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The map label for this gene is xerD [H]

Identifier: 34499125

GI number: 34499125

Start: 3972144

End: 3973031

Strand: Reverse

Name: xerD [H]

Synonym: CV_3670

Alternate gene names: 34499125

Gene position: 3973031-3972144 (Counterclockwise)

Preceding gene: 34499126

Following gene: 34499122

Centisome position: 83.62

GC content: 68.92

Gene sequence:

>888_bases
ATGAGCTCGGATAAGGACAGCATCGACGCCTTCCTCGACCAGCTGTGGCTGGAGGACGGCCTGTCGCAGAACACGCTGGC
CGCCTATCGCCGCGACCTGTCCAAGCTGGCGGCCAGGCTGGCGGAGCGCGGCGTTTCGCTGGAGACGGCCACGCTGGCCG
ATCTGGAGCAGGCCTTGCTGGCCGGCGTGGCCAGCGAAAAGCCGGCCACCCGCGCGCGGCTGACGTCGGCGTTGCGCCGC
TATTACCAGCATCTGTCGCGCAACGGCGTCCGCCAGGACGATCCCAGCGCCCGGCTGGCGTCGCCGAAGCAGGGGCTGAG
GCTGCCCAAGTCGATGTCCGAGATGGACGTGGAGGCGCTGCTGGACGCGCCGGACGTGGAGACGCCGCTGGGCCTGCGCG
ACCGCGCGATGCTGGAAGTGCTGTACGCCAGCGGCCTGCGGGTGTCCGAACTGGTGGGCATGACGCTGAACCAGCTGAAC
CTGCTGGACGGCGTGGTGAAGACCATGGGCAAGGGCAGCAAGGAGAGGCTGGTGCCGCTGGGCGAAATCGCCCAGGACTG
GCTGCTGCGCTATCTGAAGGAAGCGCGGCCGCTGCTCTTGGCCGGCCAGCCGTGCGACGCGGTGTTCGTCACCCAGCGCA
AGGCGGGGATGACGCGGCAGATGGCCTGGCATCTGATCACCCAGTACGCTGGCCGGCAGGGCCTGGCCAAGGTCAGCCCG
CACGTGCTGCGCCATGCCTTCGCCACTCATCTGGTCAATCACGGCGCCGACCTGCGCGTGGTGCAGCTGCTGCTGGGCCA
CGCCGACATCTCCACCACCCAGATCTATACCCATGTCGCGCGCGAGCGGCTGAAGCAACTGCACGCGCGCCATCATCCGC
GCGGCTGA

Upstream 100 bases:

>100_bases
ATCGTGCCCTGCCACCGGGTAGTGGCCAGCGCCGGCCTCGGCGGCTTCAACCAGTCCACCGGCGACGAAACGCTGGACAT
CAAGAAATGGCTGCTGCGGC

Downstream 100 bases:

>100_bases
GGCTGGAACGGGACGAAAGTCCAAACAAAAACGCCCGCTTGCGCGGGCGTTCGTTCCGACTGGCTGGGATCAGGCCGGCT
CGGCCGCGGCCAGCGCGTCC

Product: integrase/recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MSSDKDSIDAFLDQLWLEDGLSQNTLAAYRRDLSKLAARLAERGVSLETATLADLEQALLAGVASEKPATRARLTSALRR
YYQHLSRNGVRQDDPSARLASPKQGLRLPKSMSEMDVEALLDAPDVETPLGLRDRAMLEVLYASGLRVSELVGMTLNQLN
LLDGVVKTMGKGSKERLVPLGEIAQDWLLRYLKEARPLLLAGQPCDAVFVTQRKAGMTRQMAWHLITQYAGRQGLAKVSP
HVLRHAFATHLVNHGADLRVVQLLLGHADISTTQIYTHVARERLKQLHARHHPRG

Sequences:

>Translated_295_residues
MSSDKDSIDAFLDQLWLEDGLSQNTLAAYRRDLSKLAARLAERGVSLETATLADLEQALLAGVASEKPATRARLTSALRR
YYQHLSRNGVRQDDPSARLASPKQGLRLPKSMSEMDVEALLDAPDVETPLGLRDRAMLEVLYASGLRVSELVGMTLNQLN
LLDGVVKTMGKGSKERLVPLGEIAQDWLLRYLKEARPLLLAGQPCDAVFVTQRKAGMTRQMAWHLITQYAGRQGLAKVSP
HVLRHAFATHLVNHGADLRVVQLLLGHADISTTQIYTHVARERLKQLHARHHPRG
>Mature_294_residues
SSDKDSIDAFLDQLWLEDGLSQNTLAAYRRDLSKLAARLAERGVSLETATLADLEQALLAGVASEKPATRARLTSALRRY
YQHLSRNGVRQDDPSARLASPKQGLRLPKSMSEMDVEALLDAPDVETPLGLRDRAMLEVLYASGLRVSELVGMTLNQLNL
LDGVVKTMGKGSKERLVPLGEIAQDWLLRYLKEARPLLLAGQPCDAVFVTQRKAGMTRQMAWHLITQYAGRQGLAKVSPH
VLRHAFATHLVNHGADLRVVQLLLGHADISTTQIYTHVARERLKQLHARHHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from xerC binding sites by a short central region, forming

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=299, Percent_Identity=60.2006688963211, Blast_Score=336, Evalue=1e-93,
Organism=Escherichia coli, GI1790244, Length=292, Percent_Identity=38.013698630137, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1790768, Length=170, Percent_Identity=28.8235294117647, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 32724; Mature: 32593

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDKDSIDAFLDQLWLEDGLSQNTLAAYRRDLSKLAARLAERGVSLETATLADLEQALL
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AGVASEKPATRARLTSALRRYYQHLSRNGVRQDDPSARLASPKQGLRLPKSMSEMDVEAL
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHCCCCHHHHHHHHHHH
LDAPDVETPLGLRDRAMLEVLYASGLRVSELVGMTLNQLNLLDGVVKTMGKGSKERLVPL
HCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCH
GEIAQDWLLRYLKEARPLLLAGQPCDAVFVTQRKAGMTRQMAWHLITQYAGRQGLAKVSP
HHHHHHHHHHHHHHCCCEEEECCCCCHHEEEHHHHCHHHHHHHHHHHHHHCCCCHHHHHH
HVLRHAFATHLVNHGADLRVVQLLLGHADISTTQIYTHVARERLKQLHARHHPRG
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SSDKDSIDAFLDQLWLEDGLSQNTLAAYRRDLSKLAARLAERGVSLETATLADLEQALL
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AGVASEKPATRARLTSALRRYYQHLSRNGVRQDDPSARLASPKQGLRLPKSMSEMDVEAL
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHCCCCHHHHHHHHHHH
LDAPDVETPLGLRDRAMLEVLYASGLRVSELVGMTLNQLNLLDGVVKTMGKGSKERLVPL
HCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCH
GEIAQDWLLRYLKEARPLLLAGQPCDAVFVTQRKAGMTRQMAWHLITQYAGRQGLAKVSP
HHHHHHHHHHHHHHCCCEEEECCCCCHHEEEHHHHCHHHHHHHHHHHHHHCCCCHHHHHH
HVLRHAFATHLVNHGADLRVVQLLLGHADISTTQIYTHVARERLKQLHARHHPRG
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]