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The map label for this gene is glnP [H]

Identifier: 34496728

GI number: 34496728

Start: 1339410

End: 1340093

Strand: Reverse

Name: glnP [H]

Synonym: CV_1273

Alternate gene names: 34496728

Gene position: 1340093-1339410 (Counterclockwise)

Preceding gene: 34496729

Following gene: 34496726

Centisome position: 28.21

GC content: 68.71

Gene sequence:

>684_bases
ATGATGCCTGCGGTGATACAGGACAACCTCGACTACCTGCTGTGGGGCAATCTGGCCGGCGGCGAGCCCGGCGGCCTGCT
GCTGACGCTGCTGCTGAGCCTGGCCGCGGCGCTGCTGGCTAGCCTTCTGGGGCTGGCGCTGGGCATCGCCCAGCTGATGG
GCGGCGCGGCGCTCAGGCGCATGCTGACGGCCATCACCGCGGTGCTGCGCGCGATCCCGGTGCTGATGCTGATCTTCTGG
TGCTATTTCCTGCTGCCGCTGCTGTTCGGCGTCGACATCCCCGGCCTGCTGACGGTGATCCTGGCGCTGGCGCTGATCCA
CTCCGCCTATCTGGGCCAGGCGGTGCTGGCCGGCCTGACGGCCGTCGGCCGCGGCCAGTGGCACGCCGGGCTGGCGCTAG
GCTTCTCGCGCTGGCAGACGCTGCGCTGGCTGATTCTGCCGCAGGCGCTGCGCATCATGCTGCCCTCCTTCATCAACCAG
TGGGTGTCGCTGCTGAAGGACAGCTCGCTGGCCTACATCGTCGGCGTCGCCGAGTTCACCTTCGTCGCCACCCAGGTCAA
CAACCGCGAGCAGGTGTATCCGCTGGAAATCTTCAGCGCCATCGCCATCGGCTACCTGCTGCTGTGCGGCCTGCTGCAGC
TGGCCGGCCATCTGGCGGAACGCCGCTGGCGGCGGACAGCCTGA

Upstream 100 bases:

>100_bases
CCTTCCAGTCCTTCGCCGCCGCCACCGCGCTCTACCTGGCGCTGGTGCTGATCACCCAATTGCTGGCCCAGCGGCCGGAG
CCGGCCTGGAGGACGATGCG

Downstream 100 bases:

>100_bases
TCACAGTTCGCGGCCGCCGCTGGCGATCGCCCGCTGGTACCAGAAGAAGCTGTCCTTGCGCACGCGGCGCAGATCGCGGG
CGTCGGTCTCATCGCGGTTG

Product: glutamine transport system permease

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MMPAVIQDNLDYLLWGNLAGGEPGGLLLTLLLSLAAALLASLLGLALGIAQLMGGAALRRMLTAITAVLRAIPVLMLIFW
CYFLLPLLFGVDIPGLLTVILALALIHSAYLGQAVLAGLTAVGRGQWHAGLALGFSRWQTLRWLILPQALRIMLPSFINQ
WVSLLKDSSLAYIVGVAEFTFVATQVNNREQVYPLEIFSAIAIGYLLLCGLLQLAGHLAERRWRRTA

Sequences:

>Translated_227_residues
MMPAVIQDNLDYLLWGNLAGGEPGGLLLTLLLSLAAALLASLLGLALGIAQLMGGAALRRMLTAITAVLRAIPVLMLIFW
CYFLLPLLFGVDIPGLLTVILALALIHSAYLGQAVLAGLTAVGRGQWHAGLALGFSRWQTLRWLILPQALRIMLPSFINQ
WVSLLKDSSLAYIVGVAEFTFVATQVNNREQVYPLEIFSAIAIGYLLLCGLLQLAGHLAERRWRRTA
>Mature_227_residues
MMPAVIQDNLDYLLWGNLAGGEPGGLLLTLLLSLAAALLASLLGLALGIAQLMGGAALRRMLTAITAVLRAIPVLMLIFW
CYFLLPLLFGVDIPGLLTVILALALIHSAYLGQAVLAGLTAVGRGQWHAGLALGFSRWQTLRWLILPQALRIMLPSFINQ
WVSLLKDSSLAYIVGVAEFTFVATQVNNREQVYPLEIFSAIAIGYLLLCGLLQLAGHLAERRWRRTA

Specific function: Part of the ABC transporter complex tcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787030, Length=187, Percent_Identity=34.2245989304813, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1786873, Length=187, Percent_Identity=31.5508021390374, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788226, Length=192, Percent_Identity=32.2916666666667, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1786874, Length=213, Percent_Identity=26.7605633802817, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI87082239, Length=208, Percent_Identity=30.7692307692308, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1788645, Length=231, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787087, Length=174, Percent_Identity=29.8850574712644, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI48994930, Length=132, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788646, Length=209, Percent_Identity=25.3588516746411, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787086, Length=209, Percent_Identity=30.1435406698565, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24628; Mature: 24628

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPAVIQDNLDYLLWGNLAGGEPGGLLLTLLLSLAAALLASLLGLALGIAQLMGGAALRR
CCCCHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLTAITAVLRAIPVLMLIFWCYFLLPLLFGVDIPGLLTVILALALIHSAYLGQAVLAGLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGRGQWHAGLALGFSRWQTLRWLILPQALRIMLPSFINQWVSLLKDSSLAYIVGVAEFT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FVATQVNNREQVYPLEIFSAIAIGYLLLCGLLQLAGHLAERRWRRTA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMPAVIQDNLDYLLWGNLAGGEPGGLLLTLLLSLAAALLASLLGLALGIAQLMGGAALRR
CCCCHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLTAITAVLRAIPVLMLIFWCYFLLPLLFGVDIPGLLTVILALALIHSAYLGQAVLAGLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGRGQWHAGLALGFSRWQTLRWLILPQALRIMLPSFINQWVSLLKDSSLAYIVGVAEFT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FVATQVNNREQVYPLEIFSAIAIGYLLLCGLLQLAGHLAERRWRRTA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 8969502; 9384377 [H]