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The map label for this gene is yhdH [H]

Identifier: 34497835

GI number: 34497835

Start: 2562254

End: 2563693

Strand: Direct

Name: yhdH [H]

Synonym: CV_2380

Alternate gene names: 34497835

Gene position: 2562254-2563693 (Clockwise)

Preceding gene: 34497834

Following gene: 34497837

Centisome position: 53.93

GC content: 62.36

Gene sequence:

>1440_bases
TTGAGCCCGCCGGTGACTTCCGCGCGGGTTCATCATTATCTAGGGTTCAGAAAAACAATGAGTCAGAACAAATCGAAAAC
GGGTGGAGAGCCCAAGGCGCGGGACGGCTTCACGTCCAGTTTCGGCGTTTTGGCGGCTACGCTGGGGTCGGCGGTCGGCC
TGGGTAATATCTGGAAATTTCCCTACCTGACGGGGACCAACGGCGGAGCCGGCTTCCTGGTGGTCTATGTATTGGCCACG
CTGGTTGTGGGCCTGCCGGTGATGATTTCGGAGATCATGCTGGGCCGCAAGGCCAAGCGCGACGCCGTCACCTCCTTGGT
CAAGCTGGCCCCGGCCGGACAGCCCTGGTGGCTGGTGGGCGCTTTCGGCGTGTTCGCCGCATTCCTGATCATGGCCTTTT
ATTCCGAAGTGGCGGCCTGGGTATTCGCCTACATCTTCAAGGCCATCGGCGGCGACATCCTGTCGCGCGATCCCAAGGTG
ACGTCCGGCGCCTTCACCGCGCTGATTTCCGATCCGGTGCAATCGTTGCTGTGGCAGTGGCTGGTATTGGCGCTGATCGG
CGGCATCCTGCTGCTGGGGGTGTCCAAGGGCATCGAGGCGGTGACCAAGAAGCTGATGCCGCTGCTGTTCGTCCTGCTGG
TGGTGATCGGCGCGCGCAGCCTGATGCTGCCGGGCGCCGGCCAGGGCCTCGCCTTCCTGTTCGCGCCCGACTTCTCCAAG
ATCAGCGCGGCTGTAGTGCTGACCGCGATGGGTCTGGCCTTTTTCAAGCTGTCCATCGGCATGGGCACCATGATCACCTA
CGGCAGCTATTTCCGCGACGACCAGAACATCCCGCTGACCACTTTCCGCGTGATGTGCGCCGACCTGTTCGTGTCGCTGC
TGGCCGGCATCGCCATCTTCCCGGCCGTGTTCGCCTTCGGCTTCCAGCCGGCCGCCGGACCATCTCTGCTGTTCATCACC
ATTCCGGCGGTGTTCGCCAGCATGCCGCTGGGCCACTTCTTCATGGTGGTGTTCTTCGTCCTGACCGCCATCGCGGCCAC
CGGCGCCATGCTGTCCATCCTGGAAGTGCCTGTGTCGGTGCTGAGCGAGCGCTTCGGCATCAGCCGCGTCAAGGCGACCG
TGATCAATCTGTTGTTGCTGGCGTTGGTGGGTTCCGCCTGCGCGCTGTCCAATAGCCTGACCGCGGATTTCAAGATCTTC
GGCATGACGATGTTCGACCTGTTCGACTTTGTCACCTCGAATGTGCTGATGCCGCTGGGCGGCATCTGCCTGTGCCTGTT
CACCGCCTGGGTGTGGGGTTACGACCGCTTCCGCGCCGCGCTGAGCAACGAAGGCGCGCTGGATAACGAGCGCGTGCTGA
AGCCGCTGTTCTTCGTGCTGCGCTTCGTGTCGCCGGTGCTGATACTGTATGTGATGCTGAAGGGCCTGAAGGTCATCTGA

Upstream 100 bases:

>100_bases
TTGGGCTATTGACTAACAACTTAATCAAATAACTGTCAGAAATGCTTTGCATCCATAAGCGATAGGCTGCAAAATTCTGC
CCCTTGGAAACGAAGGACTA

Downstream 100 bases:

>100_bases
TGCAAGAAAAAGGCCGGACGCGCAGTCTGGCCTTTTTTGTTCCCTGGAAATCAGGGAAGGGGCGTGTCCTCGTCGGGCGC
CGCCACCGGCGGCGGGGTAA

Product: sodium-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MSPPVTSARVHHYLGFRKTMSQNKSKTGGEPKARDGFTSSFGVLAATLGSAVGLGNIWKFPYLTGTNGGAGFLVVYVLAT
LVVGLPVMISEIMLGRKAKRDAVTSLVKLAPAGQPWWLVGAFGVFAAFLIMAFYSEVAAWVFAYIFKAIGGDILSRDPKV
TSGAFTALISDPVQSLLWQWLVLALIGGILLLGVSKGIEAVTKKLMPLLFVLLVVIGARSLMLPGAGQGLAFLFAPDFSK
ISAAVVLTAMGLAFFKLSIGMGTMITYGSYFRDDQNIPLTTFRVMCADLFVSLLAGIAIFPAVFAFGFQPAAGPSLLFIT
IPAVFASMPLGHFFMVVFFVLTAIAATGAMLSILEVPVSVLSERFGISRVKATVINLLLLALVGSACALSNSLTADFKIF
GMTMFDLFDFVTSNVLMPLGGICLCLFTAWVWGYDRFRAALSNEGALDNERVLKPLFFVLRFVSPVLILYVMLKGLKVI

Sequences:

>Translated_479_residues
MSPPVTSARVHHYLGFRKTMSQNKSKTGGEPKARDGFTSSFGVLAATLGSAVGLGNIWKFPYLTGTNGGAGFLVVYVLAT
LVVGLPVMISEIMLGRKAKRDAVTSLVKLAPAGQPWWLVGAFGVFAAFLIMAFYSEVAAWVFAYIFKAIGGDILSRDPKV
TSGAFTALISDPVQSLLWQWLVLALIGGILLLGVSKGIEAVTKKLMPLLFVLLVVIGARSLMLPGAGQGLAFLFAPDFSK
ISAAVVLTAMGLAFFKLSIGMGTMITYGSYFRDDQNIPLTTFRVMCADLFVSLLAGIAIFPAVFAFGFQPAAGPSLLFIT
IPAVFASMPLGHFFMVVFFVLTAIAATGAMLSILEVPVSVLSERFGISRVKATVINLLLLALVGSACALSNSLTADFKIF
GMTMFDLFDFVTSNVLMPLGGICLCLFTAWVWGYDRFRAALSNEGALDNERVLKPLFFVLRFVSPVLILYVMLKGLKVI
>Mature_478_residues
SPPVTSARVHHYLGFRKTMSQNKSKTGGEPKARDGFTSSFGVLAATLGSAVGLGNIWKFPYLTGTNGGAGFLVVYVLATL
VVGLPVMISEIMLGRKAKRDAVTSLVKLAPAGQPWWLVGAFGVFAAFLIMAFYSEVAAWVFAYIFKAIGGDILSRDPKVT
SGAFTALISDPVQSLLWQWLVLALIGGILLLGVSKGIEAVTKKLMPLLFVLLVVIGARSLMLPGAGQGLAFLFAPDFSKI
SAAVVLTAMGLAFFKLSIGMGTMITYGSYFRDDQNIPLTTFRVMCADLFVSLLAGIAIFPAVFAFGFQPAAGPSLLFITI
PAVFASMPLGHFFMVVFFVLTAIAATGAMLSILEVPVSVLSERFGISRVKATVINLLLLALVGSACALSNSLTADFKIFG
MTMFDLFDFVTSNVLMPLGGICLCLFTAWVWGYDRFRAALSNEGALDNERVLKPLFFVLRFVSPVLILYVMLKGLKVI

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI188528618, Length=467, Percent_Identity=23.982869379015, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI197276623, Length=484, Percent_Identity=25, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI54607094, Length=484, Percent_Identity=25, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI92859670, Length=428, Percent_Identity=25.4672897196262, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI171184408, Length=481, Percent_Identity=24.5322245322245, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI171184406, Length=481, Percent_Identity=24.5322245322245, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI171184404, Length=481, Percent_Identity=24.5322245322245, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI21361581, Length=475, Percent_Identity=24.4210526315789, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI134304856, Length=461, Percent_Identity=26.6811279826464, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI289191377, Length=507, Percent_Identity=24.8520710059172, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4507043, Length=380, Percent_Identity=24.7368421052632, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI289191351, Length=507, Percent_Identity=24.8520710059172, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4557046, Length=507, Percent_Identity=24.8520710059172, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI7657587, Length=463, Percent_Identity=24.4060475161987, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI194018524, Length=300, Percent_Identity=29.3333333333333, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI58219014, Length=337, Percent_Identity=26.7062314540059, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI51468073, Length=312, Percent_Identity=22.4358974358974, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI4507041, Length=507, Percent_Identity=22.879684418146, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI11181770, Length=302, Percent_Identity=26.4900662251656, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI5032097, Length=465, Percent_Identity=26.6666666666667, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI218563756, Length=465, Percent_Identity=26.8817204301075, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI33354281, Length=316, Percent_Identity=24.3670886075949, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI6005715, Length=443, Percent_Identity=24.3792325056433, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI67782317, Length=514, Percent_Identity=23.1517509727626, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI67782315, Length=531, Percent_Identity=22.7871939736347, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI67782313, Length=514, Percent_Identity=23.1517509727626, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI12408638, Length=286, Percent_Identity=25.5244755244755, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI197276625, Length=135, Percent_Identity=29.6296296296296, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI300360519, Length=347, Percent_Identity=24.207492795389, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI21361693, Length=155, Percent_Identity=24.5161290322581, Blast_Score=65, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17554804, Length=470, Percent_Identity=28.5106382978723, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI25146584, Length=408, Percent_Identity=24.7549019607843, Blast_Score=105, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI71998244, Length=416, Percent_Identity=25, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17569475, Length=434, Percent_Identity=24.4239631336406, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17555248, Length=121, Percent_Identity=33.8842975206612, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17535731, Length=122, Percent_Identity=34.4262295081967, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI133952791, Length=318, Percent_Identity=26.1006289308176, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI212642127, Length=327, Percent_Identity=26.2996941896024, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17542050, Length=147, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI17136952, Length=439, Percent_Identity=23.9179954441913, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24661428, Length=395, Percent_Identity=26.8354430379747, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24652942, Length=468, Percent_Identity=25.6410256410256, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI45551088, Length=468, Percent_Identity=25.6410256410256, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI281364394, Length=482, Percent_Identity=23.2365145228216, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28574704, Length=482, Percent_Identity=23.2365145228216, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17136950, Length=482, Percent_Identity=23.2365145228216, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28574702, Length=482, Percent_Identity=23.2365145228216, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI19921936, Length=393, Percent_Identity=27.4809160305344, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24762620, Length=499, Percent_Identity=25.0501002004008, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI281364136, Length=517, Percent_Identity=24.1779497098646, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI45550877, Length=489, Percent_Identity=22.6993865030675, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI281363702, Length=507, Percent_Identity=24.4575936883629, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24582567, Length=484, Percent_Identity=23.5537190082645, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI45551183, Length=390, Percent_Identity=23.3333333333333, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24639514, Length=501, Percent_Identity=22.5548902195609, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI221329674, Length=501, Percent_Identity=22.5548902195609, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24655079, Length=315, Percent_Identity=25.7142857142857, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI281363700, Length=324, Percent_Identity=28.7037037037037, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24639516, Length=304, Percent_Identity=26.3157894736842, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI281365034, Length=512, Percent_Identity=21.6796875, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24639853, Length=422, Percent_Identity=24.1706161137441, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24654186, Length=313, Percent_Identity=24.9201277955272, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 51312; Mature: 51181

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPPVTSARVHHYLGFRKTMSQNKSKTGGEPKARDGFTSSFGVLAATLGSAVGLGNIWKF
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
PYLTGTNGGAGFLVVYVLATLVVGLPVMISEIMLGRKAKRDAVTSLVKLAPAGQPWWLVG
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHH
AFGVFAAFLIMAFYSEVAAWVFAYIFKAIGGDILSRDPKVTSGAFTALISDPVQSLLWQW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LVLALIGGILLLGVSKGIEAVTKKLMPLLFVLLVVIGARSLMLPGAGQGLAFLFAPDFSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEEEECCCHHH
ISAAVVLTAMGLAFFKLSIGMGTMITYGSYFRDDQNIPLTTFRVMCADLFVSLLAGIAIF
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
PAVFAFGFQPAAGPSLLFITIPAVFASMPLGHFFMVVFFVLTAIAATGAMLSILEVPVSV
HHHHHHCCCCCCCCCEEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSERFGISRVKATVINLLLLALVGSACALSNSLTADFKIFGMTMFDLFDFVTSNVLMPLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GICLCLFTAWVWGYDRFRAALSNEGALDNERVLKPLFFVLRFVSPVLILYVMLKGLKVI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SPPVTSARVHHYLGFRKTMSQNKSKTGGEPKARDGFTSSFGVLAATLGSAVGLGNIWKF
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
PYLTGTNGGAGFLVVYVLATLVVGLPVMISEIMLGRKAKRDAVTSLVKLAPAGQPWWLVG
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHH
AFGVFAAFLIMAFYSEVAAWVFAYIFKAIGGDILSRDPKVTSGAFTALISDPVQSLLWQW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LVLALIGGILLLGVSKGIEAVTKKLMPLLFVLLVVIGARSLMLPGAGQGLAFLFAPDFSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEEEECCCHHH
ISAAVVLTAMGLAFFKLSIGMGTMITYGSYFRDDQNIPLTTFRVMCADLFVSLLAGIAIF
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
PAVFAFGFQPAAGPSLLFITIPAVFASMPLGHFFMVVFFVLTAIAATGAMLSILEVPVSV
HHHHHHCCCCCCCCCEEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSERFGISRVKATVINLLLLALVGSACALSNSLTADFKIFGMTMFDLFDFVTSNVLMPLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GICLCLFTAWVWGYDRFRAALSNEGALDNERVLKPLFFVLRFVSPVLILYVMLKGLKVI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]