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The map label for this gene is bsaA [H]

Identifier: 34499010

GI number: 34499010

Start: 3864233

End: 3864709

Strand: Direct

Name: bsaA [H]

Synonym: CV_3555

Alternate gene names: 34499010

Gene position: 3864233-3864709 (Clockwise)

Preceding gene: 34499009

Following gene: 34499017

Centisome position: 81.33

GC content: 66.88

Gene sequence:

>477_bases
ATGAGCATCTACGACTTCTCCTTCCGCCGCCTGGACGGCAGCGAACAGGCGATGGCCGACTACCGCGGCAGCGTGCTGCT
GCTGGTCAACACCGCCAGCCGCTGCGGCTTCACGTCGCAATACGCCGGCCTGGAGGCGCTGCACCGCCGCTTCGGCCCGC
AAGGCCTGGCGATCATCGGCTTCCCCTGCAACCAGTTCGGCGCCCAGGAGCCGGGCGACGCCGGCGAAATCGGCGCCTTC
TGCCAGAAGAACTACGGCGTGGACTTCGCCATGGCCGACAAGGTGGACGTCAACGGCGCGAACGCCCACCCGCTGTGGCA
GTATCTGAAGCGGCAGAAACGCGGCCTGCTCGGGCAGGCGATACGCTGGAACTTCAGCAAATTCCTGGTGGACCGCCAGG
GCCGGGTGGTCGCGCGCTTCGCCCCGTTCACCCGGCCGGAAAAACTGGCCGCCAGGATAGAAGCGCTGCTCAAATGA

Upstream 100 bases:

>100_bases
CGCGGTTCCCCCTTGCCGCTGCGCCCCCTTTTTATGCCCATACGCTTGCCAGCGCCCGCCAACGAAGCCATCATTTTCTT
TTCCCAGCTTCCCGCCATTC

Downstream 100 bases:

>100_bases
AAAGAGCCGGGCATCGCCCGGCTCCATCGCCGCGTCGTCGCGGCGCAGCGGAATGATCCCGCTCACGCGCACGAATCGAT
ATTGCGCCTGGCGCTCACAG

Product: glutathione peroxidase protein

Products: glutathione disulfide; H2O

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MSIYDFSFRRLDGSEQAMADYRGSVLLLVNTASRCGFTSQYAGLEALHRRFGPQGLAIIGFPCNQFGAQEPGDAGEIGAF
CQKNYGVDFAMADKVDVNGANAHPLWQYLKRQKRGLLGQAIRWNFSKFLVDRQGRVVARFAPFTRPEKLAARIEALLK

Sequences:

>Translated_158_residues
MSIYDFSFRRLDGSEQAMADYRGSVLLLVNTASRCGFTSQYAGLEALHRRFGPQGLAIIGFPCNQFGAQEPGDAGEIGAF
CQKNYGVDFAMADKVDVNGANAHPLWQYLKRQKRGLLGQAIRWNFSKFLVDRQGRVVARFAPFTRPEKLAARIEALLK
>Mature_157_residues
SIYDFSFRRLDGSEQAMADYRGSVLLLVNTASRCGFTSQYAGLEALHRRFGPQGLAIIGFPCNQFGAQEPGDAGEIGAFC
QKNYGVDFAMADKVDVNGANAHPLWQYLKRQKRGLLGQAIRWNFSKFLVDRQGRVVARFAPFTRPEKLAARIEALLK

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=148, Percent_Identity=46.6216216216216, Blast_Score=137, Evalue=3e-33,
Organism=Homo sapiens, GI90903240, Length=148, Percent_Identity=46.6216216216216, Blast_Score=136, Evalue=6e-33,
Organism=Homo sapiens, GI15618997, Length=156, Percent_Identity=41.6666666666667, Blast_Score=127, Evalue=3e-30,
Organism=Homo sapiens, GI192455698, Length=158, Percent_Identity=36.7088607594937, Blast_Score=117, Evalue=5e-27,
Organism=Homo sapiens, GI90903238, Length=130, Percent_Identity=46.9230769230769, Blast_Score=117, Evalue=6e-27,
Organism=Homo sapiens, GI4557629, Length=183, Percent_Identity=35.5191256830601, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI6006001, Length=160, Percent_Identity=36.875, Blast_Score=94, Evalue=4e-20,
Organism=Homo sapiens, GI41406084, Length=183, Percent_Identity=34.9726775956284, Blast_Score=92, Evalue=1e-19,
Organism=Homo sapiens, GI32967607, Length=182, Percent_Identity=31.8681318681319, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI33186887, Length=160, Percent_Identity=33.125, Blast_Score=78, Evalue=4e-15,
Organism=Homo sapiens, GI41406082, Length=80, Percent_Identity=48.75, Blast_Score=67, Evalue=9e-12,
Organism=Escherichia coli, GI1788003, Length=166, Percent_Identity=38.5542168674699, Blast_Score=129, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17506887, Length=157, Percent_Identity=40.1273885350318, Blast_Score=142, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI17535473, Length=158, Percent_Identity=41.1392405063291, Blast_Score=142, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI193210707, Length=161, Percent_Identity=43.4782608695652, Blast_Score=139, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI71993584, Length=157, Percent_Identity=41.4012738853503, Blast_Score=134, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17550320, Length=180, Percent_Identity=34.4444444444444, Blast_Score=110, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI193209493, Length=180, Percent_Identity=34.4444444444444, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71999642, Length=76, Percent_Identity=42.1052631578947, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=37.8947368421053, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI193210709, Length=72, Percent_Identity=44.4444444444444, Blast_Score=66, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6322228, Length=138, Percent_Identity=55.7971014492754, Blast_Score=175, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6319721, Length=157, Percent_Identity=50.3184713375796, Blast_Score=174, Evalue=8e-45,
Organism=Saccharomyces cerevisiae, GI6322826, Length=155, Percent_Identity=44.5161290322581, Blast_Score=139, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24656777, Length=158, Percent_Identity=44.3037974683544, Blast_Score=146, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24656767, Length=158, Percent_Identity=44.3037974683544, Blast_Score=145, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24656772, Length=158, Percent_Identity=44.3037974683544, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI85726443, Length=162, Percent_Identity=41.358024691358, Blast_Score=110, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: 1.11.1.9

Molecular weight: Translated: 17623; Mature: 17492

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIYDFSFRRLDGSEQAMADYRGSVLLLVNTASRCGFTSQYAGLEALHRRFGPQGLAIIG
CCCCCCHHHHCCCCHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEE
FPCNQFGAQEPGDAGEIGAFCQKNYGVDFAMADKVDVNGANAHPLWQYLKRQKRGLLGQA
CCCHHCCCCCCCCCCHHHHHHHHCCCCCEEECCCEECCCCCCCHHHHHHHHHHHCHHHHH
IRWNFSKFLVDRQGRVVARFAPFTRPEKLAARIEALLK
HHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SIYDFSFRRLDGSEQAMADYRGSVLLLVNTASRCGFTSQYAGLEALHRRFGPQGLAIIG
CCCCCHHHHCCCCHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEE
FPCNQFGAQEPGDAGEIGAFCQKNYGVDFAMADKVDVNGANAHPLWQYLKRQKRGLLGQA
CCCHHCCCCCCCCCCHHHHHHHHCCCCCEEECCCEECCCCCCCHHHHHHHHHHHCHHHHH
IRWNFSKFLVDRQGRVVARFAPFTRPEKLAARIEALLK
HHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutathione; H2O2

Specific reaction: 2 glutathione + H2O2 = glutathione disulfide + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10086841; 11058132 [H]