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The map label for this gene is creB [H]

Identifier: 34496836

GI number: 34496836

Start: 1457356

End: 1457994

Strand: Direct

Name: creB [H]

Synonym: CV_1381

Alternate gene names: 34496836

Gene position: 1457356-1457994 (Clockwise)

Preceding gene: 34496835

Following gene: 34496837

Centisome position: 30.67

GC content: 71.36

Gene sequence:

>639_bases
TTGCTGATTGAAGACGACGCCGAACTGGGCGCGGGCCTGCGCCAATTCCTGCAGCAGCAGGGCTACGACTGCCTGTGGCT
GCGCGACGGCGGCGAAGTGGCCGCCCACTGGCGGCAGGCCGAGCTGGCGATCCTGGACCGCCAGCTGCCGGACGGCGATT
CGCTGCGCCTGTTGCCGCAGTGGCTGGCGCTGAAGGCGCTGCCGGTGATCGTGCTTACCGCCCGGGTGGAGCTCGATGAC
CGGGTGGCCGGGCTGGAGGCCGGCGCGCGCGACTACCTGACCAAGCCCTTCGCCCATGTCGAGCTGCTGGCCCGCGTGCG
CGCCCAATTGCGACCGCTGGGCGAGGGCGCCTTGGCCTGCGGCGAGCTGCAGTTGTTTCCGGCCAGGCAGGCTGCGGCCT
GGCGCGGCGGCGAGGTGGCGCTCACCCGCACCGAGTTCGACCTGCTGGCGATGCTGGCGCGGATGCCGGGCCGGGTGTTC
ACCCGCGACGAGCTGCTGAACCAGGTATGGGGCTACCAGCATTTCCCGTCCACCCGCACCGTGGACACCCATGTGCTGCA
GCTGCGGCAGAAGCTGCCCGACATCCCGATAGAAACCGTGCGCGGCGTCGGCTACCGGCTGAGCGGGGGCGGGGCGTGA

Upstream 100 bases:

>100_bases
GGCCTGGCCATCGTGCGGCGGGTGATGGCCAGGCTGGGCGGCCGGCTGACGCTGGAAGGGCCGCCGACCACATTCGCGCT
GGAGTTGCCGTGTGACGATA

Downstream 100 bases:

>100_bases
GGCCGCCATTCTGGCTGGCCCTGGCCTGGGCGGCGCAGGCGGCCGCCGCGCCGCTGCTTCCGGCCACGCCGCTGGAGCCG
GCCTATCACGCCTTGCTTTC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MLIEDDAELGAGLRQFLQQQGYDCLWLRDGGEVAAHWRQAELAILDRQLPDGDSLRLLPQWLALKALPVIVLTARVELDD
RVAGLEAGARDYLTKPFAHVELLARVRAQLRPLGEGALACGELQLFPARQAAAWRGGEVALTRTEFDLLAMLARMPGRVF
TRDELLNQVWGYQHFPSTRTVDTHVLQLRQKLPDIPIETVRGVGYRLSGGGA

Sequences:

>Translated_212_residues
MLIEDDAELGAGLRQFLQQQGYDCLWLRDGGEVAAHWRQAELAILDRQLPDGDSLRLLPQWLALKALPVIVLTARVELDD
RVAGLEAGARDYLTKPFAHVELLARVRAQLRPLGEGALACGELQLFPARQAAAWRGGEVALTRTEFDLLAMLARMPGRVF
TRDELLNQVWGYQHFPSTRTVDTHVLQLRQKLPDIPIETVRGVGYRLSGGGA
>Mature_212_residues
MLIEDDAELGAGLRQFLQQQGYDCLWLRDGGEVAAHWRQAELAILDRQLPDGDSLRLLPQWLALKALPVIVLTARVELDD
RVAGLEAGARDYLTKPFAHVELLARVRAQLRPLGEGALACGELQLFPARQAAAWRGGEVALTRTEFDLLAMLARMPGRVF
TRDELLNQVWGYQHFPSTRTVDTHVLQLRQKLPDIPIETVRGVGYRLSGGGA

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=41.1764705882353, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1790552, Length=214, Percent_Identity=40.6542056074766, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1788394, Length=218, Percent_Identity=36.2385321100917, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI87082012, Length=215, Percent_Identity=38.1395348837209, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=34.841628959276, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI2367329, Length=222, Percent_Identity=36.4864864864865, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1789402, Length=213, Percent_Identity=36.150234741784, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=36.1990950226244, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=35.6164383561644, Blast_Score=104, Evalue=3e-24,
Organism=Escherichia coli, GI1787375, Length=215, Percent_Identity=32.093023255814, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=30, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=28.9473684210526, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1787229, Length=223, Percent_Identity=29.5964125560538, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI145693140, Length=227, Percent_Identity=27.7533039647577, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 23584; Mature: 23584

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIEDDAELGAGLRQFLQQQGYDCLWLRDGGEVAAHWRQAELAILDRQLPDGDSLRLLPQ
CCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
WLALKALPVIVLTARVELDDRVAGLEAGARDYLTKPFAHVELLARVRAQLRPLGEGALAC
HHHHHHHHHHEEEEEECCCHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEE
GELQLFPARQAAAWRGGEVALTRTEFDLLAMLARMPGRVFTRDELLNQVWGYQHFPSTRT
CCEEECCCHHHHCCCCCCEEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCC
VDTHVLQLRQKLPDIPIETVRGVGYRLSGGGA
HHHHHHHHHHHCCCCCHHHHCCCCEEECCCCC
>Mature Secondary Structure
MLIEDDAELGAGLRQFLQQQGYDCLWLRDGGEVAAHWRQAELAILDRQLPDGDSLRLLPQ
CCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
WLALKALPVIVLTARVELDDRVAGLEAGARDYLTKPFAHVELLARVRAQLRPLGEGALAC
HHHHHHHHHHEEEEEECCCHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEE
GELQLFPARQAAAWRGGEVALTRTEFDLLAMLARMPGRVFTRDELLNQVWGYQHFPSTRT
CCEEECCCHHHHCCCCCCEEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCC
VDTHVLQLRQKLPDIPIETVRGVGYRLSGGGA
HHHHHHHHHHHCCCCCHHHHCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]