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The map label for this gene is cysN

Identifier: 34497762

GI number: 34497762

Start: 2497319

End: 2498752

Strand: Direct

Name: cysN

Synonym: CV_2307

Alternate gene names: 34497762

Gene position: 2497319-2498752 (Clockwise)

Preceding gene: 34497761

Following gene: 34497764

Centisome position: 52.56

GC content: 65.34

Gene sequence:

>1434_bases
ATGTCGCACCAATCCGAACTGATCGCCGGGGATATCCTGGAATACCTGAGCCAGCATGAGAACAAGGACATGCTGCGCTT
CATCACCTGCGGCAGCGTGGACGACGGCAAGTCCACGCTGATCGGCCGGCTGCTGCACGACTCCAAGCTGATTTTCGAGG
ACCAGCTGGCGGCGATCGAGCGCGACTCGAAAAAATACAACACCACCGACCAGGACATCGACTTGGCGCTGCTGGTGGAC
GGCCTGCAGGCCGAGCGCGAGCAGGGCATTACCATAGACGTCGCCTACCGCTACTTCAGCACCGACAAGCGCAAGTTCAT
CATCGCCGATTGCCCAGGCCACGAGCAGTACACCCGCAACATGGCCACCGGCGCGTCCACCAGCAATCTGGCCATCATCC
TGATCGACGCGCGGCGCGGCGTGCAGACGCAAACCCGCCGCCATAGCTACATCGTCAGCCTGCTGGGCATCCGCCACGTG
ATCGTCGCGGTCAACAAGATGGACCTGGTGGATTACAGCGAGGACGTCTACAACCGCATCCGCGACGAATACCTGACCTT
CGCCGAGCATCTGGACATCCCTGACATCCATTTCGTGCCGATCTCCGCGCTGCGCGGCGACAACGTGGTCAGCCGCACCG
AGGCGGCGCCGTGGTACCAGGGCGCGACGCTGATGCACTTGCTGGAAACGGTGCAGATCAGCCACGATGCGCCTTTGTCC
GCCTTCCGCCTGCCGGTGCAATACGTGAACCGGCCGAATCTGGACTTCCGCGGCTTCTGCGGCACCATCGCCAGCGGTGC
CGTGCATCCGGGGGATGCTGTCGTGGCGCTGCCGTCGGGCAAGGAGAGCCGGGTCAAGGAGATCGTCACTTTCGACGGCA
GCCTGTCCCGCGCCGGAGCCGGCCAGGCGGTCACGCTGACGCTGGAGGACGAAATCGACATCTCCCGCGGCGACATGCTG
GTGCGCGCCGACGAGGCGCGGCCGCACGTGTCGCGCAGCTTCGACGCCCACCTGGTGGCGATGGGCGAGGCGCCGCTGCG
GCCGGGCAAGGAATACGGCTTCAAGCTGGCCGGCAAGTATGTGACCGGACGCATCGAAGCCATCCTGCATCGGACCGACG
TCAACACGCTGCAGGACAGTCCGGCCGACGCGCTGGCGCTGAACGAGATCGGCCTGTGCCGGATTTCGCTGAACAGCCCG
GCCGCGTTCGACGCATACCGCGACTGCCGCGGCAGCGGCAGCCTGATCCTGATCGACAGGCTGAGCAACGGCACGGTAGC
CGCAGGCATGATCGTCGCGCAAAGCGAAGAGGCGTCGCCGGCCGCGCTGTCGCCATGGGCGTTGTTCGAGCAGGAGCTGG
ACCAGCTGCTGCAGCGCTACTTCCCGCAGATGACGCGCGCTGAACTGGCGCGGCGCTTGCGGGACGAGCTCTGA

Upstream 100 bases:

>100_bases
AGGAAATGCTGCTGACGAGGACTTCCGAGCGGCAGGGCCGGCTGATCGACCATGACAGCGCCGGCTCGATGGAAAAGAAG
AAAATGGAAGGGTATTTCTG

Downstream 100 bases:

>100_bases
TTCCTCTCCCCGCAACAGCCCCGATTCCGGGGCTGTTTCTTTTCCGGTGCTTGGACGCCCGCTCAGAATCGGTCCTGGCC
GATGACGCTGCGCAGATTGT

Product: sulfate adenylyltransferase subunit 1

Products: NA

Alternate protein names: ATP-sulfurylase large subunit; Sulfate adenylate transferase; SAT

Number of amino acids: Translated: 477; Mature: 476

Protein sequence:

>477_residues
MSHQSELIAGDILEYLSQHENKDMLRFITCGSVDDGKSTLIGRLLHDSKLIFEDQLAAIERDSKKYNTTDQDIDLALLVD
GLQAEREQGITIDVAYRYFSTDKRKFIIADCPGHEQYTRNMATGASTSNLAIILIDARRGVQTQTRRHSYIVSLLGIRHV
IVAVNKMDLVDYSEDVYNRIRDEYLTFAEHLDIPDIHFVPISALRGDNVVSRTEAAPWYQGATLMHLLETVQISHDAPLS
AFRLPVQYVNRPNLDFRGFCGTIASGAVHPGDAVVALPSGKESRVKEIVTFDGSLSRAGAGQAVTLTLEDEIDISRGDML
VRADEARPHVSRSFDAHLVAMGEAPLRPGKEYGFKLAGKYVTGRIEAILHRTDVNTLQDSPADALALNEIGLCRISLNSP
AAFDAYRDCRGSGSLILIDRLSNGTVAAGMIVAQSEEASPAALSPWALFEQELDQLLQRYFPQMTRAELARRLRDEL

Sequences:

>Translated_477_residues
MSHQSELIAGDILEYLSQHENKDMLRFITCGSVDDGKSTLIGRLLHDSKLIFEDQLAAIERDSKKYNTTDQDIDLALLVD
GLQAEREQGITIDVAYRYFSTDKRKFIIADCPGHEQYTRNMATGASTSNLAIILIDARRGVQTQTRRHSYIVSLLGIRHV
IVAVNKMDLVDYSEDVYNRIRDEYLTFAEHLDIPDIHFVPISALRGDNVVSRTEAAPWYQGATLMHLLETVQISHDAPLS
AFRLPVQYVNRPNLDFRGFCGTIASGAVHPGDAVVALPSGKESRVKEIVTFDGSLSRAGAGQAVTLTLEDEIDISRGDML
VRADEARPHVSRSFDAHLVAMGEAPLRPGKEYGFKLAGKYVTGRIEAILHRTDVNTLQDSPADALALNEIGLCRISLNSP
AAFDAYRDCRGSGSLILIDRLSNGTVAAGMIVAQSEEASPAALSPWALFEQELDQLLQRYFPQMTRAELARRLRDEL
>Mature_476_residues
SHQSELIAGDILEYLSQHENKDMLRFITCGSVDDGKSTLIGRLLHDSKLIFEDQLAAIERDSKKYNTTDQDIDLALLVDG
LQAEREQGITIDVAYRYFSTDKRKFIIADCPGHEQYTRNMATGASTSNLAIILIDARRGVQTQTRRHSYIVSLLGIRHVI
VAVNKMDLVDYSEDVYNRIRDEYLTFAEHLDIPDIHFVPISALRGDNVVSRTEAAPWYQGATLMHLLETVQISHDAPLSA
FRLPVQYVNRPNLDFRGFCGTIASGAVHPGDAVVALPSGKESRVKEIVTFDGSLSRAGAGQAVTLTLEDEIDISRGDMLV
RADEARPHVSRSFDAHLVAMGEAPLRPGKEYGFKLAGKYVTGRIEAILHRTDVNTLQDSPADALALNEIGLCRISLNSPA
AFDAYRDCRGSGSLILIDRLSNGTVAAGMIVAQSEEASPAALSPWALFEQELDQLLQRYFPQMTRAELARRLRDEL

Specific function: May be the GTPase, regulating ATP sulfurylase activity

COG id: COG2895

COG function: function code P; GTPases - Sulfate adenylate transferase subunit 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. CysN/nodQ subfamily

Homologues:

Organism=Homo sapiens, GI223555963, Length=439, Percent_Identity=28.9293849658314, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI5729864, Length=439, Percent_Identity=28.9293849658314, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI194097354, Length=334, Percent_Identity=29.940119760479, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI194018520, Length=334, Percent_Identity=29.940119760479, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI194018522, Length=337, Percent_Identity=29.673590504451, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI46094014, Length=338, Percent_Identity=29.8816568047337, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI4503471, Length=463, Percent_Identity=27.4298056155508, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI4503475, Length=475, Percent_Identity=26.5263157894737, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI34147630, Length=316, Percent_Identity=31.6455696202532, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI157426893, Length=280, Percent_Identity=25, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI1789108, Length=456, Percent_Identity=58.3333333333333, Blast_Score=527, Evalue=1e-151,
Organism=Escherichia coli, GI1790412, Length=353, Percent_Identity=26.628895184136, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789737, Length=353, Percent_Identity=26.628895184136, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI2367247, Length=296, Percent_Identity=27.3648648648649, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI115532067, Length=431, Percent_Identity=29.4663573085847, Blast_Score=167, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI115532065, Length=431, Percent_Identity=29.4663573085847, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI32566629, Length=436, Percent_Identity=26.605504587156, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17552884, Length=350, Percent_Identity=29.1428571428571, Blast_Score=144, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17569207, Length=350, Percent_Identity=29.1428571428571, Blast_Score=144, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI32566303, Length=343, Percent_Identity=27.4052478134111, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI32566301, Length=149, Percent_Identity=30.8724832214765, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI25141371, Length=93, Percent_Identity=34.4086021505376, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17556456, Length=195, Percent_Identity=32.8205128205128, Blast_Score=73, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6325337, Length=446, Percent_Identity=28.2511210762332, Blast_Score=161, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6319594, Length=446, Percent_Identity=28.2511210762332, Blast_Score=161, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6322937, Length=383, Percent_Identity=29.5039164490862, Blast_Score=159, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6320377, Length=440, Percent_Identity=27.5, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6324761, Length=146, Percent_Identity=36.3013698630137, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6323320, Length=345, Percent_Identity=25.5072463768116, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45550900, Length=433, Percent_Identity=27.4826789838337, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI17137380, Length=339, Percent_Identity=27.7286135693215, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24652838, Length=347, Percent_Identity=28.2420749279539, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI17137572, Length=347, Percent_Identity=28.2420749279539, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI45553807, Length=350, Percent_Identity=28.5714285714286, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI45553816, Length=350, Percent_Identity=28.5714285714286, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24651721, Length=350, Percent_Identity=28.5714285714286, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI17864154, Length=350, Percent_Identity=28.5714285714286, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI281363316, Length=276, Percent_Identity=28.6231884057971, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI17864358, Length=276, Percent_Identity=28.6231884057971, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI19921738, Length=288, Percent_Identity=29.8611111111111, Blast_Score=86, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYSN_CHRVO (Q7NVN5)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_901977.1
- ProteinModelPortal:   Q7NVN5
- SMR:   Q7NVN5
- GeneID:   2549880
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_2307
- NMPDR:   fig|243365.1.peg.2307
- HOGENOM:   HBG307581
- OMA:   KELFFDP
- PhylomeDB:   Q7NVN5
- ProtClustDB:   CLSK2485475
- BioCyc:   CVIO243365:CV_2307-MONOMER
- BRENDA:   2.7.7.4
- HAMAP:   MF_00062
- InterPro:   IPR000795
- InterPro:   IPR011779
- InterPro:   IPR009001
- InterPro:   IPR004161
- InterPro:   IPR009000
- PRINTS:   PR00315
- TIGRFAMs:   TIGR02034

Pfam domain/function: PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2; SSF50465 Elong_init_C; SSF50447 Translat_factor

EC number: =2.7.7.4

Molecular weight: Translated: 52841; Mature: 52710

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00301 EFACTOR_GTP; PS00014 ER_TARGET

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHQSELIAGDILEYLSQHENKDMLRFITCGSVDDGKSTLIGRLLHDSKLIFEDQLAAIE
CCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
RDSKKYNTTDQDIDLALLVDGLQAEREQGITIDVAYRYFSTDKRKFIIADCPGHEQYTRN
CCCCCCCCCCCCCEEEEEECCHHHHHHCCCEEEEEEEEECCCCCEEEEEECCCCHHHHHH
MATGASTSNLAIILIDARRGVQTQTRRHSYIVSLLGIRHVIVAVNKMDLVDYSEDVYNRI
HHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHH
RDEYLTFAEHLDIPDIHFVPISALRGDNVVSRTEAAPWYQGATLMHLLETVQISHDAPLS
HHHHHHHHHHCCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHH
AFRLPVQYVNRPNLDFRGFCGTIASGAVHPGDAVVALPSGKESRVKEIVTFDGSLSRAGA
HHCCCHHHCCCCCCCCCHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHEEECCCCCCCCC
GQAVTLTLEDEIDISRGDMLVRADEARPHVSRSFDAHLVAMGEAPLRPGKEYGFKLAGKY
CCEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCHHCCEEEECHH
VTGRIEAILHRTDVNTLQDSPADALALNEIGLCRISLNSPAAFDAYRDCRGSGSLILIDR
HHHHEEEHHHHCCCCCCCCCCCCEEEECCCCEEEEECCCCCCHHHHHHCCCCCCEEEEEE
LSNGTVAAGMIVAQSEEASPAALSPWALFEQELDQLLQRYFPQMTRAELARRLRDEL
CCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SHQSELIAGDILEYLSQHENKDMLRFITCGSVDDGKSTLIGRLLHDSKLIFEDQLAAIE
CCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
RDSKKYNTTDQDIDLALLVDGLQAEREQGITIDVAYRYFSTDKRKFIIADCPGHEQYTRN
CCCCCCCCCCCCCEEEEEECCHHHHHHCCCEEEEEEEEECCCCCEEEEEECCCCHHHHHH
MATGASTSNLAIILIDARRGVQTQTRRHSYIVSLLGIRHVIVAVNKMDLVDYSEDVYNRI
HHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHH
RDEYLTFAEHLDIPDIHFVPISALRGDNVVSRTEAAPWYQGATLMHLLETVQISHDAPLS
HHHHHHHHHHCCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHH
AFRLPVQYVNRPNLDFRGFCGTIASGAVHPGDAVVALPSGKESRVKEIVTFDGSLSRAGA
HHCCCHHHCCCCCCCCCHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHEEECCCCCCCCC
GQAVTLTLEDEIDISRGDMLVRADEARPHVSRSFDAHLVAMGEAPLRPGKEYGFKLAGKY
CCEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCHHCCEEEECHH
VTGRIEAILHRTDVNTLQDSPADALALNEIGLCRISLNSPAAFDAYRDCRGSGSLILIDR
HHHHEEEHHHHCCCCCCCCCCCCEEEECCCCEEEEECCCCCCHHHHHHCCCCCCEEEEEE
LSNGTVAAGMIVAQSEEASPAALSPWALFEQELDQLLQRYFPQMTRAELARRLRDEL
CCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782