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The map label for this gene is rodA [H]

Identifier: 33863975

GI number: 33863975

Start: 1807386

End: 1808669

Strand: Direct

Name: rodA [H]

Synonym: PMT1708

Alternate gene names: 33863975

Gene position: 1807386-1808669 (Clockwise)

Preceding gene: 33863974

Following gene: 33863976

Centisome position: 74.97

GC content: 56.54

Gene sequence:

>1284_bases
ATGCTTTCAAGCCAGAGGCGGCGACGCAATGGTGGCAAGTCCTTCCGTTCTAAGGGGCATCTACGTAGATGGTGGAAAGA
ACTGGATCTAGTGCTCTGGGGGGTGCCAGTGGCCATGGTGATCCTTGCGGGCGTCCTGATCGCCAGCACTCAAAGACAGG
CTGATTACGCCGACTGGTATCACCACTGGATCACCGCTGGATTGGGATGCTTGGTCGCTCTGTTGCTGGCCCGATTGCCA
GTCCAGAGACTGCGGCCGCTATTAATTCCCCTCTACGCACTTACAGTTCTGAGCCTGGTAGCCGTTCGCCTAATCGGCAC
CTCCGCCCTAGGCGCTCAGCGGTGGATCAGCATCGCTGGGGTGAATGTTCAGCCATCTGAATTCGCCAAACTGGCAGCAA
TACTCCTTTTGGCAGCAGTACTCGACCGCCACCCGATAGAACGCCCCATCGACCTGATGAGGCCTTTGGCCGTGATTTCT
GTGCCCTGGACACTGGTCTTCCTGCAACCGGATCTCGGCAGTTCACTCGTGTTCGGCGCCCTGCTAGTGACAATGCTCTA
TTGGGCTGACATGCCCTGGGAATGGGTCCTGTTGCTCCTATCACCTCTAGCCACAGCACTCCTTGCGGGGCTATGGCCTT
GGACTCTCTGCGCATGGCTCCCTCTGATGGGTTTGCTGGCCTATCGCTCACTGCCATGGAAACGCCTGGCCGCTTCGCTC
ACTTTGGCGCTGCAAGGAATCGTGGCTGTTACCACCCCTTGGCTTTGGTTGCATGGCCTCAAGGACTATCAAAGAGAACG
GCTAGTGCTGTTTCTCGATCCCACCAAAGACCCCCTAGGTGGTGGCTATCACCTCCTGCAAAGCACTGTGGGCATTGGCT
CTGGCGGGCTATTTGGCACAGGGCTGCTGCAAGGTCAACTCACCAAGCTCCGTTTCATCCCCGAGCAGCACACCGATTTC
ATCTTCAGTGCCCTAGGGGAAGAAACTGGCTTCATCGGGACCATCCTTGTCGTAACAGGCTTCGCGCTACTCATGGGACG
CCTACTACAAGTTGCCAGAGAAGCCCGCACTGACTTCGAATCACTGGTTGTCATAGGCGTCGCCACGATGGTGATGTTCC
AAGTGGTCGTGAACATCTTTATGACCATTGGCCTTGGCCCTGTCACTGGCATCCCCTTACCATTTATGAGCTATGGCCGC
TCAGCAATGGTGGTGAACTTCGTAGCACTTGGACTCTGCCTTTCGGTGGCACGCCGAGGTCACACAAGACTCAACAACTG
GTGA

Upstream 100 bases:

>100_bases
GTAGCCCCATCGTTCATAGCCGACCCGAATCAGTGAGTGCCAAAGCCTTCAAGCAATTAGCCAAACAAGTTCTGGATTGC
GCCTCCAAGGCCAGCTGACC

Downstream 100 bases:

>100_bases
GCGATTCCATCTCGCTCATCACGATCCAACAACGGCTTGCAGAAGGTGTCACTCCTGGCCGCGTCGATGAAGCCACCGTT
CGACGCCTGTGGTGGGCAGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MLSSQRRRRNGGKSFRSKGHLRRWWKELDLVLWGVPVAMVILAGVLIASTQRQADYADWYHHWITAGLGCLVALLLARLP
VQRLRPLLIPLYALTVLSLVAVRLIGTSALGAQRWISIAGVNVQPSEFAKLAAILLLAAVLDRHPIERPIDLMRPLAVIS
VPWTLVFLQPDLGSSLVFGALLVTMLYWADMPWEWVLLLLSPLATALLAGLWPWTLCAWLPLMGLLAYRSLPWKRLAASL
TLALQGIVAVTTPWLWLHGLKDYQRERLVLFLDPTKDPLGGGYHLLQSTVGIGSGGLFGTGLLQGQLTKLRFIPEQHTDF
IFSALGEETGFIGTILVVTGFALLMGRLLQVAREARTDFESLVVIGVATMVMFQVVVNIFMTIGLGPVTGIPLPFMSYGR
SAMVVNFVALGLCLSVARRGHTRLNNW

Sequences:

>Translated_427_residues
MLSSQRRRRNGGKSFRSKGHLRRWWKELDLVLWGVPVAMVILAGVLIASTQRQADYADWYHHWITAGLGCLVALLLARLP
VQRLRPLLIPLYALTVLSLVAVRLIGTSALGAQRWISIAGVNVQPSEFAKLAAILLLAAVLDRHPIERPIDLMRPLAVIS
VPWTLVFLQPDLGSSLVFGALLVTMLYWADMPWEWVLLLLSPLATALLAGLWPWTLCAWLPLMGLLAYRSLPWKRLAASL
TLALQGIVAVTTPWLWLHGLKDYQRERLVLFLDPTKDPLGGGYHLLQSTVGIGSGGLFGTGLLQGQLTKLRFIPEQHTDF
IFSALGEETGFIGTILVVTGFALLMGRLLQVAREARTDFESLVVIGVATMVMFQVVVNIFMTIGLGPVTGIPLPFMSYGR
SAMVVNFVALGLCLSVARRGHTRLNNW
>Mature_427_residues
MLSSQRRRRNGGKSFRSKGHLRRWWKELDLVLWGVPVAMVILAGVLIASTQRQADYADWYHHWITAGLGCLVALLLARLP
VQRLRPLLIPLYALTVLSLVAVRLIGTSALGAQRWISIAGVNVQPSEFAKLAAILLLAAVLDRHPIERPIDLMRPLAVIS
VPWTLVFLQPDLGSSLVFGALLVTMLYWADMPWEWVLLLLSPLATALLAGLWPWTLCAWLPLMGLLAYRSLPWKRLAASL
TLALQGIVAVTTPWLWLHGLKDYQRERLVLFLDPTKDPLGGGYHLLQSTVGIGSGGLFGTGLLQGQLTKLRFIPEQHTDF
IFSALGEETGFIGTILVVTGFALLMGRLLQVAREARTDFESLVVIGVATMVMFQVVVNIFMTIGLGPVTGIPLPFMSYGR
SAMVVNFVALGLCLSVARRGHTRLNNW

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=350, Percent_Identity=34.8571428571429, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1786277, Length=365, Percent_Identity=28.7671232876712, Blast_Score=128, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 47160; Mature: 47160

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSSQRRRRNGGKSFRSKGHLRRWWKELDLVLWGVPVAMVILAGVLIASTQRQADYADWY
CCCCHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCHHHHHH
HHWITAGLGCLVALLLARLPVQRLRPLLIPLYALTVLSLVAVRLIGTSALGAQRWISIAG
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VNVQPSEFAKLAAILLLAAVLDRHPIERPIDLMRPLAVISVPWTLVFLQPDLGSSLVFGA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHH
LLVTMLYWADMPWEWVLLLLSPLATALLAGLWPWTLCAWLPLMGLLAYRSLPWKRLAASL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TLALQGIVAVTTPWLWLHGLKDYQRERLVLFLDPTKDPLGGGYHLLQSTVGIGSGGLFGT
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCCHHH
GLLQGQLTKLRFIPEQHTDFIFSALGEETGFIGTILVVTGFALLMGRLLQVAREARTDFE
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLVVIGVATMVMFQVVVNIFMTIGLGPVTGIPLPFMSYGRSAMVVNFVALGLCLSVARRG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHC
HTRLNNW
CCCCCCC
>Mature Secondary Structure
MLSSQRRRRNGGKSFRSKGHLRRWWKELDLVLWGVPVAMVILAGVLIASTQRQADYADWY
CCCCHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCHHHHHH
HHWITAGLGCLVALLLARLPVQRLRPLLIPLYALTVLSLVAVRLIGTSALGAQRWISIAG
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VNVQPSEFAKLAAILLLAAVLDRHPIERPIDLMRPLAVISVPWTLVFLQPDLGSSLVFGA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHH
LLVTMLYWADMPWEWVLLLLSPLATALLAGLWPWTLCAWLPLMGLLAYRSLPWKRLAASL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TLALQGIVAVTTPWLWLHGLKDYQRERLVLFLDPTKDPLGGGYHLLQSTVGIGSGGLFGT
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCCHHH
GLLQGQLTKLRFIPEQHTDFIFSALGEETGFIGTILVVTGFALLMGRLLQVAREARTDFE
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLVVIGVATMVMFQVVVNIFMTIGLGPVTGIPLPFMSYGRSAMVVNFVALGLCLSVARRG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHC
HTRLNNW
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]