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The map label for this gene is mrp [H]

Identifier: 33863974

GI number: 33863974

Start: 1806307

End: 1807383

Strand: Direct

Name: mrp [H]

Synonym: PMT1707

Alternate gene names: 33863974

Gene position: 1806307-1807383 (Clockwise)

Preceding gene: 33863972

Following gene: 33863975

Centisome position: 74.92

GC content: 57.01

Gene sequence:

>1077_bases
ATGGCCACGGCCGAGCAGGCACACAATGCGCTTGATCAAGTCAAGGATTCAGGCAGCGGCCGCTCGGCTCTGGAAATGGG
CTGGATTGACCAAGTCCGTGTCATTCCTCCTCGCGCCGTCATCCGCCTCACCTTGCCTGGATTTGCCCAAAGCCAAAGGG
ATCGATTGGCACAAGAAGCTCGACAAGCCTTACTAGAGCTCAACGGCATCAGTGAGGTGCAGATTGAAATTGGGGAGACT
GCCAGCCAGGGGCCTATAGGCCAGGCTGGCCATGGACAATCTGCCGAGCCCCAGGCCATCCAAGGGGTTCAGCAGATTGT
CGCCGTAAGCAGTGGTAAAGGGGGTGTTGGCAAAAGCACCGTGGCCGTCAATCTGGCCTGCGCACTAGCCCAGGAGGGCC
TAAGCGTGGGACTGCTCGATGCCGATATCTATGGACCAAATACTCCAACCATGCTTGGAGTCGCTGATCGCACGCCTGAG
GTGAGCGGCAACGGTGCTGAGCAATGCATCATCCCGATCGAAAGTCATGGGATAGCCATGGTGTCGATGGGTCTGCTAAT
CGAGGAGAACCAACCAGTGATCTGGCGCGGCCCGATGCTGAACGGGATTATCCGCCAATTCCTGTATCAGGCCTACTGGG
GGGAGCGAGATGTTTTGGTGGTCGATCTACCTCCAGGCACTGGCGATGCACAGTTGTCACTAGCGCAGGCAGTTCCCATT
GCGGGGGTGGTGATTGTCACCACCCCCCAGAAAGTTTCACTGCAGGATGCTCGCCGAGGACTGGCAATGTTCAAGCAAAT
GGGCATCAACGTGCTCGGCGTGGTCGAAAACATGACCGCCTTCGTACCTCCCGATCAACCAGAGCGTCGTTACGCCCTAT
TCGGCTCTGGAGGGGGAGAGCAGCTGGCGATGGAAAACAATGTCCCTCTGCTGGCACAAATCCCTATGGAAATGCCTGTG
CAAGAGGGGGGTAATGAAGGTAGCCCCATCGTTCATAGCCGACCCGAATCAGTGAGTGCCAAAGCCTTCAAGCAATTAGC
CAAACAAGTTCTGGATTGCGCCTCCAAGGCCAGCTGA

Upstream 100 bases:

>100_bases
TTTGTGCCAAGACAGCTCTGTTTTTGTGTCTTTTCAGATATCGCCCTTGAGAACTGTCACGAGAGTCCACACATAGGATC
CTCTCACCTGAAGGAAAGGC

Downstream 100 bases:

>100_bases
CCATGCTTTCAAGCCAGAGGCGGCGACGCAATGGTGGCAAGTCCTTCCGTTCTAAGGGGCATCTACGTAGATGGTGGAAA
GAACTGGATCTAGTGCTCTG

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MATAEQAHNALDQVKDSGSGRSALEMGWIDQVRVIPPRAVIRLTLPGFAQSQRDRLAQEARQALLELNGISEVQIEIGET
ASQGPIGQAGHGQSAEPQAIQGVQQIVAVSSGKGGVGKSTVAVNLACALAQEGLSVGLLDADIYGPNTPTMLGVADRTPE
VSGNGAEQCIIPIESHGIAMVSMGLLIEENQPVIWRGPMLNGIIRQFLYQAYWGERDVLVVDLPPGTGDAQLSLAQAVPI
AGVVIVTTPQKVSLQDARRGLAMFKQMGINVLGVVENMTAFVPPDQPERRYALFGSGGGEQLAMENNVPLLAQIPMEMPV
QEGGNEGSPIVHSRPESVSAKAFKQLAKQVLDCASKAS

Sequences:

>Translated_358_residues
MATAEQAHNALDQVKDSGSGRSALEMGWIDQVRVIPPRAVIRLTLPGFAQSQRDRLAQEARQALLELNGISEVQIEIGET
ASQGPIGQAGHGQSAEPQAIQGVQQIVAVSSGKGGVGKSTVAVNLACALAQEGLSVGLLDADIYGPNTPTMLGVADRTPE
VSGNGAEQCIIPIESHGIAMVSMGLLIEENQPVIWRGPMLNGIIRQFLYQAYWGERDVLVVDLPPGTGDAQLSLAQAVPI
AGVVIVTTPQKVSLQDARRGLAMFKQMGINVLGVVENMTAFVPPDQPERRYALFGSGGGEQLAMENNVPLLAQIPMEMPV
QEGGNEGSPIVHSRPESVSAKAFKQLAKQVLDCASKAS
>Mature_357_residues
ATAEQAHNALDQVKDSGSGRSALEMGWIDQVRVIPPRAVIRLTLPGFAQSQRDRLAQEARQALLELNGISEVQIEIGETA
SQGPIGQAGHGQSAEPQAIQGVQQIVAVSSGKGGVGKSTVAVNLACALAQEGLSVGLLDADIYGPNTPTMLGVADRTPEV
SGNGAEQCIIPIESHGIAMVSMGLLIEENQPVIWRGPMLNGIIRQFLYQAYWGERDVLVVDLPPGTGDAQLSLAQAVPIA
GVVIVTTPQKVSLQDARRGLAMFKQMGINVLGVVENMTAFVPPDQPERRYALFGSGGGEQLAMENNVPLLAQIPMEMPVQ
EGGNEGSPIVHSRPESVSAKAFKQLAKQVLDCASKAS

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=256, Percent_Identity=46.09375, Blast_Score=221, Evalue=7e-58,
Organism=Homo sapiens, GI6912540, Length=264, Percent_Identity=40.1515151515151, Blast_Score=191, Evalue=7e-49,
Organism=Homo sapiens, GI118572611, Length=260, Percent_Identity=35.7692307692308, Blast_Score=168, Evalue=6e-42,
Organism=Escherichia coli, GI87082045, Length=310, Percent_Identity=41.6129032258065, Blast_Score=236, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI25143050, Length=279, Percent_Identity=39.426523297491, Blast_Score=179, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6322188, Length=224, Percent_Identity=36.1607142857143, Blast_Score=161, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6321347, Length=259, Percent_Identity=35.9073359073359, Blast_Score=160, Evalue=2e-40,
Organism=Drosophila melanogaster, GI221511043, Length=255, Percent_Identity=39.6078431372549, Blast_Score=187, Evalue=8e-48,
Organism=Drosophila melanogaster, GI24667611, Length=258, Percent_Identity=37.984496124031, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI19921440, Length=265, Percent_Identity=32.4528301886792, Blast_Score=129, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR015223
- InterPro:   IPR002744
- InterPro:   IPR000808 [H]

Pfam domain/function: PF01883 DUF59; PF09140 MipZ; PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 37733; Mature: 37601

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATAEQAHNALDQVKDSGSGRSALEMGWIDQVRVIPPRAVIRLTLPGFAQSQRDRLAQEA
CCCHHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCCCEEEEEECCCCCHHHHHHHHHHH
RQALLELNGISEVQIEIGETASQGPIGQAGHGQSAEPQAIQGVQQIVAVSSGKGGVGKST
HHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCH
VAVNLACALAQEGLSVGLLDADIYGPNTPTMLGVADRTPEVSGNGAEQCIIPIESHGIAM
HEEHHHHHHHHCCCEEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCEEE
VSMGLLIEENQPVIWRGPMLNGIIRQFLYQAYWGERDVLVVDLPPGTGDAQLSLAQAVPI
EEEEEEEECCCCEEEECHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEHHHHCCC
AGVVIVTTPQKVSLQDARRGLAMFKQMGINVLGVVENMTAFVPPDQPERRYALFGSGGGE
CCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEHHCCEEECCCCCCCCEEEEEECCCCC
QLAMENNVPLLAQIPMEMPVQEGGNEGSPIVHSRPESVSAKAFKQLAKQVLDCASKAS
EEEECCCCCEEEECCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATAEQAHNALDQVKDSGSGRSALEMGWIDQVRVIPPRAVIRLTLPGFAQSQRDRLAQEA
CCHHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCCCEEEEEECCCCCHHHHHHHHHHH
RQALLELNGISEVQIEIGETASQGPIGQAGHGQSAEPQAIQGVQQIVAVSSGKGGVGKST
HHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCH
VAVNLACALAQEGLSVGLLDADIYGPNTPTMLGVADRTPEVSGNGAEQCIIPIESHGIAM
HEEHHHHHHHHCCCEEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCEEE
VSMGLLIEENQPVIWRGPMLNGIIRQFLYQAYWGERDVLVVDLPPGTGDAQLSLAQAVPI
EEEEEEEECCCCEEEECHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEHHHHCCC
AGVVIVTTPQKVSLQDARRGLAMFKQMGINVLGVVENMTAFVPPDQPERRYALFGSGGGE
CCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEHHCCEEECCCCCCCCEEEEEECCCCC
QLAMENNVPLLAQIPMEMPVQEGGNEGSPIVHSRPESVSAKAFKQLAKQVLDCASKAS
EEEECCCCCEEEECCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]