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The map label for this gene is sdaA [H]

Identifier: 339717968

GI number: 339717968

Start: 596679

End: 598154

Strand: Direct

Name: sdaA [H]

Synonym: NA

Alternate gene names: 339717968

Gene position: 596679-598154 (Clockwise)

Preceding gene: 238023946

Following gene: 238023949

Centisome position: 21.1

GC content: 67.68

Gene sequence:

>1476_bases
ATGCCGTTTTTGTTCTATCGGCGGATTTTACGCTTTGATGTACTGACGCCCAGTGTCCAACCGTTGCGTATCCACCGGAG
AAGCAGTCAGATGAACGTCAGCGTTTTCGATCTGTTCAAGATCGGCATCGGTCCGTCGAGCTCGCATACGGTCGGTCCGA
TGATCGCGGCCTGCCGGTTCGCCTCGCACGTGGAGGACGCCAACCTGCTGGCGTTCGTGCGCCGCGTGCGGGTCGAGCTG
TACGGCTCGCTCGGCGCGACGGGCAAGGGCCACGGCACCGACAAGGCGGTGCTGCTCGGCCTGGAGGGCCATCTGCCCGA
CCTGATCGACCCCGACCTGATCGAGCCGCGCCTGAAGGCGATCCGCGCCGAAAGGACGCTCAACCTGCTGGGCCGGCACG
CGGTGCGCTTCGAGGAGAAGGAAGACCTGGGCTTCTACCGCCGCATGATGGCCTGCACCGGCATCGTGCACCCGAACGGC
ATGCGCTTCCAGGCGTTCGACGAGCACGGCCAGCTGCTGGTGGAGAAGGAGTATTACTCGGTGGGCGGCGGCTTCGTGGT
GAACCGCGACGGCGACCGCGTAAACGGCGTGCGCGCGGCCGTCGACGTGCCGTATCCGTTCCGCACCGGCAGCGACCTGC
TGCGTGCCTGTCGCGAGAGCGGCCTGTCGATCGCCGAGCTGACGTTGCGCAACGAATGCGCGCTGCGCCCGGCCGAGGAA
GTGCGCGCCGGGCTGCTGGCGATCTGGCGGACCATGGCGGCCTGCGTCGAGCGCGGCTGCAAGGTGGAGGGCGACCTGCC
GGGCCCGATGCGCGTCAAGCGCCGCGCGGCCGATCTCTACAACCGCCTGCGCAGCCGCTCCGAGGAATCGCTGCGCGATC
CGCTGTCGATGCTCGACTGGGTCAACCTCTACGCGATGGCCGTGAACGAGGAGAACGCCGCGGGCGGCCGGGTGGTGACG
GCACCCACCAACGGCGCGGCCGGCGTGATCCCGGCGGTGCTGCACTACTACGTGAAGTTCGTGCCGGGCTCGGACGAGCA
GGGCATCGTCGAGTTCCTGCTGACGGCCGCCGCGATCGGCATCATCTACAAGGAAACCGCCTCGATCTCGGGCGCCGAGG
TGGGCTGCCAGGGCGAGGTGGGGGTGGCCTGCTCGATGGCCGCCGCCGCGCTCGCCGCCGTGATGGGCGGCAATCCCGAC
CAGGTCGAGAACGCCGCCGAGATCGGCATGGAGCACAACCTCGGCATGACCTGCGACCCGGTGGGCGGCCTGGTGCAGAT
TCCCTGCATCGAGCGCAACGCGATGGGCGCGATCAAGGCGCTGAACGCCTCGCGCATGGCGCTCAAGGGCGACGGCCAGC
ACTACGTGTCGCTCGATTCGGTGATCAAGACGATGCGCGAGACCGGCGCCGACATGAAGACGAAATACAAGGAGACGTCG
CGCGGTGGCCTCGCCGTGAACGTCATCGAATGCTAA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: L-serine ammonia-lyase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:
NA

Sequences:

>Translated_491_residues
MPFLFYRRILRFDVLTPSVQPLRIHRRSSQMNVSVFDLFKIGIGPSSSHTVGPMIAACRFASHVEDANLLAFVRRVRVEL
YGSLGATGKGHGTDKAVLLGLEGHLPDLIDPDLIEPRLKAIRAERTLNLLGRHAVRFEEKEDLGFYRRMMACTGIVHPNG
MRFQAFDEHGQLLVEKEYYSVGGGFVVNRDGDRVNGVRAAVDVPYPFRTGSDLLRACRESGLSIAELTLRNECALRPAEE
VRAGLLAIWRTMAACVERGCKVEGDLPGPMRVKRRAADLYNRLRSRSEESLRDPLSMLDWVNLYAMAVNEENAAGGRVVT
APTNGAAGVIPAVLHYYVKFVPGSDEQGIVEFLLTAAAIGIIYKETASISGAEVGCQGEVGVACSMAAAALAAVMGGNPD
QVENAAEIGMEHNLGMTCDPVGGLVQIPCIERNAMGAIKALNASRMALKGDGQHYVSLDSVIKTMRETGADMKTKYKETS
RGGLAVNVIEC
>Mature_490_residues
PFLFYRRILRFDVLTPSVQPLRIHRRSSQMNVSVFDLFKIGIGPSSSHTVGPMIAACRFASHVEDANLLAFVRRVRVELY
GSLGATGKGHGTDKAVLLGLEGHLPDLIDPDLIEPRLKAIRAERTLNLLGRHAVRFEEKEDLGFYRRMMACTGIVHPNGM
RFQAFDEHGQLLVEKEYYSVGGGFVVNRDGDRVNGVRAAVDVPYPFRTGSDLLRACRESGLSIAELTLRNECALRPAEEV
RAGLLAIWRTMAACVERGCKVEGDLPGPMRVKRRAADLYNRLRSRSEESLRDPLSMLDWVNLYAMAVNEENAAGGRVVTA
PTNGAAGVIPAVLHYYVKFVPGSDEQGIVEFLLTAAAIGIIYKETASISGAEVGCQGEVGVACSMAAAALAAVMGGNPDQ
VENAAEIGMEHNLGMTCDPVGGLVQIPCIERNAMGAIKALNASRMALKGDGQHYVSLDSVIKTMRETGADMKTKYKETSR
GGLAVNVIEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1789161, Length=462, Percent_Identity=52.3809523809524, Blast_Score=469, Evalue=1e-133,
Organism=Escherichia coli, GI1788116, Length=460, Percent_Identity=51.7391304347826, Blast_Score=464, Evalue=1e-132,
Organism=Escherichia coli, GI48994925, Length=458, Percent_Identity=52.8384279475983, Blast_Score=454, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 53305; Mature: 53174

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: PS00159 ALDOLASE_KDPG_KHG_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFLFYRRILRFDVLTPSVQPLRIHRRSSQMNVSVFDLFKIGIGPSSSHTVGPMIAACRF
CCHHHHHHHHHHHHCCCCCCHHHEEECCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHH
ASHVEDANLLAFVRRVRVELYGSLGATGKGHGTDKAVLLGLEGHLPDLIDPDLIEPRLKA
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHH
IRAERTLNLLGRHAVRFEEKEDLGFYRRMMACTGIVHPNGMRFQAFDEHGQLLVEKEYYS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEHHEE
VGGGFVVNRDGDRVNGVRAAVDVPYPFRTGSDLLRACRESGLSIAELTLRNECALRPAEE
CCCCEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEEECCHHCCCCHHH
VRAGLLAIWRTMAACVERGCKVEGDLPGPMRVKRRAADLYNRLRSRSEESLRDPLSMLDW
HHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VNLYAMAVNEENAAGGRVVTAPTNGAAGVIPAVLHYYVKFVPGSDEQGIVEFLLTAAAIG
HHHHEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHH
IIYKETASISGAEVGCQGEVGVACSMAAAALAAVMGGNPDQVENAAEIGMEHNLGMTCDP
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCC
VGGLVQIPCIERNAMGAIKALNASRMALKGDGQHYVSLDSVIKTMRETGADMKTKYKETS
CCCEEECCEECCCHHHHHHHCCCCCEEEECCCCEEEEHHHHHHHHHHCCCCHHHHHHHCC
RGGLAVNVIEC
CCCEEEEEECC
>Mature Secondary Structure 
PFLFYRRILRFDVLTPSVQPLRIHRRSSQMNVSVFDLFKIGIGPSSSHTVGPMIAACRF
CHHHHHHHHHHHHCCCCCCHHHEEECCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHH
ASHVEDANLLAFVRRVRVELYGSLGATGKGHGTDKAVLLGLEGHLPDLIDPDLIEPRLKA
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHH
IRAERTLNLLGRHAVRFEEKEDLGFYRRMMACTGIVHPNGMRFQAFDEHGQLLVEKEYYS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEHHEE
VGGGFVVNRDGDRVNGVRAAVDVPYPFRTGSDLLRACRESGLSIAELTLRNECALRPAEE
CCCCEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEEECCHHCCCCHHH
VRAGLLAIWRTMAACVERGCKVEGDLPGPMRVKRRAADLYNRLRSRSEESLRDPLSMLDW
HHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VNLYAMAVNEENAAGGRVVTAPTNGAAGVIPAVLHYYVKFVPGSDEQGIVEFLLTAAAIG
HHHHEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHH
IIYKETASISGAEVGCQGEVGVACSMAAAALAAVMGGNPDQVENAAEIGMEHNLGMTCDP
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCC
VGGLVQIPCIERNAMGAIKALNASRMALKGDGQHYVSLDSVIKTMRETGADMKTKYKETS
CCCEEECCEECCCHHHHHHHCCCCCEEEECCCCEEEEHHHHHHHHHHCCCCHHHHHHHCC
RGGLAVNVIEC
CCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]