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The map label for this gene is clpX [H]

Identifier: 33862334

GI number: 33862334

Start: 61610

End: 62968

Strand: Reverse

Name: clpX [H]

Synonym: PMT0061

Alternate gene names: 33862334

Gene position: 62968-61610 (Counterclockwise)

Preceding gene: 33862335

Following gene: 33862333

Centisome position: 2.61

GC content: 54.16

Gene sequence:

>1359_bases
ATGGCCAAATTCGACGCCCATCTAAAGTGCTCTTTCTGCGGCAAGTCTCAGGACCAAGTACGCAAATTGATTGCTGGGCC
AGGTGTCTACATCTGCGACGAATGCATCGATCTTTGCACCGAGATCCTGGATGAAGAACTTGTCGATAGCCAAGGCAACC
CACGTCATAGCAGCGAGTCAAATCGCAAGTCTGCAACTGCTTCCCATAAAAGTGGAAAGCCAGCACCCACACTCGCCACC
ATACCCAAACCTCAGCAGATCAAAAGCTTCCTAGATAAGCAAGTGGTGGGGCAAGAAGCTGCCAAAAAAGTCCTTTCAGT
CGCCGTCTATAACCACTACAAACGCCTGGCTTGGCAAGGTGACGGCCAAGGCGAAACCGATCTCTCTGCAACCAGGCTCC
ACAAGTCAAACATCCTGCTCATCGGTCCAACAGGCTGTGGCAAAACCCTATTAGCCCAGACCCTGGCCGAACTCCTGGAC
GTGCCCTTCGCCGTTGCTGATGCAACCACACTGACCGAAGCCGGCTACGTGGGCGAGGATGTCGAAAACATTTTGCTGCG
GCTATTGCAAAAGGCCGACATGGACGTGGAGCATGCCCAGCGGGGCATCATTTACGTCGATGAGATCGATAAGATCGCCC
GAAAAAGTGAAAACCCCTCCATTACCCGCGACGTATCCGGTGAAGGAGTACAGCAAGCCCTGCTAAAGATGCTCGAAGGC
ACAGTCGCCAACGTGCCACCGCAAGGAGGGCGTAAACACCCCTATCAAGACTGCATCCAAATCGACACCAGCCAGATCCT
CTTCATCTGCGGTGGTGCCTTCATTGGCCTCGAAGATGTGGTGCAAAAGCGACTAGGCCGTAATGCCATCGGTTTTATGC
CCAGCGATGGTCGAGGGCGCAGCCGGGCCAATCGTGATCTACAGGCCTCACAGGTGCTGCACCACCTTGAAGCCGACGAC
CTCGTGCGTTATGGCTTGATCCCTGAATTCATTGGCCGCATTCCCGTGAGTGCAGTGCTTGAACCACTTGATTCACAAGC
ACTCGAATCGATACTCACGGAACCTCGTGATGCACTGGTCAAGCAATTCAGCACCCTGCTGAGCATGGACAACGTGCAGC
TTGAGTTTGAATCAGATGCCGTAGAAGCTATCGCCCAGGAAGCACATCGGCGCAAGACCGGGGCCCGAGCACTACGAGGC
ATCATCGAAGAGTTAATGCTGGATTTGATGTACGACCTTCCCTCCAAGAAGAACGTGAAGAAATTCACCGTGACCCGCAC
GATGGTTGATGAACATACCGGCGGCAAGGTGCTGCCTCTACCAGCCAACGACGAGCGATCGCATCAGGAATCAGCCTGA

Upstream 100 bases:

>100_bases
AAGGAAGGGTGACGCAACCCTGATCTGACACGATCCTGAGCGTTCAGGCTGGCCAACATTCGTCAGATCCTGTCTGCCCG
TTTGAAGTGATCACAGCCCG

Downstream 100 bases:

>100_bases
TCCAGTGGCGACGGCTGACCACCTAAAGGTGCCCCGCCAGCACGGACTTTTTTTGCATCACGGAATTGATCTTGGAGATG
GCAGCGTGGCCCACTATCTA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MAKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCTEILDEELVDSQGNPRHSSESNRKSATASHKSGKPAPTLAT
IPKPQQIKSFLDKQVVGQEAAKKVLSVAVYNHYKRLAWQGDGQGETDLSATRLHKSNILLIGPTGCGKTLLAQTLAELLD
VPFAVADATTLTEAGYVGEDVENILLRLLQKADMDVEHAQRGIIYVDEIDKIARKSENPSITRDVSGEGVQQALLKMLEG
TVANVPPQGGRKHPYQDCIQIDTSQILFICGGAFIGLEDVVQKRLGRNAIGFMPSDGRGRSRANRDLQASQVLHHLEADD
LVRYGLIPEFIGRIPVSAVLEPLDSQALESILTEPRDALVKQFSTLLSMDNVQLEFESDAVEAIAQEAHRRKTGARALRG
IIEELMLDLMYDLPSKKNVKKFTVTRTMVDEHTGGKVLPLPANDERSHQESA

Sequences:

>Translated_452_residues
MAKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCTEILDEELVDSQGNPRHSSESNRKSATASHKSGKPAPTLAT
IPKPQQIKSFLDKQVVGQEAAKKVLSVAVYNHYKRLAWQGDGQGETDLSATRLHKSNILLIGPTGCGKTLLAQTLAELLD
VPFAVADATTLTEAGYVGEDVENILLRLLQKADMDVEHAQRGIIYVDEIDKIARKSENPSITRDVSGEGVQQALLKMLEG
TVANVPPQGGRKHPYQDCIQIDTSQILFICGGAFIGLEDVVQKRLGRNAIGFMPSDGRGRSRANRDLQASQVLHHLEADD
LVRYGLIPEFIGRIPVSAVLEPLDSQALESILTEPRDALVKQFSTLLSMDNVQLEFESDAVEAIAQEAHRRKTGARALRG
IIEELMLDLMYDLPSKKNVKKFTVTRTMVDEHTGGKVLPLPANDERSHQESA
>Mature_451_residues
AKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCTEILDEELVDSQGNPRHSSESNRKSATASHKSGKPAPTLATI
PKPQQIKSFLDKQVVGQEAAKKVLSVAVYNHYKRLAWQGDGQGETDLSATRLHKSNILLIGPTGCGKTLLAQTLAELLDV
PFAVADATTLTEAGYVGEDVENILLRLLQKADMDVEHAQRGIIYVDEIDKIARKSENPSITRDVSGEGVQQALLKMLEGT
VANVPPQGGRKHPYQDCIQIDTSQILFICGGAFIGLEDVVQKRLGRNAIGFMPSDGRGRSRANRDLQASQVLHHLEADDL
VRYGLIPEFIGRIPVSAVLEPLDSQALESILTEPRDALVKQFSTLLSMDNVQLEFESDAVEAIAQEAHRRKTGARALRGI
IEELMLDLMYDLPSKKNVKKFTVTRTMVDEHTGGKVLPLPANDERSHQESA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=303, Percent_Identity=50.1650165016502, Blast_Score=288, Evalue=7e-78,
Organism=Escherichia coli, GI1786642, Length=424, Percent_Identity=56.8396226415094, Blast_Score=473, Evalue=1e-134,
Organism=Escherichia coli, GI1790366, Length=218, Percent_Identity=30.7339449541284, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71982908, Length=306, Percent_Identity=45.0980392156863, Blast_Score=265, Evalue=5e-71,
Organism=Caenorhabditis elegans, GI71982905, Length=293, Percent_Identity=47.098976109215, Blast_Score=264, Evalue=7e-71,
Organism=Caenorhabditis elegans, GI71988663, Length=412, Percent_Identity=37.621359223301, Blast_Score=241, Evalue=8e-64,
Organism=Caenorhabditis elegans, GI71988660, Length=256, Percent_Identity=40.234375, Blast_Score=167, Evalue=8e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=458, Percent_Identity=37.3362445414847, Blast_Score=259, Evalue=6e-70,
Organism=Drosophila melanogaster, GI24648289, Length=295, Percent_Identity=50.1694915254237, Blast_Score=284, Evalue=9e-77,
Organism=Drosophila melanogaster, GI24648291, Length=295, Percent_Identity=50.1694915254237, Blast_Score=284, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 49549; Mature: 49418

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCTEILDEELVDSQGNPRHSSES
CCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
NRKSATASHKSGKPAPTLATIPKPQQIKSFLDKQVVGQEAAKKVLSVAVYNHYKRLAWQG
HHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DGQGETDLSATRLHKSNILLIGPTGCGKTLLAQTLAELLDVPFAVADATTLTEAGYVGED
CCCCCCCCHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHH
VENILLRLLQKADMDVEHAQRGIIYVDEIDKIARKSENPSITRDVSGEGVQQALLKMLEG
HHHHHHHHHHHCCCCHHHHHCCCEEHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCC
TVANVPPQGGRKHPYQDCIQIDTSQILFICGGAFIGLEDVVQKRLGRNAIGFMPSDGRGR
HHCCCCCCCCCCCCHHHHHHCCCHHEEEECCCHHCCHHHHHHHHHCCCCCCCCCCCCCCC
SRANRDLQASQVLHHLEADDLVRYGLIPEFIGRIPVSAVLEPLDSQALESILTEPRDALV
HHHCCCHHHHHHHHHCCHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHH
KQFSTLLSMDNVQLEFESDAVEAIAQEAHRRKTGARALRGIIEELMLDLMYDLPSKKNVK
HHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
KFTVTRTMVDEHTGGKVLPLPANDERSHQESA
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
AKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCTEILDEELVDSQGNPRHSSES
CCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
NRKSATASHKSGKPAPTLATIPKPQQIKSFLDKQVVGQEAAKKVLSVAVYNHYKRLAWQG
HHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DGQGETDLSATRLHKSNILLIGPTGCGKTLLAQTLAELLDVPFAVADATTLTEAGYVGED
CCCCCCCCHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHH
VENILLRLLQKADMDVEHAQRGIIYVDEIDKIARKSENPSITRDVSGEGVQQALLKMLEG
HHHHHHHHHHHCCCCHHHHHCCCEEHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCC
TVANVPPQGGRKHPYQDCIQIDTSQILFICGGAFIGLEDVVQKRLGRNAIGFMPSDGRGR
HHCCCCCCCCCCCCHHHHHHCCCHHEEEECCCHHCCHHHHHHHHHCCCCCCCCCCCCCCC
SRANRDLQASQVLHHLEADDLVRYGLIPEFIGRIPVSAVLEPLDSQALESILTEPRDALV
HHHCCCHHHHHHHHHCCHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHH
KQFSTLLSMDNVQLEFESDAVEAIAQEAHRRKTGARALRGIIEELMLDLMYDLPSKKNVK
HHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
KFTVTRTMVDEHTGGKVLPLPANDERSHQESA
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA