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The map label for this gene is acoR [H]

Identifier: 34495847

GI number: 34495847

Start: 406608

End: 408392

Strand: Reverse

Name: acoR [H]

Synonym: CV_0392

Alternate gene names: 34495847

Gene position: 408392-406608 (Counterclockwise)

Preceding gene: 34495850

Following gene: 34495840

Centisome position: 8.6

GC content: 74.96

Gene sequence:

>1785_bases
TTGCCCGGCCAGGCGCTGCCGCCGTCCATCCTGCATTCCTGGCAGCGCTGCCGCGGCCTGGGGCTGCCCGCCGGCGGCCG
CGGCGGCGATCGGCTGACCGACGGCGAGCTGCGCGAGCGGCGCGATGCCAGCGCGGCCTGGCTGGAGCCGTCGCGGCCGG
CGCTGGCCGGACTGTTCGAACAGGTCAGCGCGCAGGGACTGGCGCTGGTGGTCGCGGACCGGAACGGGTGGATACTGGAT
CAGAGCGGCGACATCGGCTTTCTCGACAAGGCCGAGCGGCTGGCGCTGACGCCGGGCATGGACTGGAGCGAGGCCGCGCG
CGGCACCAATGCGATCGGCACCGCGCTGGCCGCGGCCGACAGCGTGCTGGTGCGCGGCGCCGAGCACTACCTGGAACGCA
ACCGGGCGCTCAGTTGCGCCGCCAGCCCGCTGTTCGGCCCCCAGGGCCAGCTGCTGGGGGTGCTAGACATCAGCGGCCCC
GGCCGCAAGCTGGGCGACGCGCAGCGGCTGGCGCTGCAGGCCGCCCGCGCGCAGATCGAGGCGCGGCAGCTGGAGGACGC
CGCCCGCCATGGCTGGCTGTTCCGGCTCCACGCCGATCCGCGTTGGCTGGACAGCCCCGCCGCCTGCCAGCTGGCGTTCG
ACGGCGACGGCCGGCTGCTGGCCGCCAATCGCGCCGGTCTGACGCTGTGCGGACTGGAACCGGGCGACTGGCAGCCGCGC
CACTTCGCCGCGCTGTTCGGCCAGAGCCTGGAGCATTGGCTGGAGCGCCACGGCCAGGCGGCCGGCCTGCTTAGCCTGGG
CCAGCAGCGGCTGTCTGCCCGGCTGCGGCCGCCGCCATCCCGCCGTCCGTCCGCGCCCGCGCGCGCGGCGTTGCCCAGCG
CCCCGCGCGCGTCTTCCGCCCCCGGACTGGACGGCCTGCCGGACTGGCTGTTTCCCACCGCGCTCAAACTGCTGGAAGCC
GATATCCCGGTCTTGCTGCTGGGCGAAACCGGCACCGGCAAGGACAGGCTGGCGCGCGCGCTGCACCAGGCCGGCAGCCG
GCGCGGCGCGCCCTTCGTGGCGGTCAACTGCGCGGCGATACCGGAAGGGCTGGTCGAGGCCGAACTGTTCGGCTACCAGC
CCGGCGCCTACACCGGCGCCAGCCGCCAGGGCAGCAAGGGACGGCTGCGCGAGGCCGATGGCGGCGTGCTGTTCCTGGAT
GAAATCGGCGACATGCCGCTGAGCCTGCAGGCGCGGCTGCTCAGGGTGCTGCAGGACCGGGAAGTGACGCCGCTGGGCGG
CGGGCCGGCACACAGGCTGGACATCCGGCTGATCTGCGCCACCCACCGCGACCTGCGCGCGCGCGTGGACGACGGCGGCT
TCCGCGCCGATCTCTACTACCGGCTGTGCCACTATCCGCTGCGGCTGCCGCCGCTGCGCGAGCGCGGCGACGTCGCGGCC
ATCGCCCAGGCCATGCTGGACGGCCTGGGCGCGGGCCGGCGCGGCATCTCGCTGACGCCGGAGCTGGCGCGCGCGCTGCG
CGGCTACCGCTGGCCCGGCAATCTGCGCGAGCTGTCCAATCTGCTGGCCACGCTGCTGGCGCTGGCCGACGACGGCGCGG
CGCTGGACGTCGAACACCTGCCCGCCGACCTGCGCGATGACATGGCGGCGCAGGGGCATGCGGTGGCGGACAACGCCATC
GCCGAGCTGCTGCGCCGCTGCGGCGGCAACGCCAGCGCGGCGGCGCGGGCGCTGGGCATCAGCCGATCGACGCTGTACCG
GCGGCTGGGCAAGACTTCCAAGTAA

Upstream 100 bases:

>100_bases
TGTCCCGCCCCCGCGCGACACCTCGCCGGAGCCGAGCATGAAGCCCACCGCCCGCCTGCCGCTGGATGAAATCCGCCGCC
GCTTCTTCTCCGACCAGCCC

Downstream 100 bases:

>100_bases
CCGCTGCCGCAAATAATCAGCCCGAAAGCGCGCCCGCTCAGCTGCGCGGCAAGGCATGCCGCCGCTCATGCGCCAACAAC
CATTGCTTGCGTGCCAAGCC

Product: transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 593

Protein sequence:

>594_residues
MPGQALPPSILHSWQRCRGLGLPAGGRGGDRLTDGELRERRDASAAWLEPSRPALAGLFEQVSAQGLALVVADRNGWILD
QSGDIGFLDKAERLALTPGMDWSEAARGTNAIGTALAAADSVLVRGAEHYLERNRALSCAASPLFGPQGQLLGVLDISGP
GRKLGDAQRLALQAARAQIEARQLEDAARHGWLFRLHADPRWLDSPAACQLAFDGDGRLLAANRAGLTLCGLEPGDWQPR
HFAALFGQSLEHWLERHGQAAGLLSLGQQRLSARLRPPPSRRPSAPARAALPSAPRASSAPGLDGLPDWLFPTALKLLEA
DIPVLLLGETGTGKDRLARALHQAGSRRGAPFVAVNCAAIPEGLVEAELFGYQPGAYTGASRQGSKGRLREADGGVLFLD
EIGDMPLSLQARLLRVLQDREVTPLGGGPAHRLDIRLICATHRDLRARVDDGGFRADLYYRLCHYPLRLPPLRERGDVAA
IAQAMLDGLGAGRRGISLTPELARALRGYRWPGNLRELSNLLATLLALADDGAALDVEHLPADLRDDMAAQGHAVADNAI
AELLRRCGGNASAAARALGISRSTLYRRLGKTSK

Sequences:

>Translated_594_residues
MPGQALPPSILHSWQRCRGLGLPAGGRGGDRLTDGELRERRDASAAWLEPSRPALAGLFEQVSAQGLALVVADRNGWILD
QSGDIGFLDKAERLALTPGMDWSEAARGTNAIGTALAAADSVLVRGAEHYLERNRALSCAASPLFGPQGQLLGVLDISGP
GRKLGDAQRLALQAARAQIEARQLEDAARHGWLFRLHADPRWLDSPAACQLAFDGDGRLLAANRAGLTLCGLEPGDWQPR
HFAALFGQSLEHWLERHGQAAGLLSLGQQRLSARLRPPPSRRPSAPARAALPSAPRASSAPGLDGLPDWLFPTALKLLEA
DIPVLLLGETGTGKDRLARALHQAGSRRGAPFVAVNCAAIPEGLVEAELFGYQPGAYTGASRQGSKGRLREADGGVLFLD
EIGDMPLSLQARLLRVLQDREVTPLGGGPAHRLDIRLICATHRDLRARVDDGGFRADLYYRLCHYPLRLPPLRERGDVAA
IAQAMLDGLGAGRRGISLTPELARALRGYRWPGNLRELSNLLATLLALADDGAALDVEHLPADLRDDMAAQGHAVADNAI
AELLRRCGGNASAAARALGISRSTLYRRLGKTSK
>Mature_593_residues
PGQALPPSILHSWQRCRGLGLPAGGRGGDRLTDGELRERRDASAAWLEPSRPALAGLFEQVSAQGLALVVADRNGWILDQ
SGDIGFLDKAERLALTPGMDWSEAARGTNAIGTALAAADSVLVRGAEHYLERNRALSCAASPLFGPQGQLLGVLDISGPG
RKLGDAQRLALQAARAQIEARQLEDAARHGWLFRLHADPRWLDSPAACQLAFDGDGRLLAANRAGLTLCGLEPGDWQPRH
FAALFGQSLEHWLERHGQAAGLLSLGQQRLSARLRPPPSRRPSAPARAALPSAPRASSAPGLDGLPDWLFPTALKLLEAD
IPVLLLGETGTGKDRLARALHQAGSRRGAPFVAVNCAAIPEGLVEAELFGYQPGAYTGASRQGSKGRLREADGGVLFLDE
IGDMPLSLQARLLRVLQDREVTPLGGGPAHRLDIRLICATHRDLRARVDDGGFRADLYYRLCHYPLRLPPLRERGDVAAI
AQAMLDGLGAGRRGISLTPELARALRGYRWPGNLRELSNLLATLLALADDGAALDVEHLPADLRDDMAAQGHAVADNAIA
ELLRRCGGNASAAARALGISRSTLYRRLGKTSK

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=417, Percent_Identity=35.9712230215827, Blast_Score=231, Evalue=9e-62,
Organism=Escherichia coli, GI1788550, Length=287, Percent_Identity=42.5087108013937, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI87082117, Length=297, Percent_Identity=43.4343434343434, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI1790437, Length=279, Percent_Identity=41.9354838709677, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1789087, Length=207, Percent_Identity=50.2415458937198, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1790299, Length=337, Percent_Identity=38.8724035608309, Blast_Score=195, Evalue=6e-51,
Organism=Escherichia coli, GI1786524, Length=299, Percent_Identity=41.4715719063545, Blast_Score=192, Evalue=7e-50,
Organism=Escherichia coli, GI1788905, Length=295, Percent_Identity=38.9830508474576, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI87082152, Length=296, Percent_Identity=39.8648648648649, Blast_Score=178, Evalue=8e-46,
Organism=Escherichia coli, GI87081872, Length=209, Percent_Identity=44.4976076555024, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1787583, Length=221, Percent_Identity=42.0814479638009, Blast_Score=159, Evalue=5e-40,
Organism=Escherichia coli, GI1789828, Length=258, Percent_Identity=35.6589147286822, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI87081858, Length=288, Percent_Identity=32.6388888888889, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 63430; Mature: 63299

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGQALPPSILHSWQRCRGLGLPAGGRGGDRLTDGELRERRDASAAWLEPSRPALAGLFE
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHH
QVSAQGLALVVADRNGWILDQSGDIGFLDKAERLALTPGMDWSEAARGTNAIGTALAAAD
HHCCCCEEEEEECCCCEEEECCCCCCCCCCCCCEEECCCCCHHHHHCCCHHHHHHHHHHH
SVLVRGAEHYLERNRALSCAASPLFGPQGQLLGVLDISGPGRKLGDAQRLALQAARAQIE
HHHHHHHHHHHHHCCHHHHHCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
ARQLEDAARHGWLFRLHADPRWLDSPAACQLAFDGDGRLLAANRAGLTLCGLEPGDWQPR
HHHHHHHHHCCEEEEEECCCCCCCCCCEEEEEECCCCCEEEECCCCEEEECCCCCCCCHH
HFAALFGQSLEHWLERHGQAAGLLSLGQQRLSARLRPPPSRRPSAPARAALPSAPRASSA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCCCC
PGLDGLPDWLFPTALKLLEADIPVLLLGETGTGKDRLARALHQAGSRRGAPFVAVNCAAI
CCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHC
PEGLVEAELFGYQPGAYTGASRQGSKGRLREADGGVLFLDEIGDMPLSLQARLLRVLQDR
CCHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCEEEECCCCCCCHHHHHHHHHHHHCC
EVTPLGGGPAHRLDIRLICATHRDLRARVDDGGFRADLYYRLCHYPLRLPPLRERGDVAA
CCCCCCCCCCCEEEEEEEEECCCHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHH
IAQAMLDGLGAGRRGISLTPELARALRGYRWPGNLRELSNLLATLLALADDGAALDVEHL
HHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHC
PADLRDDMAAQGHAVADNAIAELLRRCGGNASAAARALGISRSTLYRRLGKTSK
CCHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
PGQALPPSILHSWQRCRGLGLPAGGRGGDRLTDGELRERRDASAAWLEPSRPALAGLFE
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHH
QVSAQGLALVVADRNGWILDQSGDIGFLDKAERLALTPGMDWSEAARGTNAIGTALAAAD
HHCCCCEEEEEECCCCEEEECCCCCCCCCCCCCEEECCCCCHHHHHCCCHHHHHHHHHHH
SVLVRGAEHYLERNRALSCAASPLFGPQGQLLGVLDISGPGRKLGDAQRLALQAARAQIE
HHHHHHHHHHHHHCCHHHHHCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
ARQLEDAARHGWLFRLHADPRWLDSPAACQLAFDGDGRLLAANRAGLTLCGLEPGDWQPR
HHHHHHHHHCCEEEEEECCCCCCCCCCEEEEEECCCCCEEEECCCCEEEECCCCCCCCHH
HFAALFGQSLEHWLERHGQAAGLLSLGQQRLSARLRPPPSRRPSAPARAALPSAPRASSA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCCCC
PGLDGLPDWLFPTALKLLEADIPVLLLGETGTGKDRLARALHQAGSRRGAPFVAVNCAAI
CCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHC
PEGLVEAELFGYQPGAYTGASRQGSKGRLREADGGVLFLDEIGDMPLSLQARLLRVLQDR
CCHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCEEEECCCCCCCHHHHHHHHHHHHCC
EVTPLGGGPAHRLDIRLICATHRDLRARVDDGGFRADLYYRLCHYPLRLPPLRERGDVAA
CCCCCCCCCCCEEEEEEEEECCCHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHH
IAQAMLDGLGAGRRGISLTPELARALRGYRWPGNLRELSNLLATLLALADDGAALDVEHL
HHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHC
PADLRDDMAAQGHAVADNAIAELLRRCGGNASAAARALGISRSTLYRRLGKTSK
CCHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]