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The map label for this gene is degU [H]

Identifier: 37520140

GI number: 37520140

Start: 608894

End: 609547

Strand: Reverse

Name: degU [H]

Synonym: gll0571

Alternate gene names: 37520140

Gene position: 609547-608894 (Counterclockwise)

Preceding gene: 37520141

Following gene: 37520139

Centisome position: 13.08

GC content: 68.96

Gene sequence:

>654_bases
ATGAGCGGGAGGGTGCGTGTGCTACTCGTCGAGGATGACCCGCTTTTTCGGATGGGCCTCGCCATGGTCCTGCGCCACCA
GCCGCAGATCGAGCTGGTGGCCGAGGCGGAGGACGGTGAGACCGCCCTTGCGCTGGCGAATCGCCACCGACCGCAATTGG
TGCTGCTTGACATCGGCCTGCCGGGTCTGGACGGCCGGCAGACCCTCGTTCGCCTCAAGCAGGAGCACCCCGAAATCCGG
GTACTGGTACTCACCTCGCGCGAGGAGGCCGGTTTGGTGCAGGCCATGCTGCAGGCGGGGGCGGACGGTTACTGCCTGAA
GGGGATCGGCCCGGATCGGTTGCTCACGGTGATCCGCGAGGTGAGCGCCGGCAACGGCTGGTTCGACGCCAAGGTGCTCG
CCCAGGTGCGCAGCGCCTTCGCCGTCGCCCCCTCCGAGCCGCCCGCCAACGCCGCCGCCCTCACCGAGCGCGAGCGGGAG
GTACTGGGCTGGATCGCCCGGGGGGCGAGCAACCCCGAGATCGGCCGACAGCTCCATATCTCCAGCGGCACCGTGCGGGT
GCACGTCCACGCCATCCTGCGCAAGCTCGGGGCGACCGATCGCACCCAGGCTGCCGTCCTTGCCCTCGAAAAGGGTTTGA
TCGCTCCTCCTTAA

Upstream 100 bases:

>100_bases
TCTGGGCGGCGAACCGGCCGGGGGGCGGTTGTCTGTTTGGGGTGAGCCTGCCCGACTCGGTGCCGCCGGGTGCCGCAGCC
CTCGCCCGGAGCGCTGCAAG

Downstream 100 bases:

>100_bases
CCGTAACTGTGGGTCGCCATGTTCCGCCCGAACGAAGACTGTCCTGATCCCCAGTCGTTGCTGCACGAGCTGATGCAGCT
GTCGCGGGGTCGCCTGAAGC

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MSGRVRVLLVEDDPLFRMGLAMVLRHQPQIELVAEAEDGETALALANRHRPQLVLLDIGLPGLDGRQTLVRLKQEHPEIR
VLVLTSREEAGLVQAMLQAGADGYCLKGIGPDRLLTVIREVSAGNGWFDAKVLAQVRSAFAVAPSEPPANAAALTERERE
VLGWIARGASNPEIGRQLHISSGTVRVHVHAILRKLGATDRTQAAVLALEKGLIAPP

Sequences:

>Translated_217_residues
MSGRVRVLLVEDDPLFRMGLAMVLRHQPQIELVAEAEDGETALALANRHRPQLVLLDIGLPGLDGRQTLVRLKQEHPEIR
VLVLTSREEAGLVQAMLQAGADGYCLKGIGPDRLLTVIREVSAGNGWFDAKVLAQVRSAFAVAPSEPPANAAALTERERE
VLGWIARGASNPEIGRQLHISSGTVRVHVHAILRKLGATDRTQAAVLALEKGLIAPP
>Mature_216_residues
SGRVRVLLVEDDPLFRMGLAMVLRHQPQIELVAEAEDGETALALANRHRPQLVLLDIGLPGLDGRQTLVRLKQEHPEIRV
LVLTSREEAGLVQAMLQAGADGYCLKGIGPDRLLTVIREVSAGNGWFDAKVLAQVRSAFAVAPSEPPANAAALTEREREV
LGWIARGASNPEIGRQLHISSGTVRVHVHAILRKLGATDRTQAAVLALEKGLIAPP

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=206, Percent_Identity=38.3495145631068, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1788222, Length=209, Percent_Identity=30.1435406698565, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787473, Length=201, Percent_Identity=34.8258706467662, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1786747, Length=192, Percent_Identity=29.1666666666667, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1790102, Length=201, Percent_Identity=28.8557213930348, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1788712, Length=192, Percent_Identity=21.875, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23418; Mature: 23286

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRVRVLLVEDDPLFRMGLAMVLRHQPQIELVAEAEDGETALALANRHRPQLVLLDIGL
CCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCCCCEEEEEECCC
PGLDGRQTLVRLKQEHPEIRVLVLTSREEAGLVQAMLQAGADGYCLKGIGPDRLLTVIRE
CCCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHH
VSAGNGWFDAKVLAQVRSAFAVAPSEPPANAAALTEREREVLGWIARGASNPEIGRQLHI
HCCCCCCHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
SSGTVRVHVHAILRKLGATDRTQAAVLALEKGLIAPP
CCCEEEEEHHHHHHHHCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SGRVRVLLVEDDPLFRMGLAMVLRHQPQIELVAEAEDGETALALANRHRPQLVLLDIGL
CCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCCCCEEEEEECCC
PGLDGRQTLVRLKQEHPEIRVLVLTSREEAGLVQAMLQAGADGYCLKGIGPDRLLTVIRE
CCCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHH
VSAGNGWFDAKVLAQVRSAFAVAPSEPPANAAALTEREREVLGWIARGASNPEIGRQLHI
HCCCCCCHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
SSGTVRVHVHAILRKLGATDRTQAAVLALEKGLIAPP
CCCEEEEEHHHHHHHHCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]