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The map label for this gene is nagA [H]

Identifier: 33864304

GI number: 33864304

Start: 2152189

End: 2153394

Strand: Direct

Name: nagA [H]

Synonym: PMT2039

Alternate gene names: 33864304

Gene position: 2152189-2153394 (Clockwise)

Preceding gene: 33864301

Following gene: 33864305

Centisome position: 89.27

GC content: 57.71

Gene sequence:

>1206_bases
ATGACGACAATGCCATGGTCCCGCACTAGCACCGCCTGGCCACCTCCCATGCATCGGATCACCCACATCCGCCTGCCCGA
ACCTCTCAACAAAGCCGTGGACACCAAGCTGTGGTGGATGGCCGTAGATGAGCACGAGCGGGTGCTCAGTGTTCAACCCA
TGGCAGATGGCTCTGCCATGGACGGGGAGAGCTGGCAGGGCGACTGGCTCAGCCCCATGGGCATCGATCTACAAATCAAT
GGAGGGCTGGGATTGGCCTTCCCCGAGCTCACCGCCAAAGACATTCCCCAGCTCCTGAAGCTGCTCGACAGACTCTGGCA
AGACGGTGTACAGGCAATCTGCCCCACGGTTGTGAGCTGCGGCGTAGCAGCCCTGCGTCAATCTTTAACGGTGCTGCATG
CAGCCCGAGAACAACACTGCCCGCAACGCTGTGAACTACTAGGGGCCCACCTTGAAGGCCCTTTTCTGGCAACAGCACGC
CACGGCGCCCATCCCCTGGAGCATCTCTGTGCTCCGAGCCTAAGGGCACTGGATGAACGCATTCGCGGCTTTGAGCAAGA
CATCAGTTTGATGACCCTGGCTCCAGAACTGCCCGGATCATCTGAAGTGATTGAACGACTAAGGACCCTAGGCATCGTGA
TATGCCTAGGGCACTCGAACGCAGATGGGGAAGCCTCTGCCGATGCCTTCTCCCAGGGAGTGGGAATGCTGACCCACTCC
TTCAATGCCATGCCCGGTCTTCATCATCGTGCAGCTGGCCCGGTGGGGGAAGCCTGCATGCATGGAGAAATCGCTATGGG
ACTAATCGCCGATGGAGTTCATGTTGACCCCACCATGGCGGTGCTATTGCAAAGACTGGCACCACAACAGCTGATACTTG
TGAGCGATAGTCTCGCTCCCTACGGCCTCAAAGATGGCAAATATCGCTGGGATGAAAGAGTTCTGCTGGTCGAAAAAGGA
ACCTGTCGTTTGGAAGATGGCACTCTGGCAGGAGTCACATTGCCGCTCCTGGAAGGGAGTCGACGTTTAGCCACTTGGAG
TGGTGAACCTGCCGCGGCCATCTGGGCTGCCACCATGGCCCCTCGTCAGGTGATGGGCAATGGCCGCACACTGGATGAGC
TACTTGTGAATCAGCCCTTAACAGACTTACTCCGCTGGCAGTGGAAACCGGATACTGAAGAGCTGATCTGGAAGCATGCT
GCTTAA

Upstream 100 bases:

>100_bases
GTTGGCAAATCAGAATCACTACCCATCACCACAGCCACCTGCGGCGGCGATTCAGCAGCTGCCAAAGGCACAGGCAGAGA
AGCAGAGGTCACGATGAATA

Downstream 100 bases:

>100_bases
GATCCCGATCGTCTGAACCCAACTCAATGGCCATGGAACAGCGCCAAGAGCTCAAACAGGCCGAAAAAACTGAAGTAGCC
AACTACTTCAACGGAACAGG

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MTTMPWSRTSTAWPPPMHRITHIRLPEPLNKAVDTKLWWMAVDEHERVLSVQPMADGSAMDGESWQGDWLSPMGIDLQIN
GGLGLAFPELTAKDIPQLLKLLDRLWQDGVQAICPTVVSCGVAALRQSLTVLHAAREQHCPQRCELLGAHLEGPFLATAR
HGAHPLEHLCAPSLRALDERIRGFEQDISLMTLAPELPGSSEVIERLRTLGIVICLGHSNADGEASADAFSQGVGMLTHS
FNAMPGLHHRAAGPVGEACMHGEIAMGLIADGVHVDPTMAVLLQRLAPQQLILVSDSLAPYGLKDGKYRWDERVLLVEKG
TCRLEDGTLAGVTLPLLEGSRRLATWSGEPAAAIWAATMAPRQVMGNGRTLDELLVNQPLTDLLRWQWKPDTEELIWKHA
A

Sequences:

>Translated_401_residues
MTTMPWSRTSTAWPPPMHRITHIRLPEPLNKAVDTKLWWMAVDEHERVLSVQPMADGSAMDGESWQGDWLSPMGIDLQIN
GGLGLAFPELTAKDIPQLLKLLDRLWQDGVQAICPTVVSCGVAALRQSLTVLHAAREQHCPQRCELLGAHLEGPFLATAR
HGAHPLEHLCAPSLRALDERIRGFEQDISLMTLAPELPGSSEVIERLRTLGIVICLGHSNADGEASADAFSQGVGMLTHS
FNAMPGLHHRAAGPVGEACMHGEIAMGLIADGVHVDPTMAVLLQRLAPQQLILVSDSLAPYGLKDGKYRWDERVLLVEKG
TCRLEDGTLAGVTLPLLEGSRRLATWSGEPAAAIWAATMAPRQVMGNGRTLDELLVNQPLTDLLRWQWKPDTEELIWKHA
A
>Mature_400_residues
TTMPWSRTSTAWPPPMHRITHIRLPEPLNKAVDTKLWWMAVDEHERVLSVQPMADGSAMDGESWQGDWLSPMGIDLQING
GLGLAFPELTAKDIPQLLKLLDRLWQDGVQAICPTVVSCGVAALRQSLTVLHAAREQHCPQRCELLGAHLEGPFLATARH
GAHPLEHLCAPSLRALDERIRGFEQDISLMTLAPELPGSSEVIERLRTLGIVICLGHSNADGEASADAFSQGVGMLTHSF
NAMPGLHHRAAGPVGEACMHGEIAMGLIADGVHVDPTMAVLLQRLAPQQLILVSDSLAPYGLKDGKYRWDERVLLVEKGT
CRLEDGTLAGVTLPLLEGSRRLATWSGEPAAAIWAATMAPRQVMGNGRTLDELLVNQPLTDLLRWQWKPDTEELIWKHAA

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI224922791, Length=259, Percent_Identity=35.5212355212355, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI21361513, Length=380, Percent_Identity=31.3157894736842, Blast_Score=138, Evalue=8e-33,
Organism=Escherichia coli, GI1786892, Length=342, Percent_Identity=30.7017543859649, Blast_Score=140, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17553768, Length=363, Percent_Identity=30.0275482093664, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI19920392, Length=309, Percent_Identity=35.2750809061489, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI281361140, Length=323, Percent_Identity=33.7461300309598, Blast_Score=137, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 43855; Mature: 43724

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTMPWSRTSTAWPPPMHRITHIRLPEPLNKAVDTKLWWMAVDEHERVLSVQPMADGSAM
CCCCCCCCCCCCCCCCHHHEEEEECCCHHHHHHCCEEEEEEECCCCCEEEECCCCCCCCC
DGESWQGDWLSPMGIDLQINGGLGLAFPELTAKDIPQLLKLLDRLWQDGVQAICPTVVSC
CCCCCCCCCCCCCCEEEEECCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVAALRQSLTVLHAAREQHCPQRCELLGAHLEGPFLATARHGAHPLEHLCAPSLRALDER
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHCCHHHHHHHHH
IRGFEQDISLMTLAPELPGSSEVIERLRTLGIVICLGHSNADGEASADAFSQGVGMLTHS
HHHHHHCCEEEEECCCCCCHHHHHHHHHHCEEEEEEECCCCCCCCHHHHHHHCHHHHHHH
FNAMPGLHHRAAGPVGEACMHGEIAMGLIADGVHVDPTMAVLLQRLAPQQLILVSDSLAP
CCCCCCCHHHCCCCHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEECCCCC
YGLKDGKYRWDERVLLVEKGTCRLEDGTLAGVTLPLLEGSRRLATWSGEPAAAIWAATMA
CCCCCCCEECCCEEEEEECCCEEECCCCEEEEEEEECCCCCEEEECCCCCHHHHHHHHHC
PRQVMGNGRTLDELLVNQPLTDLLRWQWKPDTEELIWKHAA
CHHHHCCCCCHHHHHHCCCHHHHHHCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
TTMPWSRTSTAWPPPMHRITHIRLPEPLNKAVDTKLWWMAVDEHERVLSVQPMADGSAM
CCCCCCCCCCCCCCCHHHEEEEECCCHHHHHHCCEEEEEEECCCCCEEEECCCCCCCCC
DGESWQGDWLSPMGIDLQINGGLGLAFPELTAKDIPQLLKLLDRLWQDGVQAICPTVVSC
CCCCCCCCCCCCCCEEEEECCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVAALRQSLTVLHAAREQHCPQRCELLGAHLEGPFLATARHGAHPLEHLCAPSLRALDER
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHCCHHHHHHHHH
IRGFEQDISLMTLAPELPGSSEVIERLRTLGIVICLGHSNADGEASADAFSQGVGMLTHS
HHHHHHCCEEEEECCCCCCHHHHHHHHHHCEEEEEEECCCCCCCCHHHHHHHCHHHHHHH
FNAMPGLHHRAAGPVGEACMHGEIAMGLIADGVHVDPTMAVLLQRLAPQQLILVSDSLAP
CCCCCCCHHHCCCCHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEECCCCC
YGLKDGKYRWDERVLLVEKGTCRLEDGTLAGVTLPLLEGSRRLATWSGEPAAAIWAATMA
CCCCCCCEECCCEEEEEECCCEEECCCCEEEEEEEECCCCCEEEECCCCCHHHHHHHHHC
PRQVMGNGRTLDELLVNQPLTDLLRWQWKPDTEELIWKHAA
CHHHHCCCCCHHHHHHCCCHHHHHHCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]