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The map label for this gene is gst3 [H]

Identifier: 34497230

GI number: 34497230

Start: 1931509

End: 1932123

Strand: Reverse

Name: gst3 [H]

Synonym: CV_1775

Alternate gene names: 34497230

Gene position: 1932123-1931509 (Counterclockwise)

Preceding gene: 34497231

Following gene: 34497229

Centisome position: 40.67

GC content: 69.76

Gene sequence:

>615_bases
ATGTCCCCCGCCGACATCAAACTGTACGATTTCGCCCTGTCCGGCCACAGCCACCGCGCCCGGCTGATGCTGTCGCTGCT
GGACCTGGAGTACGAAGCCGTTCCGGTCAATCTGCGCGAAGGCGAGCATAAACAGCCGGCCTTCCTCAAGCTGAACCGTT
TCGGCCAGATTCCGGTGCTGGTCGATGGCGACGAGGTCATCGCCGACTCCAACGCCATCCTGGTCTACCTGGCGCGCCGC
TACGGCCACGGCGACTGGCTGCCGTCCGATCCCGTCCGCGAAGCCCGCGTCCAGCGCTGGCTGTCCGCCGCCGCCGGCCC
GCTGGCCTTCGGCGCCGCCCAGGCGCGGCTGCACAAATGGCGCGGCGTGCCGCTGGACTACGAACTGGCCGCCAGCCGAG
CCAGGGCGCTTCTCCAGGTGATGGACGAGGAGTTGGCCGAACGCCCCTTCCTGGCCGGCGACGCCGCCACCATCGCCGAC
GTCGCGCTCTACACCTACACCGCGCACGCGCCGGAAGGCGACATTCCGTTGGCGCCGTATCCGCATGTCCGCGCCTGGCT
GGCCCGCGTCGAGGCGCTGCCCGGCTTCGTGGCGATGCCGCCCGCCAACGCTTAA

Upstream 100 bases:

>100_bases
AGATAATGGAATAATCCATTGTCCTTGACGGCGATTCAGCTTTTAACCGCCATCAGGCAAAGTCGTGGCCGTGTTCCGCT
TCCGCCACAAGGAGAAAAGC

Downstream 100 bases:

>100_bases
ATGACAGGAACCGCGAATGTCCGACTCCCCTCCCATCCCCTGGCACTCCGGCGAACGGGAAATGCAACGCCGCGCCGGCA
GCCTGGAGCACATGGCGGCG

Product: glutathione S-transferase family protein

Products: HX; R-S-glutathione

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MSPADIKLYDFALSGHSHRARLMLSLLDLEYEAVPVNLREGEHKQPAFLKLNRFGQIPVLVDGDEVIADSNAILVYLARR
YGHGDWLPSDPVREARVQRWLSAAAGPLAFGAAQARLHKWRGVPLDYELAASRARALLQVMDEELAERPFLAGDAATIAD
VALYTYTAHAPEGDIPLAPYPHVRAWLARVEALPGFVAMPPANA

Sequences:

>Translated_204_residues
MSPADIKLYDFALSGHSHRARLMLSLLDLEYEAVPVNLREGEHKQPAFLKLNRFGQIPVLVDGDEVIADSNAILVYLARR
YGHGDWLPSDPVREARVQRWLSAAAGPLAFGAAQARLHKWRGVPLDYELAASRARALLQVMDEELAERPFLAGDAATIAD
VALYTYTAHAPEGDIPLAPYPHVRAWLARVEALPGFVAMPPANA
>Mature_203_residues
SPADIKLYDFALSGHSHRARLMLSLLDLEYEAVPVNLREGEHKQPAFLKLNRFGQIPVLVDGDEVIADSNAILVYLARRY
GHGDWLPSDPVREARVQRWLSAAAGPLAFGAAQARLHKWRGVPLDYELAASRARALLQVMDEELAERPFLAGDAATIADV
ALYTYTAHAPEGDIPLAPYPHVRAWLARVEALPGFVAMPPANA

Specific function: Unknown

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI4504187, Length=170, Percent_Identity=34.7058823529412, Blast_Score=80, Evalue=9e-16,
Organism=Homo sapiens, GI124249394, Length=170, Percent_Identity=34.7058823529412, Blast_Score=80, Evalue=9e-16,
Organism=Homo sapiens, GI167466164, Length=179, Percent_Identity=32.9608938547486, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI22202624, Length=200, Percent_Identity=28, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI87082195, Length=187, Percent_Identity=27.807486631016, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788640, Length=201, Percent_Identity=29.3532338308458, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87081789, Length=182, Percent_Identity=25.8241758241758, Blast_Score=60, Evalue=9e-11,
Organism=Drosophila melanogaster, GI19922526, Length=202, Percent_Identity=34.1584158415842, Blast_Score=90, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24654965, Length=183, Percent_Identity=35.5191256830601, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24654979, Length=197, Percent_Identity=35.0253807106599, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI19922932, Length=199, Percent_Identity=32.6633165829146, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17864594, Length=192, Percent_Identity=30.7291666666667, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17864598, Length=164, Percent_Identity=35.3658536585366, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17933730, Length=194, Percent_Identity=26.8041237113402, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17864596, Length=205, Percent_Identity=27.8048780487805, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI221378983, Length=172, Percent_Identity=33.1395348837209, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19922528, Length=192, Percent_Identity=31.25, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646259, Length=172, Percent_Identity=33.1395348837209, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17864592, Length=174, Percent_Identity=30.4597701149425, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24654992, Length=186, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20130115, Length=182, Percent_Identity=31.3186813186813, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI19922160, Length=190, Percent_Identity=32.1052631578947, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20130123, Length=187, Percent_Identity=32.620320855615, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24654975, Length=184, Percent_Identity=33.1521739130435, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28571670, Length=172, Percent_Identity=27.906976744186, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI19922532, Length=183, Percent_Identity=29.5081967213115, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI85725204, Length=164, Percent_Identity=31.0975609756098, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17737923, Length=164, Percent_Identity=31.0975609756098, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45549270, Length=196, Percent_Identity=30.1020408163265, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24654983, Length=186, Percent_Identity=31.1827956989247, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI20129811, Length=177, Percent_Identity=29.3785310734463, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24654996, Length=189, Percent_Identity=31.2169312169312, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: 2.5.1.18

Molecular weight: Translated: 22439; Mature: 22308

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPADIKLYDFALSGHSHRARLMLSLLDLEYEAVPVNLREGEHKQPAFLKLNRFGQIPVL
CCCCCEEEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEECCCCCCCEE
VDGDEVIADSNAILVYLARRYGHGDWLPSDPVREARVQRWLSAAAGPLAFGAAQARLHKW
ECCCCEEECCCEEEEEEEHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RGVPLDYELAASRARALLQVMDEELAERPFLAGDAATIADVALYTYTAHAPEGDIPLAPY
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEECCCCCCCCCCCCC
PHVRAWLARVEALPGFVAMPPANA
HHHHHHHHHHHHCCCEEECCCCCC
>Mature Secondary Structure 
SPADIKLYDFALSGHSHRARLMLSLLDLEYEAVPVNLREGEHKQPAFLKLNRFGQIPVL
CCCCEEEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEECCCCCCCEE
VDGDEVIADSNAILVYLARRYGHGDWLPSDPVREARVQRWLSAAAGPLAFGAAQARLHKW
ECCCCEEECCCEEEEEEEHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RGVPLDYELAASRARALLQVMDEELAERPFLAGDAATIADVALYTYTAHAPEGDIPLAPY
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEECCCCCCCCCCCCC
PHVRAWLARVEALPGFVAMPPANA
HHHHHHHHHHHHCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; glutathione

Specific reaction: RX + glutathione = HX + R-S-glutathione

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA