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The map label for this gene is 34498401

Identifier: 34498401

GI number: 34498401

Start: 3225472

End: 3226080

Strand: Direct

Name: 34498401

Synonym: CV_2946

Alternate gene names: NA

Gene position: 3225472-3226080 (Clockwise)

Preceding gene: 34498400

Following gene: 34498402

Centisome position: 67.89

GC content: 69.95

Gene sequence:

>609_bases
ATGCTGGCGCGGCTGCGGCGGCGCTGGCTGCTGGCGAGGCTGCGCGACCCGGCATGGGCCGGCCTGCTGGACGAGCACCC
CGGCGAAGTGGTGAGCCTGGATTGCGAAACCACCAGCCTGAACGTCAGCGAAGCCGAGCTGCTGTCGGTAGGCGCGGTGA
AGCTGCGCGGCGACCGCATCCTGCACAGCGAAGCGCTGTACCTGCTGGTCAAGCCGGACAGCGTCCCCAGCGCCGGCAAC
ATCGCCGTGCACGGGCTGCGGCGCCGGGACCTGGCCGAGGGTCTGCCAGCCCGAGAGGCGGTCTCGCGGCTGCTGGCCTT
CATCGGCGGCCGCCCGCTGCTGGGCTACTACCTGGAATACGACGTCGCCGTGCTGAACAAGTATGTGAAGCCCTGGCTAG
GGATAGGCCTGCCGCAACGGCAGATCGAGCTCTCCGCCCGTTACTACGACTACCGCTTCCGCCAGCGCCCCGACTCCCAC
ATCGACCTCAGCCTGGACGCGCTGCACCGGGAACTGGGCGTGCCCGCGCTGCCGCGCCATGACGCGCTCAACGATGCGCT
GAGCGCGGCGATGTTGTACCAGGCGCTGCGCCGCCGCGGCTTCGGATAA

Upstream 100 bases:

>100_bases
CGCTGTCCACGCTGGAGCGCGATCTGCTCAAGGACGCGCTGGCGGTGGCAAAGCGCTTCAAGACCCAGTTGCGCCATCAT
TACCGGCTGGGGAGCTTCTG

Downstream 100 bases:

>100_bases
GGCCGCAACATCTGTAAACATCTTTCCCTTCAGGCTGCGCCGCCCTGGCATGCCGCTTGCTGAACCCGATGCCGGCAAGC
CATTGTTTCTGATAAAAAAA

Product: DNA polymerase III subunit epsilon

Products: diphosphate; DNAn+1

Alternate protein names: DNA Polymerase III Epsilon Subunit; Exonuclease RNAse T And DNA Polymerase III; Exonuclease; Exonuclease RNAase T And DNA Polymerase III; Exonuclease Superfamily; DNA Polymerase III Epsilon Chain

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MLARLRRRWLLARLRDPAWAGLLDEHPGEVVSLDCETTSLNVSEAELLSVGAVKLRGDRILHSEALYLLVKPDSVPSAGN
IAVHGLRRRDLAEGLPAREAVSRLLAFIGGRPLLGYYLEYDVAVLNKYVKPWLGIGLPQRQIELSARYYDYRFRQRPDSH
IDLSLDALHRELGVPALPRHDALNDALSAAMLYQALRRRGFG

Sequences:

>Translated_202_residues
MLARLRRRWLLARLRDPAWAGLLDEHPGEVVSLDCETTSLNVSEAELLSVGAVKLRGDRILHSEALYLLVKPDSVPSAGN
IAVHGLRRRDLAEGLPAREAVSRLLAFIGGRPLLGYYLEYDVAVLNKYVKPWLGIGLPQRQIELSARYYDYRFRQRPDSH
IDLSLDALHRELGVPALPRHDALNDALSAAMLYQALRRRGFG
>Mature_202_residues
MLARLRRRWLLARLRDPAWAGLLDEHPGEVVSLDCETTSLNVSEAELLSVGAVKLRGDRILHSEALYLLVKPDSVPSAGN
IAVHGLRRRDLAEGLPAREAVSRLLAFIGGRPLLGYYLEYDVAVLNKYVKPWLGIGLPQRQIELSARYYDYRFRQRPDSH
IDLSLDALHRELGVPALPRHDALNDALSAAMLYQALRRRGFG

Specific function: Unknown

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.7

Molecular weight: Translated: 22712; Mature: 22712

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLARLRRRWLLARLRDPAWAGLLDEHPGEVVSLDCETTSLNVSEAELLSVGAVKLRGDRI
CHHHHHHHHHHHHHCCCHHCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHCCEEECCCEE
LHSEALYLLVKPDSVPSAGNIAVHGLRRRDLAEGLPAREAVSRLLAFIGGRPLLGYYLEY
EECCEEEEEECCCCCCCCCCEEEECHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHH
DVAVLNKYVKPWLGIGLPQRQIELSARYYDYRFRQRPDSHIDLSLDALHRELGVPALPRH
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCCCCCCC
DALNDALSAAMLYQALRRRGFG
HHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLARLRRRWLLARLRDPAWAGLLDEHPGEVVSLDCETTSLNVSEAELLSVGAVKLRGDRI
CHHHHHHHHHHHHHCCCHHCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHCCEEECCCEE
LHSEALYLLVKPDSVPSAGNIAVHGLRRRDLAEGLPAREAVSRLLAFIGGRPLLGYYLEY
EECCEEEEEECCCCCCCCCCEEEECHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHH
DVAVLNKYVKPWLGIGLPQRQIELSARYYDYRFRQRPDSHIDLSLDALHRELGVPALPRH
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCCCCCCC
DALNDALSAAMLYQALRRRGFG
HHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA