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The map label for this gene is fsr [C]

Identifier: 34497633

GI number: 34497633

Start: 2350284

End: 2351486

Strand: Direct

Name: fsr [C]

Synonym: CV_2178

Alternate gene names: 34497633

Gene position: 2350284-2351486 (Clockwise)

Preceding gene: 34497632

Following gene: 34497638

Centisome position: 49.47

GC content: 70.16

Gene sequence:

>1203_bases
ATGAATGATCCGAAATCCGCCGTTCTGCGCGCCGAGGCCGCAAGCGAAGACGCGCGGCTGCGCCGCCGCTCGCTGCTGGC
CGCCGGCGGCGCCCACGCAGTTCATGACGGCCTGACCGACCTGGTCTACGTGTTGCTGCCCATCTGGCAGGCGCAGTTCG
GCATCGGCTACGCGATGGTAGGTTTGCTGCGCGGCGCCTATTCCGGGGCGATGGCCGGTTTCCAGCTGCTGGCCAGCCGG
CTGGCGAAGCGCTGGGGGCGCAAGCGCATGCTGGTGGGCGGCACCGCGCTGGCCGGCGCGGCCTATCTGCTGGCCGGGCA
GGCTGGCGGCCTGGCGGTTCTGTTGCTGGCGCTGACGCTGGGAGGCCTGGGCGCCAGCGTCCAGCATCCGCTGGCGTCCT
CGCTGGTGGCGGACAGCCACGAGGCGGGGGGAGGCTCGCGGCAGGCGCTAGCGCAATACAATTTCGCCGGCGACATCGGC
AAGACCTTGATCCCAGCATTGACCGGCCTGCTGCTGACGGTGGCGAGCTGGCGGCTCAGCGTCAGCCTGATGGGGCTGCT
TGGCTTGCTTGCCGCGGCGCTGTTGTGGCGATGGGCGCCGGCGCGCTTGCCGGCCGCCTCGGGGACATCGGCGGCGCGCG
CGGCGGGGCGAGGTTCAAGGGGCGGTTTGCGCGCCTTGCTGGCCACCGGCGCGATAGACAGCGCGGCGAGGATGGGCTTT
CTGACGTTTTTGCCCTTCCTGTTGAAGAGCAAGGGCGCGGGCGCGGCGGGCATCGGCCTGGCCCTGTCGCTGTTATTCGT
CGGCGGCGCGTTCGGCAAGCTGTTCTGCGGCTACTTGGGCGCGCGCATCGGCATGGTGAGGACGGTGTGGCTGACCGAAG
GTCTGACGGCCTTGCTGATCGCGGCGGGCCTGGCGCTGCCTTTGCTTGGCATGATGGCGATGTTGCCGCTGCTGGGTCTG
GCGCTGAACGGCACTTCGTCGGTGCTGTACGGCACGGTGCCGGAACTGGCCGACGCCAGCGGCCGCGAGCACGCGTTCGC
CTTGTTCTACACCGGCACGATAGGCGGCGGCGCGCTGTCGCCGGTGCTGTTCGGCCGTCTGGGCGACGTGGCCGGCGTGC
CTGTCGCGATGCTGGCGCTGGCCGCCTTCCTGTTATTGACCCTGCCTTTGTCCTGGCAGGTGGGCAGGGATCTGGCGGCA
TGA

Upstream 100 bases:

>100_bases
AGCTATTGGTCGATGGCGGCGTCGGCAACGTGTGAATTGTTTATGACGTTTGTGTTTCGCGGCGCTAGAATGGTCCGCAT
TGAAATGGAAGCGTCATCCG

Downstream 100 bases:

>100_bases
AACGCCGGCAGCGGCCGGCGTTTCATGTGACGGAGGCTCAGGCGTCCAGGCCGTCCCGCACCATCTGCGCGGCGCGCAGC
ACCGCGCGCGCCTTGTTCTG

Product: transmembrane efflux protein

Products: fosmidomycin [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: Facilitator Superfamily Protein; Transmembrane Efflux Protein; Transporter-Like Membrane Protein; Facilitator Family Protein

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MNDPKSAVLRAEAASEDARLRRRSLLAAGGAHAVHDGLTDLVYVLLPIWQAQFGIGYAMVGLLRGAYSGAMAGFQLLASR
LAKRWGRKRMLVGGTALAGAAYLLAGQAGGLAVLLLALTLGGLGASVQHPLASSLVADSHEAGGGSRQALAQYNFAGDIG
KTLIPALTGLLLTVASWRLSVSLMGLLGLLAAALLWRWAPARLPAASGTSAARAAGRGSRGGLRALLATGAIDSAARMGF
LTFLPFLLKSKGAGAAGIGLALSLLFVGGAFGKLFCGYLGARIGMVRTVWLTEGLTALLIAAGLALPLLGMMAMLPLLGL
ALNGTSSVLYGTVPELADASGREHAFALFYTGTIGGGALSPVLFGRLGDVAGVPVAMLALAAFLLLTLPLSWQVGRDLAA

Sequences:

>Translated_400_residues
MNDPKSAVLRAEAASEDARLRRRSLLAAGGAHAVHDGLTDLVYVLLPIWQAQFGIGYAMVGLLRGAYSGAMAGFQLLASR
LAKRWGRKRMLVGGTALAGAAYLLAGQAGGLAVLLLALTLGGLGASVQHPLASSLVADSHEAGGGSRQALAQYNFAGDIG
KTLIPALTGLLLTVASWRLSVSLMGLLGLLAAALLWRWAPARLPAASGTSAARAAGRGSRGGLRALLATGAIDSAARMGF
LTFLPFLLKSKGAGAAGIGLALSLLFVGGAFGKLFCGYLGARIGMVRTVWLTEGLTALLIAAGLALPLLGMMAMLPLLGL
ALNGTSSVLYGTVPELADASGREHAFALFYTGTIGGGALSPVLFGRLGDVAGVPVAMLALAAFLLLTLPLSWQVGRDLAA
>Mature_400_residues
MNDPKSAVLRAEAASEDARLRRRSLLAAGGAHAVHDGLTDLVYVLLPIWQAQFGIGYAMVGLLRGAYSGAMAGFQLLASR
LAKRWGRKRMLVGGTALAGAAYLLAGQAGGLAVLLLALTLGGLGASVQHPLASSLVADSHEAGGGSRQALAQYNFAGDIG
KTLIPALTGLLLTVASWRLSVSLMGLLGLLAAALLWRWAPARLPAASGTSAARAAGRGSRGGLRALLATGAIDSAARMGF
LTFLPFLLKSKGAGAAGIGLALSLLFVGGAFGKLFCGYLGARIGMVRTVWLTEGLTALLIAAGLALPLLGMMAMLPLLGL
ALNGTSSVLYGTVPELADASGREHAFALFYTGTIGGGALSPVLFGRLGDVAGVPVAMLALAAFLLLTLPLSWQVGRDLAA

Specific function: Confers The Resistance Against Fosmidomycin. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 40604; Mature: 40604

Theoretical pI: Translated: 11.12; Mature: 11.12

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDPKSAVLRAEAASEDARLRRRSLLAAGGAHAVHDGLTDLVYVLLPIWQAQFGIGYAMV
CCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLLRGAYSGAMAGFQLLASRLAKRWGRKRMLVGGTALAGAAYLLAGQAGGLAVLLLALTL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHH
GGLGASVQHPLASSLVADSHEAGGGSRQALAQYNFAGDIGKTLIPALTGLLLTVASWRLS
CCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
VSLMGLLGLLAAALLWRWAPARLPAASGTSAARAAGRGSRGGLRALLATGAIDSAARMGF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHH
LTFLPFLLKSKGAGAAGIGLALSLLFVGGAFGKLFCGYLGARIGMVRTVWLTEGLTALLI
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGLALPLLGMMAMLPLLGLALNGTSSVLYGTVPELADASGREHAFALFYTGTIGGGALS
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHCCCCCCCEEEEEEECCCCCCHHH
PVLFGRLGDVAGVPVAMLALAAFLLLTLPLSWQVGRDLAA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCC
>Mature Secondary Structure
MNDPKSAVLRAEAASEDARLRRRSLLAAGGAHAVHDGLTDLVYVLLPIWQAQFGIGYAMV
CCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLLRGAYSGAMAGFQLLASRLAKRWGRKRMLVGGTALAGAAYLLAGQAGGLAVLLLALTL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHH
GGLGASVQHPLASSLVADSHEAGGGSRQALAQYNFAGDIGKTLIPALTGLLLTVASWRLS
CCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
VSLMGLLGLLAAALLWRWAPARLPAASGTSAARAAGRGSRGGLRALLATGAIDSAARMGF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHH
LTFLPFLLKSKGAGAAGIGLALSLLFVGGAFGKLFCGYLGARIGMVRTVWLTEGLTALLI
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGLALPLLGMMAMLPLLGLALNGTSSVLYGTVPELADASGREHAFALFYTGTIGGGALS
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHCCCCCCCEEEEEEECCCCCCHHH
PVLFGRLGDVAGVPVAMLALAAFLLLTLPLSWQVGRDLAA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: fosmidomycin [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: fosmidomycin [Cytoplasm] + Proton [Periplasm] = fosmidomycin [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA