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The map label for this gene is hoxX [H]

Identifier: 34499597

GI number: 34499597

Start: 4481738

End: 4483435

Strand: Reverse

Name: hoxX [H]

Synonym: CV_4142

Alternate gene names: 34499597

Gene position: 4483435-4481738 (Counterclockwise)

Preceding gene: 34499598

Following gene: 34499596

Centisome position: 94.37

GC content: 70.2

Gene sequence:

>1698_bases
GTGCAAGCCCTGAGAATCGTCTTGTTGTCCACCGCCTTCAACGGCCTGACCCAGCGCGCCTGGCTGGACCTGAGGGAGTC
CGGCCACGACCCCAGCGTGGTGCTGTTCACCGACGCCGACGAGGTGGCGCGCAAGGTGCGGCAGGCGGAGCCGCAGCTGG
TGATCTGCCCCTTTTTGAAGGACAGGGTGCCGGCCGAGTTGTGGCGCGACAGTCCTTTCCCGGTGGTGATCATCCATCCG
GGCATCGTCGGCGACCGCGGCGCGTCGGCGCTGGACTGGGCGATCATGAAAGGGGAAAAGCGCTGGGGCGTGACCGCCTT
GCAGGCGGTTGAGGAAATGGATGCCGGGCCGGTATGGTCCAGCCGCGAGTTCGAGCTGCCGCGCGGCATCCGCAAGTCCG
AGCTCTACAACGGCCCGGTCAGCGACGCCGCGATGTACTGCATACGCGACGTAGTGGAAAAGTTCGCCGGCGGCTACCAG
CCGCAGGCCGTCGATTACGCCGATCCGCAAGTGGGCGGGAGGCTGCAGCCGAACATGAAACAGGCCGACCGCGCCTTCGA
CTGGCGCGCGCCCGCGGCCGAGATCAAGCGCCGCATCGACGCCGCCGACGGCCAGCCCGGCGTGCTGGCGGATTTGGCCG
GCGGCCGCTACTACGTGTACGACGCCCATCTGGATCATCGCAGCGGCGAGCCGGGCCGCATCCTGGCGGTGCACGACGAC
GCCGCGCTGGTGGCCTGCGGCGACGCCAGCCTGTGGATAGGATCGCTGCGGCGGCAGCCCGCGCCGGGCGAGGAAACCTT
CAAGCGGCCGGCCCGCCATGAACTGGGCGGCCTGCTGGACGGCGTGCCCCGGCTTGAGTGGGCGGTGGACACCCACCCGC
ACTGCGAGGAGAGCTACCAGCCCATCCGCTACCGAGAGGCGGGCCGGGTCGGCGAGCTGACCTTCGAGTTCTACAACGGC
GCGCTCAGCACCGAGCAGTGCCAGCGCCTGGTGCGCGCCCTGCAGTGGGCGAAGCGCCGGGACACCCAGGTGCTGCTGGT
GCGCAGCGGCCGCGGCAGCTTCTGCAACGGCATCCATCTCAATGTGATCCAGGCGGCCGATCATCCGGGCGAGGAGGCAT
GGCGCAACATCCAGGCGATAGACGACGTCTGCCTGGAAATCCTGACCGCGCCGCAACTGACGGTGGCCGGCGTGGCCGGC
AACGCCGGCGCCGGCGGCGTGATGCTGGCGCTGGCCGCCGACGTGGCGCTGGCGCGCCAGGGCGTGGTGCTGAACCCGCA
TTACCAGACCATGGGCCTGTACGGCTCGGAGTACTGGACTTACACGTTGCCGCGCGCGGTGGGCGGTGAGATGGCCGCCA
GGCTGTGCGGCGATTGCCTGCCGATCGGCGCGCGCCAGGCCTGGCGGCTGGGCATGGTGCAGGATATCGGCCCGCGCGAT
CCCGACGCCTTCGGTAGCTGGCTGCTGAGCACGGCCGCGGCGGCTGAGCGCACCTGGCCGGAGCATGCCCGTCGCAAGCA
GGAGCTTGACCTGGGCCGGCTGCAGCAATGCCGGCGGGCTGAGCTCGACGAGATGCGCGAGGACATGCTGGAAAACCGCC
GCCAGTTCGCCGAGCGCTGCCGCAATTTCGTGTTGAAACGCCCCGCCTGCGGCACGCCGGACAGGCTGGTGGCCGGCTGG
GCTCGGGCGGACGGCTAG

Upstream 100 bases:

>100_bases
TTTTATGCCTTGATCATTTAAATTGTCCCCGGTCAAATTGTATTGAATTTCCCTTCCGTAGCATGCGGCGCTTGTCCGAG
TCCATACACGGGAGAACGCA

Downstream 100 bases:

>100_bases
GCTGGGCGTATACTGGAACGCCGAGCGCCGCGCTTTGCGCGGCGTCGATTCGAGCAAGCCGCGTCAAGAATGTGGCGGCG
CGTTCCGGCATAGTGGCCGC

Product: hoxX-like protein

Products: Coenzyme A; 1,4-Dihydroxy-2-naphthoate [C]

Alternate protein names: NA

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MQALRIVLLSTAFNGLTQRAWLDLRESGHDPSVVLFTDADEVARKVRQAEPQLVICPFLKDRVPAELWRDSPFPVVIIHP
GIVGDRGASALDWAIMKGEKRWGVTALQAVEEMDAGPVWSSREFELPRGIRKSELYNGPVSDAAMYCIRDVVEKFAGGYQ
PQAVDYADPQVGGRLQPNMKQADRAFDWRAPAAEIKRRIDAADGQPGVLADLAGGRYYVYDAHLDHRSGEPGRILAVHDD
AALVACGDASLWIGSLRRQPAPGEETFKRPARHELGGLLDGVPRLEWAVDTHPHCEESYQPIRYREAGRVGELTFEFYNG
ALSTEQCQRLVRALQWAKRRDTQVLLVRSGRGSFCNGIHLNVIQAADHPGEEAWRNIQAIDDVCLEILTAPQLTVAGVAG
NAGAGGVMLALAADVALARQGVVLNPHYQTMGLYGSEYWTYTLPRAVGGEMAARLCGDCLPIGARQAWRLGMVQDIGPRD
PDAFGSWLLSTAAAAERTWPEHARRKQELDLGRLQQCRRAELDEMREDMLENRRQFAERCRNFVLKRPACGTPDRLVAGW
ARADG

Sequences:

>Translated_565_residues
MQALRIVLLSTAFNGLTQRAWLDLRESGHDPSVVLFTDADEVARKVRQAEPQLVICPFLKDRVPAELWRDSPFPVVIIHP
GIVGDRGASALDWAIMKGEKRWGVTALQAVEEMDAGPVWSSREFELPRGIRKSELYNGPVSDAAMYCIRDVVEKFAGGYQ
PQAVDYADPQVGGRLQPNMKQADRAFDWRAPAAEIKRRIDAADGQPGVLADLAGGRYYVYDAHLDHRSGEPGRILAVHDD
AALVACGDASLWIGSLRRQPAPGEETFKRPARHELGGLLDGVPRLEWAVDTHPHCEESYQPIRYREAGRVGELTFEFYNG
ALSTEQCQRLVRALQWAKRRDTQVLLVRSGRGSFCNGIHLNVIQAADHPGEEAWRNIQAIDDVCLEILTAPQLTVAGVAG
NAGAGGVMLALAADVALARQGVVLNPHYQTMGLYGSEYWTYTLPRAVGGEMAARLCGDCLPIGARQAWRLGMVQDIGPRD
PDAFGSWLLSTAAAAERTWPEHARRKQELDLGRLQQCRRAELDEMREDMLENRRQFAERCRNFVLKRPACGTPDRLVAGW
ARADG
>Mature_565_residues
MQALRIVLLSTAFNGLTQRAWLDLRESGHDPSVVLFTDADEVARKVRQAEPQLVICPFLKDRVPAELWRDSPFPVVIIHP
GIVGDRGASALDWAIMKGEKRWGVTALQAVEEMDAGPVWSSREFELPRGIRKSELYNGPVSDAAMYCIRDVVEKFAGGYQ
PQAVDYADPQVGGRLQPNMKQADRAFDWRAPAAEIKRRIDAADGQPGVLADLAGGRYYVYDAHLDHRSGEPGRILAVHDD
AALVACGDASLWIGSLRRQPAPGEETFKRPARHELGGLLDGVPRLEWAVDTHPHCEESYQPIRYREAGRVGELTFEFYNG
ALSTEQCQRLVRALQWAKRRDTQVLLVRSGRGSFCNGIHLNVIQAADHPGEEAWRNIQAIDDVCLEILTAPQLTVAGVAG
NAGAGGVMLALAADVALARQGVVLNPHYQTMGLYGSEYWTYTLPRAVGGEMAARLCGDCLPIGARQAWRLGMVQDIGPRD
PDAFGSWLLSTAAAAERTWPEHARRKQELDLGRLQQCRRAELDEMREDMLENRRQFAERCRNFVLKRPACGTPDRLVAGW
ARADG

Specific function: Involved in the post-translational processing of the hydrogenase large subunit [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI238814322, Length=198, Percent_Identity=24.7474747474747, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR015518
- InterPro:   IPR009188 [H]

Pfam domain/function: PF00378 ECH; PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: 4.1.3.36 [C]

Molecular weight: Translated: 62581; Mature: 62581

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQALRIVLLSTAFNGLTQRAWLDLRESGHDPSVVLFTDADEVARKVRQAEPQLVICPFLK
CCHHHEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHCCCCEEEECHHH
DRVPAELWRDSPFPVVIIHPGIVGDRGASALDWAIMKGEKRWGVTALQAVEEMDAGPVWS
CCCCHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCC
SREFELPRGIRKSELYNGPVSDAAMYCIRDVVEKFAGGYQPQAVDYADPQVGGRLQPNMK
CCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
QADRAFDWRAPAAEIKRRIDAADGQPGVLADLAGGRYYVYDAHLDHRSGEPGRILAVHDD
HHHHHCCCCCCHHHHHHHHCCCCCCCCEEEECCCCEEEEEECCCCCCCCCCCEEEEEECC
AALVACGDASLWIGSLRRQPAPGEETFKRPARHELGGLLDGVPRLEWAVDTHPHCEESYQ
CEEEEECCHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHCCCCCCEEEECCCCCCHHCCC
PIRYREAGRVGELTFEFYNGALSTEQCQRLVRALQWAKRRDTQVLLVRSGRGSFCNGIHL
CCHHHCCCCCCEEEHEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEE
NVIQAADHPGEEAWRNIQAIDDVCLEILTAPQLTVAGVAGNAGAGGVMLALAADVALARQ
EEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCC
GVVLNPHYQTMGLYGSEYWTYTLPRAVGGEMAARLCGDCLPIGARQAWRLGMVQDIGPRD
CCEECCCHHHHCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHCCCCC
PDAFGSWLLSTAAAAERTWPEHARRKQELDLGRLQQCRRAELDEMREDMLENRRQFAERC
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNFVLKRPACGTPDRLVAGWARADG
HHHHCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MQALRIVLLSTAFNGLTQRAWLDLRESGHDPSVVLFTDADEVARKVRQAEPQLVICPFLK
CCHHHEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHCCCCEEEECHHH
DRVPAELWRDSPFPVVIIHPGIVGDRGASALDWAIMKGEKRWGVTALQAVEEMDAGPVWS
CCCCHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCC
SREFELPRGIRKSELYNGPVSDAAMYCIRDVVEKFAGGYQPQAVDYADPQVGGRLQPNMK
CCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
QADRAFDWRAPAAEIKRRIDAADGQPGVLADLAGGRYYVYDAHLDHRSGEPGRILAVHDD
HHHHHCCCCCCHHHHHHHHCCCCCCCCEEEECCCCEEEEEECCCCCCCCCCCEEEEEECC
AALVACGDASLWIGSLRRQPAPGEETFKRPARHELGGLLDGVPRLEWAVDTHPHCEESYQ
CEEEEECCHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHCCCCCCEEEECCCCCCHHCCC
PIRYREAGRVGELTFEFYNGALSTEQCQRLVRALQWAKRRDTQVLLVRSGRGSFCNGIHL
CCHHHCCCCCCEEEHEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEE
NVIQAADHPGEEAWRNIQAIDDVCLEILTAPQLTVAGVAGNAGAGGVMLALAADVALARQ
EEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCC
GVVLNPHYQTMGLYGSEYWTYTLPRAVGGEMAARLCGDCLPIGARQAWRLGMVQDIGPRD
CCEECCCHHHHCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHCCCCC
PDAFGSWLLSTAAAAERTWPEHARRKQELDLGRLQQCRRAELDEMREDMLENRRQFAERC
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNFVLKRPACGTPDRLVAGWARADG
HHHHCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: O-Succinylbenzoyl-CoA [C]

Specific reaction: O-Succinylbenzoyl-CoA --> Coenzyme A + 1,4-Dihydroxy-2-naphthoate [C]

General reaction: Carbon-Carbon Lyases; Oxo-Acid-Lyases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8510650; 12597275 [H]