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The map label for this gene is aroA [H]

Identifier: 34498503

GI number: 34498503

Start: 3325593

End: 3326963

Strand: Direct

Name: aroA [H]

Synonym: CV_3048

Alternate gene names: 34498503

Gene position: 3325593-3326963 (Clockwise)

Preceding gene: 34498492

Following gene: 34498504

Centisome position: 70.0

GC content: 68.42

Gene sequence:

>1371_bases
ATGATTGCCACCATCGCGCCATGGCGGTTACAGTGTCCGCTGCTTAGCATCCATCATCCGAACACAGAACGCGCCCGCCT
CATGGAACAACTGCATCTCAATCCCTGCACCCGCCTCGCCGGCTCCATCAAGCTGCCCGGCTCCAAGAGCATCTCCAACC
GCACGCTGCTGCTGGCCGCGTTGTCAGGCGGCAGCACGCTGGTGCGCGACCTGCTGGACTCCGACGACATCCGCCACATG
CTGAGCGCGCTGAAGCTGCTGGGCGTGAAGATCGAGCAACAAGGAGACAGCCGGGACTTCCGCGTCCAGGGCTGCGGCGG
CGTCTTCCCGGTGAAGAACGCCGAATTGTTTCTCGGCAACGCCGGCACCGCCTTCCGGCCGCTGACCGCGGCGCTGGCGC
TGATGGGCGGCAGTTACCAACTATCCGGCGTGCCGCGCATGCACGAGCGCCCGATCGGCGACCTGGTGGACGCGCTGAAC
GCCGCCGGCGCCCGCATCGAATACCTGGGCCAGCCCGGCTTCCCGCCGCTCGCCGTTTCCCCGGCGGACGTGCGCTGCGC
CGCCCCCATCCAGGTGAAAGGCAATGTTTCCAGCCAGTTCCTCACCGCCCTCCTGATGGCGTTGCCGCTGACCGGCGGCC
AGGCCGAGATCGAAGTGGTGGGCGAGCTGATCTCCAAACCCTATATCGAAATCACGCTGAACCTGATGGCCCGCTTCGGC
GTGCGCGTCGAACGCGACGGCTGGCAGCGCTTCGTCATTCCCGGCGGCCAGCACTACATCTCGCCGGGCGAAGTCTACGT
CGAAGGCGACGCCTCCAGCGCGTCCTATTTCCTGGCGGCCGGCGCGCTGGCCGGCGGACCGGTGCGGGTGGAGGGCGTCG
GCGAGGCCAGCATCCAGGGCGACGTGCGTTTCGCGGAAGCGCTGGAGCGGATGGGCGCATCGGTGCGCCTCGGCGACAAC
TGGATCGAGGCCCGCGCCGAAGGCAGGCTCAAGGCGATCGATCTGGACTGCAACCACATCCCGGACGCGGCGATGACGCT
GGCGGTGGCCGCGCTGGCCGCCGACGGCACCACCACGCTGCGCAACATCGCCAGCTGGCGGGTGAAGGAAACCGACCGCC
TGTCGGCGATGGCGGCCGAGCTGCGCAAGGTGGGCGCGACGGTGGAAGAAGGGCCGGACTACATCCGCGTCACCCCGCCG
GCCGCGCTGACGCCGAACGCCGAGATCGACACCTACGACGACCACCGGATGGCGATGTGCTTCTCGCTGGTTTCGCTGCT
GGGCGCGCCGGTCGTCATCAACGACCCGGGCTGCGTGGCCAAGACCTTCCCGGGCTACTTCCAGGCGCTGGCCGCGCTGC
AGGCGCAATAA

Upstream 100 bases:

>100_bases
GACCCGGCCGGATCCGCCGCGCGTCGCGGGAAGAACGGGCCGGTCAAACCGGGCATTGTAACCGAAGCGGGCTTCGCCGA
GTGGGCGGAATGCGCGCCGC

Downstream 100 bases:

>100_bases
TCGCAATATATTGATGATTTAATCGATAGACTCCACAATATATGCATCACAAAGGAGTCTAACGATGAGCGATCTGTTCC
GGATGCGCCGCGATTTCATG

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MIATIAPWRLQCPLLSIHHPNTERARLMEQLHLNPCTRLAGSIKLPGSKSISNRTLLLAALSGGSTLVRDLLDSDDIRHM
LSALKLLGVKIEQQGDSRDFRVQGCGGVFPVKNAELFLGNAGTAFRPLTAALALMGGSYQLSGVPRMHERPIGDLVDALN
AAGARIEYLGQPGFPPLAVSPADVRCAAPIQVKGNVSSQFLTALLMALPLTGGQAEIEVVGELISKPYIEITLNLMARFG
VRVERDGWQRFVIPGGQHYISPGEVYVEGDASSASYFLAAGALAGGPVRVEGVGEASIQGDVRFAEALERMGASVRLGDN
WIEARAEGRLKAIDLDCNHIPDAAMTLAVAALAADGTTTLRNIASWRVKETDRLSAMAAELRKVGATVEEGPDYIRVTPP
AALTPNAEIDTYDDHRMAMCFSLVSLLGAPVVINDPGCVAKTFPGYFQALAALQAQ

Sequences:

>Translated_456_residues
MIATIAPWRLQCPLLSIHHPNTERARLMEQLHLNPCTRLAGSIKLPGSKSISNRTLLLAALSGGSTLVRDLLDSDDIRHM
LSALKLLGVKIEQQGDSRDFRVQGCGGVFPVKNAELFLGNAGTAFRPLTAALALMGGSYQLSGVPRMHERPIGDLVDALN
AAGARIEYLGQPGFPPLAVSPADVRCAAPIQVKGNVSSQFLTALLMALPLTGGQAEIEVVGELISKPYIEITLNLMARFG
VRVERDGWQRFVIPGGQHYISPGEVYVEGDASSASYFLAAGALAGGPVRVEGVGEASIQGDVRFAEALERMGASVRLGDN
WIEARAEGRLKAIDLDCNHIPDAAMTLAVAALAADGTTTLRNIASWRVKETDRLSAMAAELRKVGATVEEGPDYIRVTPP
AALTPNAEIDTYDDHRMAMCFSLVSLLGAPVVINDPGCVAKTFPGYFQALAALQAQ
>Mature_456_residues
MIATIAPWRLQCPLLSIHHPNTERARLMEQLHLNPCTRLAGSIKLPGSKSISNRTLLLAALSGGSTLVRDLLDSDDIRHM
LSALKLLGVKIEQQGDSRDFRVQGCGGVFPVKNAELFLGNAGTAFRPLTAALALMGGSYQLSGVPRMHERPIGDLVDALN
AAGARIEYLGQPGFPPLAVSPADVRCAAPIQVKGNVSSQFLTALLMALPLTGGQAEIEVVGELISKPYIEITLNLMARFG
VRVERDGWQRFVIPGGQHYISPGEVYVEGDASSASYFLAAGALAGGPVRVEGVGEASIQGDVRFAEALERMGASVRLGDN
WIEARAEGRLKAIDLDCNHIPDAAMTLAVAALAADGTTTLRNIASWRVKETDRLSAMAAELRKVGATVEEGPDYIRVTPP
AALTPNAEIDTYDDHRMAMCFSLVSLLGAPVVINDPGCVAKTFPGYFQALAALQAQ

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=425, Percent_Identity=60.2352941176471, Blast_Score=476, Evalue=1e-135,
Organism=Saccharomyces cerevisiae, GI6320332, Length=447, Percent_Identity=38.4787472035794, Blast_Score=247, Evalue=4e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 48538; Mature: 48538

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIATIAPWRLQCPLLSIHHPNTERARLMEQLHLNPCTRLAGSIKLPGSKSISNRTLLLAA
CCCCCCCCEEECCEEEEECCCHHHHHHHHHHCCCHHHHCCCCEECCCCCCCCCCEEEEEE
LSGGSTLVRDLLDSDDIRHMLSALKLLGVKIEQQGDSRDFRVQGCGGVFPVKNAELFLGN
ECCCHHHHHHHHCCHHHHHHHHHHHHHCEEEECCCCCCCEEEECCCCCCCCCCCEEEEEC
AGTAFRPLTAALALMGGSYQLSGVPRMHERPIGDLVDALNAAGARIEYLGQPGFPPLAVS
CCCCHHHHHHHHHHHCCCEEECCCCCHHCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCC
PADVRCAAPIQVKGNVSSQFLTALLMALPLTGGQAEIEVVGELISKPYIEITLNLMARFG
CCCCEEECCEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHC
VRVERDGWQRFVIPGGQHYISPGEVYVEGDASSASYFLAAGALAGGPVRVEGVGEASIQG
CEEECCCCEEEEECCCCEECCCCEEEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCC
DVRFAEALERMGASVRLGDNWIEARAEGRLKAIDLDCNHIPDAAMTLAVAALAADGTTTL
CHHHHHHHHHCCCEEEECCHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHH
RNIASWRVKETDRLSAMAAELRKVGATVEEGPDYIRVTPPAALTPNAEIDTYDDHRMAMC
HHHHHCCCCCHHHHHHHHHHHHHHCCCHHCCCCEEEECCCCCCCCCCCCCCCCCHHHHHH
FSLVSLLGAPVVINDPGCVAKTFPGYFQALAALQAQ
HHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MIATIAPWRLQCPLLSIHHPNTERARLMEQLHLNPCTRLAGSIKLPGSKSISNRTLLLAA
CCCCCCCCEEECCEEEEECCCHHHHHHHHHHCCCHHHHCCCCEECCCCCCCCCCEEEEEE
LSGGSTLVRDLLDSDDIRHMLSALKLLGVKIEQQGDSRDFRVQGCGGVFPVKNAELFLGN
ECCCHHHHHHHHCCHHHHHHHHHHHHHCEEEECCCCCCCEEEECCCCCCCCCCCEEEEEC
AGTAFRPLTAALALMGGSYQLSGVPRMHERPIGDLVDALNAAGARIEYLGQPGFPPLAVS
CCCCHHHHHHHHHHHCCCEEECCCCCHHCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCC
PADVRCAAPIQVKGNVSSQFLTALLMALPLTGGQAEIEVVGELISKPYIEITLNLMARFG
CCCCEEECCEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHC
VRVERDGWQRFVIPGGQHYISPGEVYVEGDASSASYFLAAGALAGGPVRVEGVGEASIQG
CEEECCCCEEEEECCCCEECCCCEEEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCC
DVRFAEALERMGASVRLGDNWIEARAEGRLKAIDLDCNHIPDAAMTLAVAALAADGTTTL
CHHHHHHHHHCCCEEEECCHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHH
RNIASWRVKETDRLSAMAAELRKVGATVEEGPDYIRVTPPAALTPNAEIDTYDDHRMAMC
HHHHHCCCCCHHHHHHHHHHHHHHCCCHHCCCCEEEECCCCCCCCCCCCCCCCCHHHHHH
FSLVSLLGAPVVINDPGCVAKTFPGYFQALAALQAQ
HHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA