGTAGCCACCGAATTTTCGTTGGTCTCGGTGCGCCGCACCC
GCATCGAACAGCTGGTCGAGGAGGGCGACCGCGGCGCGCTCTCGGTGCAGCGCTCCCAAAAGGACCTCGATCGCTATTTA
TCGGCCACCCAACTCGGGATCACGATCGCCTCGCTGGCTCTGGGCTGGATCGGCGAAGGCACGATCGCCGCCTTGATCGA
GCCCATCTTGAGCGGTTTCTCGATCGCGGCCGGTTCGGCCCTCGCCCACACGATCAGCACGATTGTCGCCTTTTTGTTGA
TCACCTACATGCACATCGTGCTGGGGGAACTGGCTCCCAAGTCGGTGGCCATCCTCTACCCGGAGCGCACGGCACTGCTC
TTCGCTTGGCCCAACGAGATTTTTTTTAAACTCTTCGCGCCGTTTTTGAGCTTTCTCAACTGGTCGTCGTGGTTGGTGCT
GCGCGCCTTTGGGGTAAAGGCCAACGTCAACACCCACACCAACCCGATTGGCCCCGAGGAGTTGCAGTTGCTGATCTCTT
CCTCGAGCGCGTCGGGTCTCGATAAAGGCGAGCAGGAACTGCTCGAAAATGTCTTCGAGTTCGGAGACGCGGTGGCCATC
GATGTGATGGTGCCGCGCACCTCCATCGACGCGCTGCCTTTCACCGCCACCATCCAGGAGGTGCTCTTCGAGGTCTCCCG
CACCGGCCACTCGCGCTACCCGCTCTACGAGGACTCCCTCGACACAATCAAGGGCCAGGTCTCGATCAAGGATGTGATCA
CTCCCCTGGCCAAAGGCGAAGTGCAGCCCACGGACACCGTGGGCGGTCTGGCCCGGCCGATTCTGTTTGTGCCCGAAAAT
AAGCGCATCAGCGAACTGCTCACCCAGATGCAGCGCGAGCGCCAGGCGATGGTGATCGTGGTGGACGAATTCGGCGGGAC
CGCCGGACTGCTGACGATGGAGAACCTGCTCGAAGAACTGGTGGGCAACATCACCGACGAAAGCGATCAGGCGACTCCCG
ACATCGTCAAACTCGACGAGCGTACCGCGATCATCCAGGCGCAGATCAACCTGGAGGAACTGAACGATTTTCTGGACCTC
CAACTGCCCATCTCCGACGAGTACAAGACCCTGGGCGGCTTTGTCATGTACCAGTTGCACAAAGTCCCCGAAGCGGGCGA
GCAGTTCTTCTACAACGAACTCGAATTTACGGTCCTGGAGATGGAGGGACCGCGCCTGGAGCGGGTGCGCTTGGTGTGGC
GCACCCGCGAAGAGGTCGAGGCGGCGGAGCGCTCGATTGCGCGCGAAGCGCAGGCCAACGAAATCGGCAGATAA

Upstream 100 bases:

>100_bases
GAGTGACGGCTCACAAACGTTGGCGAATCTGCTACAACTGAAGCTAGTAGCAAGGAATATGTGCCATGGCGACCGCGTCG
CCTGAGCAGCACCAGCTTTT

Downstream 100 bases:

>100_bases
GCCTGCATATCTATTTCTTTTGCCCGCAGCAAAAATTTACCTGGGCTGTCTGTATTCGTCCAGTGGGCGAGGGTGGCGGA
TGCTAACGTAAATGGAACAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 476

Protein sequence:

>477_residues
MAEPPLLLMAATAGELLLSWPEMLLRLAAVVLLVLLNGFFVATEFSLVSVRRTRIEQLVEEGDRGALSVQRSQKDLDRYL
SATQLGITIASLALGWIGEGTIAALIEPILSGFSIAAGSALAHTISTIVAFLLITYMHIVLGELAPKSVAILYPERTALL
FAWPNEIFFKLFAPFLSFLNWSSWLVLRAFGVKANVNTHTNPIGPEELQLLISSSSASGLDKGEQELLENVFEFGDAVAI
DVMVPRTSIDALPFTATIQEVLFEVSRTGHSRYPLYEDSLDTIKGQVSIKDVITPLAKGEVQPTDTVGGLARPILFVPEN
KRISELLTQMQRERQAMVIVVDEFGGTAGLLTMENLLEELVGNITDESDQATPDIVKLDERTAIIQAQINLEELNDFLDL
QLPISDEYKTLGGFVMYQLHKVPEAGEQFFYNELEFTVLEMEGPRLERVRLVWRTREEVEAAERSIAREAQANEIGR

Sequences:

>Translated_477_residues
MAEPPLLLMAATAGELLLSWPEMLLRLAAVVLLVLLNGFFVATEFSLVSVRRTRIEQLVEEGDRGALSVQRSQKDLDRYL
SATQLGITIASLALGWIGEGTIAALIEPILSGFSIAAGSALAHTISTIVAFLLITYMHIVLGELAPKSVAILYPERTALL
FAWPNEIFFKLFAPFLSFLNWSSWLVLRAFGVKANVNTHTNPIGPEELQLLISSSSASGLDKGEQELLENVFEFGDAVAI
DVMVPRTSIDALPFTATIQEVLFEVSRTGHSRYPLYEDSLDTIKGQVSIKDVITPLAKGEVQPTDTVGGLARPILFVPEN
KRISELLTQMQRERQAMVIVVDEFGGTAGLLTMENLLEELVGNITDESDQATPDIVKLDERTAIIQAQINLEELNDFLDL
QLPISDEYKTLGGFVMYQLHKVPEAGEQFFYNELEFTVLEMEGPRLERVRLVWRTREEVEAAERSIAREAQANEIGR
>Mature_476_residues
AEPPLLLMAATAGELLLSWPEMLLRLAAVVLLVLLNGFFVATEFSLVSVRRTRIEQLVEEGDRGALSVQRSQKDLDRYLS
ATQLGITIASLALGWIGEGTIAALIEPILSGFSIAAGSALAHTISTIVAFLLITYMHIVLGELAPKSVAILYPERTALLF
AWPNEIFFKLFAPFLSFLNWSSWLVLRAFGVKANVNTHTNPIGPEELQLLISSSSASGLDKGEQELLENVFEFGDAVAID
VMVPRTSIDALPFTATIQEVLFEVSRTGHSRYPLYEDSLDTIKGQVSIKDVITPLAKGEVQPTDTVGGLARPILFVPENK
RISELLTQMQRERQAMVIVVDEFGGTAGLLTMENLLEELVGNITDESDQATPDIVKLDERTAIIQAQINLEELNDFLDLQ
LPISDEYKTLGGFVMYQLHKVPEAGEQFFYNELEFTVLEMEGPRLERVRLVWRTREEVEAAERSIAREAQANEIGR

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=383, Percent_Identity=39.686684073107, Blast_Score=271, Evalue=1e-72,
Organism=Escherichia coli, GI145693175, Length=423, Percent_Identity=25.0591016548463, Blast_Score=159, Evalue=5e-40,
Organism=Escherichia coli, GI1790664, Length=441, Percent_Identity=24.4897959183673, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1786879, Length=255, Percent_Identity=30.1960784313725, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI87082033, Length=250, Percent_Identity=24.4, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788119, Length=269, Percent_Identity=25.6505576208178, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 52817; Mature: 52685

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEPPLLLMAATAGELLLSWPEMLLRLAAVVLLVLLNGFFVATEFSLVSVRRTRIEQLVE
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
EGDRGALSVQRSQKDLDRYLSATQLGITIASLALGWIGEGTIAALIEPILSGFSIAAGSA
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHCCHH
LAHTISTIVAFLLITYMHIVLGELAPKSVAILYPERTALLFAWPNEIFFKLFAPFLSFLN
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHHHC
WSSWLVLRAFGVKANVNTHTNPIGPEELQLLISSSSASGLDKGEQELLENVFEFGDAVAI
CCHHHHHHEECCEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEE
DVMVPRTSIDALPFTATIQEVLFEVSRTGHSRYPLYEDSLDTIKGQVSIKDVITPLAKGE
EEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCEEHHHHHHHHHCCC
VQPTDTVGGLARPILFVPENKRISELLTQMQRERQAMVIVVDEFGGTAGLLTMENLLEEL
CCCCHHHHHHHCCEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHH
VGNITDESDQATPDIVKLDERTAIIQAQINLEELNDFLDLQLPISDEYKTLGGFVMYQLH
HHCCCCCCCCCCCCCEEECCCEEEEEEECCHHHHHHHHEEECCCCCCHHHHHHHHHHHHH
KVPEAGEQFFYNELEFTVLEMEGPRLERVRLVWRTREEVEAAERSIAREAQANEIGR
HCCCHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AEPPLLLMAATAGELLLSWPEMLLRLAAVVLLVLLNGFFVATEFSLVSVRRTRIEQLVE
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
EGDRGALSVQRSQKDLDRYLSATQLGITIASLALGWIGEGTIAALIEPILSGFSIAAGSA
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHCCHH
LAHTISTIVAFLLITYMHIVLGELAPKSVAILYPERTALLFAWPNEIFFKLFAPFLSFLN
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHHHC
WSSWLVLRAFGVKANVNTHTNPIGPEELQLLISSSSASGLDKGEQELLENVFEFGDAVAI
CCHHHHHHEECCEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEE
DVMVPRTSIDALPFTATIQEVLFEVSRTGHSRYPLYEDSLDTIKGQVSIKDVITPLAKGE
EEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCEEHHHHHHHHHCCC
VQPTDTVGGLARPILFVPENKRISELLTQMQRERQAMVIVVDEFGGTAGLLTMENLLEEL
CCCCHHHHHHHCCEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHH
VGNITDESDQATPDIVKLDERTAIIQAQINLEELNDFLDLQLPISDEYKTLGGFVMYQLH
HHCCCCCCCCCCCCCEEECCCEEEEEEECCHHHHHHHHEEECCCCCCHHHHHHHHHHHHH
KVPEAGEQFFYNELEFTVLEMEGPRLERVRLVWRTREEVEAAERSIAREAQANEIGR
HCCCHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]