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The map label for this gene is aroF [H]

Identifier: 34496936

GI number: 34496936

Start: 1578470

End: 1579576

Strand: Reverse

Name: aroF [H]

Synonym: CV_1481

Alternate gene names: 34496936

Gene position: 1579576-1578470 (Counterclockwise)

Preceding gene: 34496937

Following gene: 34496927

Centisome position: 33.25

GC content: 69.74

Gene sequence:

>1107_bases
ATGACAACGCTTGCCAGGCCGGAACACGGCCTACTCGCGCCCGAACACGGCCACGCGTCGCCGCCGTCCAGCCAGGCGGA
CTACCGCGCGATGGCCAGCCCCGCCGAACTATTGCGCAGCCTGCCGGCCGGCCCGCGCGCCAGCGCCTCGGTCCATTCCG
GCCGCGAGGCGGTGAAACGCGTACTGAGCGGAGCAGATCCGCGCTGGCTGGTGGTGGTGGGCCCCTGCTCCATCCACGAC
CCGCGCGCCGGCCTGGACTACGCCGCCCGGCTGGCGGACCTCGCCTCCGAGCTGGACGACACGCTGCTGATCGTGATGCG
CGCCTACTTCGAAAAGCCGCGCACCAGCGTGGGCTGGAAGGGCCTGATCAACGATCCCTACATGGACGACAGCTATTGCG
TGGACGAGGGCATGCACATCGCCCGCCGCTTCCTTTTGGCCGCCGCCGAACTGGGCCTGCCGCTGGCCGGCGAGGCGCTG
GACCCGATGTCGCCGCTGTATCTGGCCGACCTCTATAGCTGGATGGCGATCGGCGCGCGCACCACCGAATCGCAAATCCA
CCGCGAGCTGGCCTCGGCGCTGGACAGCGCCGTCGGATTCAAGAACAGCACCGACGGCTCGCTGGACGCGGCGCTCAACG
CCATCGTCTCCGCCAGCGCGCCGCACGCCTACCTCGGCATGGGCAAGGACGGCCGGGTGGCGGTGGTGAACAGCCGCGGC
AACCCGCACTGCCACCTGGTGCTGCGCGGCGGCGGCGGCCGGCCCAATTACGACTCGGTGAGCATCGCGCTGGCCGAGCA
GGCAATGAAGAAGCACGACATTCCGCCCGCCATCATGGTGGACTGCGCGCACGCCAACTCATGGAAGCAGCACACGCTGC
AGCCGCGCGTGCTGGCCGACGCGGTGTCCCAGATCCGCCACGGCAACCGCAGCATCCGCGCCTTCATGCTGGAGAGCTTC
ATCGAAGCCGGCAACCAGTCCATCCCGGCCGATCTGTCGCAGCTGCGCTACGGCTGCTCGGTGACCGATCCCTGCGTCGA
CTGGCACACCACCGCCGACATCCTGCGCGACGCGCGCGCCAAGCTGCGGCCGCTGCTGGAAAGCTGA

Upstream 100 bases:

>100_bases
GCCCTGTCGCCGACATCGGGGCCAGGCCTTGACGCCGGCCCTGCCGCAAACGACGGGCTGAATCCGCTGCTCGTTTGCGG
ATCATCCTGTGGAGAACATC

Downstream 100 bases:

>100_bases
GCCGCATCCGCAAGCCATGCCCTCCCGGCATGGTGAAGCGCGGCGCGAAAACTGAGCGCCATTGTGCGCGATAATTGGTG
TTCGAGATTGTTTCACAAGC

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MTTLARPEHGLLAPEHGHASPPSSQADYRAMASPAELLRSLPAGPRASASVHSGREAVKRVLSGADPRWLVVVGPCSIHD
PRAGLDYAARLADLASELDDTLLIVMRAYFEKPRTSVGWKGLINDPYMDDSYCVDEGMHIARRFLLAAAELGLPLAGEAL
DPMSPLYLADLYSWMAIGARTTESQIHRELASALDSAVGFKNSTDGSLDAALNAIVSASAPHAYLGMGKDGRVAVVNSRG
NPHCHLVLRGGGGRPNYDSVSIALAEQAMKKHDIPPAIMVDCAHANSWKQHTLQPRVLADAVSQIRHGNRSIRAFMLESF
IEAGNQSIPADLSQLRYGCSVTDPCVDWHTTADILRDARAKLRPLLES

Sequences:

>Translated_368_residues
MTTLARPEHGLLAPEHGHASPPSSQADYRAMASPAELLRSLPAGPRASASVHSGREAVKRVLSGADPRWLVVVGPCSIHD
PRAGLDYAARLADLASELDDTLLIVMRAYFEKPRTSVGWKGLINDPYMDDSYCVDEGMHIARRFLLAAAELGLPLAGEAL
DPMSPLYLADLYSWMAIGARTTESQIHRELASALDSAVGFKNSTDGSLDAALNAIVSASAPHAYLGMGKDGRVAVVNSRG
NPHCHLVLRGGGGRPNYDSVSIALAEQAMKKHDIPPAIMVDCAHANSWKQHTLQPRVLADAVSQIRHGNRSIRAFMLESF
IEAGNQSIPADLSQLRYGCSVTDPCVDWHTTADILRDARAKLRPLLES
>Mature_367_residues
TTLARPEHGLLAPEHGHASPPSSQADYRAMASPAELLRSLPAGPRASASVHSGREAVKRVLSGADPRWLVVVGPCSIHDP
RAGLDYAARLADLASELDDTLLIVMRAYFEKPRTSVGWKGLINDPYMDDSYCVDEGMHIARRFLLAAAELGLPLAGEALD
PMSPLYLADLYSWMAIGARTTESQIHRELASALDSAVGFKNSTDGSLDAALNAIVSASAPHAYLGMGKDGRVAVVNSRGN
PHCHLVLRGGGGRPNYDSVSIALAEQAMKKHDIPPAIMVDCAHANSWKQHTLQPRVLADAVSQIRHGNRSIRAFMLESFI
EAGNQSIPADLSQLRYGCSVTDPCVDWHTTADILRDARAKLRPLLES

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=336, Percent_Identity=50.297619047619, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1786969, Length=330, Percent_Identity=50.3030303030303, Blast_Score=335, Evalue=4e-93,
Organism=Escherichia coli, GI1787996, Length=330, Percent_Identity=46.0606060606061, Blast_Score=305, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6319726, Length=340, Percent_Identity=46.4705882352941, Blast_Score=315, Evalue=9e-87,
Organism=Saccharomyces cerevisiae, GI6320240, Length=352, Percent_Identity=42.6136363636364, Blast_Score=301, Evalue=1e-82,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 39631; Mature: 39500

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLARPEHGLLAPEHGHASPPSSQADYRAMASPAELLRSLPAGPRASASVHSGREAVKR
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHHH
VLSGADPRWLVVVGPCSIHDPRAGLDYAARLADLASELDDTLLIVMRAYFEKPRTSVGWK
HHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GLINDPYMDDSYCVDEGMHIARRFLLAAAELGLPLAGEALDPMSPLYLADLYSWMAIGAR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
TTESQIHRELASALDSAVGFKNSTDGSLDAALNAIVSASAPHAYLGMGKDGRVAVVNSRG
CHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCEEEEECCC
NPHCHLVLRGGGGRPNYDSVSIALAEQAMKKHDIPPAIMVDCAHANSWKQHTLQPRVLAD
CCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHCCCHHHHHH
AVSQIRHGNRSIRAFMLESFIEAGNQSIPADLSQLRYGCSVTDPCVDWHTTADILRDARA
HHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
KLRPLLES
HHHHHHCC
>Mature Secondary Structure 
TTLARPEHGLLAPEHGHASPPSSQADYRAMASPAELLRSLPAGPRASASVHSGREAVKR
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHHH
VLSGADPRWLVVVGPCSIHDPRAGLDYAARLADLASELDDTLLIVMRAYFEKPRTSVGWK
HHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GLINDPYMDDSYCVDEGMHIARRFLLAAAELGLPLAGEALDPMSPLYLADLYSWMAIGAR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
TTESQIHRELASALDSAVGFKNSTDGSLDAALNAIVSASAPHAYLGMGKDGRVAVVNSRG
CHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCEEEEECCC
NPHCHLVLRGGGGRPNYDSVSIALAEQAMKKHDIPPAIMVDCAHANSWKQHTLQPRVLAD
CCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHCCCHHHHHH
AVSQIRHGNRSIRAFMLESFIEAGNQSIPADLSQLRYGCSVTDPCVDWHTTADILRDARA
HHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
KLRPLLES
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]