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The map label for this gene is yngF [H]

Identifier: 34496785

GI number: 34496785

Start: 1400534

End: 1401322

Strand: Reverse

Name: yngF [H]

Synonym: CV_1330

Alternate gene names: 34496785

Gene position: 1401322-1400534 (Counterclockwise)

Preceding gene: 34496786

Following gene: 34496784

Centisome position: 29.49

GC content: 66.16

Gene sequence:

>789_bases
ATGAGCACCGACGCCGTAACGCTGAGCGTGGACAACCGTGGCATCGCCACCGTCGCGCTGAACCGCCCGGGCCTGCACAA
TGCGCTGGACGACGAAACCATCAGCCTCTTGGCCGCCACGCTGGAAACGCTGGCGGAAGACGCCACGGTGCGCATGGTGG
TATTGACCGGCAGCGGCATCAGCTTCTCCGCCGGCCATGATCCGGAGTGGCTGCGCCGGCTGGCGGAATTCTCCGCCAAC
GAGCTGAACCGCTACGCGCAACAGATCGCGCGGCTGCTGCATACGCTGGACACGCTGCCCAAGCCGACGCTGGCCAAGGT
CCAGGGCTCGGCCTTCGGCCTGGGCGTGGCCATGGTCGCCTGTTGCGACATCACCATCAGCGCGTCCGAAGCGCTGTACA
GCCTCGCCGACGTCAGGTTCGGCCAGATTCCCGCGCTCACCGCCCCCTACCTGATCCGCGCGATAGGCGAACGCGCCACC
CGGCGCTACAGCATCACCGCCGAGCGCTTCAACGCCGGCAAGGCCAAGCGGCTGGGCCTGATCCATCAGGTGGTGGAAAA
CGACGAGCTGAACGCCGCGGTGGAGCATATGGTGGGCCAACTGCTGCTGAACAGCCCGGCGGCGATGCGCGCCACCAAGC
ATCTGATAGGCGAGATCGGCAAGCAGGAGATCACGCCCCAGGTGATGCAGCGCTGCATCGAACACAGCCTGACGGTGCGA
ATGAGCGACGAAGGGCGCGAAGGCATGCGCGCGCTGATCGAGATGCGCAAGCCGGGCTGGATGGAATAA

Upstream 100 bases:

>100_bases
GTGCTGCACATCGAAGCCGTGGAAGCCTTCGCCCGCGCCATCGTCCGCTTCCGCCAGGACTGAGGCGGCCAACCATTCTT
TCAAGACAGGGGGAAACATG

Downstream 100 bases:

>100_bases
GAGCCGCTCACAAAACCTCGTAGCGCATCTGAGCCAAGGCGCGCCGACGCAGACAGTACGCACAGTACGGCAAGGAGGCG
CAACGCAGGATCAGGGGTGT

Product: enoyl-CoA hydratase protein

Products: 1,4-dihydroxy-2-naphthoate; CoA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MSTDAVTLSVDNRGIATVALNRPGLHNALDDETISLLAATLETLAEDATVRMVVLTGSGISFSAGHDPEWLRRLAEFSAN
ELNRYAQQIARLLHTLDTLPKPTLAKVQGSAFGLGVAMVACCDITISASEALYSLADVRFGQIPALTAPYLIRAIGERAT
RRYSITAERFNAGKAKRLGLIHQVVENDELNAAVEHMVGQLLLNSPAAMRATKHLIGEIGKQEITPQVMQRCIEHSLTVR
MSDEGREGMRALIEMRKPGWME

Sequences:

>Translated_262_residues
MSTDAVTLSVDNRGIATVALNRPGLHNALDDETISLLAATLETLAEDATVRMVVLTGSGISFSAGHDPEWLRRLAEFSAN
ELNRYAQQIARLLHTLDTLPKPTLAKVQGSAFGLGVAMVACCDITISASEALYSLADVRFGQIPALTAPYLIRAIGERAT
RRYSITAERFNAGKAKRLGLIHQVVENDELNAAVEHMVGQLLLNSPAAMRATKHLIGEIGKQEITPQVMQRCIEHSLTVR
MSDEGREGMRALIEMRKPGWME
>Mature_261_residues
STDAVTLSVDNRGIATVALNRPGLHNALDDETISLLAATLETLAEDATVRMVVLTGSGISFSAGHDPEWLRRLAEFSANE
LNRYAQQIARLLHTLDTLPKPTLAKVQGSAFGLGVAMVACCDITISASEALYSLADVRFGQIPALTAPYLIRAIGERATR
RYSITAERFNAGKAKRLGLIHQVVENDELNAAVEHMVGQLLLNSPAAMRATKHLIGEIGKQEITPQVMQRCIEHSLTVRM
SDEGREGMRALIEMRKPGWME

Specific function: Converts O-Succinylbenzoyl-CoA (Osb-CoA) To 1,4- Dihydroxy-2-Naphthoic Acid (Dhna). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=253, Percent_Identity=27.6679841897233, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI4502327, Length=258, Percent_Identity=29.4573643410853, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI31542718, Length=254, Percent_Identity=25.5905511811024, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI70995211, Length=213, Percent_Identity=26.7605633802817, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI221136756, Length=193, Percent_Identity=24.3523316062176, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI221136753, Length=193, Percent_Identity=24.3523316062176, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI221307494, Length=193, Percent_Identity=24.3523316062176, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1788597, Length=252, Percent_Identity=26.1904761904762, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787659, Length=246, Percent_Identity=28.4552845528455, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI221142681, Length=254, Percent_Identity=27.5590551181102, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787660, Length=253, Percent_Identity=28.0632411067194, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87082183, Length=266, Percent_Identity=26.6917293233083, Blast_Score=75, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25145438, Length=248, Percent_Identity=27.4193548387097, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17554946, Length=255, Percent_Identity=27.4509803921569, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17540714, Length=229, Percent_Identity=26.2008733624454, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17536985, Length=218, Percent_Identity=24.7706422018349, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17534483, Length=219, Percent_Identity=26.027397260274, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17540306, Length=164, Percent_Identity=26.219512195122, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17535521, Length=230, Percent_Identity=25.6521739130435, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24653139, Length=255, Percent_Identity=29.4117647058824, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI20129971, Length=185, Percent_Identity=29.1891891891892, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24653477, Length=185, Percent_Identity=29.1891891891892, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI19922422, Length=258, Percent_Identity=21.7054263565891, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: 4.1.3.36; 4.2.1.17

Molecular weight: Translated: 28558; Mature: 28427

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTDAVTLSVDNRGIATVALNRPGLHNALDDETISLLAATLETLAEDATVRMVVLTGSGI
CCCCEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCE
SFSAGHDPEWLRRLAEFSANELNRYAQQIARLLHTLDTLPKPTLAKVQGSAFGLGVAMVA
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHH
CCDITISASEALYSLADVRFGQIPALTAPYLIRAIGERATRRYSITAERFNAGKAKRLGL
HHCCEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHEEEEEHHHHCCCHHHHHHH
IHQVVENDELNAAVEHMVGQLLLNSPAAMRATKHLIGEIGKQEITPQVMQRCIEHSLTVR
HHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHCCCHHHHHHHHHHHEEEE
MSDEGREGMRALIEMRKPGWME
ECCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
STDAVTLSVDNRGIATVALNRPGLHNALDDETISLLAATLETLAEDATVRMVVLTGSGI
CCCEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCE
SFSAGHDPEWLRRLAEFSANELNRYAQQIARLLHTLDTLPKPTLAKVQGSAFGLGVAMVA
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHH
CCDITISASEALYSLADVRFGQIPALTAPYLIRAIGERATRRYSITAERFNAGKAKRLGL
HHCCEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHEEEEEHHHHCCCHHHHHHH
IHQVVENDELNAAVEHMVGQLLLNSPAAMRATKHLIGEIGKQEITPQVMQRCIEHSLTVR
HHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHCCCHHHHHHHHHHHEEEE
MSDEGREGMRALIEMRKPGWME
ECCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: o-succinylbenzoyl-CoA

Specific reaction: o-succinylbenzoyl-CoA = 1,4-dihydroxy-2-naphthoate + CoA

General reaction: Carbon-Carbon Lyases; Oxo-Acid-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]