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The map label for this gene is bvgS [H]

Identifier: 34497307

GI number: 34497307

Start: 2006736

End: 2008394

Strand: Reverse

Name: bvgS [H]

Synonym: CV_1852

Alternate gene names: 34497307

Gene position: 2008394-2006736 (Counterclockwise)

Preceding gene: 34497309

Following gene: 34497306

Centisome position: 42.27

GC content: 67.33

Gene sequence:

>1659_bases
CTGGAGATGGCCATCACCCGCATGCCTGAGCTGGATGGCATCGGCTTCAACATGACGCTGCGCGACATCTCTGCCCGCAA
GGCGGCCGAACAGGAGCTGCGCCGCGCCCACGATCAGGCCAACGCCGCCAATCAGGCCAAGACCGCCTTCCTCACCACCA
TCAGCCATGAGATACGCACGCCGATGAACGGCGTGCTGGGGATGCTGGAGTTGCTGCAGATGAGCCGCCTGGACGAGGAA
CAGCAGGACACGCTGGCCACGGCCCGCGAATCGGCTCAATTGCTGCTGAGGCTGATAGACGACATCCTGGACTTCGCCAA
AATAGAGGCGGACCAGATGGAAGTGGTGTACGCCGCCACCCCTATCCGCCCCCTGCTGCAACAGGTGCACAGCCTGTATG
CCCAGGCGGCCGAACGCAAGGGTCTGAGGATGGAGCTGGAGATGGACGACGCGCTGGCCGGCGCGCTGCGGGTCGACCCC
CTGCGCCTGCGCCAGGTGCTGCAGAACTTCCTCAGCAACGCGGTGAAATTCACGGCCACCGGCAGCGTGAAGCTTCGCGC
CGCGGTGGAAGCCGACGACGGCCGCCGCCAGCGGCTGCGCTTCGACGTGACGGATACCGGCATCGGCATGGACCGCGACC
AGCTGGCCCGGCTGTTCCAGCCCTTCACCCAGGCAGAGTCCGATACCGCCCGGCATTACGGCGGAGCCGGCCTGGGACTC
AGCATCAGCCGCCGCCTGGCGACGCTGATGGGCGGCGCGGTGGAGCTGCAGAGCGAGCTCGGCCTCGGAACCTGCGCGTC
GCTGCTACTTTCGGCGGACATCGCCGACGCGGCCGACATCCAGCCTACGCTGCCGCCCGCCCCCCGCGCCGTGGCCGCCC
ACGACGCGCCCCCCGCCGTGCTGCTGGTCGAGGACAACCCCACCAATCTCAAGCTGGCGAAACTGCAGCTGGAAAAGCTG
GGCTACCGCGTCGAATGCGCCGAAGACGGCGCCCAGGCCTTCGAGAAATGGCAACGCGGCCGTTACCAGCTGCTGTTGAC
CGACTGCCAGATGCCCAATGTGGACGGTTACCAGCTCTCCCGGCTGGTCCGCTCCTACGAGGCCGGCAATCCCCACCGGC
CCCGCATCCCCATCATCGCCTGCACCGCCAACTCCGGCGAGGCGGAGCAGGAGGCGACGGCGGCGGCCGGCATGGATGGC
TACCTGCTCAAACCGCTGGCGTTGTCGGAACTGGCCGAGATGCTGGAAAGCAAGCTGTACCCGCCATCCGCCGAGCGCCC
CGCGCCGCCGTTGCCCGCCCATGCGCCGCCGGTGAACCTGGCTACGCTCAGCCTCAGCTGCGAAGGCAACCGCAAACTGG
AAAACCGGCTGTTGACCGAGTTCCTGCTCAACGCCAGGCATGACATCGCCCGCATGCGCGCCGCGATCGCCAGCGGCAAT
CTGCAGCACCTGCGCGCCATATCCGACGGTCTGCGCGACAGCGCCGCGATTGTCGGCGCCGGCTTGATTTCCACTATGGC
CGCACTGATGGCGCAGGCTACCCGGGAGGGACAAATGGACAGCGCGCCCAGGCTGCTGCTTTTGCTGGAAGGATGCTGCC
GAGAGCTGGAGCAATGGTTGACCCAGCGCGAGGAAAGCGGCAGCCTGAGTCCAGGCTGA

Upstream 100 bases:

>100_bases
GGACGCGCTGATGTCCATCGTGCTGGGCGACGGCGACGCCGGCCAGCTCGGCCAGCTGCAGCAGCTGACCGCCGCGCGCG
CCGACGGCAGCCTGTTCCCG

Downstream 100 bases:

>100_bases
ACCGGAGCGAGCGGAACATGAAAGCGGACATGAAGGTCAGACGCCTGCTGGACAGCATCATCATCCGCCTGCTGGCGCTG
TCTCTGGCCATCATGATCAT

Product: sensory box histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MEMAITRMPELDGIGFNMTLRDISARKAAEQELRRAHDQANAANQAKTAFLTTISHEIRTPMNGVLGMLELLQMSRLDEE
QQDTLATARESAQLLLRLIDDILDFAKIEADQMEVVYAATPIRPLLQQVHSLYAQAAERKGLRMELEMDDALAGALRVDP
LRLRQVLQNFLSNAVKFTATGSVKLRAAVEADDGRRQRLRFDVTDTGIGMDRDQLARLFQPFTQAESDTARHYGGAGLGL
SISRRLATLMGGAVELQSELGLGTCASLLLSADIADAADIQPTLPPAPRAVAAHDAPPAVLLVEDNPTNLKLAKLQLEKL
GYRVECAEDGAQAFEKWQRGRYQLLLTDCQMPNVDGYQLSRLVRSYEAGNPHRPRIPIIACTANSGEAEQEATAAAGMDG
YLLKPLALSELAEMLESKLYPPSAERPAPPLPAHAPPVNLATLSLSCEGNRKLENRLLTEFLLNARHDIARMRAAIASGN
LQHLRAISDGLRDSAAIVGAGLISTMAALMAQATREGQMDSAPRLLLLLEGCCRELEQWLTQREESGSLSPG

Sequences:

>Translated_552_residues
MEMAITRMPELDGIGFNMTLRDISARKAAEQELRRAHDQANAANQAKTAFLTTISHEIRTPMNGVLGMLELLQMSRLDEE
QQDTLATARESAQLLLRLIDDILDFAKIEADQMEVVYAATPIRPLLQQVHSLYAQAAERKGLRMELEMDDALAGALRVDP
LRLRQVLQNFLSNAVKFTATGSVKLRAAVEADDGRRQRLRFDVTDTGIGMDRDQLARLFQPFTQAESDTARHYGGAGLGL
SISRRLATLMGGAVELQSELGLGTCASLLLSADIADAADIQPTLPPAPRAVAAHDAPPAVLLVEDNPTNLKLAKLQLEKL
GYRVECAEDGAQAFEKWQRGRYQLLLTDCQMPNVDGYQLSRLVRSYEAGNPHRPRIPIIACTANSGEAEQEATAAAGMDG
YLLKPLALSELAEMLESKLYPPSAERPAPPLPAHAPPVNLATLSLSCEGNRKLENRLLTEFLLNARHDIARMRAAIASGN
LQHLRAISDGLRDSAAIVGAGLISTMAALMAQATREGQMDSAPRLLLLLEGCCRELEQWLTQREESGSLSPG
>Mature_552_residues
MEMAITRMPELDGIGFNMTLRDISARKAAEQELRRAHDQANAANQAKTAFLTTISHEIRTPMNGVLGMLELLQMSRLDEE
QQDTLATARESAQLLLRLIDDILDFAKIEADQMEVVYAATPIRPLLQQVHSLYAQAAERKGLRMELEMDDALAGALRVDP
LRLRQVLQNFLSNAVKFTATGSVKLRAAVEADDGRRQRLRFDVTDTGIGMDRDQLARLFQPFTQAESDTARHYGGAGLGL
SISRRLATLMGGAVELQSELGLGTCASLLLSADIADAADIQPTLPPAPRAVAAHDAPPAVLLVEDNPTNLKLAKLQLEKL
GYRVECAEDGAQAFEKWQRGRYQLLLTDCQMPNVDGYQLSRLVRSYEAGNPHRPRIPIIACTANSGEAEQEATAAAGMDG
YLLKPLALSELAEMLESKLYPPSAERPAPPLPAHAPPVNLATLSLSCEGNRKLENRLLTEFLLNARHDIARMRAAIASGN
LQHLRAISDGLRDSAAIVGAGLISTMAALMAQATREGQMDSAPRLLLLLEGCCRELEQWLTQREESGSLSPG

Specific function: Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=423, Percent_Identity=37.1158392434988, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1788713, Length=420, Percent_Identity=32.8571428571429, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI87081816, Length=407, Percent_Identity=34.1523341523341, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI145693157, Length=246, Percent_Identity=36.9918699186992, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1789149, Length=244, Percent_Identity=36.8852459016393, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI87082128, Length=269, Percent_Identity=27.5092936802974, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1786600, Length=240, Percent_Identity=27.9166666666667, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788393, Length=213, Percent_Identity=27.2300469483568, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1786783, Length=221, Percent_Identity=27.1493212669683, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788549, Length=275, Percent_Identity=23.6363636363636, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1790436, Length=263, Percent_Identity=25.8555133079848, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1786912, Length=249, Percent_Identity=28.5140562248996, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1788279, Length=224, Percent_Identity=24.1071428571429, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788191, Length=116, Percent_Identity=35.3448275862069, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1787894, Length=229, Percent_Identity=30.1310043668122, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=72, Percent_Identity=41.6666666666667, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=116, Percent_Identity=34.4827586206897, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60175; Mature: 60175

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMAITRMPELDGIGFNMTLRDISARKAAEQELRRAHDQANAANQAKTAFLTTISHEIRT
CCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
PMNGVLGMLELLQMSRLDEEQQDTLATARESAQLLLRLIDDILDFAKIEADQMEVVYAAT
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
PIRPLLQQVHSLYAQAAERKGLRMELEMDDALAGALRVDPLRLRQVLQNFLSNAVKFTAT
CHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCHHHHHHHHHHHHHHHEEEEEC
GSVKLRAAVEADDGRRQRLRFDVTDTGIGMDRDQLARLFQPFTQAESDTARHYGGAGLGL
CCEEEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCH
SISRRLATLMGGAVELQSELGLGTCASLLLSADIADAADIQPTLPPAPRAVAAHDAPPAV
HHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCEE
LLVEDNPTNLKLAKLQLEKLGYRVECAEDGAQAFEKWQRGRYQLLLTDCQMPNVDGYQLS
EEEECCCCCEEHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHH
RLVRSYEAGNPHRPRIPIIACTANSGEAEQEATAAAGMDGYLLKPLALSELAEMLESKLY
HHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCCHHCCHHHHHHHHHHHHHCCC
PPSAERPAPPLPAHAPPVNLATLSLSCEGNRKLENRLLTEFLLNARHDIARMRAAIASGN
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LQHLRAISDGLRDSAAIVGAGLISTMAALMAQATREGQMDSAPRLLLLLEGCCRELEQWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
TQREESGSLSPG
HHHHCCCCCCCC
>Mature Secondary Structure
MEMAITRMPELDGIGFNMTLRDISARKAAEQELRRAHDQANAANQAKTAFLTTISHEIRT
CCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
PMNGVLGMLELLQMSRLDEEQQDTLATARESAQLLLRLIDDILDFAKIEADQMEVVYAAT
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
PIRPLLQQVHSLYAQAAERKGLRMELEMDDALAGALRVDPLRLRQVLQNFLSNAVKFTAT
CHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCHHHHHHHHHHHHHHHEEEEEC
GSVKLRAAVEADDGRRQRLRFDVTDTGIGMDRDQLARLFQPFTQAESDTARHYGGAGLGL
CCEEEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCH
SISRRLATLMGGAVELQSELGLGTCASLLLSADIADAADIQPTLPPAPRAVAAHDAPPAV
HHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCEE
LLVEDNPTNLKLAKLQLEKLGYRVECAEDGAQAFEKWQRGRYQLLLTDCQMPNVDGYQLS
EEEECCCCCEEHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHH
RLVRSYEAGNPHRPRIPIIACTANSGEAEQEATAAAGMDGYLLKPLALSELAEMLESKLY
HHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCCHHCCHHHHHHHHHHHHHCCC
PPSAERPAPPLPAHAPPVNLATLSLSCEGNRKLENRLLTEFLLNARHDIARMRAAIASGN
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LQHLRAISDGLRDSAAIVGAGLISTMAALMAQATREGQMDSAPRLLLLLEGCCRELEQWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
TQREESGSLSPG
HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1791760; 12910271 [H]