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The map label for this gene is fda [H]

Identifier: 37520321

GI number: 37520321

Start: 801832

End: 802902

Strand: Reverse

Name: fda [H]

Synonym: gvip083

Alternate gene names: 37520321

Gene position: 802902-801832 (Counterclockwise)

Preceding gene: 37520322

Following gene: 37520315

Centisome position: 17.23

GC content: 62.18

Gene sequence:

>1071_bases
ATGGCGCTTGTACCGTTGAGGGTTTTGCTGGATCACGCCGCTGAAAACAACTATGGCATTCCGGCGTTCAACGTCAACAA
CCTCGAACAAATCAAGGCGATCATGGACGCCGCCCGCGAAGTGAACAGCCCCGTCATCCTGCAGGCGTCGCGCGGCGCCC
GCAAATACGCGGGTGAAGCGTTCCTGCGCCACATGGTGCTTGCGGCGGTCGAAGAATACCCCGAGATTCCGATCGTCATG
CACCAGGACCACGGCAACAGCCCGGCCACCTGCTACTCGGCCATCAAGAACGGCTTTACGAGCGTGATGATGGACGGTTC
GCTGATGGAAGACGCAAAGACCCCGGCGAGCTACGAATACAACGTCGAGGTGACCGCCAAGGTGACCGAGGTGGCCCACG
CTCTGGGTGTGAGCGTCGAAGGTGAACTCGGCTGCCTCGGTTCGCTCGAGACCGGCGCCGGCGACAAAGAGGACGGCCAC
GGCTTCGAGGGCACCCTCTCCCACGACCAGCTTTTGACCGACCCGGATGAGGCGGCCGATTTCGTCGAGCGCACCGGCGT
CGACGCCCTCGCCATCGCCATCGGCACCAGCCACGGCGCCTACAAGTTCAGCCGCAAGCCCGACGGCGCCATCCTCGCCA
TCGACCGCATCCGCGAAATCCACCGCAGGCTCCCCAACACCCACCTGGTCATGCACGGTTCTTCGAGCGTGCCCCAGGAT
CTCCAAGACCTGATTAATGCCCACGGCGGCGCCATTCCCCAGACCTGGGGAGTACCGGTGACCGAGATTCAAGAAGGCAT
CCGCAACGGCGTGCGCAAGGTCAATGTCGATACCGACAACCGCCTGGCGATCACCGCTGCGGTGCGCGAAGCCCTCGCTA
AAGAACCCGCCGAGTTCGACCCGCGCAAGTTCTTGATTCCTTCGATGAAGTATATGCTGAAGGTCTGCCGCGACCGCTAC
GTCGAGTTCGGCTCCGCCGAGCAGGCGAGCAAAATCAAGCAGGTCTCCCTCGATGAGATGGCCAAGCGCTACATCGCCGC
AAGCACCATGAAAAAGGCCGTCACGGTCTAA

Upstream 100 bases:

>100_bases
GGCCTCGCCAGAATCCGAAATCTATCTTAAAATTGGGGCCAGTACGGACGGTCACGCAGCGGTTCTGGTTGGAACCGGAA
GGCACATCTAGGAGGAAATT

Downstream 100 bases:

>100_bases
CAGCTGTACCACTTAAGCACCAAAAAGGGGCTGATTCTCGGCCCCTTTTTGTTTGCGGTACTGCCGACAAAATGCCGGTA
TGTAAGTCCGCACCTGGGCG

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MALVPLRVLLDHAAENNYGIPAFNVNNLEQIKAIMDAAREVNSPVILQASRGARKYAGEAFLRHMVLAAVEEYPEIPIVM
HQDHGNSPATCYSAIKNGFTSVMMDGSLMEDAKTPASYEYNVEVTAKVTEVAHALGVSVEGELGCLGSLETGAGDKEDGH
GFEGTLSHDQLLTDPDEAADFVERTGVDALAIAIGTSHGAYKFSRKPDGAILAIDRIREIHRRLPNTHLVMHGSSSVPQD
LQDLINAHGGAIPQTWGVPVTEIQEGIRNGVRKVNVDTDNRLAITAAVREALAKEPAEFDPRKFLIPSMKYMLKVCRDRY
VEFGSAEQASKIKQVSLDEMAKRYIAASTMKKAVTV

Sequences:

>Translated_356_residues
MALVPLRVLLDHAAENNYGIPAFNVNNLEQIKAIMDAAREVNSPVILQASRGARKYAGEAFLRHMVLAAVEEYPEIPIVM
HQDHGNSPATCYSAIKNGFTSVMMDGSLMEDAKTPASYEYNVEVTAKVTEVAHALGVSVEGELGCLGSLETGAGDKEDGH
GFEGTLSHDQLLTDPDEAADFVERTGVDALAIAIGTSHGAYKFSRKPDGAILAIDRIREIHRRLPNTHLVMHGSSSVPQD
LQDLINAHGGAIPQTWGVPVTEIQEGIRNGVRKVNVDTDNRLAITAAVREALAKEPAEFDPRKFLIPSMKYMLKVCRDRY
VEFGSAEQASKIKQVSLDEMAKRYIAASTMKKAVTV
>Mature_355_residues
ALVPLRVLLDHAAENNYGIPAFNVNNLEQIKAIMDAAREVNSPVILQASRGARKYAGEAFLRHMVLAAVEEYPEIPIVMH
QDHGNSPATCYSAIKNGFTSVMMDGSLMEDAKTPASYEYNVEVTAKVTEVAHALGVSVEGELGCLGSLETGAGDKEDGHG
FEGTLSHDQLLTDPDEAADFVERTGVDALAIAIGTSHGAYKFSRKPDGAILAIDRIREIHRRLPNTHLVMHGSSSVPQDL
QDLINAHGGAIPQTWGVPVTEIQEGIRNGVRKVNVDTDNRLAITAAVREALAKEPAEFDPRKFLIPSMKYMLKVCRDRYV
EFGSAEQASKIKQVSLDEMAKRYIAASTMKKAVTV

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=333, Percent_Identity=33.6336336336336, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI87082041, Length=315, Percent_Identity=30.7936507936508, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1788072, Length=288, Percent_Identity=30.9027777777778, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1789293, Length=309, Percent_Identity=25.8899676375405, Blast_Score=82, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6322790, Length=318, Percent_Identity=26.7295597484277, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006412
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 38706; Mature: 38575

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVPLRVLLDHAAENNYGIPAFNVNNLEQIKAIMDAAREVNSPVILQASRGARKYAGEA
CCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHH
FLRHMVLAAVEEYPEIPIVMHQDHGNSPATCYSAIKNGFTSVMMDGSLMEDAKTPASYEY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCHHHHHCCCHHHHHCCCCCCEEE
NVEVTAKVTEVAHALGVSVEGELGCLGSLETGAGDKEDGHGFEGTLSHDQLLTDPDEAAD
EEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
FVERTGVDALAIAIGTSHGAYKFSRKPDGAILAIDRIREIHRRLPNTHLVMHGSSSVPQD
HHHHCCCCEEEEEEECCCCCEEECCCCCCCEEEHHHHHHHHHHCCCCEEEEECCCCCCHH
LQDLINAHGGAIPQTWGVPVTEIQEGIRNGVRKVNVDTDNRLAITAAVREALAKEPAEFD
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCCEEHHHHHHHHHHCCCCCCC
PRKFLIPSMKYMLKVCRDRYVEFGSAEQASKIKQVSLDEMAKRYIAASTMKKAVTV
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALVPLRVLLDHAAENNYGIPAFNVNNLEQIKAIMDAAREVNSPVILQASRGARKYAGEA
CCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHH
FLRHMVLAAVEEYPEIPIVMHQDHGNSPATCYSAIKNGFTSVMMDGSLMEDAKTPASYEY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCHHHHHCCCHHHHHCCCCCCEEE
NVEVTAKVTEVAHALGVSVEGELGCLGSLETGAGDKEDGHGFEGTLSHDQLLTDPDEAAD
EEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
FVERTGVDALAIAIGTSHGAYKFSRKPDGAILAIDRIREIHRRLPNTHLVMHGSSSVPQD
HHHHCCCCEEEEEEECCCCCEEECCCCCCCEEEHHHHHHHHHHCCCCEEEEECCCCCCHH
LQDLINAHGGAIPQTWGVPVTEIQEGIRNGVRKVNVDTDNRLAITAAVREALAKEPAEFD
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCCEEHHHHHHHHHHCCCCCCC
PRKFLIPSMKYMLKVCRDRYVEFGSAEQASKIKQVSLDEMAKRYIAASTMKKAVTV
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA