Click here to switch to the map view.

The map label for this gene is btuE [C]

Identifier: 34499242

GI number: 34499242

Start: 4083876

End: 4084355

Strand: Reverse

Name: btuE [C]

Synonym: CV_3787

Alternate gene names: 34499242

Gene position: 4084355-4083876 (Counterclockwise)

Preceding gene: 34499244

Following gene: 34499239

Centisome position: 85.97

GC content: 64.58

Gene sequence:

>480_bases
ATGACCACGCTCTACGATTTTAGCGCGCAGCGGGCCGACGGCGCCGAACAGGCGCTCTCGGCCTATGAGGGCAGGGTGGC
CTTGCTGGTGAACACCGCCAGCGAGTGCGGCTATACCCGGCAATACGCGGGACTGCAGGAATTGCAGGACTATTTCGCCG
GCCAGGCTTTCGTCGTGCTCGGTTTTCCCTGCAACCAGTTCGGCGGCCAGGAGCCGGGTGGCGAGGACGAGATCGTCGAT
TTCTGCCGCAGCCGTTTCGGCGTGTCCTTCCCGCTGTTCGCCAAGCTGCAGGTGAACGGAGACGGCGCGCATCCCTTGTG
GCGCTGGTTGACCCAGGCCGATTCAGACCGTCCGCATCCGATCAAGTGGAACTTCACCAAGTTCCTGGTCGATGGCCGCG
GCCGGGTGGTGAAGCGCTACGAGCCGGCGGTGGAGCCGCACGAGCTGGTAGACGACATCAAGGCGCTGCTGGCGAGGTGA

Upstream 100 bases:

>100_bases
CGATTGCTGGCGCGCCCGGGACGGGCTTGCTCTGCAAGAGGATCTGGGTCGCAGGCGGCTGCCATTCCGGGCAGCGGCAT
TATACGGGAGGGAGCTTGCC

Downstream 100 bases:

>100_bases
AAGAAAAACGGCCCGCGCGAGCGGGCCGTGGCTGCAGAGCGGATCGCTTACTTGCGGCGGAAGATCACATCCCACACGCC
ATGGCCCAGCTTGATGCCGC

Product: glutathione peroxidase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MTTLYDFSAQRADGAEQALSAYEGRVALLVNTASECGYTRQYAGLQELQDYFAGQAFVVLGFPCNQFGGQEPGGEDEIVD
FCRSRFGVSFPLFAKLQVNGDGAHPLWRWLTQADSDRPHPIKWNFTKFLVDGRGRVVKRYEPAVEPHELVDDIKALLAR

Sequences:

>Translated_159_residues
MTTLYDFSAQRADGAEQALSAYEGRVALLVNTASECGYTRQYAGLQELQDYFAGQAFVVLGFPCNQFGGQEPGGEDEIVD
FCRSRFGVSFPLFAKLQVNGDGAHPLWRWLTQADSDRPHPIKWNFTKFLVDGRGRVVKRYEPAVEPHELVDDIKALLAR
>Mature_158_residues
TTLYDFSAQRADGAEQALSAYEGRVALLVNTASECGYTRQYAGLQELQDYFAGQAFVVLGFPCNQFGGQEPGGEDEIVDF
CRSRFGVSFPLFAKLQVNGDGAHPLWRWLTQADSDRPHPIKWNFTKFLVDGRGRVVKRYEPAVEPHELVDDIKALLAR

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=157, Percent_Identity=45.2229299363057, Blast_Score=136, Evalue=1e-32,
Organism=Homo sapiens, GI75709200, Length=155, Percent_Identity=43.2258064516129, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI90903240, Length=155, Percent_Identity=43.2258064516129, Blast_Score=128, Evalue=2e-30,
Organism=Homo sapiens, GI192455698, Length=159, Percent_Identity=41.5094339622642, Blast_Score=127, Evalue=3e-30,
Organism=Homo sapiens, GI90903238, Length=130, Percent_Identity=42.3076923076923, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI41406084, Length=187, Percent_Identity=35.8288770053476, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI4557629, Length=179, Percent_Identity=35.7541899441341, Blast_Score=93, Evalue=9e-20,
Organism=Homo sapiens, GI6006001, Length=179, Percent_Identity=35.195530726257, Blast_Score=91, Evalue=3e-19,
Organism=Homo sapiens, GI32967607, Length=184, Percent_Identity=32.6086956521739, Blast_Score=84, Evalue=4e-17,
Organism=Homo sapiens, GI33186887, Length=160, Percent_Identity=34.375, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1788003, Length=170, Percent_Identity=39.4117647058824, Blast_Score=132, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI17506887, Length=161, Percent_Identity=42.2360248447205, Blast_Score=138, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17535473, Length=159, Percent_Identity=42.7672955974843, Blast_Score=135, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI71993584, Length=157, Percent_Identity=41.4012738853503, Blast_Score=132, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI193210707, Length=161, Percent_Identity=39.7515527950311, Blast_Score=113, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17550320, Length=168, Percent_Identity=31.547619047619, Blast_Score=99, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI193209493, Length=168, Percent_Identity=31.547619047619, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71993573, Length=96, Percent_Identity=37.5, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71999642, Length=78, Percent_Identity=39.7435897435897, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6319721, Length=160, Percent_Identity=41.25, Blast_Score=148, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6322228, Length=159, Percent_Identity=40.251572327044, Blast_Score=138, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6322826, Length=161, Percent_Identity=37.2670807453416, Blast_Score=125, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24656777, Length=158, Percent_Identity=39.2405063291139, Blast_Score=123, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24656772, Length=158, Percent_Identity=39.2405063291139, Blast_Score=123, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24656767, Length=158, Percent_Identity=39.2405063291139, Blast_Score=123, Evalue=5e-29,
Organism=Drosophila melanogaster, GI85726443, Length=159, Percent_Identity=42.1383647798742, Blast_Score=119, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 17806; Mature: 17675

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLYDFSAQRADGAEQALSAYEGRVALLVNTASECGYTRQYAGLQELQDYFAGQAFVVL
CCEECCCCCCCCCCHHHHHHHHCCEEEEEEECHHHCCCHHHHCCHHHHHHHHCCCEEEEE
GFPCNQFGGQEPGGEDEIVDFCRSRFGVSFPLFAKLQVNGDGAHPLWRWLTQADSDRPHP
ECCHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCC
IKWNFTKFLVDGRGRVVKRYEPAVEPHELVDDIKALLAR
CEECHHEEEECCCCCEEECCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTLYDFSAQRADGAEQALSAYEGRVALLVNTASECGYTRQYAGLQELQDYFAGQAFVVL
CEECCCCCCCCCCHHHHHHHHCCEEEEEEECHHHCCCHHHHCCHHHHHHHHCCCEEEEE
GFPCNQFGGQEPGGEDEIVDFCRSRFGVSFPLFAKLQVNGDGAHPLWRWLTQADSDRPHP
ECCHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCC
IKWNFTKFLVDGRGRVVKRYEPAVEPHELVDDIKALLAR
CEECHHEEEECCCCCEEECCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]