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The map label for this gene is cphA [H]

Identifier: 34498605

GI number: 34498605

Start: 3433887

End: 3434666

Strand: Reverse

Name: cphA [H]

Synonym: CV_3150

Alternate gene names: 34498605

Gene position: 3434666-3433887 (Counterclockwise)

Preceding gene: 34498607

Following gene: 34498603

Centisome position: 72.29

GC content: 64.62

Gene sequence:

>780_bases
GTGGATATCAAGATGCGCACAGTATTTGGATTCGCCGGCGCGCTGTTGGGCCTGGCGGCCGCCGCCTGCGCGGCGCAGGG
CGGCCTGGCTCTCAAGCACCTGAAGGGCGGCGTGTACGTGGTGGAGGATGGCTATTACGCCAAGGAGAACTCGGTGGTCT
ATGTCGGCGCGGAGCACGTGACCGTGGTGGGCGCCACCTGGACGCCGGATACGGCCCGAGAGCTGGCGCGGCAGATACGC
GCAGTCACCGACAAGCCGATCGCGGAAGTGGTCAATCCCAATTATCACCCCGACCGCGCCGGAGGGAACGCATACTGGAA
GTCCATCGGCGCCCGCATCGTGTCGACCCGGCAGACCGCCGACGAGATGCGCCGGGGGTGGGACGAGGTCGTCGCCTTCA
CCCGCCGCGGCTTTCCCGATTATCCGGCGCTGCCCGTCTCGCTGCCGGACCGCGAGCATCCCGGCGATTTCGAGCTGCAG
GATGGCAGGATCAAGGCTTTCCACCTGGGCGCCGCGCATACCCGCGATGGCATCTTCGTCCATTTTCCGCAGGAGAGGGT
GTTGTACGGCAACTGCATTCTCAAGCAGGAGCTGGGCAACCTGAGTTACGCCGACCTGAACGAATACCCGAAAACGCTGG
AACGGCTCAAGCTCAGCGAGCTCGATTTCGATACGGTCATCGCCGGGCATCTCGACGCCTTGCATGGTCCGGAACTTATC
GACCATTACCAGCGGCTGCTGAAGCGGCAGGCATCGGATGCCGCGGCCGAACGCAGCTGA

Upstream 100 bases:

>100_bases
CGGTTTGGGCAGGCACACCTGATTTTGGAGTTGCGAGCGGATGGCTAGTTCTCTCCATGCGCGAAAAATCAGAACCTTCC
TGCTTTCATTTGAATTAATT

Downstream 100 bases:

>100_bases
GCTCAGGTCTGCCAGGCGGGGCGGCCTTCGACGACCTCGACTATCCAGTCGCCGCGGCGGTCGTAGATCAGGTTGAAAGT
GGTATGGCCTTCGCCGGCGT

Product: beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MDIKMRTVFGFAGALLGLAAAACAAQGGLALKHLKGGVYVVEDGYYAKENSVVYVGAEHVTVVGATWTPDTARELARQIR
AVTDKPIAEVVNPNYHPDRAGGNAYWKSIGARIVSTRQTADEMRRGWDEVVAFTRRGFPDYPALPVSLPDREHPGDFELQ
DGRIKAFHLGAAHTRDGIFVHFPQERVLYGNCILKQELGNLSYADLNEYPKTLERLKLSELDFDTVIAGHLDALHGPELI
DHYQRLLKRQASDAAAERS

Sequences:

>Translated_259_residues
MDIKMRTVFGFAGALLGLAAAACAAQGGLALKHLKGGVYVVEDGYYAKENSVVYVGAEHVTVVGATWTPDTARELARQIR
AVTDKPIAEVVNPNYHPDRAGGNAYWKSIGARIVSTRQTADEMRRGWDEVVAFTRRGFPDYPALPVSLPDREHPGDFELQ
DGRIKAFHLGAAHTRDGIFVHFPQERVLYGNCILKQELGNLSYADLNEYPKTLERLKLSELDFDTVIAGHLDALHGPELI
DHYQRLLKRQASDAAAERS
>Mature_259_residues
MDIKMRTVFGFAGALLGLAAAACAAQGGLALKHLKGGVYVVEDGYYAKENSVVYVGAEHVTVVGATWTPDTARELARQIR
AVTDKPIAEVVNPNYHPDRAGGNAYWKSIGARIVSTRQTADEMRRGWDEVVAFTRRGFPDYPALPVSLPDREHPGDFELQ
DGRIKAFHLGAAHTRDGIFVHFPQERVLYGNCILKQELGNLSYADLNEYPKTLERLKLSELDFDTVIAGHLDALHGPELI
DHYQRLLKRQASDAAAERS

Specific function: Can hydrolyze carbapenem compounds [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001018
- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 28612; Mature: 28612

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00744 BETA_LACTAMASE_B_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKMRTVFGFAGALLGLAAAACAAQGGLALKHLKGGVYVVEDGYYAKENSVVYVGAEHV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCEEECCCCEEEECCCEE
TVVGATWTPDTARELARQIRAVTDKPIAEVVNPNYHPDRAGGNAYWKSIGARIVSTRQTA
EEEEECCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DEMRRGWDEVVAFTRRGFPDYPALPVSLPDREHPGDFELQDGRIKAFHLGAAHTRDGIFV
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCEEEEEEECCCCCCCCEEE
HFPQERVLYGNCILKQELGNLSYADLNEYPKTLERLKLSELDFDTVIAGHLDALHGPELI
ECCCCCEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHH
DHYQRLLKRQASDAAAERS
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDIKMRTVFGFAGALLGLAAAACAAQGGLALKHLKGGVYVVEDGYYAKENSVVYVGAEHV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCEEECCCCEEEECCCEE
TVVGATWTPDTARELARQIRAVTDKPIAEVVNPNYHPDRAGGNAYWKSIGARIVSTRQTA
EEEEECCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DEMRRGWDEVVAFTRRGFPDYPALPVSLPDREHPGDFELQDGRIKAFHLGAAHTRDGIFV
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCEEEEEEECCCCCCCCEEE
HFPQERVLYGNCILKQELGNLSYADLNEYPKTLERLKLSELDFDTVIAGHLDALHGPELI
ECCCCCEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHH
DHYQRLLKRQASDAAAERS
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1856163 [H]