Click here to switch to the map view.

The map label for this gene is glmM

Identifier: 34499250

GI number: 34499250

Start: 4091815

End: 4093152

Strand: Reverse

Name: glmM

Synonym: CV_3795

Alternate gene names: 34499250

Gene position: 4093152-4091815 (Counterclockwise)

Preceding gene: 34499251

Following gene: 34499249

Centisome position: 86.15

GC content: 66.07

Gene sequence:

>1338_bases
ATGAGTCGCAAATATTTCGGCACCGATGGCGTGCGCGGCGAGGTCGGCAAATTTCCGATCACGCCCGAATTCGTGATGAA
GCTGGGTTACGCGGCCGGCCGCGTGCTGGTCAACCATGACCAGGACAGCCGTCCCACCGTGCTGATCGGCAAGGACACCC
GTATTTCCGGTTATATGCTGGAAGCGGCGCTGCAAGCTGGTTTTACCGCCGCCGGCGTCAACGTGCTGTTGACCGGCCCG
TTGCCGACGCCCGGCATCGCCTACCTGACCCGCGCGCTGCGGCTGGAGGCCGGCGTGGTGATCTCCGCCTCGCACAATCC
ATTCCAGGATAACGGCATCAAGTTCTTCGCCGAAGGCGGCAACAAGCTGGACGACGCGTTGGAGCTGGAGATCGAGGCGA
TGCTGGACCAGCCCATGGCCACCAATCCGTCGCTGGAGCTGGGCCGTGCCCGCCGCATCGACGGCGCCGCCGAGCGCTAC
ATCGAATTCTGCAAGAGCACCTTCCCCAACGAGCTCAGCCTGAAGGGCTTGAAGTTGGTGGTCGACTGCGCCAACGGCGC
CACTTACCACATCGCCCCCAAGGTGTTTCACGAGCTGGGGGCCGAGCTGGTGGAGATCGGCTGCGAACCCAACGGCTACA
ACATCAACGACAAGGTGGGCGCCACCTATCCCAAGACCTTGCAGATGGCGGTGCTGGAGCACCAGGCCGACTTCGGCATC
GCGCTGGACGGCGACGGCGACCGCCTGATCATGGTGGACGCCGCCGGCCGCGTCTACGATGGCGACCAGCTGATCTACGT
GATCGCCAAGGCGCGCGCCGCGCGCGGCGAATTGAAGGGCGGCGTGGTCGGCACCGTGATGACCAATATGGCGATGGAGC
TGGCGCTGCAAAAGCAGGGCGTGCCCTTTGGCCGCGCCAAGGTAGGCGACCGCTACGTGCTGGAAATGCTGCATGCGGAC
GGCTGGCAGGTGGGCGGCGAGGCGTCCGGCCATATTCTTTGCCTGGACAAGCACAGCACCGGCGACGGCATCATTTCCAG
CCTGCAGGTGCTGGCCAGCCTGAAGCAGCTGGGCTTGAGCCTGGCCGAGATCTGCGCCGACTGGCGGCCATTCCCGCAGA
CGCTGATCAATGTGCGCCACAACGGCTGCGACTGGAAGGCCGCCTCGGCGGCGCCGCTGGCCGAGGCCGAGGCCGCGCTG
CAGGGCCGCGGCCGCGTGGTGTTGCGCCCATCCGGCACCGAGCCGGTGGTGCGGGTGATGGTGGAGGCCGACGACAAGGC
CCTGGCCGACACCTGGGCGAAAGCCATTGCCGCGGCGATCGAGAAAGTCTCTGCCTGA

Upstream 100 bases:

>100_bases
GCGGGATTCTTGATTTGAAGCTGGTTTTCCACCCGGCGGTGGTGGCAAAATGGCGGGCATCGAGCCTGTCAAGGCATTGA
ACCGATACAGAGAATACTGA

Downstream 100 bases:

>100_bases
GCGTTCCGTCGCGCGGTCTGAAAAGAATGCCGACCTGTACGGGTTGGCATTTTTTTCATCCAAAATTTGTTTTCCGATAA
TAATAAACTTGAATGTCATC

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MSRKYFGTDGVRGEVGKFPITPEFVMKLGYAAGRVLVNHDQDSRPTVLIGKDTRISGYMLEAALQAGFTAAGVNVLLTGP
LPTPGIAYLTRALRLEAGVVISASHNPFQDNGIKFFAEGGNKLDDALELEIEAMLDQPMATNPSLELGRARRIDGAAERY
IEFCKSTFPNELSLKGLKLVVDCANGATYHIAPKVFHELGAELVEIGCEPNGYNINDKVGATYPKTLQMAVLEHQADFGI
ALDGDGDRLIMVDAAGRVYDGDQLIYVIAKARAARGELKGGVVGTVMTNMAMELALQKQGVPFGRAKVGDRYVLEMLHAD
GWQVGGEASGHILCLDKHSTGDGIISSLQVLASLKQLGLSLAEICADWRPFPQTLINVRHNGCDWKAASAAPLAEAEAAL
QGRGRVVLRPSGTEPVVRVMVEADDKALADTWAKAIAAAIEKVSA

Sequences:

>Translated_445_residues
MSRKYFGTDGVRGEVGKFPITPEFVMKLGYAAGRVLVNHDQDSRPTVLIGKDTRISGYMLEAALQAGFTAAGVNVLLTGP
LPTPGIAYLTRALRLEAGVVISASHNPFQDNGIKFFAEGGNKLDDALELEIEAMLDQPMATNPSLELGRARRIDGAAERY
IEFCKSTFPNELSLKGLKLVVDCANGATYHIAPKVFHELGAELVEIGCEPNGYNINDKVGATYPKTLQMAVLEHQADFGI
ALDGDGDRLIMVDAAGRVYDGDQLIYVIAKARAARGELKGGVVGTVMTNMAMELALQKQGVPFGRAKVGDRYVLEMLHAD
GWQVGGEASGHILCLDKHSTGDGIISSLQVLASLKQLGLSLAEICADWRPFPQTLINVRHNGCDWKAASAAPLAEAEAAL
QGRGRVVLRPSGTEPVVRVMVEADDKALADTWAKAIAAAIEKVSA
>Mature_444_residues
SRKYFGTDGVRGEVGKFPITPEFVMKLGYAAGRVLVNHDQDSRPTVLIGKDTRISGYMLEAALQAGFTAAGVNVLLTGPL
PTPGIAYLTRALRLEAGVVISASHNPFQDNGIKFFAEGGNKLDDALELEIEAMLDQPMATNPSLELGRARRIDGAAERYI
EFCKSTFPNELSLKGLKLVVDCANGATYHIAPKVFHELGAELVEIGCEPNGYNINDKVGATYPKTLQMAVLEHQADFGIA
LDGDGDRLIMVDAAGRVYDGDQLIYVIAKARAARGELKGGVVGTVMTNMAMELALQKQGVPFGRAKVGDRYVLEMLHADG
WQVGGEASGHILCLDKHSTGDGIISSLQVLASLKQLGLSLAEICADWRPFPQTLINVRHNGCDWKAASAAPLAEAEAALQ
GRGRVVLRPSGTEPVVRVMVEADDKALADTWAKAIAAAIEKVSA

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=451, Percent_Identity=59.2017738359202, Blast_Score=514, Evalue=1e-147,
Organism=Escherichia coli, GI1788361, Length=441, Percent_Identity=26.984126984127, Blast_Score=108, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_CHRVO (Q7NRI6)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_903465.1
- ProteinModelPortal:   Q7NRI6
- SMR:   Q7NRI6
- GeneID:   2547678
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_3795
- NMPDR:   fig|243365.1.peg.3795
- HOGENOM:   HBG644964
- OMA:   EEAGINS
- PhylomeDB:   Q7NRI6
- ProtClustDB:   PRK10887
- BioCyc:   CVIO243365:CV_3795-MONOMER
- BRENDA:   5.4.2.10
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 47553; Mature: 47422

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKYFGTDGVRGEVGKFPITPEFVMKLGYAAGRVLVNHDQDSRPTVLIGKDTRISGYML
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCEEEEECCCCCCCEEEEECCCCCCHHHH
EAALQAGFTAAGVNVLLTGPLPTPGIAYLTRALRLEAGVVISASHNPFQDNGIKFFAEGG
HHHHHCCCEECCCEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEECCC
NKLDDALELEIEAMLDQPMATNPSLELGRARRIDGAAERYIEFCKSTFPNELSLKGLKLV
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEE
VDCANGATYHIAPKVFHELGAELVEIGCEPNGYNINDKVGATYPKTLQMAVLEHQADFGI
EECCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCE
ALDGDGDRLIMVDAAGRVYDGDQLIYVIAKARAARGELKGGVVGTVMTNMAMELALQKQG
EEECCCCEEEEEECCCCEECCCEEEEEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCC
VPFGRAKVGDRYVLEMLHADGWQVGGEASGHILCLDKHSTGDGIISSLQVLASLKQLGLS
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCHH
LAEICADWRPFPQTLINVRHNGCDWKAASAAPLAEAEAALQGRGRVVLRPSGTEPVVRVM
HHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCEEEEE
VEADDKALADTWAKAIAAAIEKVSA
EECCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRKYFGTDGVRGEVGKFPITPEFVMKLGYAAGRVLVNHDQDSRPTVLIGKDTRISGYML
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCEEEEECCCCCCCEEEEECCCCCCHHHH
EAALQAGFTAAGVNVLLTGPLPTPGIAYLTRALRLEAGVVISASHNPFQDNGIKFFAEGG
HHHHHCCCEECCCEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEECCC
NKLDDALELEIEAMLDQPMATNPSLELGRARRIDGAAERYIEFCKSTFPNELSLKGLKLV
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEE
VDCANGATYHIAPKVFHELGAELVEIGCEPNGYNINDKVGATYPKTLQMAVLEHQADFGI
EECCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCE
ALDGDGDRLIMVDAAGRVYDGDQLIYVIAKARAARGELKGGVVGTVMTNMAMELALQKQG
EEECCCCEEEEEECCCCEECCCEEEEEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCC
VPFGRAKVGDRYVLEMLHADGWQVGGEASGHILCLDKHSTGDGIISSLQVLASLKQLGLS
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCHH
LAEICADWRPFPQTLINVRHNGCDWKAASAAPLAEAEAALQGRGRVVLRPSGTEPVVRVM
HHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCEEEEE
VEADDKALADTWAKAIAAAIEKVSA
EECCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782