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The map label for this gene is 34497025

Identifier: 34497025

GI number: 34497025

Start: 1683036

End: 1684943

Strand: Reverse

Name: 34497025

Synonym: CV_1570

Alternate gene names: NA

Gene position: 1684943-1683036 (Counterclockwise)

Preceding gene: 34497026

Following gene: 34497024

Centisome position: 35.46

GC content: 72.38

Gene sequence:

>1908_bases
ATGAGTCCGATCTACCCCTTCGCCGCCATCGTCGGCCAAGAGCAATTGAAACAGGCGCTGCTGATCTGCGCGGTGGACCC
CACCGTCGGCGGCGTGCTGGTGCGCGGCGACAAGGGCAGCGCCAAGAGCACCGCCGCGCGCGGCCTGGCCGCCGTGCTGC
CGCCTATCCGCCGCGCCGCCGGCTGCGGCTACAACTGCGAGCCGGACCACCCGCTGCCGCTATGCCCGGTATGCTCCGGC
GGCGCGCGCGAGCTGCATGACGGCCCGGTGCCCTTCATCAACCTGCCACTGGGCGCCACCGAAGACCGGGTGCTGGGCAG
CCTGGACTTCGAAAAGGCGCTGCAAGGCGGCAAGCAGGCGTTCAAGCCCGGCCTGTTGGCCGGAGCCCACCGCGGCATGC
TGTATATCGACGAAGTGAACCTGCTGGCCGACCACCTGGTGGACGTGCTGCTGGACGCCGCCGCGATGGGCGTCAACACC
GTCGAGCGCGAGGGGCTGGCGGTCAGCCACCCGGCGCGGGTGACGCTGCTCGGCACCATGAACCAGGAAGAAGGCGATCT
GCGGCCGCAGTTGCTGGACCGCTTCGGCCTGATGGTGGACGTGGCCGCGCCGCGCGAGCCTGGCTTGCGCGCCGAAGTGG
TGCGGCGCCGCCTGGCCTTCGAGGCCGACCCGGCCGGCTTCGCCGCCCAGTGGCAAACCGACAGCGAGGCGCTGCGCGAA
AACATCGCCGCCGCGCGCGCGCTGCTGCCGCACACCCGGCTCAGCGACCAATTATTTCACTTCGTCAGCGAGCTGTGCTG
TGAATTCGAAGTCAGCAGCCTGCGCGCCGACATCGTGCTGAACAAGGCCGCACGCGCGCTGGCCGCGCTGGACGGCCGCA
TTGACGCCTCTGCCGAAGACATCCGCGACGCCGCCCGGCTGGTGCTGCCGCACCGCCGCCGCCGCAAGCCTTTCGAGCAG
AGCGGGCTGGACCAGGACAAGCTGGAGCGGATGACGCGGCAGGCGTCCACGCCGCCTCCGCTGCCGCAGGACCAGGGCGA
GGCCACGCAGCCGCCGCCGGACGCCGACGGCGAGCAGGAGCCGAAGCCTACCGGCCATGGTTCGGAGCAGATCTTCGCCG
CCGCGCCGGCCGGCGACATCGCCCGCATCCGCGTCCAGGCGCCGTCGACTGGCGACGCGGCCGGCCGCCGCAGCGACGGC
GCCAGCCGCCAGCGCGGACATTACGTGCGCGCCGAGGCCAATCCGCAGCCGGCCCAGCTGGCGGTGGACGCCACGCTGCG
CCACGCGATCTTGCGCGATCCGGACCACTTCGCCGTCACCCGCGCCGACCTGCACGACAAGGTCCGCGTCGCCAAGCAGG
GCAACCTGATCCTGCTGGTGGTGGACGCGTCGGGATCGATGGCCGCGCGCCAGCGGATGGAGCAGGTCAAGGGCACGGTG
CTGAGCCTCTTGGAAGACGCCTACCGCCGCCGCGACCAGGTGGCGCTGATCGCCTTCCGCGGCCAAAAGGCCGAGCTGTT
GCTGCCGCCGTGCAACCGCGTCGAACAAGCCGAAGCCGCGCTGCGCGAGCTGCCCACCGGCGGCCGCACGCCGCTGGCGC
ACGCGCTGGCGCTGGCCGCCGACACGCTGTCCCGCCAGCTCGGCGGCCCGGCGCCGCTCTTGGTCATCCTCAGCGACGGC
CGCGCCAATGTGGCGCTGGACGGCGACGGCGACCCGTGGCGGCAGGCGCTGGACCTGGCCGGCCAGCTGGCCGGCGCGCC
GGCGCTGGTGCTGGACACCGAACAGGACTTCGTCCGCCTGGGCCGCGCCCGCGAGCTGGCCGAGGCCCTGGGCGCGGAAT
ACCTGGCTTGCGACGCCCTCACCGGCGAGCAGCTGACATTGACGATTCAACAAAGACTGGGCCGCTGA

Upstream 100 bases:

>100_bases
GCCAGCTGTGGGCGGAGCCGGACCCAGCCACGCTGGCCGCCCTGCAACAGCTGCATCTGGATAGCGAAGCGCTGCTGGAA
GCGCGCGGAGAGAACAAAGC

Downstream 100 bases:

>100_bases
AATGACGGGCAAGGTTTACCTGATAGGCGCCGGCCCCGGCGACCTGGACATGCTGACGCTGAAGGCCGCGCGCTGCCTGC
AGCTGGCCGACGTGGCGCTG

Product: chelatase protein

Products: ADP; phosphate; Mg-protoporphyrin IX; H+

Alternate protein names: NA

Number of amino acids: Translated: 635; Mature: 634

Protein sequence:

>635_residues
MSPIYPFAAIVGQEQLKQALLICAVDPTVGGVLVRGDKGSAKSTAARGLAAVLPPIRRAAGCGYNCEPDHPLPLCPVCSG
GARELHDGPVPFINLPLGATEDRVLGSLDFEKALQGGKQAFKPGLLAGAHRGMLYIDEVNLLADHLVDVLLDAAAMGVNT
VEREGLAVSHPARVTLLGTMNQEEGDLRPQLLDRFGLMVDVAAPREPGLRAEVVRRRLAFEADPAGFAAQWQTDSEALRE
NIAAARALLPHTRLSDQLFHFVSELCCEFEVSSLRADIVLNKAARALAALDGRIDASAEDIRDAARLVLPHRRRRKPFEQ
SGLDQDKLERMTRQASTPPPLPQDQGEATQPPPDADGEQEPKPTGHGSEQIFAAAPAGDIARIRVQAPSTGDAAGRRSDG
ASRQRGHYVRAEANPQPAQLAVDATLRHAILRDPDHFAVTRADLHDKVRVAKQGNLILLVVDASGSMAARQRMEQVKGTV
LSLLEDAYRRRDQVALIAFRGQKAELLLPPCNRVEQAEAALRELPTGGRTPLAHALALAADTLSRQLGGPAPLLVILSDG
RANVALDGDGDPWRQALDLAGQLAGAPALVLDTEQDFVRLGRARELAEALGAEYLACDALTGEQLTLTIQQRLGR

Sequences:

>Translated_635_residues
MSPIYPFAAIVGQEQLKQALLICAVDPTVGGVLVRGDKGSAKSTAARGLAAVLPPIRRAAGCGYNCEPDHPLPLCPVCSG
GARELHDGPVPFINLPLGATEDRVLGSLDFEKALQGGKQAFKPGLLAGAHRGMLYIDEVNLLADHLVDVLLDAAAMGVNT
VEREGLAVSHPARVTLLGTMNQEEGDLRPQLLDRFGLMVDVAAPREPGLRAEVVRRRLAFEADPAGFAAQWQTDSEALRE
NIAAARALLPHTRLSDQLFHFVSELCCEFEVSSLRADIVLNKAARALAALDGRIDASAEDIRDAARLVLPHRRRRKPFEQ
SGLDQDKLERMTRQASTPPPLPQDQGEATQPPPDADGEQEPKPTGHGSEQIFAAAPAGDIARIRVQAPSTGDAAGRRSDG
ASRQRGHYVRAEANPQPAQLAVDATLRHAILRDPDHFAVTRADLHDKVRVAKQGNLILLVVDASGSMAARQRMEQVKGTV
LSLLEDAYRRRDQVALIAFRGQKAELLLPPCNRVEQAEAALRELPTGGRTPLAHALALAADTLSRQLGGPAPLLVILSDG
RANVALDGDGDPWRQALDLAGQLAGAPALVLDTEQDFVRLGRARELAEALGAEYLACDALTGEQLTLTIQQRLGR
>Mature_634_residues
SPIYPFAAIVGQEQLKQALLICAVDPTVGGVLVRGDKGSAKSTAARGLAAVLPPIRRAAGCGYNCEPDHPLPLCPVCSGG
ARELHDGPVPFINLPLGATEDRVLGSLDFEKALQGGKQAFKPGLLAGAHRGMLYIDEVNLLADHLVDVLLDAAAMGVNTV
EREGLAVSHPARVTLLGTMNQEEGDLRPQLLDRFGLMVDVAAPREPGLRAEVVRRRLAFEADPAGFAAQWQTDSEALREN
IAAARALLPHTRLSDQLFHFVSELCCEFEVSSLRADIVLNKAARALAALDGRIDASAEDIRDAARLVLPHRRRRKPFEQS
GLDQDKLERMTRQASTPPPLPQDQGEATQPPPDADGEQEPKPTGHGSEQIFAAAPAGDIARIRVQAPSTGDAAGRRSDGA
SRQRGHYVRAEANPQPAQLAVDATLRHAILRDPDHFAVTRADLHDKVRVAKQGNLILLVVDASGSMAARQRMEQVKGTVL
SLLEDAYRRRDQVALIAFRGQKAELLLPPCNRVEQAEAALRELPTGGRTPLAHALALAADTLSRQLGGPAPLLVILSDGR
ANVALDGDGDPWRQALDLAGQLAGAPALVLDTEQDFVRLGRARELAEALGAEYLACDALTGEQLTLTIQQRLGR

Specific function: Unknown

COG id: COG1239

COG function: function code H; Mg-chelatase subunit ChlI

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 VWFA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011704
- InterPro:   IPR012804
- InterPro:   IPR002035 [H]

Pfam domain/function: PF07728 AAA_5; PF00092 VWA [H]

EC number: 6.6.1.1

Molecular weight: Translated: 67999; Mature: 67868

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50234 VWFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPIYPFAAIVGQEQLKQALLICAVDPTVGGVLVRGDKGSAKSTAARGLAAVLPPIRRAA
CCCCCHHHHHHCHHHHHHHHEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
GCGYNCEPDHPLPLCPVCSGGARELHDGPVPFINLPLGATEDRVLGSLDFEKALQGGKQA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHCCCCHHHHHHCCHHH
FKPGLLAGAHRGMLYIDEVNLLADHLVDVLLDAAAMGVNTVEREGLAVSHPARVTLLGTM
HCCCHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHCCEEECCCCEEEEEECC
NQEEGDLRPQLLDRFGLMVDVAAPREPGLRAEVVRRRLAFEADPAGFAAQWQTDSEALRE
CCCCCCCCHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCCHHHHHH
NIAAARALLPHTRLSDQLFHFVSELCCEFEVSSLRADIVLNKAARALAALDGRIDASAED
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
IRDAARLVLPHRRRRKPFEQSGLDQDKLERMTRQASTPPPLPQDQGEATQPPPDADGEQE
HHHHHHHHCCHHHHCCCHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
PKPTGHGSEQIFAAAPAGDIARIRVQAPSTGDAAGRRSDGASRQRGHYVRAEANPQPAQL
CCCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCE
AVDATLRHAILRDPDHFAVTRADLHDKVRVAKQGNLILLVVDASGSMAARQRMEQVKGTV
EHHHHHHHHHHCCCCHHEEEHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHH
LSLLEDAYRRRDQVALIAFRGQKAELLLPPCNRVEQAEAALRELPTGGRTPLAHALALAA
HHHHHHHHHCCCCEEEEEEECCCCEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHH
DTLSRQLGGPAPLLVILSDGRANVALDGDGDPWRQALDLAGQLAGAPALVLDTEQDFVRL
HHHHHHHCCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEECHHHHHHH
GRARELAEALGAEYLACDALTGEQLTLTIQQRLGR
HHHHHHHHHHCCCEEEEECCCCCEEEEEHHHHHCC
>Mature Secondary Structure 
SPIYPFAAIVGQEQLKQALLICAVDPTVGGVLVRGDKGSAKSTAARGLAAVLPPIRRAA
CCCCHHHHHHCHHHHHHHHEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
GCGYNCEPDHPLPLCPVCSGGARELHDGPVPFINLPLGATEDRVLGSLDFEKALQGGKQA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHCCCCHHHHHHCCHHH
FKPGLLAGAHRGMLYIDEVNLLADHLVDVLLDAAAMGVNTVEREGLAVSHPARVTLLGTM
HCCCHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHCCEEECCCCEEEEEECC
NQEEGDLRPQLLDRFGLMVDVAAPREPGLRAEVVRRRLAFEADPAGFAAQWQTDSEALRE
CCCCCCCCHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCCHHHHHH
NIAAARALLPHTRLSDQLFHFVSELCCEFEVSSLRADIVLNKAARALAALDGRIDASAED
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
IRDAARLVLPHRRRRKPFEQSGLDQDKLERMTRQASTPPPLPQDQGEATQPPPDADGEQE
HHHHHHHHCCHHHHCCCHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
PKPTGHGSEQIFAAAPAGDIARIRVQAPSTGDAAGRRSDGASRQRGHYVRAEANPQPAQL
CCCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCE
AVDATLRHAILRDPDHFAVTRADLHDKVRVAKQGNLILLVVDASGSMAARQRMEQVKGTV
EHHHHHHHHHHCCCCHHEEEHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHH
LSLLEDAYRRRDQVALIAFRGQKAELLLPPCNRVEQAEAALRELPTGGRTPLAHALALAA
HHHHHHHHHCCCCEEEEEEECCCCEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHH
DTLSRQLGGPAPLLVILSDGRANVALDGDGDPWRQALDLAGQLAGAPALVLDTEQDFVRL
HHHHHHHCCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEECHHHHHHH
GRARELAEALGAEYLACDALTGEQLTLTIQQRLGR
HHHHHHHHHHCCCEEEEECCCCCEEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; protoporphyrin IX; Mg2+; H2O

Specific reaction: ATP + protoporphyrin IX + Mg2+ + H2O = ADP + phosphate + Mg-protoporphyrin IX + 2 H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]