| Definition | Chromobacterium violaceum ATCC 12472 chromosome, complete genome. |
|---|---|
| Accession | NC_005085 |
| Length | 4,751,080 |
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The map label for this gene is entA [H]
Identifier: 34496937
GI number: 34496937
Start: 1579729
End: 1580493
Strand: Reverse
Name: entA [H]
Synonym: CV_1482
Alternate gene names: 34496937
Gene position: 1580493-1579729 (Counterclockwise)
Preceding gene: 34496938
Following gene: 34496936
Centisome position: 33.27
GC content: 73.07
Gene sequence:
>765_bases ATGGTCGGACTGGATTTCACCGGCCAATGCGTGTGGGTGACCGGCGCGGCCCAGGGCATAGGCCAGGAAGTGGCGCGCCG CTTCGTCGAGGCCGGCGCCCGGGTGATCGCGCTGGATCTGAAATTCAACAGCCCGGCCGCCCGCGGCGGCGTGCTGCGCG AGCTGCCGCTGGACATCCGCGACGCCGACGCCGTGGCCGCGCTGTGCCGCCGGCTGGCCGAGGAGGACGCGCTGCCCGAC GTGCTGGTCAACGCCGCCGGCGTGCTGCGCCTGGGCGCGTTCGACGCGCTGTCGATCGACGACTGGCAGCAATGCCTGGC CGTCAACGTCAGCGGCCCGTTCTACTTGCTGCGCGCGCTGATGCCGCACTTCAAGGCGCGCCGCGCCGGGGCCATCGTCA ACGTCGCCTCCAACGCCGCCCACGTGCCGCGCATCGACATGGCCGCCTACGGCGCGTCCAAGGCGGCGATGGCCAGCCTC AGCCACAACGCCGCGCTGGAGCTGGCGCCGTACGGCGTGCGCTGCAACGTGGTGTCTCCCGGCTCCACCGACACGCCGAT GCTGCGCGGCATGTGGCAGGACGAGCACGGCGCCGCCCGCACCATCGCCGGCAAGCCGGAAGCGTTCCGCCTGGGCATCC CGCTGGGCAAGCTGGCCACCCCGGCCGACGTCGCCGGCGCGGTGCTGTACCTGGCTTCCGACCTGGCCGGCCACGTCACG ATGCAGGACATCGTGGTGGACGGCGGCGCCACCCTGGCCGCCTGA
Upstream 100 bases:
>100_bases AGCTGGGCCTGGAAATCGGCTTCGAAGATTTGGCCCAAGACCTGACGCTGGACGGCTGGTGGACCGCCATCCAGGCCAAG CTGCCGCAGGAGGCCTGATC
Downstream 100 bases:
>100_bases ACATGCGGCCGCCGCGATGGGAAGAAGGCCTGCGCGCCGGCGGCGCGCGGCCGCCCTGTCGCCGACATCGGGGCCAGGCC TTGACGCCGGCCCTGCCGCA
Product: 2,3-dihydroxybenzoate-2,3-dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 254; Mature: 254
Protein sequence:
>254_residues MVGLDFTGQCVWVTGAAQGIGQEVARRFVEAGARVIALDLKFNSPAARGGVLRELPLDIRDADAVAALCRRLAEEDALPD VLVNAAGVLRLGAFDALSIDDWQQCLAVNVSGPFYLLRALMPHFKARRAGAIVNVASNAAHVPRIDMAAYGASKAAMASL SHNAALELAPYGVRCNVVSPGSTDTPMLRGMWQDEHGAARTIAGKPEAFRLGIPLGKLATPADVAGAVLYLASDLAGHVT MQDIVVDGGATLAA
Sequences:
>Translated_254_residues MVGLDFTGQCVWVTGAAQGIGQEVARRFVEAGARVIALDLKFNSPAARGGVLRELPLDIRDADAVAALCRRLAEEDALPD VLVNAAGVLRLGAFDALSIDDWQQCLAVNVSGPFYLLRALMPHFKARRAGAIVNVASNAAHVPRIDMAAYGASKAAMASL SHNAALELAPYGVRCNVVSPGSTDTPMLRGMWQDEHGAARTIAGKPEAFRLGIPLGKLATPADVAGAVLYLASDLAGHVT MQDIVVDGGATLAA >Mature_254_residues MVGLDFTGQCVWVTGAAQGIGQEVARRFVEAGARVIALDLKFNSPAARGGVLRELPLDIRDADAVAALCRRLAEEDALPD VLVNAAGVLRLGAFDALSIDDWQQCLAVNVSGPFYLLRALMPHFKARRAGAIVNVASNAAHVPRIDMAAYGASKAAMASL SHNAALELAPYGVRCNVVSPGSTDTPMLRGMWQDEHGAARTIAGKPEAFRLGIPLGKLATPADVAGAVLYLASDLAGHVT MQDIVVDGGATLAA
Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=32.4110671936759, Blast_Score=105, Evalue=4e-23, Organism=Homo sapiens, GI66933014, Length=233, Percent_Identity=30.9012875536481, Blast_Score=105, Evalue=5e-23, Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=29.3172690763052, Blast_Score=100, Evalue=9e-22, Organism=Homo sapiens, GI7705925, Length=256, Percent_Identity=30.46875, Blast_Score=94, Evalue=9e-20, Organism=Homo sapiens, GI19923817, Length=263, Percent_Identity=27.3764258555133, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=30.4347826086957, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI10190704, Length=257, Percent_Identity=28.7937743190661, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=30.8943089430894, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI4503817, Length=239, Percent_Identity=28.4518828451883, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI59889578, Length=234, Percent_Identity=28.6324786324786, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI33667109, Length=181, Percent_Identity=34.2541436464088, Blast_Score=81, Evalue=7e-16, Organism=Homo sapiens, GI119392083, Length=209, Percent_Identity=32.0574162679426, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI126723750, Length=256, Percent_Identity=25.390625, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI4504505, Length=198, Percent_Identity=29.7979797979798, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI7706318, Length=190, Percent_Identity=29.4736842105263, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI20149619, Length=197, Percent_Identity=27.9187817258883, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4758504, Length=203, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI4504503, Length=185, Percent_Identity=31.8918918918919, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI31542939, Length=208, Percent_Identity=27.8846153846154, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI223718074, Length=191, Percent_Identity=32.4607329842932, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI142976729, Length=194, Percent_Identity=26.2886597938144, Blast_Score=68, Evalue=9e-12, Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=54.296875, Blast_Score=269, Evalue=1e-73, Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=34.8837209302326, Blast_Score=132, Evalue=3e-32, Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=29.9212598425197, Blast_Score=115, Evalue=4e-27, Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=28.1746031746032, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI1790717, Length=257, Percent_Identity=26.4591439688716, Blast_Score=100, Evalue=8e-23, Organism=Escherichia coli, GI1788459, Length=255, Percent_Identity=30.9803921568627, Blast_Score=93, Evalue=1e-20, Organism=Escherichia coli, GI1787905, Length=255, Percent_Identity=30.5882352941176, Blast_Score=88, Evalue=4e-19, Organism=Escherichia coli, GI1787820, Length=250, Percent_Identity=30.4, Blast_Score=88, Evalue=7e-19, Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=30.2788844621514, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI2367365, Length=252, Percent_Identity=29.3650793650794, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI87082160, Length=259, Percent_Identity=24.3243243243243, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=26.5873015873016, Blast_Score=65, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=31.8548387096774, Blast_Score=112, Evalue=1e-25, Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=30.0395256916996, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=32.2709163346614, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=28.515625, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI71994600, Length=170, Percent_Identity=36.4705882352941, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=29.6296296296296, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17544670, Length=275, Percent_Identity=28.7272727272727, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=27.9850746268657, Blast_Score=91, Evalue=8e-19, Organism=Caenorhabditis elegans, GI17562910, Length=271, Percent_Identity=28.7822878228782, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI71994604, Length=170, Percent_Identity=35.2941176470588, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17508651, Length=255, Percent_Identity=30.1960784313725, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI193204405, Length=270, Percent_Identity=28.5185185185185, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=27.7153558052434, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=27.0588235294118, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17562908, Length=269, Percent_Identity=28.996282527881, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=28.0898876404494, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=28.1368821292776, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=28.5171102661597, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17531453, Length=272, Percent_Identity=28.3088235294118, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17560150, Length=269, Percent_Identity=27.5092936802974, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17562990, Length=272, Percent_Identity=28.3088235294118, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17538182, Length=228, Percent_Identity=31.5789473684211, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17559104, Length=270, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=27.2030651340996, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=26.2357414448669, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17536651, Length=258, Percent_Identity=27.1317829457364, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17568967, Length=192, Percent_Identity=27.0833333333333, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17564282, Length=194, Percent_Identity=25.2577319587629, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17565030, Length=269, Percent_Identity=26.7657992565056, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17567345, Length=191, Percent_Identity=25.130890052356, Blast_Score=65, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=26.8482490272374, Blast_Score=77, Evalue=2e-15, Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=29.1666666666667, Blast_Score=75, Evalue=1e-14, Organism=Saccharomyces cerevisiae, GI6323882, Length=245, Percent_Identity=26.1224489795918, Blast_Score=66, Evalue=5e-12, Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=32.6771653543307, Blast_Score=103, Evalue=8e-23, Organism=Drosophila melanogaster, GI24639444, Length=256, Percent_Identity=29.6875, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI24643142, Length=253, Percent_Identity=32.4110671936759, Blast_Score=98, Evalue=6e-21, Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=29.1828793774319, Blast_Score=97, Evalue=7e-21, Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=31.6205533596838, Blast_Score=94, Evalue=9e-20, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=30.1587301587302, Blast_Score=91, Evalue=6e-19, Organism=Drosophila melanogaster, GI24644337, Length=255, Percent_Identity=32.156862745098, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI17737361, Length=226, Percent_Identity=33.1858407079646, Blast_Score=84, Evalue=6e-17, Organism=Drosophila melanogaster, GI24644339, Length=257, Percent_Identity=31.5175097276265, Blast_Score=84, Evalue=8e-17, Organism=Drosophila melanogaster, GI281364892, Length=233, Percent_Identity=25.7510729613734, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI21356301, Length=234, Percent_Identity=30.7692307692308, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI116007236, Length=256, Percent_Identity=26.5625, Blast_Score=74, Evalue=6e-14, Organism=Drosophila melanogaster, GI18859837, Length=205, Percent_Identity=30.7317073170732, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI21358495, Length=197, Percent_Identity=28.4263959390863, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI116007238, Length=185, Percent_Identity=28.1081081081081, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR003560 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.3.1.28 [H]
Molecular weight: Translated: 26450; Mature: 26450
Theoretical pI: Translated: 6.35; Mature: 6.35
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 4.3 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 4.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVGLDFTGQCVWVTGAAQGIGQEVARRFVEAGARVIALDLKFNSPAARGGVLRELPLDIR CCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCHHHCCCCCC DADAVAALCRRLAEEDALPDVLVNAAGVLRLGAFDALSIDDWQQCLAVNVSGPFYLLRAL CHHHHHHHHHHHHHHCCCHHHHHHHHHHEEECCCCCCCHHHHHHHEEECCCCHHHHHHHH MPHFKARRAGAIVNVASNAAHVPRIDMAAYGASKAAMASLSHNAALELAPYGVRCNVVSP HHHHHHHHCCEEEEECCCCCCCCCCHHHHHCCCHHHHHHHCCCCEEEEECCCEEEEEECC GSTDTPMLRGMWQDEHGAARTIAGKPEAFRLGIPLGKLATPADVAGAVLYLASDLAGHVT CCCCCHHHHCCCCCCCCCEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCEE MQDIVVDGGATLAA EEEEEEECCCCCCC >Mature Secondary Structure MVGLDFTGQCVWVTGAAQGIGQEVARRFVEAGARVIALDLKFNSPAARGGVLRELPLDIR CCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCHHHCCCCCC DADAVAALCRRLAEEDALPDVLVNAAGVLRLGAFDALSIDDWQQCLAVNVSGPFYLLRAL CHHHHHHHHHHHHHHCCCHHHHHHHHHHEEECCCCCCCHHHHHHHEEECCCCHHHHHHHH MPHFKARRAGAIVNVASNAAHVPRIDMAAYGASKAAMASLSHNAALELAPYGVRCNVVSP HHHHHHHHCCEEEEECCCCCCCCCCHHHHHCCCHHHHHHHCCCCEEEEECCCEEEEEECC GSTDTPMLRGMWQDEHGAARTIAGKPEAFRLGIPLGKLATPADVAGAVLYLASDLAGHVT CCCCCHHHHCCCCCCCCCEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCEE MQDIVVDGGATLAA EEEEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2521622; 2521621; 9278503 [H]