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The map label for this gene is kdsC [H]

Identifier: 34498783

GI number: 34498783

Start: 3627737

End: 3628261

Strand: Direct

Name: kdsC [H]

Synonym: CV_3328

Alternate gene names: 34498783

Gene position: 3627737-3628261 (Clockwise)

Preceding gene: 34498782

Following gene: 34498784

Centisome position: 76.36

GC content: 67.24

Gene sequence:

>525_bases
ATGCGTATGATTTCCGAGCAGGCCCGCAAGGTGAAACTGCTGATCATGGATGTGGACGGCGTTCTCACCGACGGCCGCAT
CTACTACAACGCCCAGGGCGAGGAGAGCAAGTCCTTCTACGTGCAGGACGGCCTCGGCCTGCGCCTGCTGCAGGGCGCAG
GCGTGCAGCTGGCCATCATCTCCGGCCGCGCCGACCGCTGCGTCGAGCATCGCGCCCGCGCGCTGAACATCGACCATTAC
TACGGCGGCGTCCACGACAAGCAAGTCGCGCTGGCCGATCTGCTGGACAAGACCGGCCTGTCCGCCGACGAGTGCGCCTT
CATCGGCGACGACCTGATCGACCTTCCCATCCTGACCCGGGTCGGCCTGGCCGTGGCCGTGCCCGAGGCTCCGCCGCAGG
TGCGCCAGCATTGCCATTACGTGACCGGCAACCCCGGCGGCCACGGCGCGGTGCGCGAGCTCGCCGAGCTGATCATGCAG
GCCCAGGGCAGTTTCGAAGGCGTGCTCGCACGGTATCTGGCATGA

Upstream 100 bases:

>100_bases
AAGCTGGCCGGCGTGCTCCACATGCACGACCTGCTGCACGCCGGCGTGTTTTAACACCAGCCGGCCGGTCGCATCGACCG
GCGGCGGCAAGGATCAAGCA

Downstream 100 bases:

>100_bases
TCAAGCTGCTGCGCTCACACCGCCTGTTCCCGGTGCTGCTGATCGGCCTGACCGCGCTGCTGACGGTATGGCTGGACCAG
ATCTCGCGCTGGGACAGCCA

Product: hypothetical protein

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MRMISEQARKVKLLIMDVDGVLTDGRIYYNAQGEESKSFYVQDGLGLRLLQGAGVQLAIISGRADRCVEHRARALNIDHY
YGGVHDKQVALADLLDKTGLSADECAFIGDDLIDLPILTRVGLAVAVPEAPPQVRQHCHYVTGNPGGHGAVRELAELIMQ
AQGSFEGVLARYLA

Sequences:

>Translated_174_residues
MRMISEQARKVKLLIMDVDGVLTDGRIYYNAQGEESKSFYVQDGLGLRLLQGAGVQLAIISGRADRCVEHRARALNIDHY
YGGVHDKQVALADLLDKTGLSADECAFIGDDLIDLPILTRVGLAVAVPEAPPQVRQHCHYVTGNPGGHGAVRELAELIMQ
AQGSFEGVLARYLA
>Mature_174_residues
MRMISEQARKVKLLIMDVDGVLTDGRIYYNAQGEESKSFYVQDGLGLRLLQGAGVQLAIISGRADRCVEHRARALNIDHY
YGGVHDKQVALADLLDKTGLSADECAFIGDDLIDLPILTRVGLAVAVPEAPPQVRQHCHYVTGNPGGHGAVRELAELIMQ
AQGSFEGVLARYLA

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=154, Percent_Identity=33.7662337662338, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI2367202, Length=160, Percent_Identity=45.625, Blast_Score=147, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 18898; Mature: 18898

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMISEQARKVKLLIMDVDGVLTDGRIYYNAQGEESKSFYVQDGLGLRLLQGAGVQLAII
CCCCHHHCCEEEEEEEECCCEEECCEEEECCCCCCCCEEEEECCCCEEEECCCCEEEEEE
SGRADRCVEHRARALNIDHYYGGVHDKQVALADLLDKTGLSADECAFIGDDLIDLPILTR
CCCHHHHHHHHHHEECCHHHCCCCCCHHHHHHHHHHHCCCCCCHHEECCCCHHHHHHHHH
VGLAVAVPEAPPQVRQHCHYVTGNPGGHGAVRELAELIMQAQGSFEGVLARYLA
CCEEEECCCCCHHHHHCCEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCC
>Mature Secondary Structure
MRMISEQARKVKLLIMDVDGVLTDGRIYYNAQGEESKSFYVQDGLGLRLLQGAGVQLAII
CCCCHHHCCEEEEEEEECCCEEECCEEEECCCCCCCCEEEEECCCCEEEECCCCEEEEEE
SGRADRCVEHRARALNIDHYYGGVHDKQVALADLLDKTGLSADECAFIGDDLIDLPILTR
CCCHHHHHHHHHHEECCHHHCCCCCCHHHHHHHHHHHCCCCCCHHEECCCCHHHHHHHHH
VGLAVAVPEAPPQVRQHCHYVTGNPGGHGAVRELAELIMQAQGSFEGVLARYLA
CCEEEECCCCCHHHHHCCEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]