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The map label for this gene is sds [H]

Identifier: 37520322

GI number: 37520322

Start: 803020

End: 803997

Strand: Reverse

Name: sds [H]

Synonym: gvip084

Alternate gene names: 37520322

Gene position: 803997-803020 (Counterclockwise)

Preceding gene: 37520323

Following gene: 37520321

Centisome position: 17.26

GC content: 64.01

Gene sequence:

>978_bases
ATGAGCGTGGTGTCCGCAGCGAACTGGTCGGCCCTGGTCGAAGACGACTTAAGCCAGATGACGCGCAATTTGAAGAATCT
GCTGGGGACGAAGCATCCGGTTCTGTATGCAGCGGCTGAGCACCTGTTCAACGCGGGCGGCAAGCGCATCCGCCCGGCGC
TGGTGCTTTTGGTCTCGCGGGCGACGGCGGCCTACGGCGAGCCGACCGAGCGGCACCGCCGTCTGGCTGAAATTACCGAG
ATGATCCACACTGCGTCGCTGGTGCACGACGATGTCATCGACACCAGCGCCGTGCGCCGCGGCATCGACACGGTCAATTC
CCGCTTCGGCAACCGGGTGGCGGTGCTGGCGGGGGACTATTTGTTCGGGATGGCCTCGGCCTACCTGGCCCGCCTGGGCA
GCCTGGAGGTGGTCGAGCTGTTGGGAATTGTCATCTCGCACTTCGGCGAGGGCGAACTGTTGCAGAGCACGCTGCAGTTC
GACTCGGACCTGACCTTCGAGCAGTACATCGACAAGAGCTTTTATAAGACCGCTTCGTTGATGGCAGGCACTTCGAGGGC
GGCGGCGGTGCTCTCCGAGAGCCCAGCGGCCGTCTGCGAAGCGCTCTACGAGTACGGTCGCCACCTGGGCATCGCCTTTC
AGGTAATCGACGACCTGCTGGATTTCACTGGTTCGACCGCCAAACTGGGCAAACCCGCCGGTTCGGACCTGCGCGACGGC
AATCTCACCGCCCCGGTGCTCTACGCCCTCGAAGAGTCGCCTCACCTGAGCGGCCTCATCGAGCGCCAGTTCGAGCAGAA
GGGCGATCTTGAAAAGGCCCTTTCGCTGATCCATGCCAGCCGTGCGCTGGAGCGCACCCGCGAGCTTGCAGAAACCCACG
CCCGCCGGGCGGTGACCTCTCTCGACACTCTCTCCCCCTCCCCGGCGCGCGAAGCGCTCAAAGATTTGGTCGGACACACC
GTCAGCCGGCTGTACTGA

Upstream 100 bases:

>100_bases
CTTTGCGATGGAACGTGACTGCGGCGAATAGACGCGGGCGGTTTATGATTAATGATGAAGGCACTGTTACCTTTCTTAAT
TTCAGTGCGCAGCTGGAGAA

Downstream 100 bases:

>100_bases
TGGGCCGTGTTTGTAATGGCCTCGCCAGAATCCGAAATCTATCTTAAAATTGGGGCCAGTACGGACGGTCACGCAGCGGT
TCTGGTTGGAACCGGAAGGC

Product: solanesyl diphosphate synthase

Products: trans-polyisoprenyln-PP; pyrophosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MSVVSAANWSALVEDDLSQMTRNLKNLLGTKHPVLYAAAEHLFNAGGKRIRPALVLLVSRATAAYGEPTERHRRLAEITE
MIHTASLVHDDVIDTSAVRRGIDTVNSRFGNRVAVLAGDYLFGMASAYLARLGSLEVVELLGIVISHFGEGELLQSTLQF
DSDLTFEQYIDKSFYKTASLMAGTSRAAAVLSESPAAVCEALYEYGRHLGIAFQVIDDLLDFTGSTAKLGKPAGSDLRDG
NLTAPVLYALEESPHLSGLIERQFEQKGDLEKALSLIHASRALERTRELAETHARRAVTSLDTLSPSPAREALKDLVGHT
VSRLY

Sequences:

>Translated_325_residues
MSVVSAANWSALVEDDLSQMTRNLKNLLGTKHPVLYAAAEHLFNAGGKRIRPALVLLVSRATAAYGEPTERHRRLAEITE
MIHTASLVHDDVIDTSAVRRGIDTVNSRFGNRVAVLAGDYLFGMASAYLARLGSLEVVELLGIVISHFGEGELLQSTLQF
DSDLTFEQYIDKSFYKTASLMAGTSRAAAVLSESPAAVCEALYEYGRHLGIAFQVIDDLLDFTGSTAKLGKPAGSDLRDG
NLTAPVLYALEESPHLSGLIERQFEQKGDLEKALSLIHASRALERTRELAETHARRAVTSLDTLSPSPAREALKDLVGHT
VSRLY
>Mature_324_residues
SVVSAANWSALVEDDLSQMTRNLKNLLGTKHPVLYAAAEHLFNAGGKRIRPALVLLVSRATAAYGEPTERHRRLAEITEM
IHTASLVHDDVIDTSAVRRGIDTVNSRFGNRVAVLAGDYLFGMASAYLARLGSLEVVELLGIVISHFGEGELLQSTLQFD
SDLTFEQYIDKSFYKTASLMAGTSRAAAVLSESPAAVCEALYEYGRHLGIAFQVIDDLLDFTGSTAKLGKPAGSDLRDGN
LTAPVLYALEESPHLSGLIERQFEQKGDLEKALSLIHASRALERTRELAETHARRAVTSLDTLSPSPAREALKDLVGHTV
SRLY

Specific function: Possible role in synthesis of the nonaprenyl side chain of plastoquinone or in synthesis of other prenyl chains such as undekaprenyl pyrophosphate [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=306, Percent_Identity=39.8692810457516, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI169808399, Length=329, Percent_Identity=27.355623100304, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI4758430, Length=285, Percent_Identity=23.859649122807, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI83700220, Length=285, Percent_Identity=23.859649122807, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1789578, Length=287, Percent_Identity=38.6759581881533, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI1786623, Length=220, Percent_Identity=31.8181818181818, Blast_Score=75, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17505681, Length=314, Percent_Identity=36.9426751592357, Blast_Score=198, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6319475, Length=298, Percent_Identity=40.6040268456376, Blast_Score=213, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6325188, Length=221, Percent_Identity=25.3393665158371, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24651612, Length=321, Percent_Identity=37.6947040498442, Blast_Score=232, Evalue=3e-61,
Organism=Drosophila melanogaster, GI21356309, Length=361, Percent_Identity=27.7008310249307, Blast_Score=115, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR014120
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: 2.5.1.- [C]

Molecular weight: Translated: 35364; Mature: 35232

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVVSAANWSALVEDDLSQMTRNLKNLLGTKHPVLYAAAEHLFNAGGKRIRPALVLLVSR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ATAAYGEPTERHRRLAEITEMIHTASLVHDDVIDTSAVRRGIDTVNSRFGNRVAVLAGDY
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHH
LFGMASAYLARLGSLEVVELLGIVISHFGEGELLQSTLQFDSDLTFEQYIDKSFYKTASL
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
MAGTSRAAAVLSESPAAVCEALYEYGRHLGIAFQVIDDLLDFTGSTAKLGKPAGSDLRDG
HHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
NLTAPVLYALEESPHLSGLIERQFEQKGDLEKALSLIHASRALERTRELAETHARRAVTS
CCCHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDTLSPSPAREALKDLVGHTVSRLY
HHCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVVSAANWSALVEDDLSQMTRNLKNLLGTKHPVLYAAAEHLFNAGGKRIRPALVLLVSR
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ATAAYGEPTERHRRLAEITEMIHTASLVHDDVIDTSAVRRGIDTVNSRFGNRVAVLAGDY
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHH
LFGMASAYLARLGSLEVVELLGIVISHFGEGELLQSTLQFDSDLTFEQYIDKSFYKTASL
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
MAGTSRAAAVLSESPAAVCEALYEYGRHLGIAFQVIDDLLDFTGSTAKLGKPAGSDLRDG
HHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
NLTAPVLYALEESPHLSGLIERQFEQKGDLEKALSLIHASRALERTRELAETHARRAVTS
CCCHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDTLSPSPAREALKDLVGHTVSRLY
HHCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: trans-polyisoprenyln-PP; Delta3-isopentenyl-PP [C]

Specific reaction: trans-polyisoprenyln-PP + Delta3-isopentenyl-PP = trans-polyisoprenyln-PP + pyrophosphate [C]

General reaction: Transferring alkyl or aryl groups, other than methyl groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]