Click here to switch to the map view.

The map label for this gene is ampC [H]

Identifier: 34496765

GI number: 34496765

Start: 1380729

End: 1381919

Strand: Direct

Name: ampC [H]

Synonym: CV_1310

Alternate gene names: 34496765

Gene position: 1380729-1381919 (Clockwise)

Preceding gene: 34496764

Following gene: 34496766

Centisome position: 29.06

GC content: 65.16

Gene sequence:

>1191_bases
ATGATGCAATCCCTGAAGTTTCGAACCTTGGCGGGCATGCTTGGCTGCCTGACCTTTCTTCCGCTCGCGGCCCAGGCCGC
CAATGATGCCGGCAAGTCCGATCTCGATGCGGCGGTCGAGGCGACGATCCCGCCGCTGATGAAGGCCAAGGACATTCCCG
GCATGGCGGTGGCGGTGCTGGCCGACGGCAAGGCGCATTACTTCAATTACGGCGTCGCTTCCCGGGAGACCGGCCAGCCG
GTGACGCAGGATACCTTGTTCGAACTGGGGTCGATCAGCAAAACCTTCACCGGCATCCTGGGCGGCTACGCGCTGGCGCA
GGGCAAGCTGTCGCTGGCCGACAAGGCCAGCCGCTACCAGCCGGAGCTCAAGGGCAGCGTCTTCGACCGCGTCTCGCTGC
TGCAACTGGCCACCTACAGCGCCGGCGGCCTGCCGTTGCAGTTTCCGGACGCGGTTGCCGGCCAAGCCTCGATGCTGGCC
TATTACCGCGGCTGGAAGCCGGATTACGCGCCAGGCGAGCGGCGCTTGTACTCGAATCCCAGCATCGGCCTGTTCGGACA
CCTGGCGGCGCGCAGCCTGGGCCAGCCATTCGACCAGGCGATGGAACGGGGGCTGTTGCCGAAGCTGGGCCTGAGCCACA
CCTTCATTCATGTGCCGGAAGCTGAGCAGTCCCGTTATGCCTGGGGTTATGCCAAGGCAGGCAAGCCGATCCGGGTGGGG
GCTGGCGTTCTGGACGCCGAAGCCTACGGCATCAAGTCCAGCGCGGCGGATCTGCTGAAATACCTGGCGATTAATATGTC
GCCTCCCGCGGATCCCGCCCTGCAGAGGGCGCTCGACGCCAGCCACGCCGCTTATTACCGCGTAGGCGACATGCGCCAGG
GGTTGGGCTGGGAGGGGTATCGCTATCCGATCAGCCTGGAGCGCTTGCTGGCCGGGAATTCCAACGAGATCGCGTTTCAG
CCGCAGAAGGTTGAGTGGCTGAATCCGCCGCGTCTGGCCGAGGGCGATGTCCTGCTGAACAAGACCGGCTCCACCAGCGG
TTTCGGCGCCTATGTGCTGTTCGTGCCAGCGCGCAAGGTGGGCATCGTGATGCTGGCCAACCGCAATTACCCGAATGCCG
AGCGGGTCCGCGCGGCATACCGGATATTGTCGGCGGTGGATCCGTCGCTGGTGCGCAGGCGCGGCGATTGA

Upstream 100 bases:

>100_bases
CGGCGGCGGTTTGTAACTTGGCGGGGCTTTCCCAATCGGGACCTGGCGCCGCGCGGAAGAGCCGCGCAGGCCGCGATGTC
CCCCGCACCGGAGTTCCGCG

Downstream 100 bases:

>100_bases
TGCGGCGCGGGGCCCGGGCGGGACCTCGTCCGGGACTGCGCGATTTTGGCTGGCCTTTGGAACAGGTTTTGCGCTGCTTG
ATGCGCTTATAATTTTTTTC

Product: beta-lactamase

Products: NA

Alternate protein names: Cephalosporinase [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MMQSLKFRTLAGMLGCLTFLPLAAQAANDAGKSDLDAAVEATIPPLMKAKDIPGMAVAVLADGKAHYFNYGVASRETGQP
VTQDTLFELGSISKTFTGILGGYALAQGKLSLADKASRYQPELKGSVFDRVSLLQLATYSAGGLPLQFPDAVAGQASMLA
YYRGWKPDYAPGERRLYSNPSIGLFGHLAARSLGQPFDQAMERGLLPKLGLSHTFIHVPEAEQSRYAWGYAKAGKPIRVG
AGVLDAEAYGIKSSAADLLKYLAINMSPPADPALQRALDASHAAYYRVGDMRQGLGWEGYRYPISLERLLAGNSNEIAFQ
PQKVEWLNPPRLAEGDVLLNKTGSTSGFGAYVLFVPARKVGIVMLANRNYPNAERVRAAYRILSAVDPSLVRRRGD

Sequences:

>Translated_396_residues
MMQSLKFRTLAGMLGCLTFLPLAAQAANDAGKSDLDAAVEATIPPLMKAKDIPGMAVAVLADGKAHYFNYGVASRETGQP
VTQDTLFELGSISKTFTGILGGYALAQGKLSLADKASRYQPELKGSVFDRVSLLQLATYSAGGLPLQFPDAVAGQASMLA
YYRGWKPDYAPGERRLYSNPSIGLFGHLAARSLGQPFDQAMERGLLPKLGLSHTFIHVPEAEQSRYAWGYAKAGKPIRVG
AGVLDAEAYGIKSSAADLLKYLAINMSPPADPALQRALDASHAAYYRVGDMRQGLGWEGYRYPISLERLLAGNSNEIAFQ
PQKVEWLNPPRLAEGDVLLNKTGSTSGFGAYVLFVPARKVGIVMLANRNYPNAERVRAAYRILSAVDPSLVRRRGD
>Mature_396_residues
MMQSLKFRTLAGMLGCLTFLPLAAQAANDAGKSDLDAAVEATIPPLMKAKDIPGMAVAVLADGKAHYFNYGVASRETGQP
VTQDTLFELGSISKTFTGILGGYALAQGKLSLADKASRYQPELKGSVFDRVSLLQLATYSAGGLPLQFPDAVAGQASMLA
YYRGWKPDYAPGERRLYSNPSIGLFGHLAARSLGQPFDQAMERGLLPKLGLSHTFIHVPEAEQSRYAWGYAKAGKPIRVG
AGVLDAEAYGIKSSAADLLKYLAINMSPPADPALQRALDASHAAYYRVGDMRQGLGWEGYRYPISLERLLAGNSNEIAFQ
PQKVEWLNPPRLAEGDVLLNKTGSTSGFGAYVLFVPARKVGIVMLANRNYPNAERVRAAYRILSAVDPSLVRRRGD

Specific function: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-C beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI1790593, Length=373, Percent_Identity=46.3806970509383, Blast_Score=356, Evalue=2e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001586
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 42705; Mature: 42705

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS00336 BETA_LACTAMASE_C

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQSLKFRTLAGMLGCLTFLPLAAQAANDAGKSDLDAAVEATIPPLMKAKDIPGMAVAVL
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHCCCCCCEEEEEE
ADGKAHYFNYGVASRETGQPVTQDTLFELGSISKTFTGILGGYALAQGKLSLADKASRYQ
ECCCEEEEECCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
PELKGSVFDRVSLLQLATYSAGGLPLQFPDAVAGQASMLAYYRGWKPDYAPGERRLYSNP
CHHCHHHHHHHHHHHHHHCCCCCCCEECCCHHCCHHHHHHHHCCCCCCCCCCCCEEECCC
SIGLFGHLAARSLGQPFDQAMERGLLPKLGLSHTFIHVPEAEQSRYAWGYAKAGKPIRVG
CCCHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEECCCCCCCCEEEEECCCCCCEEEC
AGVLDAEAYGIKSSAADLLKYLAINMSPPADPALQRALDASHAAYYRVGDMRQGLGWEGY
CCEECCHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEECCHHCCCCCCCE
RYPISLERLLAGNSNEIAFQPQKVEWLNPPRLAEGDVLLNKTGSTSGFGAYVLFVPARKV
ECCEEHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEEECCCE
GIVMLANRNYPNAERVRAAYRILSAVDPSLVRRRGD
EEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHCCC
>Mature Secondary Structure
MMQSLKFRTLAGMLGCLTFLPLAAQAANDAGKSDLDAAVEATIPPLMKAKDIPGMAVAVL
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHCCCCCCEEEEEE
ADGKAHYFNYGVASRETGQPVTQDTLFELGSISKTFTGILGGYALAQGKLSLADKASRYQ
ECCCEEEEECCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
PELKGSVFDRVSLLQLATYSAGGLPLQFPDAVAGQASMLAYYRGWKPDYAPGERRLYSNP
CHHCHHHHHHHHHHHHHHCCCCCCCEECCCHHCCHHHHHHHHCCCCCCCCCCCCEEECCC
SIGLFGHLAARSLGQPFDQAMERGLLPKLGLSHTFIHVPEAEQSRYAWGYAKAGKPIRVG
CCCHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEECCCCCCCCEEEEECCCCCCEEEC
AGVLDAEAYGIKSSAADLLKYLAINMSPPADPALQRALDASHAAYYRVGDMRQGLGWEGY
CCEECCHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEECCHHCCCCCCCE
RYPISLERLLAGNSNEIAFQPQKVEWLNPPRLAEGDVLLNKTGSTSGFGAYVLFVPARKV
ECCEEHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEEECCCE
GIVMLANRNYPNAERVRAAYRILSAVDPSLVRRRGD
EEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA