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The map label for this gene is yegD [H]

Identifier: 34497850

GI number: 34497850

Start: 2577746

End: 2579011

Strand: Reverse

Name: yegD [H]

Synonym: CV_2395

Alternate gene names: 34497850

Gene position: 2579011-2577746 (Counterclockwise)

Preceding gene: 34497851

Following gene: 34497841

Centisome position: 54.28

GC content: 66.51

Gene sequence:

>1266_bases
GTGACTGATCAAACTGCCGCCCGCGCCTGCGGCATAGACTTCGGCACCTCCAACTCCACCGTGGGCTGGCTGCGGCCCGG
CCATGACACCCTGTTGCAGCTGGAAGACGGCAAGATCACGCTGCCCTCGGTGGTGTTCTTCAACTACGAGGAAGACCACT
CCCGCTTCGGCCGCGCCGCGCTGGCCGAATACATAGACGGCTTCGAGGGCCGGCTGATGCGCTCGCTGAAGAGCCTGCTG
GGCTCCAGCCTGATCGACAGCCAGACCGAGGTCCAGGGCAAGGCGCTGCCGTTCCGCCACCTGCTGAAGCTGTTCATCCA
GGAATTGAAGCTGCGCGCCGAAGGCGCCGCCGGCCGCGAATTCGAGCAAGTGGTGCTGGGACGCCCGGTCTACTTCGTCG
ACGACAACCCACAGGCCGACAAGCTGGCCCAGGACACGCTGGCCGACATCGCCCGCCAGGTAGGCTTCAAGGAGATTTCC
TTCCAGCTGGAGCCGATCGCCGCGGCGTTCGACTACGAATCCAACATCCAGAAGGAAGAGCTGGTGCTGATCGTCGACAT
CGGCGGCGGCACCTCGGACTTCACGCTGATCCGCCTGTCGCCGGAGCGCCGCAGCCATGCCGAGCGCCGCGACGACATCC
TGGCCACCGGCGGCGTGCACATCGGCGGCACCGATTTCGACCGCCAGCTGAGCCTGCACGGCGTGATGCCCTTGTTCGGC
TTCAAGACCCGGCTGCGCAACAACGCCGAGATGCCGTCCAGCCAGTACTTCAACTTGGCCACCTGGCACACCATCAACTT
CGCCTACACCCGCAAGGCCTGGATGGACCTGCAGGACGTGCACCGCGACGCCGCCGAGCCGGAAAAGCTGGACCGCCTGT
TCAAGCTGATCCAGGAGCGCGCCGGGCACTGGCTGGCGATGGAAGTGGAAGCCGCCAAGATCGCGCTGTCCGACCGGGAC
AGCCACCGCCTGGCGCTGGACGCCATCGAGCGCGGTCTGCACTGCGACCTGAGCCGCGCCGATTTCGAGACCAGCATCAG
CGCGCTGCTGGACCGCGTCGGCGGCACCGTCGGCAAGCTGCTGGCCGATTCCGGCCTCAAGGCCCAGGATGTCGACACCG
TGTTTTTCACCGGCGGCTCCAGCGGCGTGCCGGCGCTGCGCGACGGCATCCGAGCCTTGCTGCCCAATGCCCGCCACGTG
GAAGGCAATCTGTTCGGCAGCATCGGCAGCGGCCTGGCCATCGAGGCGAAAAAGCGCTACGGCTGA

Upstream 100 bases:

>100_bases
GCCTGCACAAGCTGAAGCGCGATTCCTGAGCGTTTCGCCCTTCCCTTTCCGCGCCATTCCGCGTACCATCGCGCCTCTTT
TATTTTCAAGGAGATGCTAA

Downstream 100 bases:

>100_bases
GCCTGCCAGGCTTGCAATGAAAAACGCCGCGAATCATCGCGGCGTTTTTTTATGGAGACAGCCGTTCAGAAATCCCGCTG
CGGCACCAGCACCGTGCGGT

Product: heat-shock protein Hsp 70

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MTDQTAARACGIDFGTSNSTVGWLRPGHDTLLQLEDGKITLPSVVFFNYEEDHSRFGRAALAEYIDGFEGRLMRSLKSLL
GSSLIDSQTEVQGKALPFRHLLKLFIQELKLRAEGAAGREFEQVVLGRPVYFVDDNPQADKLAQDTLADIARQVGFKEIS
FQLEPIAAAFDYESNIQKEELVLIVDIGGGTSDFTLIRLSPERRSHAERRDDILATGGVHIGGTDFDRQLSLHGVMPLFG
FKTRLRNNAEMPSSQYFNLATWHTINFAYTRKAWMDLQDVHRDAAEPEKLDRLFKLIQERAGHWLAMEVEAAKIALSDRD
SHRLALDAIERGLHCDLSRADFETSISALLDRVGGTVGKLLADSGLKAQDVDTVFFTGGSSGVPALRDGIRALLPNARHV
EGNLFGSIGSGLAIEAKKRYG

Sequences:

>Translated_421_residues
MTDQTAARACGIDFGTSNSTVGWLRPGHDTLLQLEDGKITLPSVVFFNYEEDHSRFGRAALAEYIDGFEGRLMRSLKSLL
GSSLIDSQTEVQGKALPFRHLLKLFIQELKLRAEGAAGREFEQVVLGRPVYFVDDNPQADKLAQDTLADIARQVGFKEIS
FQLEPIAAAFDYESNIQKEELVLIVDIGGGTSDFTLIRLSPERRSHAERRDDILATGGVHIGGTDFDRQLSLHGVMPLFG
FKTRLRNNAEMPSSQYFNLATWHTINFAYTRKAWMDLQDVHRDAAEPEKLDRLFKLIQERAGHWLAMEVEAAKIALSDRD
SHRLALDAIERGLHCDLSRADFETSISALLDRVGGTVGKLLADSGLKAQDVDTVFFTGGSSGVPALRDGIRALLPNARHV
EGNLFGSIGSGLAIEAKKRYG
>Mature_420_residues
TDQTAARACGIDFGTSNSTVGWLRPGHDTLLQLEDGKITLPSVVFFNYEEDHSRFGRAALAEYIDGFEGRLMRSLKSLLG
SSLIDSQTEVQGKALPFRHLLKLFIQELKLRAEGAAGREFEQVVLGRPVYFVDDNPQADKLAQDTLADIARQVGFKEISF
QLEPIAAAFDYESNIQKEELVLIVDIGGGTSDFTLIRLSPERRSHAERRDDILATGGVHIGGTDFDRQLSLHGVMPLFGF
KTRLRNNAEMPSSQYFNLATWHTINFAYTRKAWMDLQDVHRDAAEPEKLDRLFKLIQERAGHWLAMEVEAAKIALSDRDS
HRLALDAIERGLHCDLSRADFETSISALLDRVGGTVGKLLADSGLKAQDVDTVFFTGGSSGVPALRDGIRALLPNARHVE
GNLFGSIGSGLAIEAKKRYG

Specific function: Unknown

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

Organism=Homo sapiens, GI16507237, Length=438, Percent_Identity=25.1141552511416, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI34419635, Length=414, Percent_Identity=25.3623188405797, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI24234688, Length=431, Percent_Identity=23.8979118329466, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI48928056, Length=456, Percent_Identity=23.2456140350877, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI124256496, Length=412, Percent_Identity=24.0291262135922, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI24234686, Length=410, Percent_Identity=23.4146341463415, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI5729877, Length=410, Percent_Identity=22.9268292682927, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI13676857, Length=412, Percent_Identity=23.5436893203883, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87082035, Length=447, Percent_Identity=30.6487695749441, Blast_Score=191, Evalue=8e-50,
Organism=Escherichia coli, GI1788875, Length=402, Percent_Identity=28.8557213930348, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786196, Length=412, Percent_Identity=22.3300970873786, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786870, Length=384, Percent_Identity=23.4375, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17534015, Length=416, Percent_Identity=26.2019230769231, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17534013, Length=416, Percent_Identity=26.2019230769231, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17568549, Length=410, Percent_Identity=25.609756097561, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17507981, Length=412, Percent_Identity=24.2718446601942, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17534771, Length=436, Percent_Identity=24.7706422018349, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322426, Length=436, Percent_Identity=25.9174311926606, Blast_Score=93, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6322505, Length=410, Percent_Identity=23.9024390243902, Blast_Score=90, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6319396, Length=414, Percent_Identity=24.8792270531401, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320950, Length=417, Percent_Identity=24.9400479616307, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323401, Length=452, Percent_Identity=21.2389380530973, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320805, Length=433, Percent_Identity=23.094688221709, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319314, Length=415, Percent_Identity=24.0963855421687, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319972, Length=406, Percent_Identity=24.6305418719212, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323004, Length=411, Percent_Identity=23.8442822384428, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324120, Length=406, Percent_Identity=24.384236453202, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17738165, Length=414, Percent_Identity=25.3623188405797, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24647034, Length=450, Percent_Identity=23.1111111111111, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24647038, Length=450, Percent_Identity=23.1111111111111, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24647036, Length=450, Percent_Identity=23.1111111111111, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI17737967, Length=450, Percent_Identity=23.1111111111111, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI28571721, Length=450, Percent_Identity=23.1111111111111, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI28571719, Length=450, Percent_Identity=23.1111111111111, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24641406, Length=437, Percent_Identity=23.3409610983982, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641408, Length=437, Percent_Identity=23.3409610983982, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641402, Length=437, Percent_Identity=23.3409610983982, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641404, Length=437, Percent_Identity=23.3409610983982, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17737941, Length=410, Percent_Identity=24.8780487804878, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17647515, Length=408, Percent_Identity=23.5294117647059, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 46545; Mature: 46414

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00329 HSP70_2 ; PS01036 HSP70_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQTAARACGIDFGTSNSTVGWLRPGHDTLLQLEDGKITLPSVVFFNYEEDHSRFGRAA
CCCCHHHHHCCCCCCCCCCEEEEECCCCCCEEEECCCCEEECEEEEEECCHHHHHHHHHH
LAEYIDGFEGRLMRSLKSLLGSSLIDSQTEVQGKALPFRHLLKLFIQELKLRAEGAAGRE
HHHHHCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCH
FEQVVLGRPVYFVDDNPQADKLAQDTLADIARQVGFKEISFQLEPIAAAFDYESNIQKEE
HHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCCHHEEEEECCHHEEECCCCCCCCCE
LVLIVDIGGGTSDFTLIRLSPERRSHAERRDDILATGGVHIGGTDFDRQLSLHGVMPLFG
EEEEEECCCCCCCEEEEEECCHHHHHHHHHCCEEEECCEEECCCCCCCEEEHHCCHHHHH
FKTRLRNNAEMPSSQYFNLATWHTINFAYTRKAWMDLQDVHRDAAEPEKLDRLFKLIQER
HHHHHCCCCCCCCCCCEEEEEEEEEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AGHWLAMEVEAAKIALSDRDSHRLALDAIERGLHCDLSRADFETSISALLDRVGGTVGKL
CCCEEEEEEEEEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHH
LADSGLKAQDVDTVFFTGGSSGVPALRDGIRALLPNARHVEGNLFGSIGSGLAIEAKKRY
HHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEECCCEEECCCCCEEEEECCCC
G
C
>Mature Secondary Structure 
TDQTAARACGIDFGTSNSTVGWLRPGHDTLLQLEDGKITLPSVVFFNYEEDHSRFGRAA
CCCHHHHHCCCCCCCCCCEEEEECCCCCCEEEECCCCEEECEEEEEECCHHHHHHHHHH
LAEYIDGFEGRLMRSLKSLLGSSLIDSQTEVQGKALPFRHLLKLFIQELKLRAEGAAGRE
HHHHHCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCH
FEQVVLGRPVYFVDDNPQADKLAQDTLADIARQVGFKEISFQLEPIAAAFDYESNIQKEE
HHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCCHHEEEEECCHHEEECCCCCCCCCE
LVLIVDIGGGTSDFTLIRLSPERRSHAERRDDILATGGVHIGGTDFDRQLSLHGVMPLFG
EEEEEECCCCCCCEEEEEECCHHHHHHHHHCCEEEECCEEECCCCCCCEEEHHCCHHHHH
FKTRLRNNAEMPSSQYFNLATWHTINFAYTRKAWMDLQDVHRDAAEPEKLDRLFKLIQER
HHHHHCCCCCCCCCCCEEEEEEEEEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AGHWLAMEVEAAKIALSDRDSHRLALDAIERGLHCDLSRADFETSISALLDRVGGTVGKL
CCCEEEEEEEEEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHH
LADSGLKAQDVDTVFFTGGSSGVPALRDGIRALLPNARHVEGNLFGSIGSGLAIEAKKRY
HHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEECCCEEECCCCCEEEEECCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7940673; 7984428 [H]