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The map label for this gene is yfhA [H]

Identifier: 34498603

GI number: 34498603

Start: 3430570

End: 3432897

Strand: Reverse

Name: yfhA [H]

Synonym: CV_3148

Alternate gene names: 34498603

Gene position: 3432897-3430570 (Counterclockwise)

Preceding gene: 34498605

Following gene: 34498602

Centisome position: 72.26

GC content: 70.32

Gene sequence:

>2328_bases
ATGGACATTCCCACATACGATGTATCCCCGTTGCATGCACGGGCCGATCCGGCCGAGCGCGCGATAGGCCAGTCCGCGGT
TTTCCAGCGGCTGCTGCAACTGGTGCGGCGGGTGGCGCCCACCGACAAGACGGTATTGATCTGGGGGCCGACCGGCGCCG
GCAAGGAAGTCATTGCCCATGAGCTGCACCGCCACAGCCTGGTGGCCGGGCAGCCTTTCATCGATCTCAACTGCGCGGCG
ATTCCCGAGCACCTGATGGAGGCCGAGCTGTTCGGCCACGCCCGCGGCGCCTTCACCGGCGCGCAGGGCAGCCGGGTCGG
CCTGCTGGCCAGGGTAGGGCGCGGCACGCTGTTTCTGGACGAGATCGGCGAGTTGCCGCTGACGCTGCAGCCCAAATTGC
TGCGGGTGCTGGAGACGCGCAGCTTTCGCCCGCTGGGCTCGGCCGAATCCCAGCATTTCGCCGGACGCGTGGTCGCCGCC
ACGCATCGCGATCTGCAGGCCGCGGTGCGCGACGGACGGTTCCGGGAGGACTTGTATTACCGGCTGTCGGTATTCGTGCT
CAGCCTGCCGGGGCTGGAGCAGCGCCGCGACGACATCCCCGCGCTGATCGAGCATTTCTGCGCGATGCAGCCGCGTCCGC
TGCGCTTCGCCGCCGATGCCGTGACGCGTCTGCAGCACAGCCGCTGGCCGGGCAATGTGCGCCAGCTGCGCAGCCTGGTG
GACCGGCTGGGCGTGCTGGCCGACGGTCCGCTGATCACCGCGGCGGCGCTGGACGAGTTCCTGGAACCGCAGGCCCACGC
ATGGCATGCGGACGCCGCCGAACTGGCCGACGCGCTGCTGGCCTTGCCGGGAGAAGACAAGCTGGCGGCGGCCGAGACGC
TGTTGCTCAACCGGGCATTGCATCTGAGCCGCGGCAACAAGGCCGCGGCCGCGCGCGCGCTGGGCGTCGGCCGCAAGGTG
GTGGAGCGCCGGCTGGGCGCGCGGCAGGACAGGCGGCAGCAGTTGCGCCGCTTGCTGGACGAGGGCGGCCGCTTGATGGA
CGGCGGCGATTTCGCCGCGGCCGAGCGCGAGTTGTCGCGCGGACTGGCGTTGCTGGAAAGCGCCTCATTGCAGGACGAGG
CGAGGGAGGAGCACTTCCACCTGCTGCGCCAGCTCGGCATTTGCCACAGCGCGCGGCACGGCTGGTCCAGCGCGGAGGCG
CTGTCCTGCTACGAAGCCGCGCTGGCCGTGGGCAAGGAGCTGGATTGCGAGCCGGAGATCATGTCCATCCTGTTCGGCAT
CTGGACCAGCCAGCTGATGTCGCTGGAGCTGGACCGGGCTCGCGGCGCGGCGCAGCAGATGCTGCAGCGCGGTCAGGCCA
CCGGGGACGCCAGCGCGCTGGCCGACGCCCATTTCGTGATGGCCAACACCCTGTTCTGGCTTGGCGATCACGCCGAGGTG
CTGGCGTGCCTGGAGCGGGGCGGCCTGCTGGACGGCGGTCCCAGCCGGAGGATGGGAACCCAGGGTTTCGATCTGAGCGG
CCTGGTGCTGACCTTCGAAGGGCTGGCGGCGTTTCAGCTGGGCCAGTTCGCCCAGGCGCGCACGGCGCTGGAGGCGCTGC
GCTCGCGGCAGGGTAGCGAAGACCAGCCTTTCAGCCGCGCCATCGCCCTGCAGGGGGCGGTCTGGCTGGCCTGCCTGTTC
GAAGACGAGGCGCTGGGCAGCCTCGCGACGCAGATGGAGGGGCTGTCGCGGCAACATGGTTTCGCCTTTTACCAGGGCGT
CGCCCAGTTCTTCCTGGGCTGCCATCTGGCGCGGCGCGGCCAGCTCCGGGAAGCGGAGGCCGCGATGGAGGAGGGCTACC
AAGGGCAGATGCTGCGCCATGGCGGCAAGCTGTTCCATTCTTTCTATGCCTGGCAGCGCAGCCGACTGCTGCTTGCCGCC
GGGAGGGCGGAGGAGGCGCTGGCCTTGGCCGACCGCGGGCTGGAACTGGCGATGGCGCACAAGGAGCGAGCCTACCTCGG
CGAATTGCTGATCGCGCGCGCGGACGCGCTGCGTGCCTTGGGCGATGAGTCCGGCGCCGAGCATGGCCTGCGCAGCGCAT
TGACCACGGCGGAAGCGCTGGGCGCGGTGCCGCCCAGGGTGGAGGCCGCGACGCGGCTGGCGGAACTGCTGGCCGAGTCT
GGAAGGGAAGAGCAGGCGCGGGCGTTGCTGGAGTCGGTTTTGCGGGCCTGCGACGGCTCCGCCGAGCCAGCCCATCCCGT
GCTGCAATGGGCGCGCATCCGGCTCGGCAGCCTGCCGGGCGGGCGCGCCGACCACAACGCAACAACAGGTGCAAGCCATG
GCTTTTGA

Upstream 100 bases:

>100_bases
GGCATTCATTTTTTTCATCCTTGTCATTTTAAAAGTCGTTGGCATAATGCCTTGCCATGTTGGGCGCGCCCGCCGGGCGC
GCCGCTTGCGCAAGGTGGCC

Downstream 100 bases:

>100_bases
ACTTTCTCCCAGCGATCTGGAACCCTTGCTGCAAGGGGCGTGCTTTTTCGGCAGCGGCGGCGGCGGGACGATGATTTCCG
CCCGCCATCTGGCGGCGAAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 775; Mature: 775

Protein sequence:

>775_residues
MDIPTYDVSPLHARADPAERAIGQSAVFQRLLQLVRRVAPTDKTVLIWGPTGAGKEVIAHELHRHSLVAGQPFIDLNCAA
IPEHLMEAELFGHARGAFTGAQGSRVGLLARVGRGTLFLDEIGELPLTLQPKLLRVLETRSFRPLGSAESQHFAGRVVAA
THRDLQAAVRDGRFREDLYYRLSVFVLSLPGLEQRRDDIPALIEHFCAMQPRPLRFAADAVTRLQHSRWPGNVRQLRSLV
DRLGVLADGPLITAAALDEFLEPQAHAWHADAAELADALLALPGEDKLAAAETLLLNRALHLSRGNKAAAARALGVGRKV
VERRLGARQDRRQQLRRLLDEGGRLMDGGDFAAAERELSRGLALLESASLQDEAREEHFHLLRQLGICHSARHGWSSAEA
LSCYEAALAVGKELDCEPEIMSILFGIWTSQLMSLELDRARGAAQQMLQRGQATGDASALADAHFVMANTLFWLGDHAEV
LACLERGGLLDGGPSRRMGTQGFDLSGLVLTFEGLAAFQLGQFAQARTALEALRSRQGSEDQPFSRAIALQGAVWLACLF
EDEALGSLATQMEGLSRQHGFAFYQGVAQFFLGCHLARRGQLREAEAAMEEGYQGQMLRHGGKLFHSFYAWQRSRLLLAA
GRAEEALALADRGLELAMAHKERAYLGELLIARADALRALGDESGAEHGLRSALTTAEALGAVPPRVEAATRLAELLAES
GREEQARALLESVLRACDGSAEPAHPVLQWARIRLGSLPGGRADHNATTGASHGF

Sequences:

>Translated_775_residues
MDIPTYDVSPLHARADPAERAIGQSAVFQRLLQLVRRVAPTDKTVLIWGPTGAGKEVIAHELHRHSLVAGQPFIDLNCAA
IPEHLMEAELFGHARGAFTGAQGSRVGLLARVGRGTLFLDEIGELPLTLQPKLLRVLETRSFRPLGSAESQHFAGRVVAA
THRDLQAAVRDGRFREDLYYRLSVFVLSLPGLEQRRDDIPALIEHFCAMQPRPLRFAADAVTRLQHSRWPGNVRQLRSLV
DRLGVLADGPLITAAALDEFLEPQAHAWHADAAELADALLALPGEDKLAAAETLLLNRALHLSRGNKAAAARALGVGRKV
VERRLGARQDRRQQLRRLLDEGGRLMDGGDFAAAERELSRGLALLESASLQDEAREEHFHLLRQLGICHSARHGWSSAEA
LSCYEAALAVGKELDCEPEIMSILFGIWTSQLMSLELDRARGAAQQMLQRGQATGDASALADAHFVMANTLFWLGDHAEV
LACLERGGLLDGGPSRRMGTQGFDLSGLVLTFEGLAAFQLGQFAQARTALEALRSRQGSEDQPFSRAIALQGAVWLACLF
EDEALGSLATQMEGLSRQHGFAFYQGVAQFFLGCHLARRGQLREAEAAMEEGYQGQMLRHGGKLFHSFYAWQRSRLLLAA
GRAEEALALADRGLELAMAHKERAYLGELLIARADALRALGDESGAEHGLRSALTTAEALGAVPPRVEAATRLAELLAES
GREEQARALLESVLRACDGSAEPAHPVLQWARIRLGSLPGGRADHNATTGASHGF
>Mature_775_residues
MDIPTYDVSPLHARADPAERAIGQSAVFQRLLQLVRRVAPTDKTVLIWGPTGAGKEVIAHELHRHSLVAGQPFIDLNCAA
IPEHLMEAELFGHARGAFTGAQGSRVGLLARVGRGTLFLDEIGELPLTLQPKLLRVLETRSFRPLGSAESQHFAGRVVAA
THRDLQAAVRDGRFREDLYYRLSVFVLSLPGLEQRRDDIPALIEHFCAMQPRPLRFAADAVTRLQHSRWPGNVRQLRSLV
DRLGVLADGPLITAAALDEFLEPQAHAWHADAAELADALLALPGEDKLAAAETLLLNRALHLSRGNKAAAARALGVGRKV
VERRLGARQDRRQQLRRLLDEGGRLMDGGDFAAAERELSRGLALLESASLQDEAREEHFHLLRQLGICHSARHGWSSAEA
LSCYEAALAVGKELDCEPEIMSILFGIWTSQLMSLELDRARGAAQQMLQRGQATGDASALADAHFVMANTLFWLGDHAEV
LACLERGGLLDGGPSRRMGTQGFDLSGLVLTFEGLAAFQLGQFAQARTALEALRSRQGSEDQPFSRAIALQGAVWLACLF
EDEALGSLATQMEGLSRQHGFAFYQGVAQFFLGCHLARRGQLREAEAAMEEGYQGQMLRHGGKLFHSFYAWQRSRLLLAA
GRAEEALALADRGLELAMAHKERAYLGELLIARADALRALGDESGAEHGLRSALTTAEALGAVPPRVEAATRLAELLAES
GREEQARALLESVLRACDGSAEPAHPVLQWARIRLGSLPGGRADHNATTGASHGF

Specific function: Probable member of a two-component regulatory system yfhA/yfhK [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788905, Length=306, Percent_Identity=43.1372549019608, Blast_Score=229, Evalue=7e-61,
Organism=Escherichia coli, GI1789233, Length=317, Percent_Identity=39.1167192429022, Blast_Score=223, Evalue=5e-59,
Organism=Escherichia coli, GI1788550, Length=295, Percent_Identity=41.6949152542373, Blast_Score=220, Evalue=3e-58,
Organism=Escherichia coli, GI1790299, Length=331, Percent_Identity=40.785498489426, Blast_Score=216, Evalue=4e-57,
Organism=Escherichia coli, GI87082117, Length=233, Percent_Identity=49.3562231759657, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1790437, Length=315, Percent_Identity=40.6349206349206, Blast_Score=209, Evalue=8e-55,
Organism=Escherichia coli, GI1789087, Length=313, Percent_Identity=40.5750798722045, Blast_Score=205, Evalue=8e-54,
Organism=Escherichia coli, GI87082152, Length=248, Percent_Identity=46.3709677419355, Blast_Score=184, Evalue=3e-47,
Organism=Escherichia coli, GI1786524, Length=325, Percent_Identity=37.5384615384615, Blast_Score=177, Evalue=3e-45,
Organism=Escherichia coli, GI87081872, Length=285, Percent_Identity=38.5964912280702, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI1787583, Length=238, Percent_Identity=40.3361344537815, Blast_Score=158, Evalue=1e-39,
Organism=Escherichia coli, GI1789828, Length=330, Percent_Identity=32.4242424242424, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI87081858, Length=301, Percent_Identity=28.9036544850498, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 84232; Mature: 84232

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIPTYDVSPLHARADPAERAIGQSAVFQRLLQLVRRVAPTDKTVLIWGPTGAGKEVIAH
CCCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHH
ELHRHSLVAGQPFIDLNCAAIPEHLMEAELFGHARGAFTGAQGSRVGLLARVGRGTLFLD
HHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCEEEHH
EIGELPLTLQPKLLRVLETRSFRPLGSAESQHFAGRVVAATHRDLQAAVRDGRFREDLYY
HHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCHHHHHHH
RLSVFVLSLPGLEQRRDDIPALIEHFCAMQPRPLRFAADAVTRLQHSRWPGNVRQLRSLV
HHHHHHHCCCCCHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
DRLGVLADGPLITAAALDEFLEPQAHAWHADAAELADALLALPGEDKLAAAETLLLNRAL
HHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
HLSRGNKAAAARALGVGRKVVERRLGARQDRRQQLRRLLDEGGRLMDGGDFAAAERELSR
HHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHH
GLALLESASLQDEAREEHFHLLRQLGICHSARHGWSSAEALSCYEAALAVGKELDCEPEI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHH
MSILFGIWTSQLMSLELDRARGAAQQMLQRGQATGDASALADAHFVMANTLFWLGDHAEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHH
LACLERGGLLDGGPSRRMGTQGFDLSGLVLTFEGLAAFQLGQFAQARTALEALRSRQGSE
HHHHHHCCCCCCCCCCCCCCCCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DQPFSRAIALQGAVWLACLFEDEALGSLATQMEGLSRQHGFAFYQGVAQFFLGCHLARRG
CCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
QLREAEAAMEEGYQGQMLRHGGKLFHSFYAWQRSRLLLAAGRAEEALALADRGLELAMAH
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHCCCHHHHHH
KERAYLGELLIARADALRALGDESGAEHGLRSALTTAEALGAVPPRVEAATRLAELLAES
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
GREEQARALLESVLRACDGSAEPAHPVLQWARIRLGSLPGGRADHNATTGASHGF
CCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDIPTYDVSPLHARADPAERAIGQSAVFQRLLQLVRRVAPTDKTVLIWGPTGAGKEVIAH
CCCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHH
ELHRHSLVAGQPFIDLNCAAIPEHLMEAELFGHARGAFTGAQGSRVGLLARVGRGTLFLD
HHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCEEEHH
EIGELPLTLQPKLLRVLETRSFRPLGSAESQHFAGRVVAATHRDLQAAVRDGRFREDLYY
HHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCHHHHHHH
RLSVFVLSLPGLEQRRDDIPALIEHFCAMQPRPLRFAADAVTRLQHSRWPGNVRQLRSLV
HHHHHHHCCCCCHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
DRLGVLADGPLITAAALDEFLEPQAHAWHADAAELADALLALPGEDKLAAAETLLLNRAL
HHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
HLSRGNKAAAARALGVGRKVVERRLGARQDRRQQLRRLLDEGGRLMDGGDFAAAERELSR
HHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHH
GLALLESASLQDEAREEHFHLLRQLGICHSARHGWSSAEALSCYEAALAVGKELDCEPEI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHH
MSILFGIWTSQLMSLELDRARGAAQQMLQRGQATGDASALADAHFVMANTLFWLGDHAEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHH
LACLERGGLLDGGPSRRMGTQGFDLSGLVLTFEGLAAFQLGQFAQARTALEALRSRQGSE
HHHHHHCCCCCCCCCCCCCCCCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DQPFSRAIALQGAVWLACLFEDEALGSLATQMEGLSRQHGFAFYQGVAQFFLGCHLARRG
CCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
QLREAEAAMEEGYQGQMLRHGGKLFHSFYAWQRSRLLLAAGRAEEALALADRGLELAMAH
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHCCCHHHHHH
KERAYLGELLIARADALRALGDESGAEHGLRSALTTAEALGAVPPRVEAATRLAELLAES
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
GREEQARALLESVLRACDGSAEPAHPVLQWARIRLGSLPGGRADHNATTGASHGF
CCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]