| Definition | Chromobacterium violaceum ATCC 12472 chromosome, complete genome. |
|---|---|
| Accession | NC_005085 |
| Length | 4,751,080 |
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The map label for this gene is phaB [H]
Identifier: 34497819
GI number: 34497819
Start: 2549913
End: 2550653
Strand: Reverse
Name: phaB [H]
Synonym: CV_2364
Alternate gene names: 34497819
Gene position: 2550653-2549913 (Counterclockwise)
Preceding gene: 34497820
Following gene: 34497818
Centisome position: 53.69
GC content: 60.32
Gene sequence:
>741_bases ATGACGAAAAGGATTGCGTTAGTTACCGGTGGCATGGGCGGTATCGGCACCGCCATCTGCAAAGCCTTGGCTGAAGCGGG GCATATCGTGGTAACCACGTACAGCAAACCGGGCCGCGAAGCGTCCTGGCATGCCGACATGAAGGGACTGGGTTTCAGCG ACATCCACAGCTACCTGTGCGACGTCACGGACTTCGCCGCCTGCCAGGATGTGGCTGCCCGCATCGCCAAGGACGTCGGC CAGGTCGATATCCTGGTCAACAATGCAGGCATCACCCGCGACGCCAGCTTCAGGAAACAGAGCAAGGACGACTGGGACGC CGTGATCCGCACCAACCTGGACTCGGTATTCAACATGACCAAGCCCGTGCTGGACAATATGCTGGAAACGGGCTTTGGCC GCATCATCAACATTTCGTCCATCAATGGCCAGAAGGGCCAATTCGGCCAAACGAACTACTCCGCGGCCAAGGCTGGCATG CACGGCTTCACCATGGCGCTGGCTCAGGAAGTGGCCAAGAAGGGCGTGACCGTCAACACCATCTCTCCCGGCTACATCGC CACCGAAATGGTGATGGCGGTGCCGGAAGATGTGCGCAACAAGATCATCGCCCAGATCCCGGTCGGCCGCCTGGGCCGCC CGGAGGAGATCGCCGCACTGGTGACCTTCCTCTGCTCCGACAACGCCGGCTTCATCACCGGCAGCAATATCGCCATGAAC GGCGGCCAGCACATGATGTAA
Upstream 100 bases:
>100_bases GCTATTTATTTACTTTTTATGGCTCCCTGCATATTCTGTAATAAAAGGAAGTAAAGATTATCCAAATATAGATTCCAAAC CCGACAGAGGAGCCAGCATC
Downstream 100 bases:
>100_bases TCGCGTCAAGGCTCCGCAATACTGTTCACGCCGCCTCTCCCGGGCGGCGTTTTCTTTTCTGGTGTATGCTGTCCGGCCCG CCACTCATTCGCAAGCAACA
Product: acetoacetyl-CoA reductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 246; Mature: 245
Protein sequence:
>246_residues MTKRIALVTGGMGGIGTAICKALAEAGHIVVTTYSKPGREASWHADMKGLGFSDIHSYLCDVTDFAACQDVAARIAKDVG QVDILVNNAGITRDASFRKQSKDDWDAVIRTNLDSVFNMTKPVLDNMLETGFGRIINISSINGQKGQFGQTNYSAAKAGM HGFTMALAQEVAKKGVTVNTISPGYIATEMVMAVPEDVRNKIIAQIPVGRLGRPEEIAALVTFLCSDNAGFITGSNIAMN GGQHMM
Sequences:
>Translated_246_residues MTKRIALVTGGMGGIGTAICKALAEAGHIVVTTYSKPGREASWHADMKGLGFSDIHSYLCDVTDFAACQDVAARIAKDVG QVDILVNNAGITRDASFRKQSKDDWDAVIRTNLDSVFNMTKPVLDNMLETGFGRIINISSINGQKGQFGQTNYSAAKAGM HGFTMALAQEVAKKGVTVNTISPGYIATEMVMAVPEDVRNKIIAQIPVGRLGRPEEIAALVTFLCSDNAGFITGSNIAMN GGQHMM >Mature_245_residues TKRIALVTGGMGGIGTAICKALAEAGHIVVTTYSKPGREASWHADMKGLGFSDIHSYLCDVTDFAACQDVAARIAKDVGQ VDILVNNAGITRDASFRKQSKDDWDAVIRTNLDSVFNMTKPVLDNMLETGFGRIINISSINGQKGQFGQTNYSAAKAGMH GFTMALAQEVAKKGVTVNTISPGYIATEMVMAVPEDVRNKIIAQIPVGRLGRPEEIAALVTFLCSDNAGFITGSNIAMNG GQHMM
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=263, Percent_Identity=36.5019011406844, Blast_Score=150, Evalue=7e-37, Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=34.0163934426229, Blast_Score=131, Evalue=5e-31, Organism=Homo sapiens, GI4504505, Length=240, Percent_Identity=33.75, Blast_Score=119, Evalue=3e-27, Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=31.0204081632653, Blast_Score=115, Evalue=5e-26, Organism=Homo sapiens, GI19923817, Length=251, Percent_Identity=31.8725099601594, Blast_Score=111, Evalue=7e-25, Organism=Homo sapiens, GI4758504, Length=255, Percent_Identity=32.156862745098, Blast_Score=100, Evalue=8e-22, Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=31.1475409836066, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI66933014, Length=179, Percent_Identity=31.8435754189944, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=28.6885245901639, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=26.6129032258064, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI59889578, Length=195, Percent_Identity=33.8461538461538, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI4503301, Length=198, Percent_Identity=28.7878787878788, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI109715829, Length=238, Percent_Identity=28.9915966386555, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI83715985, Length=255, Percent_Identity=30.1960784313725, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI10190704, Length=246, Percent_Identity=27.2357723577236, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI31542939, Length=203, Percent_Identity=32.0197044334975, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI20149619, Length=191, Percent_Identity=30.3664921465969, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI40807363, Length=191, Percent_Identity=28.2722513089005, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=30.8900523560209, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI4503817, Length=182, Percent_Identity=29.6703296703297, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI7706318, Length=198, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=29.5081967213115, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI210032110, Length=188, Percent_Identity=27.6595744680851, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI157739938, Length=138, Percent_Identity=31.8840579710145, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI25282469, Length=157, Percent_Identity=28.6624203821656, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI7705855, Length=191, Percent_Identity=30.3664921465969, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI226371731, Length=215, Percent_Identity=30.2325581395349, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI142976729, Length=238, Percent_Identity=25.6302521008403, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=46.1538461538462, Blast_Score=207, Evalue=6e-55, Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=35.0393700787402, Blast_Score=140, Evalue=7e-35, Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=32.6530612244898, Blast_Score=122, Evalue=2e-29, Organism=Escherichia coli, GI87082160, Length=243, Percent_Identity=31.6872427983539, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI1790717, Length=238, Percent_Identity=30.2521008403361, Blast_Score=115, Evalue=3e-27, Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=29.718875502008, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=29.4354838709677, Blast_Score=105, Evalue=3e-24, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=31.4285714285714, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=29.9180327868852, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=30.8641975308642, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=27.2373540856031, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=32.7868852459016, Blast_Score=88, Evalue=4e-19, Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=27.6679841897233, Blast_Score=77, Evalue=9e-16, Organism=Escherichia coli, GI1787526, Length=252, Percent_Identity=25.7936507936508, Blast_Score=66, Evalue=2e-12, Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=41.2244897959184, Blast_Score=170, Evalue=7e-43, Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=38.8663967611336, Blast_Score=165, Evalue=2e-41, Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=31.9838056680162, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=30.9433962264151, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17568967, Length=237, Percent_Identity=32.4894514767932, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17560150, Length=255, Percent_Identity=29.8039215686275, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17562990, Length=255, Percent_Identity=30.5882352941176, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17563726, Length=255, Percent_Identity=31.3725490196078, Blast_Score=104, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=29.6577946768061, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI17561402, Length=248, Percent_Identity=33.0645161290323, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=32.4528301886792, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=30.1526717557252, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=30.3149606299213, Blast_Score=98, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=30.2238805970149, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=30.4511278195489, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=30.6818181818182, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI72000259, Length=255, Percent_Identity=29.0196078431373, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=27.843137254902, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=29.0566037735849, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=30, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=29.1187739463602, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI71994604, Length=256, Percent_Identity=28.515625, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=29.9180327868852, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17508651, Length=249, Percent_Identity=27.3092369477912, Blast_Score=87, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17536651, Length=248, Percent_Identity=29.0322580645161, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17536025, Length=249, Percent_Identity=30.5220883534137, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=28.735632183908, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17561272, Length=193, Percent_Identity=30.5699481865285, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17531453, Length=267, Percent_Identity=28.0898876404494, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=28.0769230769231, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI193203115, Length=187, Percent_Identity=29.9465240641711, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI193203117, Length=190, Percent_Identity=29.4736842105263, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=25.3787878787879, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17564282, Length=235, Percent_Identity=27.2340425531915, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17508895, Length=193, Percent_Identity=26.9430051813472, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17558006, Length=204, Percent_Identity=29.4117647058824, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI193207185, Length=149, Percent_Identity=30.8724832214765, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17507613, Length=227, Percent_Identity=25.5506607929515, Blast_Score=64, Evalue=7e-11, Organism=Caenorhabditis elegans, GI32563809, Length=227, Percent_Identity=25.5506607929515, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=243, Percent_Identity=32.0987654320988, Blast_Score=100, Evalue=2e-22, Organism=Saccharomyces cerevisiae, GI6324126, Length=249, Percent_Identity=26.9076305220884, Blast_Score=73, Evalue=4e-14, Organism=Saccharomyces cerevisiae, GI6320089, Length=197, Percent_Identity=26.3959390862944, Blast_Score=70, Evalue=3e-13, Organism=Saccharomyces cerevisiae, GI6323882, Length=198, Percent_Identity=26.2626262626263, Blast_Score=64, Evalue=3e-11, Organism=Drosophila melanogaster, GI24639444, Length=244, Percent_Identity=38.1147540983607, Blast_Score=151, Evalue=4e-37, Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=33.596837944664, Blast_Score=124, Evalue=5e-29, Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=30.9236947791165, Blast_Score=119, Evalue=3e-27, Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=30.9236947791165, Blast_Score=117, Evalue=5e-27, Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=31.8181818181818, Blast_Score=117, Evalue=5e-27, Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=30.1204819277108, Blast_Score=112, Evalue=2e-25, Organism=Drosophila melanogaster, GI24643142, Length=241, Percent_Identity=30.7053941908714, Blast_Score=109, Evalue=2e-24, Organism=Drosophila melanogaster, GI18859837, Length=242, Percent_Identity=34.7107438016529, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI17737361, Length=269, Percent_Identity=30.4832713754647, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24644337, Length=173, Percent_Identity=32.3699421965318, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI21358495, Length=192, Percent_Identity=28.125, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI116007236, Length=217, Percent_Identity=30.8755760368664, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI21355631, Length=170, Percent_Identity=32.3529411764706, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI24648693, Length=199, Percent_Identity=29.1457286432161, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI21355889, Length=199, Percent_Identity=29.1457286432161, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI24584748, Length=189, Percent_Identity=32.8042328042328, Blast_Score=73, Evalue=1e-13, Organism=Drosophila melanogaster, GI161076933, Length=189, Percent_Identity=32.8042328042328, Blast_Score=73, Evalue=1e-13, Organism=Drosophila melanogaster, GI281364892, Length=170, Percent_Identity=31.7647058823529, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24641388, Length=230, Percent_Identity=28.695652173913, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24641232, Length=209, Percent_Identity=27.7511961722488, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24581726, Length=143, Percent_Identity=28.6713286713287, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI28571387, Length=208, Percent_Identity=25.9615384615385, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI116007238, Length=188, Percent_Identity=29.7872340425532, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI116007234, Length=213, Percent_Identity=27.6995305164319, Blast_Score=65, Evalue=6e-11, Organism=Drosophila melanogaster, GI24663911, Length=219, Percent_Identity=27.3972602739726, Blast_Score=64, Evalue=9e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011283 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.36 [H]
Molecular weight: Translated: 26189; Mature: 26058
Theoretical pI: Translated: 7.50; Mature: 7.50
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 4.9 %Met (Translated Protein) 6.5 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 4.5 %Met (Mature Protein) 6.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTKRIALVTGGMGGIGTAICKALAEAGHIVVTTYSKPGREASWHADMKGLGFSDIHSYLC CCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHH DVTDFAACQDVAARIAKDVGQVDILVNNAGITRDASFRKQSKDDWDAVIRTNLDSVFNMT HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHH KPVLDNMLETGFGRIINISSINGQKGQFGQTNYSAAKAGMHGFTMALAQEVAKKGVTVNT HHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCEEEE ISPGYIATEMVMAVPEDVRNKIIAQIPVGRLGRPEEIAALVTFLCSDNAGFITGSNIAMN CCCCHHHHHHHHHCCHHHHHHEEHHCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCEEEC GGQHMM CCCCCC >Mature Secondary Structure TKRIALVTGGMGGIGTAICKALAEAGHIVVTTYSKPGREASWHADMKGLGFSDIHSYLC CCEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHH DVTDFAACQDVAARIAKDVGQVDILVNNAGITRDASFRKQSKDDWDAVIRTNLDSVFNMT HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHH KPVLDNMLETGFGRIINISSINGQKGQFGQTNYSAAKAGMHGFTMALAQEVAKKGVTVNT HHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCEEEE ISPGYIATEMVMAVPEDVRNKIIAQIPVGRLGRPEEIAALVTFLCSDNAGFITGSNIAMN CCCCHHHHHHHHHCCHHHHHHEEHHCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCEEEC GGQHMM CCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2670935 [H]