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The map label for this gene is CFA [H]

Identifier: 34498681

GI number: 34498681

Start: 3508200

End: 3509324

Strand: Direct

Name: CFA [H]

Synonym: CV_3226

Alternate gene names: 34498681

Gene position: 3508200-3509324 (Clockwise)

Preceding gene: 34498680

Following gene: 34498682

Centisome position: 73.84

GC content: 68.98

Gene sequence:

>1125_bases
CTGCGCCACGGCAGCCTCAAACTCATCACCCCGGATGGCGAGACCCTGTGGTTCGGCGCTCTCCATGCGGAAACCGACGC
CGAGCTGCAGCTGCGCGACTGGCGCGCCTGCGGCCGCATCCTGGCCGGCGGCGATATCGGCTTTGCCGAGGCCTATCGCG
ACGGCTGGCTGGACAGCCCCGACCTGACGGCGCTGCTGCGGCTGGCGCTGCGCAACGAGGACGCCTTGCAGCTGGGCAGG
CTAGGCCGCTGGGCCGCGCGCTGCTGGCACAAGCTGCGCCACCTGGCGCGCGCCAACAGCCGCCGCGGCAGCCGGCGCAA
CATCCACGCCCATTACGATATCGGCAACGATTTTTACCGGCTGTGGCTGGACCCGAGCTGGACCTATTCCAGCGCCTGGT
TCGCTGGCGACTACAGCCTGCCCCTAGCCGACGCGCAAGCGCGCAAGTACCAGCGCATCTGCGAGCAACTGCGGCTGCGC
CCCGGCATGCGGGTGCTGGAAATCGGCTGCGGCTGGGGCGGCTTCGCCGAGCATGCCGCCCGCCTCGGCGTGGCGGTGCA
TGGCATCACCATCTCGGACGCGCAGCTGGACTTCGCCCGCCGCCGCCTGGCCAACGAACCGCTGGTCAGGCTGGAGCACC
GCGATTACCGCGACCTCTCCGGCCAATACGACGCCATCGTGTCGATCGAGATGTTCGAGGCAGTGGGCGAACGCTACTGG
CGCGGCTATTTCGATACCCTGCGCCGCTGCCTGAAGCCGGGCGGCCAGGCGCTGGCGCAGAGCATCACCATAGAGGAGTC
CCGCTTCGACGCGTACCGCGCCGGCGCCGACTTCATCCAGACCTTCATCTTTCCCGGCGGCATGCTGCCCAGCCGCGAGC
GCTTCCAGAGCGCGGCGCAGCAAAGCGGCCTGGCATGCGGCACGCGGCTGGACTTCGGCGCCGACTACGCGGAAACGCTG
CGCCGCTGGCGCCAGGCCTTCGAGGCCAACCTCGCCGCCATCCGCGGCCAGGGCTTCGACGAGGCCTTCATCCGGCTGTG
GCGGCTGTACCTGTGCTACTGCGAAGCCGGTTTCGACGAAGGCCGCATCGGCGTTTCGCAATTTCTGCTGGAAAGGAATG
CGTGA

Upstream 100 bases:

>100_bases
GCGGCCAGGAGTTGAAGCCATGAGCGCGAGCCAACCCATCGCCTTGTCCCGTCCCGATATTCCCGCCGCCGGGCGGGCGC
TGCAGGCCCTGTTGTCGAAA

Downstream 100 bases:

>100_bases
TGCCGCGCGCCGCCTTCGCCTCCTTGCTGGCCTTGCTGACGGGTTGTGCCGGACCCTCGGTGGCCGATTACGCCGCCAAT
CGCCCGCTGCTGGACCCTGG

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MRHGSLKLITPDGETLWFGALHAETDAELQLRDWRACGRILAGGDIGFAEAYRDGWLDSPDLTALLRLALRNEDALQLGR
LGRWAARCWHKLRHLARANSRRGSRRNIHAHYDIGNDFYRLWLDPSWTYSSAWFAGDYSLPLADAQARKYQRICEQLRLR
PGMRVLEIGCGWGGFAEHAARLGVAVHGITISDAQLDFARRRLANEPLVRLEHRDYRDLSGQYDAIVSIEMFEAVGERYW
RGYFDTLRRCLKPGGQALAQSITIEESRFDAYRAGADFIQTFIFPGGMLPSRERFQSAAQQSGLACGTRLDFGADYAETL
RRWRQAFEANLAAIRGQGFDEAFIRLWRLYLCYCEAGFDEGRIGVSQFLLERNA

Sequences:

>Translated_374_residues
MRHGSLKLITPDGETLWFGALHAETDAELQLRDWRACGRILAGGDIGFAEAYRDGWLDSPDLTALLRLALRNEDALQLGR
LGRWAARCWHKLRHLARANSRRGSRRNIHAHYDIGNDFYRLWLDPSWTYSSAWFAGDYSLPLADAQARKYQRICEQLRLR
PGMRVLEIGCGWGGFAEHAARLGVAVHGITISDAQLDFARRRLANEPLVRLEHRDYRDLSGQYDAIVSIEMFEAVGERYW
RGYFDTLRRCLKPGGQALAQSITIEESRFDAYRAGADFIQTFIFPGGMLPSRERFQSAAQQSGLACGTRLDFGADYAETL
RRWRQAFEANLAAIRGQGFDEAFIRLWRLYLCYCEAGFDEGRIGVSQFLLERNA
>Mature_374_residues
MRHGSLKLITPDGETLWFGALHAETDAELQLRDWRACGRILAGGDIGFAEAYRDGWLDSPDLTALLRLALRNEDALQLGR
LGRWAARCWHKLRHLARANSRRGSRRNIHAHYDIGNDFYRLWLDPSWTYSSAWFAGDYSLPLADAQARKYQRICEQLRLR
PGMRVLEIGCGWGGFAEHAARLGVAVHGITISDAQLDFARRRLANEPLVRLEHRDYRDLSGQYDAIVSIEMFEAVGERYW
RGYFDTLRRCLKPGGQALAQSITIEESRFDAYRAGADFIQTFIFPGGMLPSRERFQSAAQQSGLACGTRLDFGADYAETL
RRWRQAFEANLAAIRGQGFDEAFIRLWRLYLCYCEAGFDEGRIGVSQFLLERNA

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=359, Percent_Identity=33.7047353760446, Blast_Score=171, Evalue=7e-44,
Organism=Caenorhabditis elegans, GI133904226, Length=374, Percent_Identity=34.4919786096257, Blast_Score=201, Evalue=4e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 42682; Mature: 42682

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHGSLKLITPDGETLWFGALHAETDAELQLRDWRACGRILAGGDIGFAEAYRDGWLDSP
CCCCCEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHCCEECCCCCCHHHHHHCCCCCCC
DLTALLRLALRNEDALQLGRLGRWAARCWHKLRHLARANSRRGSRRNIHAHYDIGNDFYR
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEE
LWLDPSWTYSSAWFAGDYSLPLADAQARKYQRICEQLRLRPGMRVLEIGCGWGGFAEHAA
EEECCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHH
RLGVAVHGITISDAQLDFARRRLANEPLVRLEHRDYRDLSGQYDAIVSIEMFEAVGERYW
HHCEEEEEEEECCHHHHHHHHHHCCCCCEEECCCCHHHCCCCCHHEEHHHHHHHHHHHHH
RGYFDTLRRCLKPGGQALAQSITIEESRFDAYRAGADFIQTFIFPGGMLPSRERFQSAAQ
HHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
QSGLACGTRLDFGADYAETLRRWRQAFEANLAAIRGQGFDEAFIRLWRLYLCYCEAGFDE
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
GRIGVSQFLLERNA
CCHHHHHHHHHCCC
>Mature Secondary Structure
MRHGSLKLITPDGETLWFGALHAETDAELQLRDWRACGRILAGGDIGFAEAYRDGWLDSP
CCCCCEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHCCEECCCCCCHHHHHHCCCCCCC
DLTALLRLALRNEDALQLGRLGRWAARCWHKLRHLARANSRRGSRRNIHAHYDIGNDFYR
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEE
LWLDPSWTYSSAWFAGDYSLPLADAQARKYQRICEQLRLRPGMRVLEIGCGWGGFAEHAA
EEECCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHH
RLGVAVHGITISDAQLDFARRRLANEPLVRLEHRDYRDLSGQYDAIVSIEMFEAVGERYW
HHCEEEEEEEECCHHHHHHHHHHCCCCCEEECCCCHHHCCCCCHHEEHHHHHHHHHHHHH
RGYFDTLRRCLKPGGQALAQSITIEESRFDAYRAGADFIQTFIFPGGMLPSRERFQSAAQ
HHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
QSGLACGTRLDFGADYAETLRRWRQAFEANLAAIRGQGFDEAFIRLWRLYLCYCEAGFDE
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
GRIGVSQFLLERNA
CCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]